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Category: Vitamins

March 4, 2019 by Joseph Fermin 0 Comments

What is Luteinizing Hormone (LH) and Testosterone

What is Luteinizing Hormone &
The Productions of Testosterone

If you google the word Luteinizing Hormone or (LH), most of the articles you will find talks about the role of luteinizing hormone in women. There is very no info about the part of Luteinizing Hormone in men. While it may seem like a female hormone due to its role in ovulation, a surge of Luteinizing Hormone is a trigger that causes the ovary to release the egg, in the body. If you’ve been trying to conceive or have a baby your wife, significant other may be monitoring her Luteinizing Hormone levels. If she has trouble with ovulation, your doctor may prescribe medications that help with ovulation.

Many of this medication help stimulate the body to produce more Luteinizing Hormone (LH) and its cousin hormone, Stimulating Follicle Hormone (FSH). If you are not trying to conceive, or get pregnant, she may be on hormonal birth control pills. These pills prevent ovulation by blocking Stimulating Follicle Hormone and Luteinizing Hormone. It is one of the manliest hormones in your body. You can think of Luteinizing Hormone as a tiny drill sergeant that commands the Leydig Cells in the testicle to produce testosterone. When Luteinizing Hormone is present, the Leydig Cells generate Testosterone, when it is not, they don’t. Luteinizing Hormone is commander and chief of your Testosterone and critically crucial for sperm production count, muscle building, and overall sexual health.

Male hormones have a clinical nature to them. Luteinizing Hormone (LH) signals the testicle to produce Testosterone. Testosterone seeps out of the testis and into the bloodstream, where it circulates the body and put to good use. Manly things like growing chest hair, increase muscle and your voice deep are some of the effects.

Luteinizing Hormone or (LH)

The brain monitors the blood testosterone levels;

  • If they drop too low, it will send a signal to the pituitary gland to send out more Luteinizing Hormone (LH) to kick start testosterone production.
  • If your testosterone is chronically low (as in the case with hypogonadism or Low Testosterone), the brain will respond by increasing the level of Luteinizing Hormone (LH).
  • If testosterone is chronically higher (as in the case with using testosterone therapy, other performance enhancers or steroids), the brain will shut down production of Luteinizing Hormone (LH). When testosterone therapy is stopped, without post-therapy, men can experience a “crash” as Testosterone levels plummet, but with a post-therapy, the brain lags in re-starting the machinery to generate Luteinizing Hormone.

Getting Tested:

To measure Luteinizing Hormone (LH) levels, you will need to get blood work in a hormone clinic done. Because, doctors will order blood to estimate a panel of hormones which usually includes Stimulating Follicle Hormone, Luteinizing Hormone, Testosterone, Estrogen and They may also add Estrodial, Prolactin which will provide additional information into the insight into your hormonal health and a physical to know your body composition.

In a typical day, Luteinizing Hormone (LH) and Testosterone levels cycle from high to low. When getting blood work done to measure hormone levels, it is important to note the time of day that the analysis was performed to understand the values better.

Testosterone naturally will peak first thing in the morning (partially responsible for morning “wood”). For this reason, doctors prefer to regulate hormones between 8-10am to get a snapshot of your hormone panel profile when Testosterone level is likely to be highest.

When preparing for a Luteinizing Hormone test and to sure your doctor is aware of a few things like:

  • Current Prescription Taking: Current or past use of testosterone therapy. (If you are using anything at the gym or in supplements stores and you aren’t quite sure), you should bring it with your doctor about the appointment.
  • The Use Of Marijuana or THC: It may decrease the number of hormones levels, including Luteinizing Hormone.
  • Medical Radioactive Tracer: This can interfere with the test
  • Normal levels Luteinizing Hormone Range For Adult Males: 1–10 mIU/mL.

They are different labs report different reference ranges, and based on the exact way that they perform the blood work test. From a review of various lab reports, Values lower than 1.0 or higher than 10.0 typically indicate some problem.

For average men, Luteinizing Hormone (LH) typically falls somewhere between 4-7mIU/mL with drops and surges (about 6) throughout the day. Values below 4 and above seven may be considered borderline, and are useful to look at when compared to other hormones, particularly Testosterone and Prolactin.

In the studies that we have reviewed and found that these types of conditions have shown, and can significant drops in testosterone levels and minimal effect in Luteinizing Hormone (LH). Occasionally, Luteinizing Hormone may show up a little low, but often it is entirely in the normal range.

Therefore, low testosterone levels accompanied with normal Luteinizing Hormone (LH) levels often indicate the cause of Low Testosterone can tremendously help to diagnose the condition and also help to create a game plan for treating the cause while managing symptoms of low Testosterone.untitled-design-16

Whats the Causes of high Luteinizing Hormone in Men?

If Luteinizing Hormone (LH) is high and testosterone is low. Then some damage is causing the testicle, or the pituitary gland is trying to compensate by going into overdrive and flooding the balls. With extra Luteinizing Hormone in hopes that it will encourage higher Testosterone production. In cases like this, Luteinizing Hormone levels are often off the charts high sometimes double or triple the average values.

Common causes for this include:

  • Chromosome Abnormalities: Such as Klinefelter’s syndrome
  • Childhood Problems: Such as testicle or testicular torsion, The injury that causes significant damage to testicular tissue
  • Viral Infection: (most commonly mumps) that damages the testis.
  • Radiation exposure or chemotherapy
  • Testicular cancer
  • Borderline High Luteinizing Hormone (LH) levels

Medications or untreated autoimmune disorders can cause slightly elevated Luteinizing Hormone (LH) levels (8.0 – 10.0 range). Some studies have linked Celiac’s Disease with elevated somewhat Luteinizing Hormone (LH). Men with the untreated disease can have moderately high Luteinizing Hormone levels, that usually return to normal upon starting a gluten-free diet.

What causes low Luteinizing Hormone in Men?

The most common reason for Luteinizing Hormone deficiency in men is the use of external androgens (testosterone, other performance enhancers or non-medication). External androgens can trick the brain into thinking the body is producing naturally high levels of testosterone which low down production of luteinizing hormone (LH) and consequently natural testosterone production.

The second most common cause of low Luteinizing Hormone (LH) levels is a health issue, and can directly impact the function of the pituitary in the brain, Most common causes of the pituitary malfunction can include genetic conditions, such as Prader-Willi Syndrome or Kallman’s Syndrome and can cause other problems like:

  • Pituitary tumors (cancerous and benign)
  • Hyperprolactinemia
  • Head trauma
  • Various Medications
  • Auto-immune disorders
  • Borderline low Luteinizing Hormone (LH) results

Luteinizing Hormone levels in the 1.0 – some things can cause 3.0 range. Like, reduce temporarily imbalance hormones: such as overtraining, endurance. They are significantly under or overweight Alcohol consumption spikes in insulin medications or other drugs. High-stress Chronic conditions: that can cause hormone imbalance: such as diabetes, insulin resistance, various auto-immune disorders and can create borderline or low levels of Luteinizing Hormone (LH).

 

January 28, 2019 by Joseph Fermin 0 Comments

The importance of Testosterone Post Cycle Therapy?

Why Is Testosterone
Post Cycle Therapy Is Need It?

Why is Post Cycle Therapy (PCT) is perhaps the most critical aspect of testosterone use? The concept of the post cycle therapy (PCT), did not exist before the late 1980s, and 1990s and the mechanisms by which testosterone affected, the body were not wholly understood during the 1950s, 1960s, and 1970s.

This period were doctors, scientists, and testosterone injections users were only beginning to learn about the dynamics of testosterone and how they affect the endocrine system. We believed and understood since the beginning of testosterone injections use, the administration of testosterone resulted in triggering the body’s negative loop of the (HPTA) Hypothalamic Pituitary Testicular Axis. That endogenous Testosterone production would result become suppressed and shut down. The, unfortunately, is during the early periods of testosterone use between the 1950s and 1990, there was limited access to the compounds or knowledge or effectively.

Today it is a very different story. Now scientific and medical understanding of bio-identical testosterone use has soared exponentially since the old ‘golden era’ days of looking young and testosterone therapy use in athletics. Countless developments of beneficial compounds for hormonal recovery after testosterone therapy use, alongside the increased scientific and medical knowledge, has enabled testosterone use and its associated endocrine disruptions. The proper knowledge on how to recover the body’s from Hypothalamic Pituitary Testicular Axis (HPTA). Through post cycle therapy (PCT), we can not only emerge from their testosterone therapy while holding on to almost all of their benefits, but they can also increase the chances upwards to 90 percent or higher range of emerging with a fully healthy (HPTA).

Following the use of exogenous testosterone injections, the majority of users will experience what has been a hormonal crash or post cycle therapy crash, which is a physical environment in which key hormones essential is has been suppressed or shut down. The critical hormones in question are Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH), and subsequently (and are most importantly), for our natural testosterone. The Luteinizing Hormone (LH), and the Follicle Stimulating Hormone (FSH), known as phototropism. These hormones increase Testosterone secretion. Also alongside low levels of these hormones, to balance the essential hormones that have been thrown off balance, whereby Testosterone levels will be small, and most of the time, depending on the factors, estrogen levels will be higher than usual, and levels of Cortisol a steroid hormone that destroys muscle tissue. With the testosterone levels low and Cortisol levels in the average or high, Cortisol now can become a threat to the new muscle during the new testosterone therapy (“Testosterone correctly suppresses and counteracts Cortisol’s catabolic effects on muscle tissue”). The SHBG (Sex Hormone Binding Globulin) is also a concern here as well, which is a protein that binds to sex hormones Testosterone renders them inactive, essentially ‘handcuffing’ them and preventing them from exerting their effects. SHBG will also usually elevated during the post cycle therapy weeks as a result of the supraphysiological levels of androgens from the new testosterone therapy.

