What is the Peri-menopause?
As women, our bodies undergo dramatic changes as we age, and our hormones cause these changes. Peri-menopause is the time of a woman’s life when her hormonal cycle slows, her fertility reduces, and periods become less common as she heads toward menopause. It can be very stressful because it affects her physical and emotional state.
It understands what causes peri-menopause and how to reduce the symptoms best. It is essential to appreciate the changes in the female body during aging. There are four main stages in a woman’s hormonal life:
Puberty is the process of sexual maturation; it typically begins around the age of 11 and lasts for several years. Generally, it starts with breast development, followed by the growth of pubic hair, and finally, menstruation.
The Reproductive Years
The reproductive years begin with the onset of menstruation and persist until peri-menopause. They are characterized by the menstrual cycle, which controls a woman’s fertility. The menstrual cycle is primarily governed by fluctuations in the levels of the hormones that prevent ovulation and regulate the thickness of the uterine lining to prepare for the implantation of a possible fertilized egg.
- The hypothalamus secretes gonadotropin hormone-releasing hormone (GnRH), which stimulates the pituitary gland to release follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
- FSH stimulates follicles in the ovaries to prepare an egg for maturation and release, which includes the secretion of estrogen to prepare the uterus for implantation.
- LH triggers ovulation, or the release of an egg from the ovaries, which produces and releases progesterone and additional estrogen to prepare the body for fertilization and pregnancy .
Peri-menopause occurs when a woman’s hormonal cycle transitions toward menopause and infertility begin. It often starts in women in their late40s and lasts up to 11 years; the average duration is ~4 years. During peri-menopause, menses become less common, and the symptoms typically associated with menopause (discussed below) begin. Altered hormone levels cause the changes that occur during menopause. A woman remains fertile only as long as her ovaries produce and secrete eggs via a process known as ovulation. Since there are a finite number of eggs, female fertility has an expiration date.
The production of estrogen and progesterone relies upon ovulation, which means that hormone production is diminished significantly once eggs are no longer released. Hormonally, peri-menopause is defined by persistently increased LH and FSH levels and deficient estrogen and progesterone levels. Testosterone secretion can also decline by approximately 50% during peri-menopause .
Menopause officially starts one year after a woman’s last period. Menopausal women produce very high levels of FSH but low levels of estrogen and progesterone. They are no longer fertile and are at a higher risk of osteoporosis and cardiovascular disease because of the reduced hormone concentrations .
What are the Symptoms of Peri-Menopause?
- Hot flashes
- Reduced sex drive
- Discomfort and dryness during sex
- Problems sleeping
- Mood swings
- Severe premenstrual syndrome
- Irregular periods
- Breast tenderness
- An urgent need to urinate
- Urine leakage, particularly when sneezing or coughing
Because other hormone-related conditions can cause some of these symptoms, we always recommend checking your hormone levels to ensure you receive an accurate diagnosis.
This will allow us to develop a program to make you feel like your old self.
Alleviate Your Symptoms with Hormone-Replacement Therapy (HRT)
For many years, HRT alleviated peri-menopause symptoms and reduced the risk of mortality, dementia, cardiovascular disease, and osteoporosis in aging women.
Although a now-revised link to an increased risk of breast cancer led to a temporary decline in the use of HRT, it is again the number one treatment and disease-prevention strategy used in peri-menopausal and menopausal women .
As the name suggests, HRT aims to replace the hormones that are no longer being produced naturally. The hormones are often delivered in tablet form, although transdermal Testosterone Patches, creams, Testosterone Gels, and implants can also be used.
There are four significant forms of HRT:
- Estrogen alone
- Estrogen and progesterone
- Gonadomimetics, which contains estrogen, progesterone, and testosterone; an example is a tibolone
- SERMs (selective estrogen receptor modulators)
Because HRT can restore your hormone levels to those you experienced when you were young, it can relieve your symptoms and reduce the risk of diseases associated with low hormone levels, such as osteoporosis and cardiovascular disease. Although some studies have suggested that HRT could protect against stroke, diabetes, cognitive aging, and mood, these effects are more controversial .
HRT reduces the risk of cardiovascular diseases.
An evidence-based study investigated the evidence from randomized clinical trials. It concluded that HRT could reduce the risk of mortality and cardiovascular disease in women within ten years of menopause aged <60 years . However, there is evidence that HRT should be avoided in older women because it might increase the risk of coronary events .
HRT reduces the risk of osteoporosis.
One of the best-known benefits of HRT is its ability to inhibit bone loss and reduce the incidence of fractures in peri-menopausal women; estrogen therapy might be more effective than combined estrogen-progesterone treatment .
In addition to these clinical effects, HRT alleviates peri-menopause symptoms, including skin and hair complaints and sexual symptoms , and hot flashes . Measure your hormone levels today and determine if HRT could improve your daily life.
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-  The 2012 hormone therapy position statement of The North American Menopause Society, Menopause (New York, N.Y.), 19 (2012) 257-271.
-  D. Rouskova, K. Mittmann, U. Schumacher, H. Dietrich, T. Zimmermann, Effectiveness, tolerability and acceptance of an oral estradiol/levonorgestrel formulation for the treatment of menopausal complaints: a non-interventional observational study over six cycles of 28 days, Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology, 30 (2014) 712-716.
-  N. Santoro, C.N. Epperson, S.B. Mathews, Menopausal Symptoms and Their Management, Endocrinology, and Metabolism clinics of North America, 44 (2015) 497-515.
**NOTE** The content in this blog is subject to interpretation and is the opinion of the content writer. We do not claim it to be fact. We encourage you to consult a medical doctor before taking any prescribed medications or supplements.
Supporting Hormones health is essential for overall well-being and vitality. By incorporating regular exercise, proper nutrition, adequate sleep, stress management techniques, and IV therapy, you can help maintain optimal testosterone levels and lead a healthy, balanced life. Always consult a healthcare professional before making significant changes to your lifestyle or starting any new treatments to ensure they suit your needs.
At AAI Rejuvenation Clinic, we advise anyone to think seriously about beginning Hormone treatment if there is no medical need. However, we will take every precaution to ensure that you read your program’s positive benefits by providing the latest at-home hormonal mouth-swab testing to ensure we are continually monitoring your progress and aware of any adverse side effects. Fill out the Medical History Form, or if you need more information, call us at (866) 224-5698 or (866) AAI-Low-T.
Low Hormone Symptoms
- Sex Drive and Desire
- Erectile Dysfunction
- Low Energy
- Memory Loss
- Wounds & Illness
- Muscle Mass
- Sleep Disturbances
- Thyroid Dysfunction
- Weight Gain