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May 7, 2019 by admin 0 Comments

Post Cycle Therapy & well-Structured Testosterone Therapy

The Post Cycle Therapy (PCT), and Testosterone Injections Therapy goes hand on hand, Most men embarking on a testosterone injectable therapy replacement protocol are doing so as a result of medical reason or age-related issues that are affecting their life.

Now patients with problems and that face their low testosterone, the related concerns and do not allow fully experience the decline associated with maintaining extended periods of low hormones levels and will usually benefit from comprehensive testosterone therapy.

Note: that the specific drug and dose prescribed will depend on the particular information contained within each patient medical file and medical reason, as well as the individual goals patients.

Example:

  • Day 1. (50–250 mg) of testosterone injection.
  • Day 2. Two estrogen blocker or inhibitor.
  • Day 3. One injectable of an amino acid or vitamin B-vitamin.
  • Day 5. One estrogen blocker or inhibitor by mouth.
  • Day 6. One injection of a (250–800 units) of testosterone secretagogue.
  • Day 7. One estrogen blocker or inhibitor (sometimes two estrogen blockers a week is enough, But depending on the patient file).
  • Day 7. One injection of a (250–800 units) of testosterone secretagogue.

Example: This protocol for a man focused on muscle development (reversing lean muscle loss), Muscle development protocols, also work well in patients that may react to therapy with too much aromatization (estrogen accumulation).

Men are experiencing excessive aromatization and lean muscle depletion who are focused on rebuilding muscle, with Peptides.

Note: that the specific drug and dose prescribed will depend on the particular information contained within each patient medical file, as well as the individual patient goals.

Example:

  • Day 1. (50–150 mg) of a combination of testosterone esters,
    (15–30 units) Sermorelin Peptides before Bedtime.
  • Day 2. Two estrogen blocker or inhibitor,
    (15–30 units) Sermorelin Peptides before Bedtime.
  • Day 3. One injection of an amino acid or B-vitamin,
    (15–30 units) Sermorelin Peptides before Bedtime.
  • Day 4. Combination of (50–150 mg) testosterone esters,
    (15–30 units) Sermorelin Peptides before Bedtime.
  • Day 5. One estrogen blocker or inhibitor by mouth,
    (15–30 units) Sermorelin Peptides before Bedtime.
  • Day 6. One injection of a (250–800 units) of testosterone secretagogue.
  • Day 7. One estrogen blocker or inhibitor (sometimes two estrogen blockers a week is enough, But depending on the patient file).
  • Day 7. One injection of a (250–800 units) of testosterone secretagogue.

This weekly cycle would typically continue for 6–9 months, before a break period in which the body is allowed to normalize and reactivate your natural production.

What is Sermorelin?

Sermorelin is a peptide comprised of the first 29 amino acids of endogenous GH; the sequence is the same as endogenous GHRH. As we age, our body produces less and less of our vital hormones, including GH. Studies have revealed that sermorelin can restore GH RNA concentrations to youthful levels, which subsequently stimulates the production of insulin-like growth factor-1 (IGF-1).

Remember: When you are artificially manipulating your testosterone levels, some other functions of the body stop operating since endogenous testosterone production is shut down because of the presence of high levels of exogenous hormone. You will need Post Cycle Therapy on your break from testosterone therapy.

Break Period: Generally referred to as the Post Cycle Therapy (PCT), consists of medications that are formulated to reactivate the dormant systems that we have not used while your testosterone Injections therapy.

The essential functions that need to reactivate with your
Post Cycle Therapy:

  • FSH (follicle-stimulating hormone): This will stimulate sperm production in the testes.
  • LH (luteinizing hormone): This will stimulate testosterone production in the testes.

The reason why is because estrogen accumulation after extended periods of high testosterone levels, and water retention can cause, decreased libido, and other side effects associated with high estradiol levels from past testosterone therapy.

Well-structured Testosterone Injection Therapy

Following Results:

  • Week One: If you have never received testosterone injections before and are suffering from hypogonadism (clinically low testosterone), you should begin to experience invaluable changes just 3 or 4 days after your first administration. You should sleep better and have more energy.
  • Week Two: Morning erections make a significant comeback! In men with erectile dysfunction problems, morning erections help to determine if their problems stem from a psychological or a physiological problem.
  • Week Three: You will begin to notice a sense of clarity as your cognitive function improves. Your ability to recall information and your articulation will improve. You will suddenly realize that you feel more mentally sharp and able, which will allow you to better cope with stress and pressure.
  • The End of Month One: Your energy levels should be noticeably increased throughout the day.
  • Month Two: The same health manifestations that you were experiencing throughout your first month should continue to develop and improve. Your energy levels should still be increasing, and you should have a stronger “go-getter” attitude.
  • Month Three: There should now be a significant, noticeable difference in your energy level and output. Your workouts will require less effort and will yield quicker, more visible results. The time you need for muscle healing and recuperation after exercise should be reduced.
  • Month Four: By now, your endurance, stamina, exercise potential, and overall performance ability should supersede all your expectations. If you have never been on testosterone therapy before your first program and you have been eating well and exercising from the beginning, you will be surprised at the level of transformation you have experienced. Furthermore, it will be evident that these results and this amount of energy output would not be possible without restoring your testosterone levels to the numbers had in your youth.
  • Month Five: The changes and improvements in your physical performance, ability, and growth will be fantastic. If you were experiencing mental problems such as sadness, depression, anxiety, or even mental fatigue, by now you should notice substantial progress in your ability to deal with unpleasant or challenging scenarios and circumstances. Remember that all the other positive changes you have experienced will also contribute to a sense of self-improvement. This makes you naturally feel better about your progression and growth. More importantly, the physiological changes in brain chemical secretion add to your sense of fulfillment, happiness, and overall well-being.
  • Month Six: All individuals are receiving testosterone experience different effects by six months of therapy. What you experience will also depend on how many cycles of testosterone therapy you have participated in previously. Sometimes, a user’s sense of improvement begins to dwindle or remain stagnant. The body can become used to the type, or ester, of testosterone that is being used if the same therapy is continued for more than 1 or 2 years. Also, because other processes in the body cease to function when testosterone levels are manipulated using testosterone injections, the benefits of therapy begin to diminish and the “feel good” scenarios that were being experienced stopped.

Well-structured Sermorelin Therapy:

Month one:

  • Increased energy
  • Deeper, more restful sleep
  • Improved stamina
  • A more content state of mind

Month Two:

  • Reduced belly fat
  • Improved metabolism
  • The return of some muscle tone
  • Improved skin tone and fewer wrinkles
  • Stronger hair and nails

Month Three:

  • Increased mental focus
  • Improved flexibility and joint health
  • More feelings of drive and ambition
  • Enhanced sex drive and performance

Month Four:

  • Improved mental acuity
  • Better skin elasticity
  • Further improved appearance of the hair and nails
  • Continued weight loss
  • Increased lean muscle mass

Month Five:

  • Continued loss of belly fat
  • Improved skin tone with the reduced appearance of wrinkles
  • Noticeably fuller, healthier hair

Month Six:

  • A 5–10% reduction in body fat, without diet or exercise
  • A 10% increase in lean muscle mass
  • Significantly improved physique
  • Increased vitality dies to organ regrowth (vital organs, including the brain, shrink with age)

March 4, 2019 by Joseph Fermin 0 Comments

What is Luteinizing Hormone (LH) and Testosterone

What is Luteinizing Hormone &
The Productions of Testosterone

If you google the word Luteinizing Hormone or (LH), most of the articles you will find talks about the role of luteinizing hormone in women. There is very no info about the part of Luteinizing Hormone in men. While it may seem like a female hormone due to its role in ovulation, a surge of Luteinizing Hormone is a trigger that causes the ovary to release the egg, in the body. If you’ve been trying to conceive or have a baby your wife, significant other may be monitoring her Luteinizing Hormone levels. If she has trouble with ovulation, your doctor may prescribe medications that help with ovulation.