The human body will generally and restore this imbalance of hormones and recover from testosterone levels on its own, over time with no outside assistance or post cycle therapy (PCT), but the studies have demonstrated and shown us that without the intervention of testosterone stimulating agents, this will occur throughout one to four months. Therefore, all testosterone therapy should be concerned with the fastest possible hormonal recovery, assisted and boosted with the use of Testosterone stimulating compounds correctly, also the attempt to allow the body to recover on its own, from a very high probability of long-term endocrine damage to the Hypothalamic Pituitary Testicular Axis (HPTA), whereby the individual will develop-induced hypogonadism to inability the production of proper levels of Testosterone to rest. So therefore paramount that an appropriate post cycle therapy that includes multiple recovery compounds to be utilized to not only restore the (HPTA) function but also to normalize the levels as quickly as possible. To avoid any possible permanent damage, which can take priority over the concern of maintain to the recently gained muscle mass and any other benefits from it.

What Post Cycle Therapy Protocol?

There are many different types of post cycle therapy (PCT) protocols that have overdeveloped over the years; any individual will become extremely confused about how many different opinions exist among the testosterone community, This article will present the best possible and most efficient post cycle therapy protocol valid scientific data, also myths in regards to post cycle therapy (PCT), and outline which post cycle therapy (PCT) protocols should not follow due to recent more advanced developments, as well as contemporary better scientific and medical understandings of how a proper post cycle therapy protocol should work. This point, there still exists very obsolete – and subsequently ineffective – post cycle therapy (PCT) contracts that are still utilized by many testosterone users, and this presents a severe hazard not only for the individual unknowingly using a post cycle therapy.

For example:

There are several therapeutic and safety reasons why you should not continue with testosterone injections indefinitely without giving your body time to normalize to reset. Because of the decline in benefits after six months of a testosterone therapy, the physicians need to regularly incorporate a cleanse therapy post cycle therapy (PCT) in an attempt to reactivate the endocrine in the body, as you increase your testosterone levels using any testosterone therapy, now the levels of testosterone circulating the body will shut down the natural production of your endogenous testosterone; and also increases the production of estrogen in your body, which can lead to a series of undesirable and unwanted side effects in the body. `This means that the synthesis of (LH) luteinizing hormone in your body; this hormone is produced by your brain to stimulate testosterone production. and follicle-stimulating hormone in the body; the hormone produced by your mind to boost sperm production suddenly stops. When Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) levels are no longer detectable, your body will not experience the exceptional health benefits, and energy-optimizing results expected from a testosterone injection program.

Another critical concern for men is testicular atrophy in patients that participate in testosterone therapy and may experience shrinkage of the testes, This occurs as the result of the lack of testosterone, and sperm production has been shut down, in response to the testosterone therapy.

What does post cycle therapy (PCT) consist of, an example?

Your post cycle therapy consists of a testosterone secretagogue to stimulate the secretion of endogenous testosterone from the testes to reignite natural production. The medication mimics the signal from your brain. The Luteinizing Hormone (LH) induce the production of testosterone. An example of a testosterone secretagogue is human chorionic gonadotropin (hCG), which is administered either using sublingual troches or subcutaneous injections once or twice a week during therapy and then on 10–15 consecutive days as part of a post cycle therapy (PCT). Human chorionic gonadotropin (hCG), mimics Luteinizing Hormone (LH) to stimulate testosterone production by the testes. It works by effectively tricking the testes into thinking that they are being instructed to produce testosterone, even though levels are comfortably elevated because of the injectable testosterone therapy. The testosterone production stimulated by human chorionic gonadotropin (hCG) is not sufficient to sustain healthy testosterone levels on its own, but that is not the reason for this supplementation. The purpose is to ensure that the testes remain functioning during therapy to help avoid any shrinkage or atrophy.

You will also take an anti-estrogen or aromatase inhibitor. For example, Clomid/clomiphene blocks certain types of estrogen from getting to the pituitary and hypothalamus, where it elicits signals that stop testosterone production. Anti-estrogens or aromatase inhibitors also help to reactivate the standard functionality of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) signaling, while also helping to flush out any residual estrogen that has accumulated during therapy. The estrogen that collects during treatment is responsible for many of the adverse side effects associated with testosterone therapy.

An example of a post cycle therapy (PCT) protocol is as follows (note that the exact drug and dose prescribed will depend on the specific information contained within each patient file, as well as the individual patient goals):

  • 250–800 units of a testosterone secretagogue every day for ten consecutive days
  • One estrogen blocker or antagonist by mouth every day for 10–15 straight days

Without the proper understanding of what is explicitly occurring within the endocrine system during these crucial weeks, as well as a lack of knowledge of which compounds to utilize, what each compound does, and how to properly use them, serious problems can result.

post cycle therapy

The Hypothalamic Pituitary Testicular Axis (HPTA):

The (HPTA), which is an axis interconnected endocrine glands in the body that deals with control the production Testosterone.

Post-Cycle-therapy:

Outlined above is a diagram of the Hypothalamic Pituitary Testicular Axis (HPTA), Regulates the body produces the amount of Testosterone at any given time. Every individual is essentially programmed by (DNA) genetics as to maximum Testosterone they will provide.

The Hypothalamic Pituitary Testicular Axis (HPTA) and the functions that undergo a negative feedback loop, and the body will reduce secretion of Testosterone, f have too much Testosterone the body will be detected, known as the negative feedback loop. This controlled by the hypothalamus, which is mostly considered the ‘master’ gland for all endocrine system and the hormonal functions in the body. The negative feedback will loop ultimately in the body to attempt to maintain the hormonal homeostasis, and all endocrine glands operate by way of the negative feedback loop in one way or another in varying degrees, In the case of post cycle therapy, the concern is a negative feedback loop of the (HPTA).

Within the Hypothalamic Pituitary Testicular Axis (HPTA), the concern during post cycle therapy (PCT) is the restoration and regulation of the following five hormones to homeostasis:

  • GnRH (Gonadotropin Releasing Hormone)
  • LH (Luteinizing Hormone)
  • FSH (Follicle Stimulating Hormone)
  • Testosterone production

The Hypothalamic Pituitary Testicular Axis (HPTA), the hypothalamus, which will detect a need for the human body to produce more Testosterone, and will release varying amounts of GnRH, Is a hormone that signals the pituitary gland, to begin the production and release of two essential gonadotropins: Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH). Two hormones that work together to start the secretion of Testosterone.

Two primary hormonal factors serve to inhibit, reduce, suppress, or shut down Testosterone production in the Hypothalamic Pituitary Testicular Axis (HPTA):

  • Testosterone Excess
  • Estrogen Excess

Although there exist other hormones that serve to inhibit and suppress Hypothalamic Pituitary Testicular Axis (HPTA) function (such as Progestins and Prolactin), these are the two primary conditional hormones that are of concern. When the hypothalamus detects excess levels of Testosterone and Estrogen in the body (either from the use of exogenous androgens on an testosterone therapy or otherwise), the hypothalamus will act to attempt to restore a balance by essentially doing the opposite of what was previously described. The hypothalamus will reduce or stop its production of GnRH, which halts production of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH), which ultimately reduces or halts production of Testosterone. Until the hypothalamus’ ideal hormonal environment is restored, the output of the various signaling hormones within the (HPTA) will not begin, and this will often require months for the body to do this on its own without the intervention of any Testosterone stimulating agents. The reason as to why the recovery of the (HPTA) naturally takes such a long time should be very clear due to the described workings of the (HPTA).

This fundamental understanding of the mechanisms of the Hypothalamic Pituitary Testicular Axis (HPTA) and negative feedback loop described above is essential to understanding how and why a proper post cycle therapy (PCT) program must be developed and utilized following an testosterone therapy.

Determining Factors In Difficulty Recovering the Hypothalamic Pituitary Testicular Axis (HPTA):

With testosterone therapy use, there are several different major determining factors in how much difficulty an individual will experience in recovery of their Hypothalamic Pituitary Testicular Axis (HPTA) and endogenous Testosterone function during post cycle therapy (PCT).

They are the following factors, in no particular order of importance:

  • Individual response
  • Type of testosterone(s) used
  • Length of the cycle (degree of testicular desensitization)

Individual response:

Every single individual will respond differently to any chemical, compound, testosterone, food or drug in existence. While some individuals might experience no Hypothalamic Pituitary Testicular Axis (HPTA) suppression or shutdown at all, other individuals might experience severe Hypothalamic Pituitary Testicular Axis (HPTA) suppression and closure to the extent where they might require far more extended periods to ensure full recovery than most. This, like anything else, is a spectrum whereby there are the very ‘lucky’ individuals that recover very quickly and easily on one end of the spectrum, and the ‘unlucky’ individuals that have extreme difficulty recovering during post cycle therapy. In between the two extremes is the average. Once again, this is due to the individual’s genetic programming as to how the Hypothalamic Pituitary Testicular Axis (HPTA) will respond and attempt to maintain homeostasis.

Type of Testosterone Therapy(s) used:

All testosterone therapy exhibit suppression or shutdown of the Hypothalamic Pituitary Testicular Axis (HPTA) through the mechanisms of the negative feedback loop, and there are no exceptions to this. Various testosterone therapy are known as being mildly suppressive, while others are identified as being profoundly suppressive. This is all reliant on multiple different reasons, many of which will not be discussed here. In any case, no matter how mild or severe an testosterone therapy exerts Hypothalamic Pituitary Testicular Axis (HPTA) suppression, all testosterone therapy when utilized for typical cycle lengths of weeks at a time will eventually cause the Hypothalamic Pituitary Testicular Axis (HPTA) to shut down, or at the very least severely suppress its hormonal signal processes.

