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December 14, 2018 by Joseph Fermin 0 Comments

What is Ibutamoren MK-677 and The Benefits 5 (2)

What is Ibutamoren MK-677 and The Benefits

Ibutamoren MK-677 and the all-news online and forums are talking about Ibutamoren and for the properties to help athletes recover faster and used by those patients wishing to increase their growth hormone. However, clinical studies of this compound Ibutamoren are relative, So far, Ibutamoren (also known as MK-677), and promotes the secretion of the growth hormone (GH), and increases insulin-like growth factor (IGF-1) Levels.

Ibutamoren MK-677 increases the growth hormone levels by mimicking the action of the hormone ghrelin and binding the ghrelin receptors (GHSR) in the brain. The activated (GHSR) stimulates growth hormone release from the brain, (GHSR) found in brain regions that control appetite, mood, pleasure, biological rhythms, memory, and cognition. Therefore, we can expect ibutamoren MK-677 may also affect these functions. The clinical studies describe only the effects ibutamoren MK-677 has on appetite.

The great thing about ibutamoren MK-677 increases with little or no efforts the growth hormone levels. Also, help such as cortisol levels: cortisol help suppress the immune system to heal faster and impairs the learning and memory.

Uses Of Ibutamoren MK-677

Ibutamoren MK-677

Building Muscle:

Ibutamoren MK-677 is frequently used as an anabolic substance, to increase lean body mass, and create muscle. It is orally active also and can be taken once a day. These are all full benefits compared to other growth hormone stimulators.

As previously mentioned, ibutamoren MK-677 increases growth hormone levels and the (IGF-1). Both growth hormone and (IGF-1), and it help increase muscle mass, muscle strength, and reduce body fat In obese patients, a two-month treatment (DB-RCT) with ibutamoren MK-677 increased lean mass, and transiently increased basal metabolic rate (BMR).

Muscle Wasting and Strength:

In a study done (DB-RCT) in eight patients healthy volunteers and where food-deprived, and ibutamoren MK-677 reversed the diet-induced protein loss and helped with the muscle wasting patients. In a study 123 elderly patients with hip fracture, ibutamoren improved gait speed, muscle strength and reduced the number of falls (RCT).

Bone Density and Healing:

Growth hormone (GH) increases bone healing and eventually bone density. Now because of the increased turnover in treated patients with growth hormone. Patients under the therapy over (1 year) to see the bone density increase, and in 24 volunteers with healthy obese patients, ibutamoren MK-677 increased the bone turnover (DB-RCT).

The study on 187 elderly Patients, Ibutamoren MK-677, increased bone building, measured by osteocalcin on bone turnover in multiple studies (3 DB-RCTs). In one study (DB-RCT), In 292 women patients with post-menopausal. Ibutamoren MK-677 has increased bone mineral density which helps improve bone strength and prevent osteoporosis and more.

Better Quality Sleep Duration:

A study on (DB-PCT) showed that in both younger and elderly patients, ibutamoren MK-677 improved sleep quality and Rapid Eye Movement (REM), and sleep duration, apart from scientific studies done, there have been many reports, across various forums online.

Now can’t perform your best in the weight room or the boardroom without great and better sleep by Biohacking Insomnia.

Longevity Benefits:

Growth Hormone Secretion (GHS) and muscle mass both decline around mid-puberty throughout life, In a study with 65 senior men and women (DB-RCT), THE daily ibutamoren MK-677 increased Growth Hormones and (IGF-1) levels without serious adverse effects. Now the (IGF-1) is known to have beneficial effects on longevity.

Memory Enhancement Effects:

Ibutamoren MK 677 increases (IGF-1), which is known to enhance memory and learning, Ibutamoren MK-677 also increases (REM) sleep duration and quality. Understand that sleep is essential for proper cognitive function, A study (DB-multicenter) questioned the association of low (IGF-1) and Alzheimer’s, and whether ibutamoren MK 677 could be of help. However, in this study, ibutamoren MK-677 was ineffective at slowing the progression of Alzheimer’s in Patients.

Growth Hormone Deficiency:

Ibutamoren MK 677 can increase growth hormone, (IGF-1), levels in children with growth hormone deficiency. Furthermore, these effects change the concentrations of prolactin, triiodothyronine (T3), thyroxine (T4), thyrotropin, glucose, cortisol, and insulin.

In severe men with GH deficiency Ibutamoren MK 677 increased (IGF-1) and growth hormone, with no changes in cortisol, PRL, and thyroid hormone levels. However, insulin and glucose increased (DB-RCT).

Tissue Regeneration and Wound Healing:

Growth hormone (GH) increases tissue regeneration and wound healing so that ibutamoren MK 677 may help with these. There are individual reports of ibutamoren being helpful, but scientific studies are lacking.

April 23, 2018 by Joseph Fermin 0 Comments

What are The Benefits of Sermorelin Acetate & GHRP’s 5 (1)

What are The Benefits of Sermorelin Acetate
Ipamorelin and GHRP’s

Sermorelin Acetate is a release of growth hormone results in the liver, releasing IGF1 explained in this article. Sermorelin therapy is a continuous anti-aging therapy.

By the age of 30, Human growth hormone production begins to declining for both women and men at about 1% per each year. Sermorelin is not HGH, Sermorelin is a peptide comprised of the first 29 amino acids of endogenous (growth hormone releasing peptide) This peptide will stimulate the body to produces more Human growth hormone, and now widely used.

What are The Benefits of Sermorelin Acetate

WHAT IS SERMORELIN ACETATE

Sermorelin acetate is a natural biologically active analog of growth hormone releasing factor (GRF 1-44) which is a growth hormone-releasing (GHR) that is naturally released by the brain to stimulate the production of growth hormone (GH) by the pituitary.