Many of this medication help stimulate the body to produce more Luteinizing Hormone (LH) and its cousin hormone, Stimulating Follicle Hormone (FSH). If you are not trying to conceive, or get pregnant, she may be on hormonal birth control pills. These pills prevent ovulation by blocking Stimulating Follicle Hormone and Luteinizing Hormone. It is one of the manliest hormones in your body. You can think of Luteinizing Hormone as a tiny drill sergeant that commands the Leydig Cells in the testicle to produce testosterone. When Luteinizing Hormone is present, the Leydig Cells generate Testosterone, when it is not, they don’t. Luteinizing Hormone is commander and chief of your Testosterone and critically crucial for sperm production count, muscle building, and overall sexual health.

Male hormones have a clinical nature to them. Luteinizing Hormone (LH) signals the testicle to produce Testosterone. Testosterone seeps out of the testis and into the bloodstream, where it circulates the body and put to good use. Manly things like growing chest hair, increase muscle and your voice deep are some of the effects.

Luteinizing Hormone or (LH)

The brain monitors the blood testosterone levels;

  • If they drop too low, it will send a signal to the pituitary gland to send out more Luteinizing Hormone (LH) to kick start testosterone production.
  • If your testosterone is chronically low (as in the case with hypogonadism or Low Testosterone), the brain will respond by increasing the level of Luteinizing Hormone (LH).
  • If testosterone is chronically higher (as in the case with using testosterone therapy, other performance enhancers or steroids), the brain will shut down production of Luteinizing Hormone (LH). When testosterone therapy is stopped, without post-therapy, men can experience a “crash” as Testosterone levels plummet, but with a post-therapy, the brain lags in re-starting the machinery to generate Luteinizing Hormone.

Getting Tested:

To measure Luteinizing Hormone (LH) levels, you will need to get blood work in a hormone clinic done. Because, doctors will order blood to estimate a panel of hormones which usually includes Stimulating Follicle Hormone, Luteinizing Hormone, Testosterone, Estrogen and They may also add Estrodial, Prolactin which will provide additional information into the insight into your hormonal health and a physical to know your body composition.

In a typical day, Luteinizing Hormone (LH) and Testosterone levels cycle from high to low. When getting blood work done to measure hormone levels, it is important to note the time of day that the analysis was performed to understand the values better.

Testosterone naturally will peak first thing in the morning (partially responsible for morning “wood”). For this reason, doctors prefer to regulate hormones between 8-10am to get a snapshot of your hormone panel profile when Testosterone level is likely to be highest.

When preparing for a Luteinizing Hormone test and to sure your doctor is aware of a few things like:

  • Current Prescription Taking: Current or past use of testosterone therapy. (If you are using anything at the gym or in supplements stores and you aren’t quite sure), you should bring it with your doctor about the appointment.
  • The Use Of Marijuana or THC: It may decrease the number of hormones levels, including Luteinizing Hormone.
  • Medical Radioactive Tracer: This can interfere with the test
  • Normal levels Luteinizing Hormone Range For Adult Males: 1–10 mIU/mL.

They are different labs report different reference ranges, and based on the exact way that they perform the blood work test. From a review of various lab reports, Values lower than 1.0 or higher than 10.0 typically indicate some problem.

For average men, Luteinizing Hormone (LH) typically falls somewhere between 4-7mIU/mL with drops and surges (about 6) throughout the day. Values below 4 and above seven may be considered borderline, and are useful to look at when compared to other hormones, particularly Testosterone and Prolactin.

In the studies that we have reviewed and found that these types of conditions have shown, and can significant drops in testosterone levels and minimal effect in Luteinizing Hormone (LH). Occasionally, Luteinizing Hormone may show up a little low, but often it is entirely in the normal range.

Therefore, low testosterone levels accompanied with normal Luteinizing Hormone (LH) levels often indicate the cause of Low Testosterone can tremendously help to diagnose the condition and also help to create a game plan for treating the cause while managing symptoms of low Testosterone.untitled-design-16

Whats the Causes of high Luteinizing Hormone in Men?

If Luteinizing Hormone (LH) is high and testosterone is low. Then some damage is causing the testicle, or the pituitary gland is trying to compensate by going into overdrive and flooding the balls. With extra Luteinizing Hormone in hopes that it will encourage higher Testosterone production. In cases like this, Luteinizing Hormone levels are often off the charts high sometimes double or triple the average values.

Common causes for this include:

  • Chromosome Abnormalities: Such as Klinefelter’s syndrome
  • Childhood Problems: Such as testicle or testicular torsion, The injury that causes significant damage to testicular tissue
  • Viral Infection: (most commonly mumps) that damages the testis.
  • Radiation exposure or chemotherapy
  • Testicular cancer
  • Borderline High Luteinizing Hormone (LH) levels

Medications or untreated autoimmune disorders can cause slightly elevated Luteinizing Hormone (LH) levels (8.0 – 10.0 range). Some studies have linked Celiac’s Disease with elevated somewhat Luteinizing Hormone (LH). Men with the untreated disease can have moderately high Luteinizing Hormone levels, that usually return to normal upon starting a gluten-free diet.

What causes low Luteinizing Hormone in Men?

The most common reason for Luteinizing Hormone deficiency in men is the use of external androgens (testosterone, other performance enhancers or non-medication). External androgens can trick the brain into thinking the body is producing naturally high levels of testosterone which low down production of luteinizing hormone (LH) and consequently natural testosterone production.

The second most common cause of low Luteinizing Hormone (LH) levels is a health issue, and can directly impact the function of the pituitary in the brain, Most common causes of the pituitary malfunction can include genetic conditions, such as Prader-Willi Syndrome or Kallman’s Syndrome and can cause other problems like:

  • Pituitary tumors (cancerous and benign)
  • Hyperprolactinemia
  • Head trauma
  • Various Medications
  • Auto-immune disorders
  • Borderline low Luteinizing Hormone (LH) results

Luteinizing Hormone levels in the 1.0 – some things can cause 3.0 range. Like, reduce temporarily imbalance hormones: such as overtraining, endurance. They are significantly under or overweight Alcohol consumption spikes in insulin medications or other drugs. High-stress Chronic conditions: that can cause hormone imbalance: such as diabetes, insulin resistance, various auto-immune disorders and can create borderline or low levels of Luteinizing Hormone (LH).

 

January 28, 2019 by Joseph Fermin 0 Comments

The importance of Testosterone Post Cycle Therapy?

Why Is Testosterone
Post Cycle Therapy Is Need It?

Why is Post Cycle Therapy (PCT) is perhaps the most critical aspect of testosterone use? The concept of the post cycle therapy (PCT), did not exist before the late 1980s, and 1990s and the mechanisms by which testosterone affected, the body were not wholly understood during the 1950s, 1960s, and 1970s.

This period were doctors, scientists, and testosterone injections users were only beginning to learn about the dynamics of testosterone and how they affect the endocrine system. We believed and understood since the beginning of testosterone injections use, the administration of testosterone resulted in triggering the body’s negative loop of the (HPTA) Hypothalamic Pituitary Testicular Axis. That endogenous Testosterone production would result become suppressed and shut down. The, unfortunately, is during the early periods of testosterone use between the 1950s and 1990, there was limited access to the compounds or knowledge or effectively.

Today it is a very different story. Now scientific and medical understanding of bio-identical testosterone use has soared exponentially since the old ‘golden era’ days of looking young and testosterone therapy use in athletics. Countless developments of beneficial compounds for hormonal recovery after testosterone therapy use, alongside the increased scientific and medical knowledge, has enabled testosterone use and its associated endocrine disruptions. The proper knowledge on how to recover the body’s from Hypothalamic Pituitary Testicular Axis (HPTA). Through post cycle therapy (PCT), we can not only emerge from their testosterone therapy while holding on to almost all of their benefits, but they can also increase the chances upwards to 90 percent or higher range of emerging with a fully healthy (HPTA).