Length of the cycle degree of testicular desensitization:

This is perhaps the most important and most influential factor. As the range of testosterone therapy use continues, the majority of the Leydig cells of the testes remain dormant and inactive, and the longer these interstitial cells stay dormant and idle, the higher the difficulty is essentially getting these cells to respond to the stimulus of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) once again. It has been discovered in studies that the issue of recovery of the Leydig cells following testosterone therapy use is not due to a lack of Luteinizing Hormone (LH), but due instead to the desensitization of the Leydig cells to (LH). In one study in which exogenous Testosterone was administered to male test subjects for 21 weeks, Luteinizing Hormone (LH) levels were suppressed shortly after beginning administration. However, at the end of the 21 weeks, Luteinizing Hormone (LH) levels were observed to rise within three weeks once the exogenous Testosterone administration stopped, but Testosterone levels did not arise until many weeks later in most of the test subjects.

Recovery During The Post Cycle Therapy (PCT).

To stimulating hormonal recovery during post cycle therapy, it is essential for individuals to understand that the use of any medication except for a single select one or two is inadequate for hormonal recovery during post cycle therapy (PCT). Ideally, all post cycle therapy programs should be a multi-component post cycle therapy (PCT) program that includes several different compounds that work in tandem with one another to provide the most effective and fastest possible Hypothalamic Pituitary Testicular Axis (HPTA) recovery following an testosterone therapy.

The three categories of compounds are in order of importance:

  • SERMs (Selective Estrogen Receptor Modulators)
  • Aromatase Inhibitors
  • HCG (Human Chorionic Gonadotropin)

SERMs:

Classes of drugs in the SERM category include: Nolvadex (Tamoxifen Citrate), Clomid (Clomiphene Citrate), Raloxifene, and Fareston (Toremifene Citrate). The nature of a SERM is that it exhibits mixed Estrogen agonist and Estrogen antagonist effects on the body. This means that although a SERM might block the effect of Estrogen at the cellular level in specific tissues, it can enhance Estrogenic impacts in other areas of the body. These can be positive effects as well as adverse effects. Nolvadex, for example, exhibits Estrogenic agonistic effects in the liver, which is a positive effect, as its effects here result in a positive change in cholesterol profiles (something desired by many). All SERMs to varying degrees serve to act as an Estrogen antagonist in this area, working to mitigate Estrogen’s effects on breast tissue, reducing or blocking the side effect of gynecomastia. Regarding the impact of SERMs on endogenous Testosterone stimulation, they serve to act as an Estrogen antagonist at the pituitary gland, triggering the release of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) as a result. Elevated levels of Estrogen in men can and does suppress the output of endogenous Testosterone via the negative feedback loop, leading to hypogonadism. SERMs for this purpose are an essential addition to any post cycle therapy (PCT) protocol and are not to be excluded under any circumstance. Regardless of this, however, the sole focus should not be on SERMs.

Aromatase Inhibitors:

These are compounds such as Aromasin (Exemestane), Arimidex (Anastrozole), and Letrozole (Femara). Rather than block the activity of Estrogen at the cellular level in different tissues, aromatase inhibitors (AIs) serve to lower total circulating Estrogen levels in the body by way of inhibiting the aromatase enzyme, which is the enzyme responsible for the conversion of androgens into Estrogen. The transformation of androgens into Estrogen results in excess Estrogen levels, which, as explained earlier in this article, will trigger the negative feedback loop leading to suppression of Testosterone production. By way of lowering total circulating blood plasma Estrogen levels, AIs will positively engage the negative feedback loop and result in the release of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) for the manufacture and secretion of more Testosterone. This is mainly due to the hypothalamus realizing that circulating. Estrogen levels are too low and will attempt to increase circulating levels of Testosterone for a portion of the Testosterone secreted to be able to become aromatized into Estrogen to restore the hormonal balance. The other importance of aromatase inhibitors is the ability to mitigate the Estrogenic effects of human chorionic gonadotropin (HCG), which will be explained shortly. It is important to note, however, that the majority of aromatase inhibitors do not comply very well with SERMs such as Nolvadex, and those particular choices should be made in regards as to which AI is used during post cycle therapy (PCT).

HCG:

Human Chorionic Gonadotropin is, for the most part, synthetic Luteinizing Hormone (LH). It is a protein hormone manufactured in high amounts by pregnant females that contains a protein subunit that is 100% identical to Luteinizing Hormone (LH), and therefore when administered to men, it will mimic the action of Luteinizing Hormone (LH) in target tissues, such as the testes. What results is an increase in Testosterone production via stimulation of the Leydig cells by human chorionic gonadotropin (HCG). Human chorionic gonadotropin (HCG) should never be utilized alone, as its nature as a gonadotropin will itself trigger a negative feedback loop whereby once human chorionic gonadotropin (HCG) is used, the pituitary gland will halt output of Luteinizing Hormone (LH) until human chorionic gonadotropin (HCG) use has discontinued. Therefore, human chorionic gonadotropin (HCG) must be utilized with a SERM and especially an aromatase inhibitor, as human chorionic gonadotropin (HCG) has demonstrated to increase aromatase activity in the testes, resulting in rising Estrogen levels.

Putting Them Together:

The reader may be wondering which compounds to select of the three categories listed, and how to use them properly. The answer lies in understanding the properties of each and, in interpreting these properties, how to use them efficiently and appropriately.

Human chorionic gonadotropin (HCG):

The first item to be examined will be human chorionic gonadotropin (HCG). The majority of testosterone therapy users from the 1960s – mid-1980s did not even utilize any compounds for hormonal recovery, and the term post cycle therapy (PCT) did not even exist at that time. When the use of human chorionic gonadotropin (HCG) became increasingly popular (circa 1980), it was the only compound utilized. Since then, the medical and scientific understanding of such things has increased exponentially, and there should be no reason for any informed and adequately educated individual to utilize human chorionic gonadotropin (HCG) on its own for post cycle therapy (PCT). When used in conjunction with one of the other two categories of compounds (an AI and a SERM), the dynamics change considerably.

It has been mentioned already that much of the difficulty in recovering the Hypothalamic Pituitary Testicular Axis (HPTA) following an testosterone therapy is the result of Leydig cell desensitization. Human chorionic gonadotropin (HCG) is necessarily an analog of Luteinizing Hormone (LH), and the testes after a prolonged testosterone therapy would be as equally desensitized to human chorionic gonadotropin (HCG) as they are to Luteinizing Hormone (LH). The human body, however, produces Luteinizing Hormone (LH) amounts on its own that is far too inefficient for proper and rapid Testosterone production. The body’s natural increase of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH), evidenced by the study referenced earlier in which it was not until three weeks when Luteinizing Hormone (LH) levels only began to reach the standard physiological measurements following the cessation of Testosterone. Therefore, the body’s natural Luteinizing Hormone (LH) production does not provide a high enough dose for stimulation, nor an immediate stimulus to the tests required for the initial increase in Testosterone needed during the post cycle therapy weeks.

Human chorionic gonadotropin (HCG), utilized in a specific manner during the first 1 – 2 weeks of post cycle therapy (PCT) at a dose of 100-1,500IU every 2 days, is what allows the individual to provide the testes with a high dose to provide them with a ‘shock’ effect, and sustain this shock effect on the Leydig cells of the testes for a sustained period of the first 1 – 2 weeks of post cycle therapy. Studies have demonstrated the incredible effectiveness of human chorionic gonadotropin (HCG) for this purpose, it been suggested that human chorionic gonadotropin (HCG) therapy is utilized to treat low testosterone and hypogonadism. Following this line of thought, the other two compounds (the SERM and the AI) are to be used as supportive compounds for human chorionic gonadotropin (HCG) use in this 1 – 2 week period, and after human chorionic gonadotropin (HCG) is discontinued early on in post cycle therapy (PCT), only the SERM is to be used in order to carry along the hormonal recovery process.

In spite of the good news in regards to the ability for human chorionic gonadotropin (HCG) to assist in hormonal recovery, there are still two remaining issues to be addressed:

  • The fact that human chorionic gonadotropin (HCG) causes increased production of aromatase, leading to increased Estrogen levels.
  • Following the discontinuation of human chorionic gonadotropin (HCG), the body is left with very little endogenous Luteinizing Hormone (LH), and Follicle Stimulating Hormone (FSH) production due to the exogenous administration of human chorionic gonadotropin (HCG).

Aromatase Inhibitors:

Aromasin (Exemestane) Above All Else The first of the two remaining issues to be addressed will be the fact that human chorionic gonadotropin (HCG) will trigger increases in testicular aromatase expression, and result in Estrogen increases in the body. It should also be noted that it will cause an increase in testicular progesterone levels. Estrogen rising is, of course, undesirable during post cycle therapy (PCT), as it has already been explained that Estrogen will trigger suppression of endogenous Testosterone production, and there is no doubt that any individual wishes to encounter Estrogenic side effects during post cycle therapy (PCT) either.

Therefore, the option here is to include an aromatase inhibitor. However, there exists a big problem in regards to the other two of the three major aromatase inhibitors (Arimidex and Letrozole). The issue is the fact that in a post cycle therapy (PCT) program that includes the use of SERMs such as Nolvadex and Clomid, which are known as essential components to a post cycle therapy (PCT) program, Arimidex and Letrozole have direct negative interactions with Nolvadex. The problem here is that Arimidex (or Letrozole) and Nolvadex both directly counteract one another. One study has demonstrated that when Arimidex is utilized with Nolvadex, Nolvadex will decrease the blood plasma concentration of Arimidex (as well as Letrozole, another commonly used aromatase inhibitor). The conclusion here is that the use of Arimidex or Letrozole with Nolvadex together is a terrible idea and may work together in a post cycle therapy (PCT) protocol. Aromasin completely circumvents this problem, as it has been demonstrated to have no interactions what so ever with Nolvadex, unlike the other two aromatase above inhibitors. In one study, Aromasin displayed no such reduced effectiveness or any reduced blood plasma levels when utilized with Nolvadex.