Sermorelin it is a growth hormone secretagogue and is not a human growth hormone; which means that it stimulates the pituitary gland by binding to specific receptors to increase the production and secretion of GH.

Growth hormone-releasing hormone (GHRH) produced so that the pituitary gland can provide the body with sufficient growth hormone to sustain health, vitality and otherwise rational aspects of human form and function. While aging, GHRH declines causing reduced production and secretion of pituitary HGH and thereby increasing growth hormone insufficiencies that erode health, stamina, and vitality in later life.

This therapy which stimulates the pituitary gland to produce the increased natural secretion of human growth hormone (HGH). Since Sermorelin acetate has been approving safe in children, to increase their production of growth hormone, it is considered safe for use in improving the natural production of growth hormone in adults deficient in growth hormone. Each person’s individual needs are used to determine to dose.

BENEFITS OF GHRP-2

GHRP-2 is a synthetic analog of the peptide hormone ghrelin. Ghrelin is a small 28 amino acid peptide that is produced by the stomach in response to hunger. It also activates the growth hormone secretagogue receptor (also known as the ghrelin receptor) to stimulate GH production and metabolism. GHRP-2 functions similarly to stimulate the hypothalamus and increase the production of endogenous GH from the pituitary gland; synthesis then slowly drops back to baseline by the third hour after administration. This more closely replicates the pulsatile nature of endogenous GH production, which makes it advantageous and potentially safer compared with synthetic HGH use.

BENEFITS OF GHRP-6

GHRP-6 is a hexapeptide synthetic analog of met-enkephalin, which is an endogenous opioid growth factor; however, GHRP-6 does not exhibit opioid activity. GHRP-6 works similarly to GHRP-2; however, it is a first-generation GHRP that does not induce GH levels as strongly as GHRP-2. Instead, it promotes food intake by stimulating hunger and helps increase energy metabolism; therefore, it is good for patients that need to increase their food intake.

BENEFITS OF SERMORELIN THERAPY:

The Sermorelin Therapy consists of Sermorelin to stimulates the pituitary gland to produce the increased natural secretion of human growth hormone. The benefits of Sermorelin helps the pituitary by inspiring production and flow of the participant’s natural Growth Hormone. Here a list of benefits from a Growth Hormone therapy such as GHRP’s, Sermorelin and Ipamorelin:

  • Month 1:

• Increased energy overall
• Restful sleep and Deeper sleep
• Improved state of mind and stamina

  • Month 2:

• Reduced belly fat
• Improved metabolism
• The return of some muscle tone
• Improved skin tone and fewer wrinkles
• Stronger hair and nails

  • Month 3:

• Increased mental focus
• Improved flexibility and joint health
• More feelings of drive and ambition
• Enhanced sex drive and performance

  • Month 4:

• Improved mental acuity
• Better skin and elasticity
• Improved appearance, the hair, and nails
• weight loss and muscle mass

  • Month 5:

• Continued loss of belly fat, and Noticeably fuller, healthier hair
• Improved skin tone with the reduced appearance of wrinkles

  • Month 6:

• A 5–10% reduction in body fat, without diet or exercise
• A 10% increase in lean muscle mass, Improved physique
• Increased vitality dies to organ regrowth (vital organs, including the brain, shrink with age)

 

AAI Rejuvenation Clinic

 

(more…)

April 27, 2017 by Joseph Fermin 2 Comments

What is Sermorelin also was known as GHRP2-GHRP6 5 (1)

What is Sermorelin GHRP2-GHRP6 Benefits

Testosterone Therapy, GHRP, GHRP2-GHRP6

GHRP2-GHRP6 also was known as Sermorelin, is a growth hormone-releasing hormone (GHRH) analog used as a diagnostic agent. It is a 29-amino acid polypeptide representing the 1–29 fragment from endogenous human GHRH and is thought to be the shortest fully functional fragment of GHRH. It is used as a diagnostic agent to assess growth hormone (GH) secretion.

Sermorelin GHRP2-GHRP6 is a combination of human growth hormone-releasing peptides.

These medications stimulate the production of a hormone in the human brain that stimulates the body to produce its own Human Growth Hormone by the pituitary gland.

GHRPs are a group of peptides mimicking natural hypothalamic proteins, which promote the release of Human Growth Hormone (HGH) by the pituitary.

GHRP2 and GHRP6 work synergistically with Sermorelin to boost hypothalamic function, thereby stimulating the pituitary gland to increase production of the body’s own endogenous HGH and to robustly increase IGF-1 levels.

Sermorelin Acetate GHRP2 and GHRP6 are dispensed as a sterile lyophilized powder which must be reconstituted prior to subcutaneous injection. Reconstitution and handling of Sermorelin Acetate GHRP2-GHRP6 must be performed per instructions of the prescribing physician.

GHRPs

Growth hormone-releasing peptides (GHRPs) are a family of synthetic peptides that stimulate GH secretion. Importantly, they have no structural similarity to sermorelin or GHRH; instead, they function via receptors in the pituitary gland and/or hypothalamus. At AAI Rejuvenation Clinic, we compound two different GHRPs (GHRP2-GHRP6) into the Sermorelin mixture. The resulting mixtures, Sermorelin peptides GHRP2 and Sermorelin peptides GHRP6, are particularly potent and effective GH-inducing agents that yield comparable results to typical yet considerably more expensive HGH therapy.

GHRP-2

GHRP-2 is a synthetic analog of the peptide hormone ghrelin. Ghrelin is a small 28 amino acid peptide that is produced by the stomach in response to hunger. It also activates the growth hormone secretagogue receptor (also known as the ghrelin receptor) to stimulate GH production and metabolism. GHRP-2 functions similarly to stimulate the hypothalamus and increase the production of endogenous GH from the pituitary gland; synthesis then slowly drops back to baseline by the third hour after administration. This more closely replicates the pulsatile nature of endogenous GH production, which makes it advantageous and potentially safer compared with synthetic HGH use.

