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November 30, 2016 by Joseph Fermin 1 Comment

The Relationship Between Hormones and Stress

Hormones and Stress

Hormones and Stress in the holiday season are upon us! Although this can a wonderful time filled with love and laughter, it can also significantly increase the day-to-day stresses experienced by many people; this can easily turn into chronic stress. Did you know that chronic stress can have a significant impact on your normal hormonal responses? Read on to learn more about the effects stress can have on your body and what you can do about it.

Hormones and Stress

The Hormones and Stress feeling that we all know so well is part of the body’s normal response to a real or perceived threat. However, your body does not differentiate between serious physical threats and “normal” pressures, and so a heavy workload or demands from your family can build up over time and have a detrimental effect on your health.

The stress response is commonly known as the “fight or flight” response, and it begins in the brain. When a stress is perceived, the amygdala sends a signal to the hypothalamus, which activates the sympathetic nervous system and triggers the release of adrenaline from the adrenal glands into the bloodstream. Adrenaline then accelerates the heartbeat to pump more blood to the muscles in preparation for “flight.” In addition, the pulse, blood pressure, and breathing rate all increase to enhance the amount of oxygen inhaled. Other senses, such as sight and hearing, become sharper.

The Normal Stress Response

 

During the second phase of the stress response, the hypothalamus releases corticotropin-releasing hormone (CRH), which stimulates the release of adrenocorticotropic hormone (ACTH). ACTH then stimulates the release of cortisol from the adrenal glands, which ensures that the body remains on “high alert.” Cortisol levels remain elevated until the threat passes; the stress response is then shut down once the brain perceives that the threat is no longer there (http://www.health.harvard.edu/staying-healthy/understanding-the-stress-response).

Hormones and Stress

The Effects of Stress

Prolonged periods of stress prevent the shut-down of the normal stress response because the body remains on high-alert and producing cortisol. The long-term exposure to cortisol and other Hormones and Stress has a number of negative effects throughout the body, including:

  1. In the respiratory system, the accelerated breathing rate could lead to asthma or panic attacks (http://www.apa.org/helpcenter/stress-body.aspx).
  2. In the cardiovascular system, prolonged periods of an elevated heart rate and increased blood pressure can increase the risk of cardiovascular disease, heart attack, and stroke.
  3. In the liver, the increased levels of cortisol stimulate the production of glucose in anticipation of increased energy demands. Such prolonged exposure to elevated blood glucose levels might increase the risk of metabolic syndrome and type 2 diabetes.
  4. Some animal studies have suggested that chronic stress can reduce testosterone levels and sperm production and maturation in men; it can even lead to erectile dysfunction and impotence.
  5. In women, chronic stress can lead to an irregular menstrual cycle, worsened premenstrual syndrome symptoms, and reduced libido.
  6. Stress can also dampen the immune system.
  7. Emotionally, stress can affect your sleep, increase irritability, anxiety, and depression, and reduce concentration.

How to Reduce the Effects of Stress

There is no need to worry: there is a lot you can do to counteract the natural stress responses that occur at this time of year. It is important to understand what makes you stressed, as well as what makes you relax. For example, there are several lifestyle changes that can help reduce stress (http://www.webmd.com/balance/stress-management/stress-management-relieving-stress):

  1. Take time out to do something you enjoy
  2. Express your feelings
  3. Use relaxation techniques such as meditation
  4. Exercise regularly; exercise is one of the best ways of reducing stress

Because many of the symptoms of chronic stress are also associated with low hormones, such as sleep loss, fatigue, and low testosterone levels, we recommend getting your Hormones and Stress levels checked if you experience any prolonged, unusual or unexplained stress. At AAI Clinic, we can measure your Hormones, Testosterone Injections, and Stress and make recommendations regarding any hormone replacement therapy or supplements that could alleviate your stress-related symptoms.

Testosterone Injections – Curious about testosterone injections Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-LowT (5698)

References

  1. Golbidi, S., J.C. Frisbee, and I. Laher, Chronic stress impacts the cardiovascular system: animal models and clinical outcomes. Am J Physiol Heart Circ Physiol, 2015. 308(12): p. H1476-98.
  2. Bergmann, N., F. Gyntelberg, and J. Faber, The appraisal of chronic stress and the development of the metabolic syndrome: a systematic review of prospective cohort studies. Endocr Connect, 2014. 3(2): p. R55-80.
  3. Kalaitzidou, I., et al., Stress management and erectile dysfunction: a pilot comparative study. Andrologia, 2014. 46(6): p. 698-702.
  4. Gannon, L., et al., Perimenstrual symptoms: relationships with chronic stress and selected lifestyle variables. Behav Med, 1989. 15(4): p. 149-59.
  5. Golkar, A., et al., The Influence of Work-Related Chronic Stress on the Regulation of Emotion and on Functional Connectivity in the Brain. PLoS ONE, 2014. 9(9): p. e104550.