Following the use of exogenous testosterone injections, the majority of users will experience what has been a hormonal crash or post cycle therapy crash, which is a physical environment in which key hormones essential is has been suppressed or shut down. The critical hormones in question are Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH), and subsequently (and are most importantly), for our natural testosterone. The Luteinizing Hormone (LH), and the Follicle Stimulating Hormone (FSH), known as phototropism. These hormones increase Testosterone secretion. Also alongside low levels of these hormones, to balance the essential hormones that have been thrown off balance, whereby Testosterone levels will be small, and most of the time, depending on the factors, estrogen levels will be higher than usual, and levels of Cortisol a steroid hormone that destroys muscle tissue. With the testosterone levels low and Cortisol levels in the average or high, Cortisol now can become a threat to the new muscle during the new testosterone therapy (“Testosterone correctly suppresses and counteracts Cortisol’s catabolic effects on muscle tissue”). The SHBG (Sex Hormone Binding Globulin) is also a concern here as well, which is a protein that binds to sex hormones Testosterone renders them inactive, essentially ‘handcuffing’ them and preventing them from exerting their effects. SHBG will also usually elevated during the post cycle therapy weeks as a result of the supraphysiological levels of androgens from the new testosterone therapy.

The human body will generally and restore this imbalance of hormones and recover from testosterone levels on its own, over time with no outside assistance or post cycle therapy (PCT), but the studies have demonstrated and shown us that without the intervention of testosterone stimulating agents, this will occur throughout one to four months. Therefore, all testosterone therapy should be concerned with the fastest possible hormonal recovery, assisted and boosted with the use of Testosterone stimulating compounds correctly, also the attempt to allow the body to recover on its own, from a very high probability of long-term endocrine damage to the Hypothalamic Pituitary Testicular Axis (HPTA), whereby the individual will develop-induced hypogonadism to inability the production of proper levels of Testosterone to rest. So therefore paramount that an appropriate post cycle therapy that includes multiple recovery compounds to be utilized to not only restore the (HPTA) function but also to normalize the levels as quickly as possible. To avoid any possible permanent damage, which can take priority over the concern of maintain to the recently gained muscle mass and any other benefits from it.

What Post Cycle Therapy Protocol?

There are many different types of post cycle therapy (PCT) protocols that have overdeveloped over the years; any individual will become extremely confused about how many different opinions exist among the testosterone community, This article will present the best possible and most efficient post cycle therapy protocol valid scientific data, also myths in regards to post cycle therapy (PCT), and outline which post cycle therapy (PCT) protocols should not follow due to recent more advanced developments, as well as contemporary better scientific and medical understandings of how a proper post cycle therapy protocol should work. This point, there still exists very obsolete – and subsequently ineffective – post cycle therapy (PCT) contracts that are still utilized by many testosterone users, and this presents a severe hazard not only for the individual unknowingly using a post cycle therapy.

For example:

There are several therapeutic and safety reasons why you should not continue with testosterone injections indefinitely without giving your body time to normalize to reset. Because of the decline in benefits after six months of a testosterone therapy, the physicians need to regularly incorporate a cleanse therapy post cycle therapy (PCT) in an attempt to reactivate the endocrine in the body, as you increase your testosterone levels using any testosterone therapy, now the levels of testosterone circulating the body will shut down the natural production of your endogenous testosterone; and also increases the production of estrogen in your body, which can lead to a series of undesirable and unwanted side effects in the body. `This means that the synthesis of (LH) luteinizing hormone in your body; this hormone is produced by your brain to stimulate testosterone production. and follicle-stimulating hormone in the body; the hormone produced by your mind to boost sperm production suddenly stops. When Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) levels are no longer detectable, your body will not experience the exceptional health benefits, and energy-optimizing results expected from a testosterone injection program.

Another critical concern for men is testicular atrophy in patients that participate in testosterone therapy and may experience shrinkage of the testes, This occurs as the result of the lack of testosterone, and sperm production has been shut down, in response to the testosterone therapy.

What does post cycle therapy (PCT) consist of, an example?

Your post cycle therapy consists of a testosterone secretagogue to stimulate the secretion of endogenous testosterone from the testes to reignite natural production. The medication mimics the signal from your brain. The Luteinizing Hormone (LH) induce the production of testosterone. An example of a testosterone secretagogue is human chorionic gonadotropin (hCG), which is administered either using sublingual troches or subcutaneous injections once or twice a week during therapy and then on 10–15 consecutive days as part of a post cycle therapy (PCT). Human chorionic gonadotropin (hCG), mimics Luteinizing Hormone (LH) to stimulate testosterone production by the testes. It works by effectively tricking the testes into thinking that they are being instructed to produce testosterone, even though levels are comfortably elevated because of the injectable testosterone therapy. The testosterone production stimulated by human chorionic gonadotropin (hCG) is not sufficient to sustain healthy testosterone levels on its own, but that is not the reason for this supplementation. The purpose is to ensure that the testes remain functioning during therapy to help avoid any shrinkage or atrophy.

You will also take an anti-estrogen or aromatase inhibitor. For example, Clomid/clomiphene blocks certain types of estrogen from getting to the pituitary and hypothalamus, where it elicits signals that stop testosterone production. Anti-estrogens or aromatase inhibitors also help to reactivate the standard functionality of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) signaling, while also helping to flush out any residual estrogen that has accumulated during therapy. The estrogen that collects during treatment is responsible for many of the adverse side effects associated with testosterone therapy.

An example of a post cycle therapy (PCT) protocol is as follows (note that the exact drug and dose prescribed will depend on the specific information contained within each patient file, as well as the individual patient goals):

  • 250–800 units of a testosterone secretagogue every day for ten consecutive days
  • One estrogen blocker or antagonist by mouth every day for 10–15 straight days

Without the proper understanding of what is explicitly occurring within the endocrine system during these crucial weeks, as well as a lack of knowledge of which compounds to utilize, what each compound does, and how to properly use them, serious problems can result.

post cycle therapy

The Hypothalamic Pituitary Testicular Axis (HPTA):

The (HPTA), which is an axis interconnected endocrine glands in the body that deals with control the production Testosterone.

Post-Cycle-therapy:

Outlined above is a diagram of the Hypothalamic Pituitary Testicular Axis (HPTA), Regulates the body produces the amount of Testosterone at any given time. Every individual is essentially programmed by (DNA) genetics as to maximum Testosterone they will provide.

The Hypothalamic Pituitary Testicular Axis (HPTA) and the functions that undergo a negative feedback loop, and the body will reduce secretion of Testosterone, f have too much Testosterone the body will be detected, known as the negative feedback loop. This controlled by the hypothalamus, which is mostly considered the ‘master’ gland for all endocrine system and the hormonal functions in the body. The negative feedback will loop ultimately in the body to attempt to maintain the hormonal homeostasis, and all endocrine glands operate by way of the negative feedback loop in one way or another in varying degrees, In the case of post cycle therapy, the concern is a negative feedback loop of the (HPTA).

Within the Hypothalamic Pituitary Testicular Axis (HPTA), the concern during post cycle therapy (PCT) is the restoration and regulation of the following five hormones to homeostasis:

  • GnRH (Gonadotropin Releasing Hormone)
  • LH (Luteinizing Hormone)
  • FSH (Follicle Stimulating Hormone)
  • Testosterone production

The Hypothalamic Pituitary Testicular Axis (HPTA), the hypothalamus, which will detect a need for the human body to produce more Testosterone, and will release varying amounts of GnRH, Is a hormone that signals the pituitary gland, to begin the production and release of two essential gonadotropins: Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH). Two hormones that work together to start the secretion of Testosterone.