GHRP6

GHRP-6 is a hexapeptide synthetic analog of met-enkephalin, which is an endogenous opioid growth factor; however, GHRP-6 does not exhibit opioid activity. GHRP-6 works similarly to GHRP-2; however, it is a first-generation GHRP that does not induce GH levels as strongly as GHRP-2. Instead, it promotes food intake by stimulating hunger and helps increase energy metabolism; therefore, it is good for patients that need to increase their food intake.

Sermorelin Injection – Curious about Benefits of Sermorelin Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698.

Benefits:

01) Increase IGF-1 levels and secretion of Human Growth Hormone
02) Anti-Aging Effect, Improving
03) Libido and Sexual Stamina
04) Physical Performance
05) Immune Function
06) Muscle Mass
07) The decrease in Body Fat
08) Skin Elasticity
09) Improves sleep quality
10) Assists in recovery from traumatic injuries
11) Improves eyesight and vision
12) Reduces liver uptake of glucose.
13) Promotes liver gluconeogenesis

Sermorelin Therapy Information

January 27, 2016 by Joseph Fermin 0 Comments

Where Does hGH Come From? 5 (2)

What is Human Growth Hormone?
Where Does hGH Come From?

What is human Growth hormone? Well, let’s start with the basics: Growth Hormone is the master hormone released by the pituitary gland. This peptide hormone is made up of 191 amino acids that form a long, single-chain polypeptide. Growth hormone is synthesized in the somatotropic cells, which, again, are found in the anterior pituitary gland. These cells are also responsible for storing and releasing the hormone. Growth hormone is a peptide hormone that stimulates growth, development, and regeneration. The pituitary gland is the master gland of the endocrine system. It controls all the glands of the endocrine system. Your hormones keep your entire body and all its systems functioning. Hormones impact your weight, hair, and nails, as well as sex drive and attitude. It’s essential to know your hormone levels and whether they are in the normal range. You should also be aware of how they affect you and what you can do to ensure they are functioning optimally.

Sermorelin acetate is a natural active analog of growth hormone releasing factor, (GHR) which is a growth hormone-releasing. (Sermorelin) Is naturally releaser to stimulate production healthily by the pituitary gland. Sermorelin Therapy is not a human growth hormone, it is a hormone secretagogue, which means that it stimulates the pituitary gland to specific receptors to increase the production of HGH.

Growth hormone-releasing peptides (GHRPs) are a family of synthetic peptides that stimulate GH secretion. Importantly, they have no structural similarity to sermorelin or GHRH; instead, they function via receptors in the pituitary gland and/or hypothalamus. At AAI Rejuvenation Clinic, we compound two different GHRPs (GHRP-2 and GHRP-6) into the sermorelin mixture. The resulting mixtures, sermorelin peptides GHRP2 and sermorelin peptides GHRP6, are particularly potent and effective GH-inducing agents that yield comparable results to typical yet considerably more expensive hGH therapy.

GHRP-2 is a synthetic analog of the peptide hormone ghrelin. Ghrelin is a small 28 amino acid peptide that is produced by the stomach in response to hunger. It also activates the growth hormone secretagogue receptor (also known as the ghrelin receptor) to stimulate GH production and metabolism. GHRP-2 functions similarly to stimulate the hypothalamus and increase the production of endogenous GH from the pituitary gland; synthesis then slowly drops back to baseline by the third hour after administration. This more closely replicates the pulsatile nature of endogenous GH production, which makes it advantageous and potentially safer compared with synthetic HGH use.

GHRP-6 is a hexapeptide synthetic analog of met-enkephalin, which is an endogenous opioid growth factor; however, GHRP-6 does not exhibit opioid activity. GHRP-6 works similarly to GHRP-2; however, it is a first-generation GHRP that does not induce GH levels as strongly as GHRP-2. Instead, it promotes food intake by stimulating hunger and helps increase energy metabolism; therefore, it is good for patients that need to increase their food intake.

Our interest is to help answer the question, what is human Growth Hormone, in as simple and concise a format while making sure no important details are missed. Simply put, Growth Hormone, as is encompassed in the name, literally helped to grow you; every aspect of you. When growth hormone is released, it is metabolized by the liver and converted into what is known as IGF-1 (Insulin Growth Factor-1). This chemical invites the production of protein in the body and depending on your different stages of development, promotes the growth of your muscles, bones as well as all your organs. In fact, Growth Hormone is responsible for the growth of all the tissue in your body. It promotes the regeneration and production of cells in the body, as well as stimulates their healing.

HGH is produced by top pharmaceutical organizations as a bio-identical hormone. This is identical to what the body produces with the exception that there is no DNA association. Administering hGH therapy in the not-so-distant-past was nothing to take lightly. It needed to be extracted from the brain of cadavers. This antiquated process didn’t come without its unfortunate repercussions. Patients treated with this early form of hGH had abstract side effects. This process is no longer legal. Today, technology has advanced to the point that we are able to clone and produce a clean, exact, bio-identical replica of the HGH hormone in a laboratory. When you qualify for therapy with AAI Rejuvenation Clinic, you will be prescribed Brand hGH only. HGH cannot be produced in a simple lab. It cannot be compounded or cannot be ingested, as the molecule is too delicate and small. It would be immediately destroyed by the gastric process. Contact us at AAI Clinics so we can talk to you about how to know if you are obtaining real hGH or, how to qualify for this life-transforming program.

 

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**NOTE**  The content contained in this blog is subject to interpretation and is the opinion of the content writer.  We do not claim it to be fact.  We encourage you to consult a medical doctor before taking any prescribed medications or supplements.