November 16, 2016 by Joseph Fermin 5 Comments

The Health Benefits Of Raw Cacao

The Benefits Of Raw Cacao

Today’s media is full of reports about so-called “superfoods.” While most of these reports are based on some level of fact, misrepresentation or poor interpretation of medical and scientific findings often leads to misinformation and sensational yet misleading headlines. A prime example of this is raw cacao. The health benefits of raw cacao are astounding; however, this, unfortunately, does not necessarily mean that eating a bar of milk chocolate each day will have the same effects. Read on to learn more about the ways in which raw cacao can improve your health and how to take full advantage.

What is Raw Cacao?

Cacao-based products are made from cacao beans and include cacao powder, nibs, paste, and butter. raw cacao

When purchasing raw cacao products such as powder, it is important to understand the differences between raw cacao powder and the more common cocoa powder. Raw cacao powder is very pure. It is made from raw, unroasted cocoa beans via a process known as cold pressing, which removes the fat in the form of cacao butter; much of the bean and nutrients remain intact.

Cacao is one of the best sources of flavonoids (which are potent antioxidants) available, which means that it has huge health benefits. It is also rich in protein, cholesterol-free and monounsaturated fats, fiber, natural carbohydrates, and minerals (including zinc, iron, potassium, magnesium, copper, manganese, and calcium).

Cocoa powder is produced in a similar way to cacao powder, except that it undergoes high-temperature processing during production. Although it retains significant health benefits, the high temperatures used to destroy some of the nutritional value. As cocoa undergoes further processing to make reduced-strength dark chocolate and milk chocolate, increasing amounts of the nutrients are removed. Therefore, raw cacao powder, cocoa powder, or very strong dark chocolate are recommended for optimal health benefits.

what-is-raw-cacao

Cardiovascular benefits

Many people are at an increased risk of cardiovascular events as they age. The good news is that the consumption of certain foods can help reduce this risk. Cocoa-based products can have significant beneficial effects on the cardiovascular system by reducing cardiovascular risk and atherosclerosis, improving circulation, lowering the levels of LDL (bad) and increasing the levels of HDL (good) cholesterol, and reducing blood pressure. Many of these effects are caused by the anti-inflammatory and antioxidant properties of the flavonoids.

  • Cacao- and cocoa-based products can reduce hypertension. For example, the Cocoa, Cognition, and Aging (CoCoA) Study was performed in 90 elderly individuals who received cocoa-based drinks with high, medium, or low flavonoid content. Blood pressure was reduced significantly in patients that received high- or medium-content cocoa compared with those that received low flavonoid cocoa [1]. The subjects also exhibited improved insulin resistance and reduced lipid peroxidation.
  • Cardiovascular function. A recent study assessed vascular stiffness in healthy younger (<35) and older (50–80) men who drank cocoa or a control drink twice a day for two weeks. The subjects who drank cocoa exhibited significantly improved cardiovascular function, as measured by improved endothelial function, blood pressure, and vascular stiffness [2]. A second similar study confirmed these effects and also indicated that the consumption of high-flavonoid chocolate improved platelet aggregation (an indicator of the ability of the blood to form clots) compared with low flavonoid chocolate [3].
  • Cholesterol. Several studies have investigated the ability of cocoa and cacao to improve cholesterol. For example, consuming 400 g cocoa powder with 500 ml skimmed milk per day increased HDL and lowered LDL cholesterol levels in elderly subjects at high risk of cardiovascular disease [4]. Similar observations were made in young healthy and hypercholesterolemic subjects [5] and in elderly healthy individuals [6].

cacao

Cognitive function

The available data suggest that cocoa and cacao could help protect against cognitive decline in aging individuals.

  • In the same CoCoA study described above, subjects that received cocoa with a high or medium flavonoid content had significant improvements in two different measures of cognitive function: a trail making test and a verbal fluency test. The improvements were greatest in the high flavonoid vs. the intermediate flavonoid group. However, there were no improvements in the mini-mental state evaluation among groups [1].
  • Cocoa and cacao might also protect against dementia and related diseases such as Alzheimer’s disease [7].

Metabolic Effects

The risk of metabolic diseases often increases as we age, and conditions such as diabetes and obesity are associated with reduced mortality. Luckily, cocoa could help reduce the risk of these conditions and their symptoms. Possibly the most important metabolic effect of cocoa is its ability to improve insulin sensitivity. In one study, subjects received dark or white chocolate (with high and zero flavonoid content, respectively), and insulin sensitivity was assessed using glucose tolerance tests and the quantitative insulin sensitivity check index. Dark, but not white, chocolate significantly improved both measures of insulin sensitivity and reduced blood pressure [8].

Hormonal Changes

The symptoms of many aging-related diseases have been linked to reduced hormone levels over time. Therefore, improving natural hormone production can reduce the symptoms of many aging-related diseases. Cocoa can have beneficial effects on the production of several hormones.