The other benefit of selecting Aromasin over all other AIs is the fact that Aromasin has demonstrated in several studies to impact cholesterol profiles in a negative manner far less than other aromatase inhibitors have, wherein one particular review on cancer patients, 24 weeks of Aromasin (Exemestane) administration held no impact on cholesterol profiles. Some other studies have also demonstrated a nil effect on cholesterol profiles from the use of Aromasin. Although there have also been some studies that have shown a negative impact on cholesterol profiles resultant from Aromasin use, it is evident that there is not as a significant or as a negatively impacting effect from Aromasin on cholesterol as other aromatase inhibitor.

Finally, in addition to these benefits from Aromasin, it is evident that Aromasin holds the ability to increase Testosterone levels in males as demonstrated by studies. For example, one particularly notable study selected 12 healthy young male test subjects, and were administered random Aromasin doses of 25mg and 50mg for a 10 day period, and not only was Estrogen suppressed by a significant amount (38%), but Testosterone levels in the test subjects were observed to have increased by an incredible 60%.

Following these details, Aromasin would be the best possible aromatase inhibitor of choice to combat the increased aromatase activity caused by human chorionic gonadotropin (HCG). Therefore, Aromasin would then be utilized at a full 25mg daily dose, and only while human chorionic gonadotropin (HCG) is used. Once human chorionic gonadotropin (HCG) is discontinued, Aromasin too should be halted.

The only following issue to cover now is that of stimulating and maintaining proper endogenous Luteinizing Hormone (LH) release to carry recovery along until the body can become self-sufficient once again.

Nolvadex and Clomid: 

The question is often asked among the testosterone therapy using community: Clomid or Nolvadex? Which one for post cycle therapy (PCT)?

First of all, the best possible addition to human chorionic gonadotropin (HCG) in a post cycle therapy (PCT) protocol is Nolvadex (Tamoxifen Citrate), as studies have demonstrated that human chorionic gonadotropin (HCG) and Nolvadex utilized together have exhibited a remarkable synergistic effect in terms of stimulating endogenous Testosterone production and that Nolvadex will actually work to block the desensitization effect on the Leydig cells of the testes caused by high doses of human chorionic gonadotropin (HCG). This is very important because just as too little Luteinizing Hormone (LH) secretion for extended periods can cause desensitization to gonadotropins, too much gonadotropin stimulation (in the form of human chorionic gonadotropin (HCG) or otherwise) will likewise create a desensitization effect.

Secondly, Nolvadex on an mg for mg basis is far more effective than Clomid in stimulating endogenous Testosterone production, as well as being a more cost-effective choice than Clomid itself. Studies have demonstrated that 150mg of Clomid (Clomiphene Citrate) administered daily raised endogenous Testosterone levels of 10 healthy males by approximately 150%, while incidentally, 20mg of Nolvadex (Tamoxifen Citrate) daily raised endogenous Testosterone levels by the same amount. It is very evident here that Clomid is very useful for this purpose, but Nolvadex seems to be a more cost-effective choice seeing as though it is more effective than Clomid when compared mg for mg. The benefits of Nolvadex over Clomid do not end there – Clomid, although it does exhibit Estrogen antagonist effects at the pituitary gland as Nolvadex does, actually shows Estrogen agonist effects there too. What this means is that Clomid will work in varying degrees as an Estrogen at the pituitary gland, triggering the negative feedback loop and reducing the output of Testosterone stimulating gonadotropins Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH). This is a severe problem during post cycle therapy, which is a period in which individuals are trying to recover their Hypothalamic Pituitary Testicular Axis (HPTA) function rather than halt it even further. Ideally, one would want a SERM that exhibits almost 100% Estrogen antagonistic effects on the pituitary gland, and Nolvadex is the perfect choice for this.

When it comes to the dosing aspect of Nolvadex, The standard dose for post cycle therapy (PCT) and for stimulating the release of GnRH (Gonadotropin Releasing Hormone), Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH), and ultimately Testosterone is that of a single Nolvadex dose of 20 – 40mg daily. In all studies involving Nolvadex doses used to stimulate endogenous Testosterone production, only 20 – 40mg daily of Nolvadex was utilized, and it has been shown that doubling the dose to 40mg or any higher will not produce any significant difference in endogenous Testosterone secretion. The only reason why many elects to utilize 40mg daily of Nolvadex for the first 1-2 weeks of a post cycle therapy (PCT) program is to achieve optimal peak blood plasma levels quicker to ensure Hypothalamic Pituitary Testicular Axis (HPTA) recovery faster.

The ideal post cycle therapy protocol for 4 – 6 weeks Total post cycle therapy (PCT) time (depending on the recovery ability of the individual):

01) Weeks 1 – 2:

  • human chorionic gonadotropin at 1000iu/E2D.
  • Aromasin (Exemestane) at 25mg/day.
  • Nolvadex (Tamoxifen Citrate) at 40mg/day.

02) Weeks 2 – 6:

  • Nolvadex or (Tamoxifen Citrate).

Additional and Optional, Vitamins, Supplements, Compounds to Aid During post cycle therapy (PCT), Aside from the principal components discussed, various other parts are mostly optional, but still very useful for hormonal recovery of the Hypothalamic Pituitary Testicular Axis (HPTA) during the post cycle therapy weeks.

Vitamin B12 Health Benefits, There has been a lot of controversy over whether or not there is indeed a benefit from taking B12 supplements. Some doctors suggest that as long as a person is not vegan (though probiotics in the gut can produce some B12), they are probably getting sufficient B12 from the basic foods they are ingesting.

vitamin b12

Let us reference some studies:

There is documented research from the Framingham Study suggesting that 40% of all people are deficient in B12. The American Journal of Clinical Nutrition researched in 2009, and they published a study suggesting close to 6% of U.S. and U.K. residents over the age of 60 are B12 deficient. Another 20% were referenced as “marginal status.”

Vitamin B12 Health Benefits has the most multifaceted and prevalent chemical structure of all vitamins. One area where it differentiates from other vitamins is in the fact that it’s the only vitamin that contains a metal commonly referred to as Cobalamin, which is also a universal term for all the various compounds that may have some B12 properties in it.

B12 can improve energy by aiding in thyroid function and cellular methylation, That being said, B12 is not only useful in supporting healthy energy levels. It is unequivocally essential to life and whole existence. People deficient in B12 will suffer from serious health issues if the problem is not addressed.

What role B12 plays in the following human biological processes:

  • Nerve and brain regeneration
  • Adrenal gland support
  • Male and female reproductive health
  • Nutrient absorption
  • Red blood cell formation
  • Cellular energy
  • Memory recall
  • DNA synthesis

Here are some of the risks associated depleted B12 levels are:

  • Pernicious anemia
  • Migraine headaches
  • Macular degeneration
  • Tinnitus
  • Fatigue (adrenal fatigue and CFS)
  • Multiple sclerosis
  • Memory loss
  • Neuropathy
  • Anemia
  • Asthma
  • Shingles
  • Kidney disease
  • Depression

Vitamin B. Capsules B1 B2 B6 B12 on white isolated background.
November 7, 2018 by Joseph Fermin 0 Comments

The Importance of Hormone Replacement and in our Life

The Importance of Hormone Replacement and Vitamin in our Life

Hormone Replacement in the body needs a minimum amount of vitamins, amino acid, and minerals each day to remain healthy and function properly. A balanced diet supplies typically sufficient Hormone Replacement. However, severe disorders can still develop if the food does not meet if your body doesn’t use it. Symptoms of the deficiency in vitamins and minerals usually appear when is already too late. For example, people who don’t have enough Vitamins A, B1 and B2 suffer from tiredness, chapped lips, mental or emotional disturbances, and loss of appetite, among other problems.

vitamin b12

The common causes of vitamin deficiencies include poor eating habits, Drugs, and emotional stress, alcoholism. The improper absorption of vitamins and minerals in your body (usually is due to the liver or intestinal disorders), also the intake of medicines that interfere with the ingestion of vitamins or lack of exposure to sunlight. If you always feel sluggish and suffer from chronic health-related inconveniences, you might be short of the vitamins your body needs to function on an optimal level. Doctors will usually prescribe Growth Hormone Replacement Therapy supplements that address the lack of vitamins and minerals that your body needs… However, also keep in mind not abuse it, as an excess of vitamins can also be harmful in the body.

The right vitamins and minerals should accompany proper food consumption. Vitamins serve as buffers if your diet does not meet your daily requirements. Surely you can’t calculate how much vitamins or minerals your body intakes in every meal you consume daily, and while most people take vitamins and minerals to avoid common problems or deficiency-related diseases, not every product works or cater to what your body requires or need.

The critical component you must look for in Growth Hormone Replacement Therapy is the vitamin B-complex, like B6, B12, D, E, folic acid, and more. Aside from being dietary supplements, these so-called B vitamins have been known to help combat certain types of cancer or heart diseases ailments. While there remains the hard-lined link between cancer and a daily intake of B complex vitamins, studies have suggested their preventive powers to help raise the importance of daily doses of vitamins and minerals into our body.

The old belief that proper dieting is enough to keep you going has become a myth, and people are starting to educate them self on the power of hormones and now It is time to invest in your health with Hormone Replacement Therapy, Vitamins and Nutraceutical medication. Now is up to us whether we want to admit it or not, We need vitamins in our body. But when we think about it, vitamins Hormones are probably the cheapest type of insurance readily available in the market right now. Who are we to say no?