November 16, 2015 by Joseph Fermin 0 Comments

Sermorelin Peptides GHRP and Benefits of HGH 5 (1)

Sermorelin Peptides GHRP and Benefits of HGH

Sermorelin peptides GHRP and benefits of hGH are undeniable. However, when using injectable exogenous HGH (GH not produced naturally by our body) our bodies go from producing low amounts of GH to essentially producing no GH. The reason this occurs is that the body becomes completely dependent on the exogenous hGH. As incredible as it is to have higher levels of GH in your body, it’s extremely important to cater to the health of your pituitary gland to ensure long-term health and positive results. So how do you get your pituitary gland to start working again? More importantly, how do you get it to work harder and more efficiently for an individual your age or with your particular abnormal pituitary condition? This is a job for Sermorelin peptide GHRP peptides.

Sermorelin Acetate, sermorelin, sermorelin therapy

Sermorelin

  • Sermorelin peptides (GHRH) is a bio-identical hormone that has recently been genetically engineered to stimulate the secretion of Growth Hormone releasing hormone from the hypothalamus. GHRH is a peptide that contains the first 29 amino acids of the 191 in GH. It is GHRH that stimulates your pituitary gland to release GH. As we age, hormone production in the pituitary gland declines. It has been proven that HGRH can restore the production levels of the pituitary causing significant elevation of IGF-1.

Peptides

  1. One of the major functions of peptides is to work as hormones because these are a specific type of peptide responsible for carrying signals between cells and glands. These peptides will control blood sugar regulation, sleep, and other body functions. They are created by the liver, intestine, stomach, kidneys and endocrine glands. Common peptides found in hormones include oxytocins, gastrins, bradykinins, human growth hormone and insulin.
  2. – The brain produces neuropeptides, which you find in neural tissue. They are an extension of your neuro system throughout your body, meaning that they act as regulators and signals in various processes triggered from locations within the brain. One example of neuropeptides would be endorphins.
  3. – Alkaloids are another type of peptide and they are commonly involved in developing defense mechanisms in small animals, plants, and fungi. Examples of these peptides include dynorphin, panda mini, and ergotamine.
  4. – When peptides work as antibiotics, they prevent microorganisms from growing within the body. This is an example of using peptides side effects to kill bacteria that cause diseases as antibiotics are commonly used in medicine.
  5. – The peptide can help support our body. This is because when peptide chains become long enough, it will form proteins, which are used as building blocks of animal and human bodies. Keratin is a perfect example as this protein is in human nails and hair and animal claws, hooves, scales, feathers, and horns. Collagen is another protein created from peptides and is found in bones, tooth enamel, ligaments, and tendons.

GHRP’s

  • GHRP’s are a small family of peptides acting in the hypophyseal portal system to release Growth Hormone (GH). There are two main forms of GHRP, which will be depicted further below, that are compounded into the Sermorelin Peptides GHRP mixture. The end result, Sermorelin GHRP2 or Sermorelin GHRP6, is an especially potent and effective Growth Hormone inducing agent that can generate comparable results to a typical, yet considerably more costly, hGH therapy protocol.

GHRP2

  • Growth-Hormone-Releasing-Peptide-Two (GHRP2) is a synthetic ghrelin analogue. It stimulates the hypothalamus and critically increases the natural production of Growth Hormone (GH) from the pituitary gland, which slowly drops back to baseline levels by the third hour after administration. This more closely replicates the natural pulse of GH in the human body, giving it an advantage over synthetic HGH use

– GHRP-2 (also known as KP 102) is a synthetic hexapeptide Growth Hormone Releasing Peptide (GHRP) which acts on the hypothalamus and the pituitary gland to release growth hormone with a slight stimulatory effect on Prolactin, ACTH, and Cortisol levels.

– GHRP-2 is considered to be a true hGH secretagogue, meaning that it stimulates the body’s own secretion of hGH. Human Growth hormone has been shown in studieshttps://www.aaiclinics.com/treatments/hgh-therapy/what-is-human-growth-hormone/ to promote lean body mass and reduce adiposity (fat).

– GHRP2 has demonstrated that it is very effective at stimulating GH production in research test subjects.

– It has a short half-life with peak concentrations occurring around 15 minutes and not longer than 60 minutes after administration.

– GHRP-2 is a 2nd generation GHRP just behind GHRP-6. Compared to GHRP-6, GHRP-2 is considered to be much more superior in terms of growth hormone stimulation because over longer periods of time it maintains maximum elevations in Growth Hormone.

– GHRP-2 has shown to increase IGF-1 levels (Insulin-like Growth Factor-1), and even greater results happen when used with Sermorelin Peptides GHRP (Growth Hormone Releasing Hormone – GHRH). It has a short half-life with peak concentrations occurring around 15 minutes but not longer than 60 minutes. The response of natural physiologic system includes the increase in levels of calcium ion influx alongside with increased release of growth hormones in response to the high-amplitude pulsation from the GHRP-2.

– GHRP-2 and other ghrelin analogues increase the number of somatotropes involved in the GH pulse by inhibiting somatostatin, GHRH increases the pulse amplitude per pituitary cell or somatotrope by other means.

-Unlike ghrelin, GHRP-2 is not lipogenic which means that it does not induce fat storage. Although ghrelin plays a large role in hunger, GHRP-2 as an analog of ghrelin does not increase appetite significantly.

GHRP6

  • Growth-Hormone-Releasing-Peptide-Six (GHRP6) is a Growth Hormone (GH) secretagogue. The Peptide GHRP-6 works similarly to GHRP-2, however, it is a Hexapeptide that promotes food intake by stimulating hunger and helps increase energy metabolism.

Growth Hormone Releasing Peptides, similar to GHRP-6, are most commonly used for the treatment of Growth Hormone (GH) deficiencies, eating disorders, etc.