Two primary hormonal factors serve to inhibit, reduce, suppress, or shut down Testosterone production in the Hypothalamic Pituitary Testicular Axis (HPTA):

  • Testosterone Excess
  • Estrogen Excess

Although there exist other hormones that serve to inhibit and suppress Hypothalamic Pituitary Testicular Axis (HPTA) function (such as Progestins and Prolactin), these are the two primary conditional hormones that are of concern. When the hypothalamus detects excess levels of Testosterone and Estrogen in the body (either from the use of exogenous androgens on an testosterone therapy or otherwise), the hypothalamus will act to attempt to restore a balance by essentially doing the opposite of what was previously described. The hypothalamus will reduce or stop its production of GnRH, which halts production of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH), which ultimately reduces or halts production of Testosterone. Until the hypothalamus’ ideal hormonal environment is restored, the output of the various signaling hormones within the (HPTA) will not begin, and this will often require months for the body to do this on its own without the intervention of any Testosterone stimulating agents. The reason as to why the recovery of the (HPTA) naturally takes such a long time should be very clear due to the described workings of the (HPTA).

This fundamental understanding of the mechanisms of the Hypothalamic Pituitary Testicular Axis (HPTA) and negative feedback loop described above is essential to understanding how and why a proper post cycle therapy (PCT) program must be developed and utilized following an testosterone therapy.

Determining Factors In Difficulty Recovering the Hypothalamic Pituitary Testicular Axis (HPTA):

With testosterone therapy use, there are several different major determining factors in how much difficulty an individual will experience in recovery of their Hypothalamic Pituitary Testicular Axis (HPTA) and endogenous Testosterone function during post cycle therapy (PCT).

They are the following factors, in no particular order of importance:

  • Individual response
  • Type of testosterone(s) used
  • Length of the cycle (degree of testicular desensitization)

Individual response:

Every single individual will respond differently to any chemical, compound, testosterone, food or drug in existence. While some individuals might experience no Hypothalamic Pituitary Testicular Axis (HPTA) suppression or shutdown at all, other individuals might experience severe Hypothalamic Pituitary Testicular Axis (HPTA) suppression and closure to the extent where they might require far more extended periods to ensure full recovery than most. This, like anything else, is a spectrum whereby there are the very ‘lucky’ individuals that recover very quickly and easily on one end of the spectrum, and the ‘unlucky’ individuals that have extreme difficulty recovering during post cycle therapy. In between the two extremes is the average. Once again, this is due to the individual’s genetic programming as to how the Hypothalamic Pituitary Testicular Axis (HPTA) will respond and attempt to maintain homeostasis.

Type of Testosterone Therapy(s) used:

All testosterone therapy exhibit suppression or shutdown of the Hypothalamic Pituitary Testicular Axis (HPTA) through the mechanisms of the negative feedback loop, and there are no exceptions to this. Various testosterone therapy are known as being mildly suppressive, while others are identified as being profoundly suppressive. This is all reliant on multiple different reasons, many of which will not be discussed here. In any case, no matter how mild or severe an testosterone therapy exerts Hypothalamic Pituitary Testicular Axis (HPTA) suppression, all testosterone therapy when utilized for typical cycle lengths of weeks at a time will eventually cause the Hypothalamic Pituitary Testicular Axis (HPTA) to shut down, or at the very least severely suppress its hormonal signal processes.

Length of the cycle degree of testicular desensitization:

This is perhaps the most important and most influential factor. As the range of testosterone therapy use continues, the majority of the Leydig cells of the testes remain dormant and inactive, and the longer these interstitial cells stay dormant and idle, the higher the difficulty is essentially getting these cells to respond to the stimulus of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) once again. It has been discovered in studies that the issue of recovery of the Leydig cells following testosterone therapy use is not due to a lack of Luteinizing Hormone (LH), but due instead to the desensitization of the Leydig cells to (LH). In one study in which exogenous Testosterone was administered to male test subjects for 21 weeks, Luteinizing Hormone (LH) levels were suppressed shortly after beginning administration. However, at the end of the 21 weeks, Luteinizing Hormone (LH) levels were observed to rise within three weeks once the exogenous Testosterone administration stopped, but Testosterone levels did not arise until many weeks later in most of the test subjects.

Recovery During The Post Cycle Therapy (PCT).

To stimulating hormonal recovery during post cycle therapy, it is essential for individuals to understand that the use of any medication except for a single select one or two is inadequate for hormonal recovery during post cycle therapy (PCT). Ideally, all post cycle therapy programs should be a multi-component post cycle therapy (PCT) program that includes several different compounds that work in tandem with one another to provide the most effective and fastest possible Hypothalamic Pituitary Testicular Axis (HPTA) recovery following an testosterone therapy.

The three categories of compounds are in order of importance:

  • SERMs (Selective Estrogen Receptor Modulators)
  • Aromatase Inhibitors
  • HCG (Human Chorionic Gonadotropin)

SERMs:

Classes of drugs in the SERM category include: Nolvadex (Tamoxifen Citrate), Clomid (Clomiphene Citrate), Raloxifene, and Fareston (Toremifene Citrate). The nature of a SERM is that it exhibits mixed Estrogen agonist and Estrogen antagonist effects on the body. This means that although a SERM might block the effect of Estrogen at the cellular level in specific tissues, it can enhance Estrogenic impacts in other areas of the body. These can be positive effects as well as adverse effects. Nolvadex, for example, exhibits Estrogenic agonistic effects in the liver, which is a positive effect, as its effects here result in a positive change in cholesterol profiles (something desired by many). All SERMs to varying degrees serve to act as an Estrogen antagonist in this area, working to mitigate Estrogen’s effects on breast tissue, reducing or blocking the side effect of gynecomastia. Regarding the impact of SERMs on endogenous Testosterone stimulation, they serve to act as an Estrogen antagonist at the pituitary gland, triggering the release of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) as a result. Elevated levels of Estrogen in men can and does suppress the output of endogenous Testosterone via the negative feedback loop, leading to hypogonadism. SERMs for this purpose are an essential addition to any post cycle therapy (PCT) protocol and are not to be excluded under any circumstance. Regardless of this, however, the sole focus should not be on SERMs.

Aromatase Inhibitors:

These are compounds such as Aromasin (Exemestane), Arimidex (Anastrozole), and Letrozole (Femara). Rather than block the activity of Estrogen at the cellular level in different tissues, aromatase inhibitors (AIs) serve to lower total circulating Estrogen levels in the body by way of inhibiting the aromatase enzyme, which is the enzyme responsible for the conversion of androgens into Estrogen. The transformation of androgens into Estrogen results in excess Estrogen levels, which, as explained earlier in this article, will trigger the negative feedback loop leading to suppression of Testosterone production. By way of lowering total circulating blood plasma Estrogen levels, AIs will positively engage the negative feedback loop and result in the release of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) for the manufacture and secretion of more Testosterone. This is mainly due to the hypothalamus realizing that circulating. Estrogen levels are too low and will attempt to increase circulating levels of Testosterone for a portion of the Testosterone secreted to be able to become aromatized into Estrogen to restore the hormonal balance. The other importance of aromatase inhibitors is the ability to mitigate the Estrogenic effects of human chorionic gonadotropin (HCG), which will be explained shortly. It is important to note, however, that the majority of aromatase inhibitors do not comply very well with SERMs such as Nolvadex, and those particular choices should be made in regards as to which AI is used during post cycle therapy (PCT).

HCG:

Human Chorionic Gonadotropin is, for the most part, synthetic Luteinizing Hormone (LH). It is a protein hormone manufactured in high amounts by pregnant females that contains a protein subunit that is 100% identical to Luteinizing Hormone (LH), and therefore when administered to men, it will mimic the action of Luteinizing Hormone (LH) in target tissues, such as the testes. What results is an increase in Testosterone production via stimulation of the Leydig cells by human chorionic gonadotropin (HCG). Human chorionic gonadotropin (HCG) should never be utilized alone, as its nature as a gonadotropin will itself trigger a negative feedback loop whereby once human chorionic gonadotropin (HCG) is used, the pituitary gland will halt output of Luteinizing Hormone (LH) until human chorionic gonadotropin (HCG) use has discontinued. Therefore, human chorionic gonadotropin (HCG) must be utilized with a SERM and especially an aromatase inhibitor, as human chorionic gonadotropin (HCG) has demonstrated to increase aromatase activity in the testes, resulting in rising Estrogen levels.