AAI Rejuvenation clinic specializes in treating chronic age-related diseases and symptoms. Our primary goal is to promote wellness and vitality by focusing on the early detection of hormonal imbalances. A therapy through AAI is individualized to suit your unique needs in alignment with specific health and fitness goals.

Our programs supersede other clinics in that we provide a combination of three crucial elements for successful treatment. First, we prescribe state of the art pharmaceutical support supplied by our specialized pharmacies. To partner with AAI, these pharmacies have to be by the highest regulations for injectable medications.

Most common deficiencies are treated with Testosterone, Sermorelin, HGH options or vitamins Therapy. We provide all supporting medications to ensure your endocrine system is functioning at a superlative level. Secondly, we follow with the latest in plant-based medicine to help cellular support during and after treatment enhancing your benefits and minimizing your ailments. Lastly, we provide the best patient advocate support available.

Our advisers have been trained strictly by our physicians to ensure that you are empowered to understand your treatment from start to finish. We genuinely believe in our therapies because we have experienced the life-changing benefits first hand and through our patients.

Amino acids are nitrogen-containing nutrients that form the building blocks of peptides and proteins. Hundreds of different types of protein are vital for growth, development, metabolism, and sustaining life; therefore, having a sufficient balance of amino acids is essential for these same processes. Humans have 20 amino acids. Of these, the human body can produce 11. The other nine must be consumed through the diet or supplements; therefore, they are considered “essential.” Our associated laboratories are the very best in the country and compound only the highest quality nutraceuticals. Although everyone says this, we can prove it.

 

More Vitamin and amino Acid Information:

September 6, 2018 by Joseph Fermin 0 Comments

Intracavernosal (ICI) Therapy for Erectile Dysfunction

Intracavernosal (ICI) Therapy Is the most powerful,
and safe Erectile Dysfunction treatment

Intracavernosal (ICI) therapy is the most powerful and effective option available treatment options for Erectile Dysfunction, Guaranteed 98% results with patients and there are several treatments and options for Erectile Dysfunction (ED), and Intracavernosal (ICI) Therapy is number one and the most potent, useful available option. Intracavernosal (ICI) therapy is safe in men, and has been used successfully to treat erectile dysfunction (ED) since the 1970’s in the United States, Intracavernosal (ICI) therapy is non-systemic, and that this medication does not get absorbed into your body and eliminates the risk of any reactions, and that means that this medication works reliably, every time, without restrictions on food, alcohol or drugs.

Intracavernosal (ICI) therapy is by far the most effective treatments available, now in days and It is safe and suitable for men with Erectile Dysfunction problems, regardless of age or medical condition Intracavernosal (ICI) therapy will work. It’s a higher form of erectile dysfunction (ED) treatment for men and yet simple to apply or to use. Intracavernosal (ICI) Therapy has widely used since the mid-70’s. Medical professionals and clinical advisor who specialize in this form of erectile dysfunction (ED) treatment use various combinations of medications.

Benefits of (ICI) INTRACAVERNOUS for ED:

  • Instant, and 98% powerful results
  • Maintain full erection quickly with or without stimulation
  • Control your construction for 30, 60 or 90 minutes
  • Improved stamina and sexual performance
  • No side-effects and Safe and convenient treatment
  • No restrictions on food, alcohol or medications
  • Guaranteed results over 90% of patients

Intracavernosal (ICI) therapy Involves the painless in a small amount of a pre-determined combination of vasodilators into the spongy tissue of the penis and using an auto-applicator. The combination causes dilatation of the penile arteries and penile tissues, increasing blood flow to the penis, which then stored in the erectile chambers. As pressure builds up against an unyielding envelope (called a tunica albuginea), venous outflow blocked, an erection develops within a few minutes. This induced erection feels perfectly natural and healthy with the exception that it will not go down after ejaculation. The prescribed formula is individually tailored to allow the construction to last approximately 30-60 minutes regardless of the occurrence of ejaculation or the state of mind. Once the Intracavernosal (ICI) therapy protocol established, this treatment works predictably and reliably every time.

Intracavernosal Injection (ICI) Therapy

The medicine used in Intracavernosal (ICI) therapy is a combination of vasodilators, each of which is FDA-approved, known as papaverine, phentolamine, atropine, and prostaglandin E-1. Since Intracavernosal (ICI) therapy is a localized form of treatment, the side-effects are minimal and local. Its overwhelming success rate, minimal side-effects, and ease of use. Intracavernosal (ICI) therapy is a preferred choice for most patients who want natural access to this type of medical treatment and for patients who do not respond to traditional medications options or suffer from the side-effects of the oral drugs, Intracavernosal (ICI) therapy is a welcome relief since it works well in most cases?

The benefits of (ICI) INTRACAVERNOUS:

  • (ICI) has an overwhelming success, it works in the majority of patients, even in those who have tried this treatment before elsewhere, The medication applied locally; hence there are no known systemic side-effects.
  • (ICI) can use without restriction to food, wine or other medicines.
  • (ICI) is easy to apply using an Autoject which merely operates with the press of a button.
  • (ICI) Is reported to be the cure in many patients with Erectile Dysfunction. Results may vary depending on the underlying health problems of each patient and the severity of (ED)

Now, Even though Intracavernosal (ICI) therapy is useful in most men, it may not be as effective in advanced Erectile Dysfunction when most of the usually elastic tissue has stored by fibrosis, and a common end-result of delayed of treatment, and only the remaining solution is the insertion of a penile prosthesis.

Intracavernosal (ICI) Therapy and psychological Erectile Dysfunction

Men with recent-onset psychological Erectile Dysfunction still have a reasonably intact physiological function. Restoring the confidence level with repeatedly successful erections helps resolve the psychological conflicts; the erectile function tends to improve. Untreated, psychological Erectile Dysfunction can deteriorate to physical Erectile Dysfunction, a process called “disuse atrophy,” which is then more difficult to reverse.

Intracavernosal (ICI) Therapy and physical Erectile Dysfunction

The penile tissue is a vascular organ that requires a healthy supply of oxygenated blood to stay supple and responsive to sexual stimulation. Such provision comes with the occurrence of regular erections, either sexually-induced or physiologically-induced (REM sleep).

A course of Intracavernosal (ICI) therapy treatment results in regular erections that last 30-60 minutes each time. Each (ICI)-induced construction helps rebuild the sexual confidence, a psychological benefit, as well as the natural erectile reflex, a physical advantage.

Can men increase long-term improvement?

To optimize your chance of long-term improvement, complete the full course of treatment as recommended, look after your general health, maintain a healthy diet and an active lifestyle, reduce stress and control your vascular risk factors if any. www.aaiclinics.com

August 10, 2018 by Joseph Fermin 0 Comments

Nutraceutical and Weight Loss Therapy

Nutraceutical and Weight Loss

Weight Loss therapy

There are now millions upon millions of options for weight loss therapy and nutraceuticals available on the market today. Many fads that, for the most part, do actually work, but the end result for 99% of the participants is always the same; gaining back more weight loss therapy they actually started off with.

The one thing that these diet programs have all wrong is the notion that the “same” therapy program will work for every single person that tries it. That is propaganda. Whoever tries to convince you that if something worked for one person, then it must work for you as well, is lying to you and does not have your best interest in mind. Another very important, yet logical characteristic of “being thin” is the actual need to change your entire lifestyle… that is literally the only way to weight loss therapy and keep it off. If you go back to what you were doing before, you will just end up the way you looked and felt before.

Now that that’s out of the way, let’s talk about options available to help you on your path to the new you. Options that may even help you to accelerate the process a bit. For the core group, the whole point of founding AAI Rejuvenation Clinic was to establish an organization based on the premise that patient care and focus, really putting the patients first, is of utmost importance and the kind of focal structure missing in most medical establishments today. Our logical determination is that if we actually focus on helping patients and honestly answer queries related to their health and wellness goals, our patients will be loyal to our process and to our establishment; happy to be a part of the AAI Rejuvenation Clinic family and satisfied with our level of service, respect and, overall, their final goals and end results.

All Weight Loss Therapy are NOT Created Equal!

Medicinal therapies and protocols cannot be a one-size-fits-all structure. Each individual patient’s specific physiological characteristics, their daily routine, as well as their actual goals and aspirations must be taken into consideration when drawing up and organizing a plan of attack to drop those unwanted pounds and inches.

For the most part, the nutritional diagnosis will be the focus of your protocol assembling. Additionally, hormone treatments are very commonly incorporated into most diet regimens to help patients needing the additional assistance in weight loss due to physiological apprehensions.

Though Gonadotropin is one of the options available at AAI Rejuvenation Clinic as a weight loss therapy program, the reality is that it is not one of the healthiest weight loss options available out there and we do try to stray from incorporating it into our agendas. Needless to say, it is a program that helps some participants lose their desired weight and it can be effective if very properly administered and unmistakably followed. What we do different, in cases where interested patients qualify for these another hormone related weight loss options, such as the Gonadotropin hormone replacement program, is we integrate an array of vitamins, probiotics, amino acids and other such supplementing pharmaceuticals in an effort to cater to the immune system, which is one of the strongest downfalls of participating in such a protocol, which requires such a minimal amount of caloric consumption daily.

Why AAI Rejuvenation Clinic is Different.

At AAI Rejuvenation Clinic, we do what is best for your body in terms of helping you reach your health and wellness goals. We’ve learned that many times when a patient is having problems reaching their weight goals, the association has to do with a bad combination of food choices for that individual specifically. The way the body processes food is very different from one person to another, so understanding a person’s eating habits in conjunction with proper and adequate blood tests can really help zero in on a program, and the right supplementing nutraceuticals, to help eliminate whatever toxins may be preventing them from losing weight or, whatever hormone imbalance may be slowing down their weight loss process. Whatever metabolic issue may be obstructing a person’s ability to reach their weight loss goals can be addressed once it’s properly diagnosed.