– Researchers discovered that those GH-Releasing Peptides (specifically GHRP-6 & GHRP-2) followed a mode of action, which bound them to and was mediated through receptors different from those for GHRH.

– Researchers discovered that these GH-Releasing Peptides acted synergistically with the natural human Growth Hormone Releasing Hormone (GHRH), which is related to Sermorelin Peptides GHRP, in both laboratory animals and humans to produce large releases of Growth Hormone.

– In the 1980s, the first highly potent GH-Releasing peptide, GHRP-6, was developed. Due to a strong GH release response from the peptide, it became the first member of a class called Growth Hormone Secretagogues.

– GHRP-6 is believed to be acting naturally on both pituitary and hypothalamic sites (Fairhall et al. 1995). In a time-dependent and dose-dependent manner, the primary pituitary cells of rats were demonstrated on.

  • Both GHRP-2 and GHRP-6 have great benefit and potential. Studies have shown them to be effective in treating age-related GH decline when used in combination with Sermorelin (GHRH).

GHRP’s when used in equal dosages of GHRH creates a 3-hour pulse of GH that is double the amplitude of 8IU of synthetic GH, resulting in:

a) increased energy

b) improved sleep

c) increased lean body mass

d) decreased body fat

e) increased collagen production and

f) increased healing capability.

These factors not only make it more effective but actually a healthier substitute to Exogenous Growth Hormone.

Overview: Sermorelin Peptides,
Sermorelin GHRP2 & 6 Peptides

Use of Sermorelin usually improves sleep within the first few weeks of therapy. This is usually concurrent with increased energy levels and improved mood. After 3-6 months of therapy, patients start reporting noticeable or significant body changes, such as the increase in muscle tone and leaner physique. Over time patients will also notice a significant improvement in skin tone and health. Like most peptide hormones, Sermorelin Peptides GHRP usually has a loading period of 3-6 months before full effects are noticed. Once injected, both Sermorelin Peptides GHRP are eliminated very quickly from the body and therefore need to be injected frequently. Its actions are dependent on a chain reaction of biological processes which result in elevated and sustained HGH and growth factors.

When considering Growth Hormone Therapy, personal preference and disposition are always the determining factors. However, Sermorelin Peptides GHRPs is a wonderful option to getting you back your vitality and youth.

Contact us at your earliest convenience so we can give you more information about how HGH therapy and/or Sermorelin therapy can make a difference in your health. We look forward to helping you decide which replacement therapy is best for you. AAI Rejuvenation Clinic’s anti-aging professionals are your resource source to extend your life and get more from it.

Sermorelin Injection – Curious about Benefits of Sermorelin Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698

WHAT IS SERMORELIN?

September 20, 2015 by Joseph Fermin 0 Comments

SERMORELIN GHRP 2 5 (1)

SERMORELIN GHRP 2

GHRP 2 is a Growth Hormone Releasing Peptide Two (GHRP2) is a synthetic ghrelin secretagogue. It stimulates the hypothalamus and critically increases the natural production of Growth Hormone (GH) from the pituitary gland, which slowly drops back to baseline levels by the third hour after administration. This more closely replicates the natural pulse of GH in the human body, giving it an advantage over synthetic hGH use.

Testosterone Enanthate, Testosterone Enanthate Description, Low Testosterone in Women's

  • GHRP-2 (also known as KP 102) is a synthetic hexapeptide Growth Hormone Releasing Peptide (GHRP) which acts on the hypothalamus and the pituitary gland to release growth hormone with a slight stimulatory effect on Prolactin, ACTH, and Cortisol levels.
  • GHRP-2 is considered to be a true hGH secretagogue, meaning that it stimulates the body’s own secretion of hGH. Human Growth hormone has been shown in studies to promote lean body mass and reduce adiposity (fat).
  • GHRP2 has demonstrated that it is very effective at stimulating GH production in research test subjects.
  • It has a short half-life with peak concentrations occurring around 15 minutes and not longer than 60 minutes after administration.
  • GHRP-2 is a 2nd generation GHRP just behind GHRP-6. Compared to GHRP-6, GHRP-2 is considered to be much more superior in terms of growth hormone stimulation because over longer periods of time it maintains maximum elevations in Growth Hormone.
  • GHRP-2 has shown to increase IGF-1 levels (Insulin-like Growth Factor-1), and even greater results happen when used with Sermorelin (Growth Hormone Releasing Hormone – GHRH). It has a short half-life with peak concentrations occurring around 15 minutes but not longer than 60 minutes. The response of natural physiologic system includes the increase in levels of calcium ion influx alongside with increased release of growth hormones in response to the high-amplitude pulsation from the GHRP-2.
  •  GHRP-2 and other ghrelin secretagogue increase the number of somatotropes involved in the GH pulse by inhibiting somatostatin, GHRH increases the pulse amplitude per pituitary cell or somatotrope by other means.
  • Unlike ghrelin, GHRP-2 is not lipogenic which means that it does not induce fat storage. Although ghrelin plays a large role in hunger, GHRP-2 as a secretagogue ghrelin does not increase appetite significantly.

Sermorelin Injection – Curious about Benefits of Sermorelin Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698

WHAT IS SERMORELIN?

**NOTE**  The content contained in this blog is subject to interpretation and is the opinion of the content writer.  We do not claim it to be fact.  We encourage you to consult a medical doctor before taking any prescribed medications or supplements.

September 20, 2015 by Joseph Fermin 0 Comments

SERMORELIN GHRP 6 5 (1)

SERMORELIN GHRP 6

GHRP 6 Growth Hormone Releasing Peptide Six (GHRP6) is a Growth Hormone (GH) secretagogue. The Peptide GHRP-6 works similarly to GHRP-2, however, it is a Hexapeptide that promotes food intake by stimulating hunger and helps increase energy metabolism.