Putting Them Together:

The reader may be wondering which compounds to select of the three categories listed, and how to use them properly. The answer lies in understanding the properties of each and, in interpreting these properties, how to use them efficiently and appropriately.

Human chorionic gonadotropin (HCG):

The first item to be examined will be human chorionic gonadotropin (HCG). The majority of testosterone therapy users from the 1960s – mid-1980s did not even utilize any compounds for hormonal recovery, and the term post cycle therapy (PCT) did not even exist at that time. When the use of human chorionic gonadotropin (HCG) became increasingly popular (circa 1980), it was the only compound utilized. Since then, the medical and scientific understanding of such things has increased exponentially, and there should be no reason for any informed and adequately educated individual to utilize human chorionic gonadotropin (HCG) on its own for post cycle therapy (PCT). When used in conjunction with one of the other two categories of compounds (an AI and a SERM), the dynamics change considerably.

It has been mentioned already that much of the difficulty in recovering the Hypothalamic Pituitary Testicular Axis (HPTA) following an testosterone therapy is the result of Leydig cell desensitization. Human chorionic gonadotropin (HCG) is necessarily an analog of Luteinizing Hormone (LH), and the testes after a prolonged testosterone therapy would be as equally desensitized to human chorionic gonadotropin (HCG) as they are to Luteinizing Hormone (LH). The human body, however, produces Luteinizing Hormone (LH) amounts on its own that is far too inefficient for proper and rapid Testosterone production. The body’s natural increase of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH), evidenced by the study referenced earlier in which it was not until three weeks when Luteinizing Hormone (LH) levels only began to reach the standard physiological measurements following the cessation of Testosterone. Therefore, the body’s natural Luteinizing Hormone (LH) production does not provide a high enough dose for stimulation, nor an immediate stimulus to the tests required for the initial increase in Testosterone needed during the post cycle therapy weeks.

Human chorionic gonadotropin (HCG), utilized in a specific manner during the first 1 – 2 weeks of post cycle therapy (PCT) at a dose of 100-1,500IU every 2 days, is what allows the individual to provide the testes with a high dose to provide them with a ‘shock’ effect, and sustain this shock effect on the Leydig cells of the testes for a sustained period of the first 1 – 2 weeks of post cycle therapy. Studies have demonstrated the incredible effectiveness of human chorionic gonadotropin (HCG) for this purpose, it been suggested that human chorionic gonadotropin (HCG) therapy is utilized to treat low testosterone and hypogonadism. Following this line of thought, the other two compounds (the SERM and the AI) are to be used as supportive compounds for human chorionic gonadotropin (HCG) use in this 1 – 2 week period, and after human chorionic gonadotropin (HCG) is discontinued early on in post cycle therapy (PCT), only the SERM is to be used in order to carry along the hormonal recovery process.

In spite of the good news in regards to the ability for human chorionic gonadotropin (HCG) to assist in hormonal recovery, there are still two remaining issues to be addressed:

  • The fact that human chorionic gonadotropin (HCG) causes increased production of aromatase, leading to increased Estrogen levels.
  • Following the discontinuation of human chorionic gonadotropin (HCG), the body is left with very little endogenous Luteinizing Hormone (LH), and Follicle Stimulating Hormone (FSH) production due to the exogenous administration of human chorionic gonadotropin (HCG).

Aromatase Inhibitors:

Aromasin (Exemestane) Above All Else The first of the two remaining issues to be addressed will be the fact that human chorionic gonadotropin (HCG) will trigger increases in testicular aromatase expression, and result in Estrogen increases in the body. It should also be noted that it will cause an increase in testicular progesterone levels. Estrogen rising is, of course, undesirable during post cycle therapy (PCT), as it has already been explained that Estrogen will trigger suppression of endogenous Testosterone production, and there is no doubt that any individual wishes to encounter Estrogenic side effects during post cycle therapy (PCT) either.

Therefore, the option here is to include an aromatase inhibitor. However, there exists a big problem in regards to the other two of the three major aromatase inhibitors (Arimidex and Letrozole). The issue is the fact that in a post cycle therapy (PCT) program that includes the use of SERMs such as Nolvadex and Clomid, which are known as essential components to a post cycle therapy (PCT) program, Arimidex and Letrozole have direct negative interactions with Nolvadex. The problem here is that Arimidex (or Letrozole) and Nolvadex both directly counteract one another. One study has demonstrated that when Arimidex is utilized with Nolvadex, Nolvadex will decrease the blood plasma concentration of Arimidex (as well as Letrozole, another commonly used aromatase inhibitor). The conclusion here is that the use of Arimidex or Letrozole with Nolvadex together is a terrible idea and may work together in a post cycle therapy (PCT) protocol. Aromasin completely circumvents this problem, as it has been demonstrated to have no interactions what so ever with Nolvadex, unlike the other two aromatase above inhibitors. In one study, Aromasin displayed no such reduced effectiveness or any reduced blood plasma levels when utilized with Nolvadex.

The other benefit of selecting Aromasin over all other AIs is the fact that Aromasin has demonstrated in several studies to impact cholesterol profiles in a negative manner far less than other aromatase inhibitors have, wherein one particular review on cancer patients, 24 weeks of Aromasin (Exemestane) administration held no impact on cholesterol profiles. Some other studies have also demonstrated a nil effect on cholesterol profiles from the use of Aromasin. Although there have also been some studies that have shown a negative impact on cholesterol profiles resultant from Aromasin use, it is evident that there is not as a significant or as a negatively impacting effect from Aromasin on cholesterol as other aromatase inhibitor.

Finally, in addition to these benefits from Aromasin, it is evident that Aromasin holds the ability to increase Testosterone levels in males as demonstrated by studies. For example, one particularly notable study selected 12 healthy young male test subjects, and were administered random Aromasin doses of 25mg and 50mg for a 10 day period, and not only was Estrogen suppressed by a significant amount (38%), but Testosterone levels in the test subjects were observed to have increased by an incredible 60%.

Following these details, Aromasin would be the best possible aromatase inhibitor of choice to combat the increased aromatase activity caused by human chorionic gonadotropin (HCG). Therefore, Aromasin would then be utilized at a full 25mg daily dose, and only while human chorionic gonadotropin (HCG) is used. Once human chorionic gonadotropin (HCG) is discontinued, Aromasin too should be halted.

The only following issue to cover now is that of stimulating and maintaining proper endogenous Luteinizing Hormone (LH) release to carry recovery along until the body can become self-sufficient once again.

Nolvadex and Clomid: 

The question is often asked among the testosterone therapy using community: Clomid or Nolvadex? Which one for post cycle therapy (PCT)?

First of all, the best possible addition to human chorionic gonadotropin (HCG) in a post cycle therapy (PCT) protocol is Nolvadex (Tamoxifen Citrate), as studies have demonstrated that human chorionic gonadotropin (HCG) and Nolvadex utilized together have exhibited a remarkable synergistic effect in terms of stimulating endogenous Testosterone production and that Nolvadex will actually work to block the desensitization effect on the Leydig cells of the testes caused by high doses of human chorionic gonadotropin (HCG). This is very important because just as too little Luteinizing Hormone (LH) secretion for extended periods can cause desensitization to gonadotropins, too much gonadotropin stimulation (in the form of human chorionic gonadotropin (HCG) or otherwise) will likewise create a desensitization effect.