July 27, 2018 by Joseph Fermin 0 Comments

Hormone Therapy Benefits & Risks in Women

Hormone Therapy Benefits & Risks in Women

Hormone Therapy Benefits is one of the government-approved treatments for relief of menopausal symptoms. These symptoms, caused by lower levels of estrogen at menopause, include hot flashes, sleep disturbances, and vaginal dryness. Hormone Therapy here is some background information.

Hormone Therapy Benefits & Risks in Women

There are Three-Benchmark Stages of Natural Menopause:

Perimenopause (or the menopause transition) is the span of time between the start of symptoms (such as irregular periods) and one year after the final menstrual period.

Menopause is confirmed one year (12 months) after the final menstrual period. Postmenopause is all the years beyond menopause.

There are Basic Types of Hormone Therapies:

Estrogen Therapy means hormone-only therapy. Estrogen is the hormone that helps most menopausal symptom relief. Estrogen Therapy is prescribed for women without a uterus due to a hysterectomy.

Estrogen-Progesterone-Testosterone:

This Therapy means combined testosterone, estrogen plus progestogen therapy. Progestogen is added to Therapy to protect women with a uterus against uterine (endometrial) cancer from estrogen alone.

There are General Ways To Take Hormone Therapies :

The Systemic products circulate throughout the bloodstream and to all parts of the body at a cellular level. They are available in oral tablet, patch, gel, spray, or injection and other forms.

Local (nonsystemic) products affect only a specific or localized area of the body. They are available as a ring, cream, and tablet can use for vaginal symptoms.

Hormonal Benefits:

Hundreds of clinical studies all around the world have been done and have provided evidence that systemic Hormone Therapy Benefits (estrogen with or without progestogen and testosterone) These hormones are useful in helping such conditions as vaginal dryness, night sweats, hot flashes, bone loss and more. These benefits can lead to improved depression, sleep, sexual relations, and also the quality of life.

One of the primary indications for Hormone Therapy is hot flashes, night sweats, vaginal dryness, and prevention of osteoporosis.

The Risks:

To minimize health risks, Hormone Therapy Benefits recommended at the lowest effective dose for the shortest period. The real concern about hormone safety is with long-term use of systemic Estrogen Therapy or Estrogen Progesterone Therapy.

As a result in Women’s Health Initiative (WHI) trial in 2002, the U.S Food & Drug Administration, and Health Canada require all estrogen-containing prescription therapies to carry a “black box” and warning in their prescribing information about the adverse risks of Hormone Therapy.

Although only two products, was studied in the Women’s Health Initiative, Premarin, and Prempro, the risks of all Hormone Therapy products, including “natural” bioidentical and compounded hormones, should be assumed to be similar until evidence shows otherwise.

Most of the risk of breast cancer associated with Estrogen Progesterone Therapy. Both Estrogen Therapy and Estrogen Progesterone Therapy have associated with stroke, heart attack and the body increase in blood clots in the veins, also these risks can be higher in women over 60’s.

The Weighing in the Benefits & Risks:

There is no single way to ensure the best possible quality of life around menopause and beyond. Each woman is unique and must consider her discomfort against her fear of treatment. The risk defined as the possibility or chance of harm; it does not indicate that damage will occur. Generally, Hormone Therapy risks are lower in younger women than initially reported in all women ages 50 to 70 combined. It now believed that women taking estrogen alone—women who have had their uterus removed by a hysterectomy—have a more favorable benefit-risk profile than those taking Estrogen Progesterone Therapy, and this is especially true for younger menopausal in women (in their 50s or within ten years of menopause) than for older women.

Medical professionals have modified their views about the role of hormones as more research conducted and what are the benefits. Experts agreed that there is much to learn, they don’t necessarily address all of the issues an individual woman faces. Only she, with the counsel of her health care providers, can do that.

Only after examining and understanding her situation and after a thorough consultation with her clinician can a woman make the best treatment choice. As new therapies and guidelines are available, and as a woman’s body changes over time, reevaluation and adjustments should make.

Hormone Therapy Information on:

 

 

 

May 20, 2018 by Joseph Fermin 0 Comments

To Understand the Hormonal Imbalance in Women

To Understand the Hormonal Imbalance in Women

Hormonal Imbalance

Hormonal Imbalance and why can it be so difficult or impossible to clear up acne? As you probably know, you’re hormonal and acne has a vast array of potential causes.

For some people putting cream or simple dietary changes can clear up their skin (Yeah!), but for others, it can be a long and hard arduous journey to clear up.

However, it doesn’t have to be a long struggle for clear skin if you can pinpoint the underlying triggers. Hormonal Imbalance is a cause of acne, and I’m going to talk about the topic in detail so you can understand or have an idea why this can occur, and how you can treat it!

Hormones are abundant when we are young in the body, always involved in complex and far-reaching processes. No Hormonal Imbalance acts in isolation; they work together, so when one is out of balance, it can disrupt the whole endocrine system or worse. This article will discuss Hormonal Imbalance related to pre-menstrual and acne problems.

A brief overview of the menstrual cycle in women and its Hormonal Imbalance, to understand the Hormonal Imbalance in women, it’s essential first to know what hormonal balance is and what should occur ideally.

Your period is a monthly report on your health, and if everything is in balance, you should expect to have an average length cycle, with little-to-no PMS symptoms and a painless period without heavy bleeding. You might be thinking ‘As if that exists?!’ right now, but unfortunately, so many women experience Hormonal Imbalance, stress, nutritional deficiencies, and general ill-health, that things like PMS and period pain have become the norm. PMS is common, but it’s not normal. So, let’s get into it:

Menstrual cycle will starts on the first day of your period bleed, right until the first day of your next period. An average cycle length is anywhere between 23 and 35 days in length and varies from woman to woman. Although the menstrual cycle based on 28 days, Now this is not the case always. Anything outside this 23-35 day cycle length will be considered abnormal or will often indicate a Hormonal Imbalance dysfunction along the line in life.

Hormonal Imbalance

 

There are many hormones involved in the body that can regulate the menstrual cycle, but (so it doesn’t get too confusing!) the main ones are:

  1. Estrogen
  2. Progesterone
  3. Follicle Stimulating Hormone (FSH)
  4. Luteinizing hormone (LH)
  5. Testosterone

Testosterone and other androgens, If implantation of an egg occurs, the above hormones kick in to promote all the requirements for a healthy pregnancy. If fertilization does not happen, after ovulation the uterus lining will shed to make way for a new uterine lining for next ovulation (the body is always hoping!).

Ovulation is meant to occur smack-bang in the middle of your menstrual cycle- at text-book day 14 if you have a 28-day cycle. You will usually get your period 14 days later of ovulation, so if your menstrual cycle is 25 days, you may ovulate on day 11.

The Ovulation shares the menstrual period into two stages: the first phase is when estrogen is the star, and the second stage focuses on progesterone. Progesterone usually is secreted from the ovarian follicle after ovulation (a tiny bit released from your adrenal glands), which develops into a sac called the corpus luteum. Therefore, to have adequate levels of progesterone, you need to have ovulated.

Now, central to the discussion of hormonal balance because many women don’t ovulate every menstrual cycle due to stress, illness, and nutritional inadequacies. Estrogen and progesterone-like to work together in balance, and the ratio between the levels of these hormones is critical. Estrogen is ‘proliferative,’ meaning it promotes cells growth (things like breast and hip development in puberty) and promotes smooth, plump skin, healthy bones, and arteries. Progesterone is ‘secrete,’ meaning that it promotes vascular development and the maintenance of the uterine lining after ovulation.

Hormonal Imbalance

Hormonal Imbalance can occur in women when:

  1. Estrogen levels are high or low, and progesterone is normal
  2. Estrogen levels are high or low, and progesterone is low
  3. Estrogen levels are reasonable, and progesterone levels are low
  4. Pre-Menstrual, Acne, and Estrogen levels
  5. Pre-Menstrual, Acne, and Testosterone levels

Pre-menstrual and acne can occur anywhere in the 1-2 weeks before your period, now this acne is related to the hormonal of a woman’s menstrual period and includes the hormones testosterone, estrogen, progesterone also some androgens and others.

After the ovulation, in the second part of the menstrual cycle the amount of hormones increases, because we know we have testosterone, estrogen, and progesterone. Estrogen will naturally start to decline soon while progesterone begins to rise.

But how do estrogen levels drop?

Too high or too little estrogen can disrupt the menstrual cycle and can impact progesterone levels by impairing ovulation. So, we want estrogen to be at just the right amount- not too high and not too low. Estrogen is broken down (metabolized) through the liver and eliminated via the kidneys and intestines (in your pee and poop). If estrogen is not working or metabolized correctly, then the levels build and build which can result in estrogen excess. Too much estrogen and specific metabolites of estrogen can cause inflammation. Here is where high estrogen levels can trigger pre-menstrual acne.

The cause? Too much re-circulating estrogen and not enough proper liver detoxification going on and extra estrogen can turn in testosterone.

Pre-Menstrual and acne are a sign that your liver needs some love!

Higher amounts of hormones place a higher burden on the liver’s detoxification pathways in the body. Don’t forget! The liver has to metabolize every single thing or substance that enters into our bodies food, environmental toxins, metabolic waste products, red blood cells and much more. It also metabolizes our hormones, especially estrogen (and all the estrogen metabolites).

Some are signs that your liver needs some support or attention:

  1. Headaches and migraines
  2. Constipation
  3. Acne
  4. Eczema
  5. Irritability
  6. PMS
  7. Nausea and indigestion
  8. Sinus congestion (sinusitis, rhinitis)
  9. Allergies
  10. Metabolic syndrome
  11. Insulin resistance

How can you help your liver and make sure you’re eliminating excess hormones?