  • Growth Hormone Releasing Peptides, similar to GHRP-6, are most commonly used for the treatment of Growth Hormone (GH) deficiencies, eating disorders, etc.
  • Researchers discovered that those GH-Releasing Peptides (specifically GHRP-6GHRP-2) followed a mode of action, which bound them to and was mediated through receptors different from those for GHRH.
  • Researchers discovered that these GH-Releasing Peptides acted synergistically with the natural hormone Growth Hormone Releasing Hormone (GHRH), which is related to Sermorelin, in both laboratory animals and humans to produce large releases of Growth Hormone.
  • In the 1980s, the first highly potent GH-Releasing peptide, GHRP-6, was developed. Due to a strong GH release response from the peptide, it became the first member of a class called Growth Hormone secretagogues.
  • GHRP-6 is believed to be acting naturally on both pituitary and hypothalamic sites (Fairhall et al. 1995). In a time-dependent and dose-dependent manner, the primary pituitary cells of rats were demonstrated on.

Both GHRP-2 and GHRP-6 have great benefit and potential. Studies have shown them to be effective in treating age-related GH decline when used in combination with Sermorelin (GHRH).

  • GHRP’s when used in equal dosages of GHRH creates a 3-hour pulse of GH that is double the amplitude of 8IU of synthetic GH, resulting in:

a) increased energy

b) improved sleep

c) increased lean body mass

d) decreased body fat

e) increased collagen production and

f) increased healing capability.

These factors not only make it more effective but actually a healthier substitute to exogenous Growth Hormone.

If you have any questions or comments related to this information or if you are interested in more details about the requirements for therapy qualification, don’t hesitate to fill out our Medical History Form. Once you do, you will be contacted within 24 business hours by one of our friendly wellness advisors.

Sermorelin Injection – Curious about Benefits of Sermorelin Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698

WHAT IS SERMORELIN?

**NOTE**  The content contained in this blog is subject to interpretation and is the opinion of the content writer.  We do not claim it to be fact.  We encourage you to consult a medical doctor before taking any prescribed medications or supplements.

September 20, 2015 by Joseph Fermin 0 Comments

The Protocol Sermorelin Therapy vs HGH Therapy 5 (1)

Protocol Sermorelin Therapy

Protocol Sermorelin therapy, We reiterate that there is no one-protocol-fits-all when it comes to any kind of hormone therapy. Be warned: if you are speaking to an organization that is offering you solid quotes before their doctors have had an opportunity to review your file details, you should be very weary. It doesn’t mean that they cannot legally obtain medication for you. It simply implies your health is not at the forefront of that transaction. In fact, it’s most possible, that is all your communication is to that organization; a transaction.

Your protocol needs to be individualized based on your complete health history and file characteristics. That being said, there are certain similarities from one protocol to the next and certainly, there are some particular characteristics that all subcutaneous protocols have in common.

The following information is not to be used in substitution or in combination with anything that your prescribing physician has organized for you. The information below is only to be regarded as educational and generally suggestive when relating to subcutaneous Protocol Sermorelin therapy. When you have been prescribed a Sermorelin or Growth Hormone program, your doctor should explain to you:

  • the areas where you will inject the medication
  • exact time and day you should be administering your medicine
  • how to handle and store the medication
  • information about needles and all pertinent supplies in order to properly and effectively administer your program.

Other important points to consider when on a physician supervised Sermorelin protocol:

  • You must not eat or drink anything but water 90 minutes before or after your Protocol Sermorelin Therapy administration. Sermorelin impacts your insulin levels. Food does the same thing. Eating food in close proximity to your Sermorelin administration will surely null and void that injection.
  • Sermorelin should not be administered during the day. The reaction of Sermorelin to effectively focus and work on the pituitary, hypothalamus, serotonin levels and related areas of the brain actually promotes a sleepy reaction that can be inhibiting for participants during the day. Because Sermorelin so actively works on the pituitary to stimulate secretion, it induces a sense for needed rest that is difficult to combat.
  • Sermorelin is known to stimulate hunger in an effort to produce the resources and energy necessary to effectively metabolize your produced GH into IGF-1 which is needed to promote the protein synthesis required to generate the benefits expected from a GH therapy.
  • Sermorelin should be injected subcutaneously. Your best option is to administer Sermorelin directly into fat. Injecting Sermorelin into muscle will cause the medication to be hyper-metabolized. If you inject it into fat, it is processed much more slowly, extending the half-life of your administration. Conversely, if you inject Sermorelin directly into your muscle, it is much more quickly metabolized and processed by the body so its functionality/effectiveness time is reduced.
  • Because Sermorelin serves as a stimulant to the pituitary and hypothalamus, it actually helps to regenerate and rejuvenate the glands, promoting their health and efficiency. For this reason, it is safe and recommended to administer Sermorelin on a 7-night administration weekly cycle. Because Sermorelin is inducing production of your own GH and it’s forcing maximum secretion of your involved glands, it’s best to be very consistent with this therapy, especially when aiming to achieve results reflective of a much more expensive, straight bio-identical HGH protocol.

The protocol for Sermorelin is really a simple one. Retrospectively, despite Sermorelin also being a Growth Hormone therapy, promoting the same results as an HGH program in participants with a well-functioning pituitary, they administration times are quite opposite.