Secondly, Nolvadex on an mg for mg basis is far more effective than Clomid in stimulating endogenous Testosterone production, as well as being a more cost-effective choice than Clomid itself. Studies have demonstrated that 150mg of Clomid (Clomiphene Citrate) administered daily raised endogenous Testosterone levels of 10 healthy males by approximately 150%, while incidentally, 20mg of Nolvadex (Tamoxifen Citrate) daily raised endogenous Testosterone levels by the same amount. It is very evident here that Clomid is very useful for this purpose, but Nolvadex seems to be a more cost-effective choice seeing as though it is more effective than Clomid when compared mg for mg. The benefits of Nolvadex over Clomid do not end there – Clomid, although it does exhibit Estrogen antagonist effects at the pituitary gland as Nolvadex does, actually shows Estrogen agonist effects there too. What this means is that Clomid will work in varying degrees as an Estrogen at the pituitary gland, triggering the negative feedback loop and reducing the output of Testosterone stimulating gonadotropins Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH). This is a severe problem during post cycle therapy, which is a period in which individuals are trying to recover their Hypothalamic Pituitary Testicular Axis (HPTA) function rather than halt it even further. Ideally, one would want a SERM that exhibits almost 100% Estrogen antagonistic effects on the pituitary gland, and Nolvadex is the perfect choice for this.

When it comes to the dosing aspect of Nolvadex, The standard dose for post cycle therapy (PCT) and for stimulating the release of GnRH (Gonadotropin Releasing Hormone), Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH), and ultimately Testosterone is that of a single Nolvadex dose of 20 – 40mg daily. In all studies involving Nolvadex doses used to stimulate endogenous Testosterone production, only 20 – 40mg daily of Nolvadex was utilized, and it has been shown that doubling the dose to 40mg or any higher will not produce any significant difference in endogenous Testosterone secretion. The only reason why many elects to utilize 40mg daily of Nolvadex for the first 1-2 weeks of a post cycle therapy (PCT) program is to achieve optimal peak blood plasma levels quicker to ensure Hypothalamic Pituitary Testicular Axis (HPTA) recovery faster.

The ideal post cycle therapy protocol for 4 – 6 weeks Total post cycle therapy (PCT) time (depending on the recovery ability of the individual):

01) Weeks 1 – 2:

  • human chorionic gonadotropin at 1000iu/E2D.
  • Aromasin (Exemestane) at 25mg/day.
  • Nolvadex (Tamoxifen Citrate) at 40mg/day.

02) Weeks 2 – 6:

  • Nolvadex or (Tamoxifen Citrate).

Additional and Optional, Vitamins, Supplements, Compounds to Aid During post cycle therapy (PCT), Aside from the principal components discussed, various other parts are mostly optional, but still very useful for hormonal recovery of the Hypothalamic Pituitary Testicular Axis (HPTA) during the post cycle therapy weeks.

Vitamin B12 Health Benefits, There has been a lot of controversy over whether or not there is indeed a benefit from taking B12 supplements. Some doctors suggest that as long as a person is not vegan (though probiotics in the gut can produce some B12), they are probably getting sufficient B12 from the basic foods they are ingesting.

vitamin b12

Let us reference some studies:

There is documented research from the Framingham Study suggesting that 40% of all people are deficient in B12. The American Journal of Clinical Nutrition researched in 2009, and they published a study suggesting close to 6% of U.S. and U.K. residents over the age of 60 are B12 deficient. Another 20% were referenced as “marginal status.”

Vitamin B12 Health Benefits has the most multifaceted and prevalent chemical structure of all vitamins. One area where it differentiates from other vitamins is in the fact that it’s the only vitamin that contains a metal commonly referred to as Cobalamin, which is also a universal term for all the various compounds that may have some B12 properties in it.

B12 can improve energy by aiding in thyroid function and cellular methylation, That being said, B12 is not only useful in supporting healthy energy levels. It is unequivocally essential to life and whole existence. People deficient in B12 will suffer from serious health issues if the problem is not addressed.

What role B12 plays in the following human biological processes:

  • Nerve and brain regeneration
  • Adrenal gland support
  • Male and female reproductive health
  • Nutrient absorption
  • Red blood cell formation
  • Cellular energy
  • Memory recall
  • DNA synthesis

Here are some of the risks associated depleted B12 levels are:

  • Pernicious anemia
  • Migraine headaches
  • Macular degeneration
  • Tinnitus
  • Fatigue (adrenal fatigue and CFS)
  • Multiple sclerosis
  • Memory loss
  • Neuropathy
  • Anemia
  • Asthma
  • Shingles
  • Kidney disease
  • Depression

October 25, 2018 by Joseph Fermin 0 Comments

Male Menopause or Low-T is No longer Just for Older Men

Male Menopause or Low Testosterone, In our practice of low hormones, I’ve noticed that there is an increasing number of younger guys, as much as older men are complaining of sexual concerns and problems, like diminished libido and erectile difficulties.

Does some clinician believe that factors like obesity, stress and inadequate sleep probably play a role in such issues in the production of your hormones, and isn’t purely a lifestyle problem or question? These factors are also common or possible causes of low levels of testosterone, which can influence the role of sexual function problems.

book-free

Low Testosterone” is still most common in men over 30, also known male menopause or andropause, as you gradual testosterone decrease in testosterone typically occurs steadily over time. In fact, “after age 30, men experience a 3% reduction in testosterone every year,” the naturopathic doctor said. “According to Michael A. Werner, MD, a specialist in male infertility, erectile dysfunction and sexual dysfunction, male menopause or andropause occurs in 2% to 5% of men ages 40 to 49, rises to 6% to 30% in men ages 50 to 59, reaches 20% to 45% in men 60 to 69, and is found in up to 70% of men of ages 70 to 79 experience andropause with low testosterone.”

So that being said, low testosterone isn’t necessarily just a consequence of aging. Some factors can have an impact on a man’s testosterone levels. Low Testosterone has many factors influence sexual health, including mood, energy level, nutrition, genetics, age, health conditions, and medications, and more commonly seen in older men or such as:

Motivation: As testosterone production declines so do energy-boosting components and restful sleep, thus producing decreased motivation.

libido: Low levels of testosterone cause a reduction in sex drive.

Depression: When a person experiences low testosterone levels it alters hormone production, which can lead to depression.

Erectile Dysfunction: Testosterone supplementation can be used to reverse or correct low testosterone-induced erectile dysfunction.

Fatigue: A decrease in testosterone levels leads to hormonal changes, which can cause fatigue, also can be exacerbated by low testosterone-induced sleep loss, which can quickly turn into a vicious cycle.

High Cholesterol: High cholesterol is a silent killer that can lead to a variety of heart conditions. Testosterone injections, when used in a proper protocol, can lower cholesterol, blood pressure, and triglyceride levels.

Low Energy & Fatigue: Symptoms of aging can be a direct result of diminishing levels of testosterone or (Low-T) in the body. As we age, our bodies produce less and less testosterone, causing low energy and fatigue.

Memory Loss: Some recent evidence suggests that testosterone might help prevent and treat the effects of brain aging. Some patients treated with testosterone injections expressed a palpable increase in their cognitive function, short- and long-term memory, and vocabulary improvements.

Thyroid: The hormones produced by the thyroid and adrenal glands regulate vital processes throughout the body. If thyroid hormone and cortisol levels are abnormal, the rest of the body does not function properly. Some studies have suggested a link between low thyroid function and low testosterone levels.

Weight Gain: The production of certain hormones decreases after the age of 30. The lean body mass of some organs also starts to decline, whereas fat mass increases. Testosterone administration can affect your body composition.

One option for low testosterone is prescription is testosterone replacement therapy (TRT), “Testosterone, like all hormones, has multiple actions on many body functions and the mind,” that being said.

“In my opinion, it should be taken — and prescribed — only to correct a deficiency documented by appropriate blood tests.” Otherwise, We recommend “an integrative approach to sexual health” that assesses all the many factors that affect testosterone.

July 31, 2018 by Joseph Fermin 0 Comments

The 6 Effects of Testosterone in Your Body

The 6 Effects of Testosterone in Your Body

6 Effects of Testosterone in Your Body, However, the body changes as we age and loses some of its regenerative capacity. A fundamental part of this decline roots from a slow-down in our hormonal secretions. Simply put, even young people with glandular issues who do not produce enough testosterone and/or HGH experience side effects and maladies that are usually only associated with much older individuals. Conversely, older patients with higher hormone levels, be it naturally or via hormone replacement therapy, have health benefits normally associated with younger individuals.