Make sure you’re pooping at least once per day. If your bowels are congested, this increases your overall toxic load, which has to get processed in the liver.

Eat enough fiber- we require at least 30 grams per day, and many of us reach about half of this. Thread connects into metabolized hormones, cholesterol and moves them out of the body via the intestines. Up your intake of veggies, seeds, beans, legumes, nuts and gluten-free grains.

Cruciferous vegetables contain glucosinolates, which are broken down to indole-3-carbinol. This compound supports the detoxification of estrogens. So eat more broccoli, cauliflower, cabbage, and kale every day.

Eat bitter foods- bitter greens like the rocket (arugula), endive and bitter lettuces stimulate the production of digestive secretions, such bile in the liver. Bile contains metabolized hormones and waste products, so we make sure it leaves the body, so the liver can continually process new fresh bile and help the organization.

Include rosemary and turmeric in your diet as much as possible. This help reduces inflammation in the body, liver and also support detoxification pathways or microbiota.

Make sure you don’t have any hidden food intolerances. These will cause the body inflammation in the GIT and place an extra burden on your liver.

Balance your gut bugs! Your microbiota (intestinal bacteria) also play a significant role in metabolizing of estrogens. Consume fermented foods with each meal: fermented veggies and kombucha, yogurts, kefir, sauerkraut, and feed your bugs with probiotic fibers: green bananas, cold potatoes, whole grains, legumes, fruits, and vegetables.

Acne, Pre-Menstrual, and Progesterone testosterone, and estrogen

Now If your progesterone levels are out of balance, this can also lead to hormonal acne, as other symptoms related to PMS and infertility. Balance progesterone levels have been shown to help block the activity of DHT, and the most potent of androgens, also this present in the skin and contributes to the formation of acne.

We have discussed this earlier in this blog, progesterone mainly produced once ovulation has occurred. The egg released from a structure called the follicle, and once ovulation has occurred, the follicle forms the ‘corpus luteum,’ which is a secretory endocrine structure that produces most of our progesterone.

Progesterone, testosterone, and estrogen work together in a balanced ratio, and when this occurs there will be no more PMS symptoms, fertility will be optimal, and you will feel young. This Issues will arise when a woman fails to ovulate her self, or her body does not have the requirements to maintain and therefore her progesterone, testosterone, and estrogen levels are insufficient.

The reasons why women fail to ovulate and why?

High estrogen levels block the hormonal cascade that triggers ovulation, Polycystic ovarian syndrome (PCOS), Nutritional insufficiency, Low body fat percentage, Stress and Ovarian failure and menopause.

The Insufficient nutrients required to maintain the corpus luteum and produce hormones, Stress, and Inflammation

How can these issues be addressed and ensure we make and maintain progesterone?

We have to ensure to balance our nutritional intake in our body. The corpus luteum requires sufficient levels of magnesium, zinc, iron, B vitamins, vitamin A, vitamin C and iron (for a start).

We also need fats to make our hormones, so it is vital to include healthy fats in your diet. Manage your stress! Stress responses burn through nutrients faster than anything else, so if you chronically stressed you would be depriving your reproductive system of the nutrients, it needs to perform. Stress also inhibits the HPOA axis (hypothalamic-pituitary-ovarian axis). The hypothalamus (a master control center in your brain) needs to convinced that you are safe and nourishing for you to reproduce (which is the ultimate function of your reproductive system).

Acne can associate with insulin resistance and PCOS will primary be due to impaired glucose metabolism, so this is the critical area to address. Insulin promotes androgen production, which is a driving factor in the production of acne. Necessary but effective strategies to combat this include eliminating all refined and added sugar from your diet and eating more protein, fats and complex carbohydrates. Supplementing with chromium, magnesium and B vitamins will also support proper glucose metabolism and insulin function.

December 20, 2017 by Joseph Fermin 0 Comments

How Testosterone Affects Fat Loss: Real Science of Low-T

How Testosterone Affects Fat Loss: Real Science of Low-T

Testosterone Affects Fat Loss, As men age, their testosterone levels decline. This increase in SHBG (sex-hormone binding globulin), which binds to testosterone and thus reduces the amount of free testosterone in the body. Low testosterone levels, obesity, and many other health problems, including fatigue, memory problems and decreased muscle and bone mass. So what is the impact of testosterone on the body and how Testosterone Affects Fat Loss?

Testosterone and energy – low levels of testosterone can cause low energy levels. Regaining natural testosterone levels can increase strength and lead to weight loss. Studies have found that testosterone supplementation reduces total body fat percentages. Obesity is related to low testosterone levels in men. Just as testosterone therapy is associated with decreased obesity, losing weight is associated with increased testosterone levels.

An article in 2014 in the journal of Current Opinion in Endocrinology, Diabetes, and Obesity looked at the existing data regarding testosterone therapy in overweight and obese men with testosterone deficiency (hypogonadism).

  • Many weight loss supplements have dangerous side effects or are ineffective
  • Looked at weight loss, BMI, waist circumference and body composition
  • Evaluated long-term testosterone therapy
  • About 40% of obese nondiabetic men and 50% of overweight diabetic men over 45 have low levels of free testosterone
  • Many studies have found that testosterone therapy in overweight men helps increased lean body mass, weight loss, decreased BMI and reduced waist circumference.
  • Weight loss is significant and sustained with long-term testosterone therapy
  • Testosterone plays a part in protein, fat and carbohydrate metabolism.
  • Testosterone is involved in mitochondrial function and thus energy production and utilization
  • This interference with energy production is likely why those with low testosterone levels experience a lack of energy
  • Testosterone therapy has been found to increase lipid oxidation and normalize glucose use in the body. It was found to increase strength and motivation.

Weight gain associated with an 88% increase in body fat and a 12% increase in lean body mass (LBM) and weight loss with a 72% decrease in body fat and a 28% decrease in LBM.

  • With testosterone therapy, LBM has been shown to increase.
  • Increased LBM means increased energy expenditure at rest
  • Testosterone therapy with improved cardiometabolic function

Testosterone deficiency decrease in energy metabolism from fat and an increase in energy metabolism from glucose.

  • Testosterone therapy has been shown to increase lipid metabolism

Safety? Safety is the primary concern with testosterone replacement therapy. Possible risks discussed in the literature include:

  • Increased risk of prostate and breast cancer
  • Liver toxicity and tumors
  • Sleep apnea exacerbation
  • Testicular infertility and atrophy

Talking with your doctor before starting testosterone injections therapy is necessary.

Summary: If you are a male struggling to lose weight, testosterone therapy is a promising treatment to help with not only weight loss but for body composition, energy levels and overall health.

November 16, 2016 by Joseph Fermin 5 Comments

The Health Benefits Of Raw Cacao

The Benefits Of Raw Cacao

Today’s media is full of reports about so-called “superfoods.” While most of these reports are based on some level of fact, misrepresentation or poor interpretation of medical and scientific findings often leads to misinformation and sensational yet misleading headlines. A prime example of this is raw cacao. The health benefits of raw cacao are astounding; however, this, unfortunately, does not necessarily mean that eating a bar of milk chocolate each day will have the same effects. Read on to learn more about the ways in which raw cacao can improve your health and how to take full advantage.

What is Raw Cacao?

Cacao-based products are made from cacao beans and include cacao powder, nibs, paste, and butter. raw cacao

When purchasing raw cacao products such as powder, it is important to understand the differences between raw cacao powder and the more common cocoa powder. Raw cacao powder is very pure. It is made from raw, unroasted cocoa beans via a process known as cold pressing, which removes the fat in the form of cacao butter; much of the bean and nutrients remain intact.

Cacao is one of the best sources of flavonoids (which are potent antioxidants) available, which means that it has huge health benefits. It is also rich in protein, cholesterol-free and monounsaturated fats, fiber, natural carbohydrates, and minerals (including zinc, iron, potassium, magnesium, copper, manganese, and calcium).

Cocoa powder is produced in a similar way to cacao powder, except that it undergoes high-temperature processing during production. Although it retains significant health benefits, the high temperatures used to destroy some of the nutritional value. As cocoa undergoes further processing to make reduced-strength dark chocolate and milk chocolate, increasing amounts of the nutrients are removed. Therefore, raw cacao powder, cocoa powder, or very strong dark chocolate are recommended for optimal health benefits.

what-is-raw-cacao

Cardiovascular benefits

Many people are at an increased risk of cardiovascular events as they age. The good news is that the consumption of certain foods can help reduce this risk. Cocoa-based products can have significant beneficial effects on the cardiovascular system by reducing cardiovascular risk and atherosclerosis, improving circulation, lowering the levels of LDL (bad) and increasing the levels of HDL (good) cholesterol, and reducing blood pressure. Many of these effects are caused by the anti-inflammatory and antioxidant properties of the flavonoids.

  • Cacao- and cocoa-based products can reduce hypertension. For example, the Cocoa, Cognition, and Aging (CoCoA) Study was performed in 90 elderly individuals who received cocoa-based drinks with high, medium, or low flavonoid content. Blood pressure was reduced significantly in patients that received high- or medium-content cocoa compared with those that received low flavonoid cocoa [1]. The subjects also exhibited improved insulin resistance and reduced lipid peroxidation.
  • Cardiovascular function. A recent study assessed vascular stiffness in healthy younger (<35) and older (50–80) men who drank cocoa or a control drink twice a day for two weeks. The subjects who drank cocoa exhibited significantly improved cardiovascular function, as measured by improved endothelial function, blood pressure, and vascular stiffness [2]. A second similar study confirmed these effects and also indicated that the consumption of high-flavonoid chocolate improved platelet aggregation (an indicator of the ability of the blood to form clots) compared with low flavonoid chocolate [3].
  • Cholesterol. Several studies have investigated the ability of cocoa and cacao to improve cholesterol. For example, consuming 400 g cocoa powder with 500 ml skimmed milk per day increased HDL and lowered LDL cholesterol levels in elderly subjects at high risk of cardiovascular disease [4]. Similar observations were made in young healthy and hypercholesterolemic subjects [5] and in elderly healthy individuals [6].

cacao

Cognitive function

The available data suggest that cocoa and cacao could help protect against cognitive decline in aging individuals.