Remember:

  • HGH must be administered in the day-time. The intention is to inject this medication when it will least interfere with the body’s natural production of Growth Hormone. Our endocrine system is most active at nighttime and this holds particularly true for the secretion period for Growth Hormone. Growth Hormone is released during several different phases of the day. However, the majority of the Growth Hormone your body is going to benefit from is released at night, during REM sleep (deepest, most restful sleep stage). If you administer hGH at night time, it will interfere with your natural production of GH, as your body checks all your blood levels constantly to determine if any given secretion is required to normalize and maintain normal bodily function. When the body detects that GH levels are normal (resulting from the HGH administration), it will signal the brain to not produce any additional GH. Extended hGH therapy on this improper protocol will most certainly cause atrophy of the pituitary from lack of use.
  • Conversely, Protocol Sermorelin Therapy does not promote an artificial elevation of GH levels. As a secretagogue, it actually induces your own production of Growth Hormone. The GH surge in your body is all-natural; your own. It is not a man-made or bio-identical hormone. It is real, DNA associated Growth Hormone secreted by the pituitary and hypothalamus as stimulated by the administration of Sermorelin. For this very reason, the opposite is true regarding the appropriate time to administer protocol Sermorelin therapy on your required administration days.
  • The smartest thing any GH therapy participant could do is consider a complete, well-rounded protocol inclusive of both Sermorelin and HGH at the same time. Of course, the dosages would be tweaked to ensure there isn’t an exaggerated overall dose of GH for the body to deal with at any one given time. Depending on the patient’s goals and file details, the Sermorelin/hGH combination therapy can be structured in a wide variety of effective ways. Combining HGH and Sermorelin is also a significantly effective way to participate in a leveler impacting the program like hGH without having to deal with the much higher costs of an only HGH hormone replacement program.

Typically, what dosage would somebody of my height, weight, and age be prescribed for HGH therapy?

 It’s imperative to understand that no one should ever generalize a program for you. It’s crucial that your prescribing physician takes into account all of your file details, health history, and personal goals before structuring a Sermorelin protocol, as we will do for you here at AAI Rejuvenation Clinic.

Beyond that clarification, statistically:

  • A person weighing between 100lbs -140lbs, between 4.5 – 5ft tall, would be prescribed 200mcg of Sermorelin every evening before bed.
  • A person weighing between 141lbs -165lbs, between 5 – 5.8ft tall, would be prescribed 250mcg of Sermorelin every evening before bed.
  • A person weighing between 166lbs -195lbs, between 5.5 – 6ft tall, would be prescribed 250 – 300mcg of Sermorelin every evening before bed.
  • A person weighing between 196lbs – more, between 5.5 – or taller, would typically be prescribed 300mcg or more, as determined by the physician, of Sermorelin every evening before bed.

Side Note: Elderly people and women will be prescribed higher dosages than outlined above to stimulate the kind of GH production needed to achieve the desired benefits and results depicted in these educational sites.

Combination HGH and Sermorelin Protocol

The more common ‘combination protocols will significantly very in dosing, as this is an art your prescribing physician needs to be well acquainted with in order to promote safe and effective results while keeping unwanted side effects at bay. At AAI Rejuvenation Clinic, our physicians are experts in the field of hormone replacement therapy and qualified by the Anti-Aging Association board.

A program can look something like this:

For someone that is very receptive to therapy, that doesn’t need as much, they may only need Sermorelin on the weekend.

  • Sat and Sun.

This ensures they are getting a healthy dose of GH elevation 7 days a week without putting the health of their pituitary at stake.

  • There is also the case in which your physician, in an effort to maximize your IGF-1 levels to expedite the physiological response to therapy whilst still keeping unwanted side effects at bay, may significantly reduce your hGH administration in the morning  but intelligently substitute the additional GH supplementation through the introduction of natural Growth Hormone via the selected AAI physician secretagogue, either Sermorelin GHRP2 or Sermorelin GHRP6, every evening in addition. Usually, still, hGH is not administered on a 7 consecutive day basis.

Patients needing the benefits of Growth Hormone that wish to participate in hGH therapy but are restricted by the costs may consider a combination protocol that entails either a much lower dosage of hGH during the day (allowing them to need much fewer vials of the hGH to complete their program) while substituting their GH elevation requirements for the day by introducing Protocol Sermorelin Therapy in the evening as well. This not only assists in providing an effective and potent GH enriching program but, at the same time, it’s a protocol that strategically caters to the health of the pituitary by inducing its work to secrete GH regardless of the current levels due to therapy. This ensures the participant of this protocol never has to worry about atrophy of the pituitary. In fact, this participant can rest assured they are on a well-rounded program that is intended to maximize their health benefits while minimizing any unwanted side effects.

Again, we reiterate that the details above are statistically depicted and there is no chart for dosing an effective and safe Sermorelin protocol. However, the above chart most accurately represents, statistically, what a patient of a certain height, age and weight can expect to be prescribed for a safe and effective Protocol Sermorelin therapy program.

Sermorelin Injection – Curious about Benefits of Sermorelin Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698

WHAT IS SERMORELIN?

**NOTE**  The content contained in this blog is subject to interpretation and is the opinion of the content writer.  We do not claim it to be fact.  We encourage you to consult a medical doctor before taking any prescribed medications or supplements.

September 19, 2015 by Joseph Fermin 0 Comments

Sermorelin Side Effects & Common Treatment 5 (1)

SERMORELIN SIDE EFFECTS

Sermorelin Side effects, Patients have been known to develop anti- GRF antibodies at least once during treatment with Sermorelin. The significance of these antibodies is not clear and often a positive test at one growth assessment will become negative by the next assessment. The presence of antibodies doesn’t seem to affect growth or appear to be related to a specific adverse reaction profile. No generalized allergic reactions to Sermorelin have been reported.

Many patients on sermorelin therapy have developed anti-GHRH antibodies at least once during treatment. However, the significance and long-term effects of these antibodies are unclear, and a positive test is often only temporary. The presence of these antibodies does not appear to lead to specific adverse effects or modulate growth.