Also, Women’s Can Be at Risk for Low Testosterone:

The ovaries are responsible for producing both testosterone and estrogen, as the ovaries age, they produce less estrogen and testosterone. As women enter peri-menopause and pre-menopause, testosterone will be diminished by the age of 30’s, and once a women reach full menopause, it’s common for them to produce 75% less testosterone than they did in the there 21’s. Every woman becomes at risk of low testosterone as she ages, and women who go through hysterectomy or oophorectomy have an even higher chance of dealing or having low testosterone in women levels.

6 Effects of Testosterone in Your Body.

  • Changes the Brain:

Research has shown that women have a significant advantage when it comes to a few things, Like memory and language, while men tend to have stronger spatial skills (though this too has been disputed). But due to ethical restrictions, no study had been able to track the direct effect that testosterone exposure has on the brain—until now.

The hormone also plays a role in your state of mind, including how well your brain works. That’s why low testosterone has linked to symptoms such as mood swings, increased stress, and depression. … “Cells in the brain have testosterone receptors, and low testosterone in those receptors are significantly affected mental health.”

  • Muscle and Strength:

Recent studies have shown that men as they age, they lose more muscle mass than women of the same period, and has led researchers to believe that the loss of muscle strength and has it has a direct link to the predominantly male decline hormone, like testosterone. Testosterone helps to build muscle mass and strength in young men.

Testosterone supplementation in men increases fat-free mass, but whether measures of muscle performance, such as maximal voluntary strength, power, fatigability, or specific tension, are improved has not been determined. … A seated leg press exercise defined maximal voluntary muscle strength and fatigability.

  • Bone Density and Osteoporosis:

As men age, their serum testosterone concentrations decrease, as do their bone densities. Because bone density is also low in hypogonadal men, we hypothesized that increasing the serum testosterone concentrations of men over 65 yr to those found in young men would raise their bone densities.

Testosterone increases levels of growth hormone. That makes the exercise more likely to build muscle. Testosterone increases bone density and tells the bone marrow to manufacture red blood cells. … Dropping the levels of testosterone can cause an increase in body fat.

  • Sex Drive and Libido:

Some men maintain sexual desire at relatively to low testosterone level. For other men, libido may lag even with normal testosterone levels and low testosterone is one of the possible causes of low desire and sex drive, however. If testosterone has lowered far enough, virtually all men will experience some decline in sex drive.

Growth hormone (GH) has also been used to reverse or correct erectile dysfunction and other sexually impeding disorders and the primarily by improving circulation and blood flow, which results in a firmer, more sustainable erection.

  • Bone Marrow and Red Blood Cells:

Erythropoiesis affects the production of new red blood cells. One is accomplished primarily in the bone marrow, the red blood cell factory. Erythropoiesis is stimulated mainly by erythropoietin (hence, the clever naming of that hormone!). … Androgens, including testosterone, are another type of hormone.

Testosterone and other androgens have an erythropoietic stimulating effect that can cause polycythemia, which manifests as an increase in hemoglobin, hematocrit, or red blood cell count. … If hematocrit elevated before starting testosterone, the cause should determine before beginning androgen therapy

  • Skin and Collagen:

A man or women with shrinking levels of testosterone actually may lose some body hair. Testosterone replacement therapy comes with a few potential side effects, including acne and breast enlargement. Testosterone patches may cause minor skin irritation.

In fact, research now suggests that bioidentical hormone replacement therapy (or BHRT) can actually reverse many of the signs of aging and that you may have come to accept – weight gain, low libido, reduced muscle mass – and can even help to prevent conditions such as osteoporosis, heart disease, and dementia.

 

(more…)

February 10, 2018 by Joseph Fermin 0 Comments

The Facts about Testosterone and Andropause

Testosterone and Andropause

AndropauseTestosterone and Andropause: Testosterone is the primary hormone responsible for deep voices, muscle mass, sex drive, are some of the patterns found in males. As men age and get older, the level of testosterone in the body and production of sperm gradually becomes lower, and they experience physical and psychological symptoms as a result of these low levels of testosterone and is the part of the natural aging process.

Andropause is a condition that is symptoms of the decrease in the male hormone testosterone. Approximately 80% of men in their 50s will experience symptoms of andropause caused by low testosterone levels. A person suffering andropause may have some symptoms related to the condition and could be at risk of other severe health conditions.

Causes of Testosterone and Andropause:

The decrease in testosterone is an essential factor in men having andropause problems. As men age, the body starts making less testosterone, and also the levels of other hormones like (SHBG) “Sex Hormone Binding Globulin,” which pulls usable testosterone from the blood, begins to increase. (SHBG) Also Binds some available testosterone circulating in the bloodstream. The testosterone that is available and not linked to the SHBG hormone described as bioavailable testosterone.

Men who experience symptoms associated with andropause and low testosterone have lowered amounts of bioavailable testosterone in their bloodstream. Therefore, The tissues in the body which are stimulated by testosterone receiving a smaller number of it, which may cause physical and possibly mental changes in a person such as mood swings or fatigue and more.

Complications and Symptoms of Testosterone and Andropause:

  • Thyroid
  • Cellulite
  • Decrease Motivation
  • Sex Drive and Desire
  • Lack of Energy
  • Depression
  • Irritability and Mood Swings
  • Loss of Muscle Mass
  • Memory Loss
  • Hot Flashes
  • High Cholesterol
  • Hair Loss
  • Sleep Disturbance
  • Slow Recovery From Wounds Healing and Illness

Complications associated with andropause include an increased risk of cardiovascular problems and osteoporosis (brittle bones) and more.

Treatment and Prevention of Testosterone and Andropause

Testosterone Injections is the most common treatment for men going through andropause. This therapy may provide help and relief from the symptoms and help improve the quality of life in many cases, also lifestyle changes such as increased exercise, stress reduction, and proper nutrition also help.

Testosterone therapy is available in different forms, ask your doctor he will help determine which treatment is best for you.

testosterone-injections

 

Testosterone Injections is the most common treatment for men going through andropause. This therapy may provide help and relief from the symptoms and help improve the quality of life in many cases, also lifestyle changes such as increased exercise, stress reduction, and proper nutrition also help.

Testosterone therapy is available in different forms, ask your doctor he will help determine which treatment is best for you.

TESTOSTERONE INJECTIONS: This treatment involves doses of bioidentical (Testosterone Cypionate, Testosterone Enanthate, and Testosterone Propionate).

TESTOSTERONE PATCHES: People who wear a piece containing testosterone receive the hormone through the skin. The patches allow a slow, steady release of testosterone into the bloodstream.

TESTOSTERONE GEL: This treatment is also applied directly to the skin, usually on the arms. Because the gel may transfer to other individuals through skin contact, a person must take care to wash the gel from the hands after each application.

TESTOSTERONE CAPSULES: This is yet another option for testosterone replacement. Men with liver disease, poor liver function, severe heart or kidney disease, or too much calcium in their blood should avoid testosterone capsules.

Follow-up visits with your doctor will be necessary after the initial treatment begins. At follow-up visits, your doctor will check your response to the treatment and make adjustments, if necessary.

Anybody with prostate or breast cancer should not take testosterone therapy. If you have heart disease, liver disease, enlarged prostate, or have kidney, contact your physician whether or not treatment is right for you.

December 20, 2017 by Joseph Fermin 0 Comments

How Testosterone Affects Fat Loss: Real Science of Low-T

How Testosterone Affects Fat Loss: Real Science of Low-T

Testosterone Affects Fat Loss, As men age, their testosterone levels decline. This increase in SHBG (sex-hormone binding globulin), which binds to testosterone and thus reduces the amount of free testosterone in the body. Low testosterone levels, obesity, and many other health problems, including fatigue, memory problems and decreased muscle and bone mass. So what is the impact of testosterone on the body and how Testosterone Affects Fat Loss?

Testosterone and energy – low levels of testosterone can cause low energy levels. Regaining natural testosterone levels can increase strength and lead to weight loss. Studies have found that testosterone supplementation reduces total body fat percentages. Obesity is related to low testosterone levels in men. Just as testosterone therapy is associated with decreased obesity, losing weight is associated with increased testosterone levels.