  • In the same CoCoA study described above, subjects that received cocoa with a high or medium flavonoid content had significant improvements in two different measures of cognitive function: a trail making test and a verbal fluency test. The improvements were greatest in the high flavonoid vs. the intermediate flavonoid group. However, there were no improvements in the mini-mental state evaluation among groups [1].
  • Cocoa and cacao might also protect against dementia and related diseases such as Alzheimer’s disease [7].

Metabolic Effects

The risk of metabolic diseases often increases as we age, and conditions such as diabetes and obesity are associated with reduced mortality. Luckily, cocoa could help reduce the risk of these conditions and their symptoms. Possibly the most important metabolic effect of cocoa is its ability to improve insulin sensitivity. In one study, subjects received dark or white chocolate (with high and zero flavonoid content, respectively), and insulin sensitivity was assessed using glucose tolerance tests and the quantitative insulin sensitivity check index. Dark, but not white, chocolate significantly improved both measures of insulin sensitivity and reduced blood pressure [8].

Hormonal Changes

The symptoms of many aging-related diseases have been linked to reduced hormone levels over time. Therefore, improving natural hormone production can reduce the symptoms of many aging-related diseases. Cocoa can have beneficial effects on the production of several hormones.

  • Testosterone Injections. Cocoa and cacao contain high concentrations of zinc, which has been shown to increase testosterone production [9].
  • Stress hormones. We all know that nice, relaxed feeling that occurs when we eat a delicious, rich piece of dark chocolate. It turns out that there is a physiological reason for this! Cocoa can potently inhibit the release of the stress hormone cortisol. Healthy men aged 20–50 who consumed a single piece of dark chocolate had a significantly reduced response to a psychosocial stressor. These effects were caused by inhibiting the release of the stress hormones cortisol and epinephrine from the adrenal gland [10].

So, there you have it! Cocoa really is a super-food. It is not only delicious but, when eaten in unprocessed forms, it has significant health benefits.

Testosterone Injections – Curious about testosterone injections Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698

References

[1] D. Mastroiacovo, C. Kwik-Uribe, D. Grassi, S. Necozione, A. Raffaele, L. Pistacchio, R. Righetti, R. Locale, M.C. Lechiara, C. Marini, C. Ferri, G. Desideri, Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging (CoCoA) Study–a randomized controlled trial, The American journal of clinical nutrition, 101 (2015) 538-548.

[2] C. Heiss, R. Sansone, H. Karimi, M. Krabbe, D. Schuler, A. Rodriguez-Mateos, T. Kraemer, M.M. Cortese-Krott, G.G. Kuhnle, J.P. Spencer, H. Schroeter, M.W. Marx, M. Kelm, Impact of cocoa flavanol intake on age-dependent vascular stiffness in healthy men: a randomized, controlled, double-masked trial, Age (Dordrecht, Netherlands), 37 (2015) 9794.

[3] G. Rull, Z.N. Mohd-Zain, J. Shiel, M.H. Lundberg, D.J. Collier, A. Johnston, T.D. Warner, R. Corder, Effects of high flavanol dark chocolate on cardiovascular function and platelet aggregation, Vascular Pharmacology, 71 (2015) 70-78.

[4] N. Khan, M. Monagas, C. Andres-Lacueva, R. Casas, M. Urpi-Sarda, R.M. Lamuela-Raventos, R. Estruch, Regular consumption of cocoa powder with milk increases HDL cholesterol and reduces oxidized LDL levels in subjects at high-risk of cardiovascular disease, Nutrition, metabolism, and cardiovascular diseases : NMCD, 22 (2012) 1046-1053.

[5] S. Martinez-Lopez, B. Sarria, J.L. Sierra-Cinos, L. Goya, R. Mateos, L. Bravo, Realistic intake of a flavanol-rich soluble cocoa product increases HDL-cholesterol without inducing anthropometric changes in healthy and moderately hypercholesterolemic subjects, Food & function, 5 (2014) 364-374.

[6] N. Neufingerl, Y.E. Zebregs, E.A. Schuring, E.A. Trautwein, Effect of cocoa and theobromine consumption on serum HDL-cholesterol concentrations: a randomized controlled trial, The American journal of clinical nutrition, 97 (2013) 1201-1209.

[7] L. Dubner, J. Wang, L. Ho, L. Ward, G.M. Pasinetti, Recommendations for Development of New Standardized Forms of Cocoa Breeds and Cocoa Extract Processing for the Prevention of Alzheimer’s Disease: Role of Cocoa in Promotion of Cognitive Resilience and Healthy Brain Aging, Journal of Alzheimer’s disease : JAD, 48 (2015) 879-889.

[8] D. Grassi, C. Lippi, S. Necozione, G. Desideri, C. Ferri, Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons, The American journal of clinical nutrition, 81 (2005) 611-614.

[9] C.D. Hunt, P.E. Johnson, J. Herbel, L.K. Mullen, Effects of dietary zinc depletion on seminal volume and zinc loss, serum testosterone concentrations, and sperm morphology in young men, The American journal of clinical nutrition, 56 (1992) 148-157.

[10] P.H. Wirtz, R. von Kanel, R.E. Meister, A. Arpagaus, S. Treichler, U. Kuebler, S. Huber, U. Ehlert, Dark chocolate intake buffers stress reactivity in humans, Journal of the American College of Cardiology, 63 (2014) 2297-2299.

August 29, 2016 by admin 0 Comments

Natural Eggshell Membrane (NEM)

Natural Eggshell Membrane (NEM)

Natural eggshell membrane

Natural Eggshell Membrane: The membrane film on the inside of an eggshell is made of the exact ingredients that human joints are made of. It is a true, natural source of hyaluronic acid, glucosamine, and chondroitin. People with osteoarthritis (knee and joint stiffness) have seen amazing results from this new alternative to joint and tendon management. In fact, many have been able to get off pain medications completely once they started using NEM on a continual basis, after only a considerably short period. Customary treatments for osteoarthritis primarily attempt to focus on the symptoms (pain, discomfort, and inflammation) related to the disease. For the most part, this involves the use of anti-inflammatory drugs, analgesics, and COX-2 inhibitors. Most arthritis drugs have negative side effects. There are natural alternatives that are proving to be unexpectedly effective. Most importantly, they come with no negative side effects. Currently, the most prevalent are called “Natural Eggshell Membrane” (NEM).

Case Studies on NEM

  • There was a study in clinical intervention in aging that was done related to the eggshell membrane. It appears, NEM has the Natural eggshell membraneability to reduce symptoms of osteoarthritis significantly and was shown superior to glucosamine and chondroitin. Another clinical trial performed with humans, 37 of them having osteoarthritis, showed that taking 500 mg of NEM daily resulted in a considerable decrease in pain in 7 to 30 days. [1]
  • In a more extensive study, 39 patients received 500 mg of NEM, once daily, for 30 days. After only seven days, patients described an improvement in flexibility of 27.8%. After thirty days, a 43.7% improvement in flexibility was denoted. These percentages are based on Ontario and McMaster University’s osteoarthritis index. After a month, the average reduction in general pain was 72.5%. [2] This is magnificent news for suffering patients.

Find 100% Natural Eggshell Membrane

Screen Shot 2016-08-29 at 10.52.02 AMThere is a special brand that contains only real NEM. The maker is Membrell. The product is called “Joint Health®”, and the reviews on it are spectacular. Again, it contains only 100% natural eggshell membrane. Ginger and Cherries contain high amounts of anti-inflammatory phytochemicals. These can eliminate pain for gout and arthritis sufferers. However, and most impressively, no food actually rebuilds cartilage, except natural eggshell membrane (NEM). Consider that the most popular joint/arthritis supplements are glucosamine and chondroitin, with sales nearing $1 billion annually.

What Makes NEM Unique?

For starters, Glucosamine is extracted from the shell of shrimp, crab, and lobster. Moreover, chondroitin sulfate is derived from animal cartilage. An example would be sharks. Eggshell membrane is made by separating the actual membrane from the eggshell. The eggshell membrane, once isolated, is partially hydrolyzed and dry-blended. Patients with an egg allergy should avoid taking this supplement.

Natural eggshell membraneNatural eggshell membrane

Animal Age Too, You Know?

There have been marvelous studies yielding positive results on retired racing horses. Most impressively, Membrell also produces a medication that is particularly useful for dogs suffering from arthritis. We get asked about arthritis for pets all the time so, it is great to hear they have made dosages especially geared towards dogs. Maybe, we will get into anti-aging for pets some day. That would be awesome!

AAI Rejuvenation Clinic

If you have any questions or comments or are interested in beginning a testosterone therapy or hGH therapy contact us. We even have Sermorelin therapy for our more committed patients. You can fill out our short form or call us directly:

 

Case Studies

[1] Ruff KJ, DeVore DP, Leu MD, Robinson MA “Eggshell membrane: a possible new natural therapeutic for joint and connective tissue disorders. Results from two open-label human clinical studies.” Clin Interv Aging. 2009; 4: 235 -40

[2] Ruff KJ, Winkler A, Jackon RW, DeVore DP, Ritz BW “Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled clinical study.” Clin Rheumatol. 2009 Aug; 28(8):907-14.