No generalized allergic reactions to Side effects of Sermorelin have been reported. The most common treatment-related adverse event (occurring in approximately one in six patients) is a local injection site reaction, which usually presents as redness, pain, or swelling. The injection site reaction can sometimes be serious; for example, of the 350 patients treated with sermorelin in a clinical trial, three discontinued therapies because of these injection site reactions. Other treatment-related adverse events were rare, with an incidence of <1%, and included hives, headache, sleepiness, flushing, dysphagia, dizziness, and hyperactivity.

There is little evidence to suggest that sermorelin is associated with any drug abuse or dependence and there have been no reports of this from clinical trials.

The most common treatment-related adverse event (occurring in about 1 patient in 6) is local injection reaction characterized by pain, swelling or redness. Of 350 patients exposed to Sermorelin in clinical trials, three discontinued therapy due to injection reactions. Other treatment-related adverse events had individual occurrence rates of less than 1% and include a headache, flushing, dysphagia, dizziness, hyperactivity, somnolence, and urticaria.

When administered intravenously for diagnostic use, the following adverse reactions have been noted: flushing of the face, injection site pain, redness and/or swelling, nausea, headache, vomiting, dysgeusia, pallor and tightness in the chest.

WHAT IS SERMORELIN?

Drug Abuse and Dependence

The clinical pharmacology suggests that Sermorelin is very unlikely to be associated with drug abuse or dependence and there have been no reports of this from clinical trials.

*information available through RxList (drug index)

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September 19, 2015 by Joseph Fermin 0 Comments

What Can I Expect from Sermorelin Injection? 5 (1)

What Can I Expect from Sermorelin Injections

Sermorelin Injections Therapy, what can I expect from it? We can actually make this very, very simple. Sermorelin IS an hGH therapy. Participating in Sermorelin therapy results in the manifestation of the same exact results that entice a patient to partake in an hGH therapy. The goal is to elevate Growth Hormone levels, which in turn raises IGF-1 levels. The only difference is administering hGH is the direct infusion of the synthesized GH agent while injecting Sermorelin only incites your own production of GH.

This fact actually makes Sermorelin injections much safer to take, as it is stimulating your own, natural production of the hormone. The process serves to stimulate and rejuvenate the pituitary. Conversely, HGH therapy can cause atrophy of the pituitary if it’s improperly administered and interferes with normal GH production periods.

The receptivity of the body to the therapy is also greatly increased. Because Sermorelin stimulates normal Growth Hormone release patterns, it is occurring in its natural, pulsating fashion. As a result, it enters the blood stream as is most prevalently bioavailable and can help promote better results while keeping any side effects even further away.

Let us look at a chart detailing what can be expected during the first six months of Sermorelin therapy:

Sermorelin Injections Therapy

Our website is full of bullet points outlining as simple and concise as possible the basic, statistically recorded benefits experienced by patients studied on hormone therapy around the world. We wanted to dedicate the below section to actual patients of AAI that have been through an AAI physician organized Sermorelin protocol. The experiences below have been specifically requested by our AAI Wellness Advisors to each individual patient and approved by him or her to put on this page. Of course, the names have been changed to protect their privacy. The comments have been minimally edited to focus on relevancy. To help you answer the question: What can I expect from Sermorelin injections therapy?

  • Mark Schultz – NC – (…) but it’s cool that the doctor didn’t give me a hard time about just wanting to do hGH instead of the other stuff (Sermorelin). I just really didn’t think it’d be as good. I was told a lot that hGH was just stronger and was gonna give me better results so, if I was going to spend my money, I need it to be effective. I still want to thank you though _____, for insisting that I get permission from the doctor to just give it a try. The good thing is since I tried the other stuff (hGH) first I could actually compare it (…). Three months into this stuff (Sermorelin) and I’ve only seen more and better physical results. I actually lost 6 pounds in the first 10 days so, I’m happy. Cool stuff _____. You’re a good man.
  • Sabrina Wilson – TX – Oh, I’m so happy to write this out for you _____. Thank you for asking. I’ve been telling all my friends actually. I just wanted to lose a few pounds, remember like I told you? Well, though, I was a little discouraged at first. Because I thought it wasn’t working. But you were right. (…) after those few couple of weeks, everything just started changing. I spoke with Dr. Larry about it b/c I swear it’s just been helping me with all my other hormones. I can just feel it, you know what I mean? (…)
  • Mary Correa – FL – (…) absolutely everything you told me it I could expect. I’m telling you I was losing myself. When a person can’t sleep for x number of days in a row something bad starts to happen to ya. So, like I told you 8 days, 2 hours a day, I was having trouble just spelling my name. So that first day that I took the Sermorelin injections and I actually knocked out and stayed knocked out, that was some $#@&! You guys better never go anywhere!!!!
  • Javier Gonzalez – GA– I knew about it because of my field (…) it’s discussed around me a lot. Most of the time you hear about the hard stuff and you don’t even know where these people are getting it from so when the doc really broke it down for me, I figured for the price I should try it. I gotta tell you, totally unexpected. You know they tell you-you gotta wait some weeks and (…) but I felt this the NEXT day. I slept so good man I was just ready the next day. Alert! I’ve been telling my buddy (…) so you guys better hook me up when he calls you. Ha!
  • Gina Carrano – (FL) – (…) and I’ve been telling her how much it is worked to [help my libido]. She wanted me to share with her to see how she felt I told her I don’t think so! Lol. Aside from that, you were right. I don’t feel like the old lady at the gym anymore and I definitely don’t need to wait 3 days in between that cycling class anymore. By the next day, I’m myself again and can push harder. Thank you for that. You don’t know what it feels like to start NOTICING that you are getting old. it sucks.

Sermorelin Injection – Curious about Benefits of Sermorelin Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698

WHAT IS SERMORELIN?

**NOTE**  The content contained in this blog is subject to interpretation and is the opinion of the content writer.  We do not claim it to be fact.  We encourage you to consult a medical doctor before taking any prescribed medications or supplements.