An article in 2014 in the journal of Current Opinion in Endocrinology, Diabetes, and Obesity looked at the existing data regarding testosterone therapy in overweight and obese men with testosterone deficiency (hypogonadism).

  • Many weight loss supplements have dangerous side effects or are ineffective
  • Looked at weight loss, BMI, waist circumference and body composition
  • Evaluated long-term testosterone therapy
  • About 40% of obese nondiabetic men and 50% of overweight diabetic men over 45 have low levels of free testosterone
  • Many studies have found that testosterone therapy in overweight men helps increased lean body mass, weight loss, decreased BMI and reduced waist circumference.
  • Weight loss is significant and sustained with long-term testosterone therapy
  • Testosterone plays a part in protein, fat and carbohydrate metabolism.
  • Testosterone is involved in mitochondrial function and thus energy production and utilization
  • This interference with energy production is likely why those with low testosterone levels experience a lack of energy
  • Testosterone therapy has been found to increase lipid oxidation and normalize glucose use in the body. It was found to increase strength and motivation.

Weight gain associated with an 88% increase in body fat and a 12% increase in lean body mass (LBM) and weight loss with a 72% decrease in body fat and a 28% decrease in LBM.

  • With testosterone therapy, LBM has been shown to increase.
  • Increased LBM means increased energy expenditure at rest
  • Testosterone therapy with improved cardiometabolic function

Testosterone deficiency decrease in energy metabolism from fat and an increase in energy metabolism from glucose.

  • Testosterone therapy has been shown to increase lipid metabolism

Safety? Safety is the primary concern with testosterone replacement therapy. Possible risks discussed in the literature include:

  • Increased risk of prostate and breast cancer
  • Liver toxicity and tumors
  • Sleep apnea exacerbation
  • Testicular infertility and atrophy

Talking with your doctor before starting testosterone injections therapy is necessary.

Summary: If you are a male struggling to lose weight, testosterone therapy is a promising treatment to help with not only weight loss but for body composition, energy levels and overall health.

November 13, 2017 by Joseph Fermin 0 Comments

An Inside Look at Testosterone Injections Therapy

Inside Look Testosterone Injections Therapy

testosterone injections therapyTESTOSTERONE INJECTIONS THERAPY

Testosterone is an essential factor in males, that does more for men than just promote sex drive. Low Testosterone levels decline as a part of healthy aging and are the cause of several physiological changes. Low Testosterone level symptoms include;

1) Reduced Motivation
2) Erectile Dysfunction
3) Loss of Libido or sex drive
4) Fatigue and low energy
5) Increased Cholesterol Levels
6) Memory and Concentration
7) Decreased Muscle Mass
8) Thyroid Dysfunction and more

Since these symptoms are common in low testosterone, physicians will often include hormone levels as part of routine blood work. Normal levels of testosterone are between 300 and 1,000 ng/dL. If a blood test shows that your levels are far below the norm, your doctor may suggest testosterone injections. The treatment is called TRT.

SYMPTOMS OF LOW TESTOSTERONE

Most men naturally start losing testosterone when they hit their 30’s. (low T). Common symptoms of low Testosterone include:

1) Erectile dysfunction (ED)
2) Changes in sex drive
3) Decreased sperm count
4) Depression or anxiety
5) Weight gain
6) Hot flashes

TESTOSTERONE AND DIAGNOSIS

Many men may want to diagnose themselves with a testosterone kit. The problem with self-diagnosis is that many of the symptoms of low Testosterone are healthy parts of aging. So using it for diagnosis isn’t reliable. Our doctor may order testosterone blood test. It is the only way to find out if you have low testosterone.

To get a perfect reading our doctor will take a look at your health history, physical exam and blood test to measure your testosterone levels. You’ll also likely have a test that measures your red blood cell count.

POTENTIAL BENEFITS OF TESTOSTERONE INJECTIONS THERAPY 

The purpose of Testosterone Injections Therapy is to help regulate hormone levels and to help address problems related to low Testosterone. For men with low Testosterone, the benefits of these injections can include:

1)  Motivation and Memory Loss
2)  Sex Drive & Desire
3)  Depression and Energy
4)  Cholesterol and Osteoporosis
5)  Erectile Dysfunction
6)  Muscle Mass and Better Sleep
7)  Wounds healing & Illness
8)  Thyroid Dysfunction and more

TESTOSTERONE CAN HELP WITH FAT AND MUSCLE CHANGES

Men have less body fat than women; This is partly related to testosterone, which regulates the fat in the body and muscle maintenance in your body. You’ll likely also notice an increase in body fat, especially around your midsection.

Your hormones also help regulate muscle growth. So, with low Testosterone, you may feel like you’re losing muscle size or strength.

Testosterone shots regulate fat distribution, but you shouldn’t expect significant weight loss changes from hormone therapy alone, without exercise. As for maintenance of muscle, testosterone therapy has been found to improve increase muscle mass, but not strength.

TESTOSTERONE INJECTIONS THERAPY AND SPERM COUNT

Low sperm count in men is a common side effect of low Testosterone. This problem can make it difficult to get your partner pregnant.

TESTOSTERONE INJECTIONS THERAPY AND THE BOTTOM LINE

Testosterone injections therapy can only be helpful If you just have low Testosterone. If you’re wondering if testosterone is a right choice for you, ask your doctor. They can test you for low Testosterone. Ask your doctors, or Give us a call, if testosterone injections therapy would be a good choice for you.

If you don’t end up having low Testosterone but still feel like your hormone levels might be off, keep in mind that proper Food, Regular exercise, could help you increase testosterone naturally and make you feel better. If that doesn’t help, be sure you contact us for help.

October 26, 2017 by Joseph Fermin 0 Comments

Testosterone Therapy’s and The answer for Aging Men?

Testosterone Therapy’s and The answers for Aging Men

testosterone therapy's

Testosterone therapy’s, It’s a fact of life – as men age, the level of testosterone in their bodies decreases. But, is an Injectable replacement therapy is a right solution for you for many people? Testosterone therapy has possibilities of:

1) Improve muscle & bone loss
2) Improve memory & mental focus
3) Boost your libido
4) Improve energy level overall
5) Restore sexual function and muscle strength

Testosterone Injectable therapy has been used successfully for years for treating men with abnormally low testosterone levels – a medical condition called hypogonadism.

The decline of testosterone Starting around age 30 to 40, in man’s body, produces less testosterone. Testosterone is the primary male hormone it maintains: fat distribution, muscle mass, strength, bone mass, sperm production, sex drive, and potency.

Low testosterone can have several effects on the body, including:

1) Decreased energy
2) Reduced muscle mass and strength
3) Cognitive function
4) Less sexual interest or potency
5) Depressed
6) and much, much more.

If you experience these symptoms, you may have low testosterone. Also, some healthy men encounter these changes as a part of the aging process, possibly because of declining hormones other than testosterone.

Next, contact AAI Rejuvenation Clinic physician’s to learn more about Testosterone injectable Therapy. He or she can help determine the likely cause and suggest the best treatment plan if any.

Also, some healthy men encounter these changes as a part of the aging process, possibly because of declining hormones other than testosterone.

Why should take testosterone therapy?

Testosterone therapy is beneficial for men who fail to produce sufficient levels of testosterone (male hypogonadism).

 

July 17, 2017 by Joseph Fermin 1 Comment

All You Need to Know About Testosterone Benefits

What You Need to Know About Testosterone Benefits

Right around the age of 30, most men experience a significant “shift” in their lives. They can’t tell what it is. They can’t quite put their finger on it. All they know is, something has “changed”. Usually, men attribute it to being “tired” from working so hard, keeping up with the kids and maintaining their household. The supposition is, “if I can only get one good nights rest, I’ll be all better the next day,” but that day never comes. (*) Individual Results May Vary & Are Not Guaranteed

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