  • Testosterone Injections. Cocoa and cacao contain high concentrations of zinc, which has been shown to increase testosterone production [9].
  • Stress hormones. We all know that nice, relaxed feeling that occurs when we eat a delicious, rich piece of dark chocolate. It turns out that there is a physiological reason for this! Cocoa can potently inhibit the release of the stress hormone cortisol. Healthy men aged 20–50 who consumed a single piece of dark chocolate had a significantly reduced response to a psychosocial stressor. These effects were caused by inhibiting the release of the stress hormones cortisol and epinephrine from the adrenal gland [10].

So, there you have it! Cocoa really is a super-food. It is not only delicious but, when eaten in unprocessed forms, it has significant health benefits.

Testosterone Injections – Curious about testosterone injections Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698

References

[1] D. Mastroiacovo, C. Kwik-Uribe, D. Grassi, S. Necozione, A. Raffaele, L. Pistacchio, R. Righetti, R. Locale, M.C. Lechiara, C. Marini, C. Ferri, G. Desideri, Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging (CoCoA) Study–a randomized controlled trial, The American journal of clinical nutrition, 101 (2015) 538-548.

[2] C. Heiss, R. Sansone, H. Karimi, M. Krabbe, D. Schuler, A. Rodriguez-Mateos, T. Kraemer, M.M. Cortese-Krott, G.G. Kuhnle, J.P. Spencer, H. Schroeter, M.W. Marx, M. Kelm, Impact of cocoa flavanol intake on age-dependent vascular stiffness in healthy men: a randomized, controlled, double-masked trial, Age (Dordrecht, Netherlands), 37 (2015) 9794.

[3] G. Rull, Z.N. Mohd-Zain, J. Shiel, M.H. Lundberg, D.J. Collier, A. Johnston, T.D. Warner, R. Corder, Effects of high flavanol dark chocolate on cardiovascular function and platelet aggregation, Vascular Pharmacology, 71 (2015) 70-78.

[4] N. Khan, M. Monagas, C. Andres-Lacueva, R. Casas, M. Urpi-Sarda, R.M. Lamuela-Raventos, R. Estruch, Regular consumption of cocoa powder with milk increases HDL cholesterol and reduces oxidized LDL levels in subjects at high-risk of cardiovascular disease, Nutrition, metabolism, and cardiovascular diseases : NMCD, 22 (2012) 1046-1053.

[5] S. Martinez-Lopez, B. Sarria, J.L. Sierra-Cinos, L. Goya, R. Mateos, L. Bravo, Realistic intake of a flavanol-rich soluble cocoa product increases HDL-cholesterol without inducing anthropometric changes in healthy and moderately hypercholesterolemic subjects, Food & function, 5 (2014) 364-374.

[6] N. Neufingerl, Y.E. Zebregs, E.A. Schuring, E.A. Trautwein, Effect of cocoa and theobromine consumption on serum HDL-cholesterol concentrations: a randomized controlled trial, The American journal of clinical nutrition, 97 (2013) 1201-1209.

[7] L. Dubner, J. Wang, L. Ho, L. Ward, G.M. Pasinetti, Recommendations for Development of New Standardized Forms of Cocoa Breeds and Cocoa Extract Processing for the Prevention of Alzheimer’s Disease: Role of Cocoa in Promotion of Cognitive Resilience and Healthy Brain Aging, Journal of Alzheimer’s disease : JAD, 48 (2015) 879-889.

[8] D. Grassi, C. Lippi, S. Necozione, G. Desideri, C. Ferri, Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons, The American journal of clinical nutrition, 81 (2005) 611-614.

[9] C.D. Hunt, P.E. Johnson, J. Herbel, L.K. Mullen, Effects of dietary zinc depletion on seminal volume and zinc loss, serum testosterone concentrations, and sperm morphology in young men, The American journal of clinical nutrition, 56 (1992) 148-157.

[10] P.H. Wirtz, R. von Kanel, R.E. Meister, A. Arpagaus, S. Treichler, U. Kuebler, S. Huber, U. Ehlert, Dark chocolate intake buffers stress reactivity in humans, Journal of the American College of Cardiology, 63 (2014) 2297-2299.

November 8, 2016 by Joseph Fermin 6 Comments

What are the Symptoms of Peri-menopause

What is the Peri-menopause?

As women, our bodies go through dramatic changes as we age, and these changes are caused by our hormones. Perimenopause is the time of a woman’s life when her hormonal cycle slows, her fertility reduces, and periods become less common as she heads toward menopause. It can be a very stressful time because it affects her physical and emotional state.

To understand what causes the peri-menopause and how to best reduce the symptoms, it is important to appreciate the changes that occur in the female body during aging. There are four main stages in a woman’s hormonal life:

Puberty

Puberty is the process of sexual maturation; it normally begins around the age of 11 and lasts for several years. Generally, it begins with breast development, followed by the growth of pubic hair and finally menstruation.

The Reproductive Years

The reproductive years begin with the onset of menstruation and persist until peri-menopause. They are characterized by the menstrual cycle, which controls a woman’s fertility. The menstrual cycle is primarily governed by fluctuations in the levels of the hormones that control ovulation and regulate the thickness of the uterine lining to prepare for the implantation of a possible fertilized egg.

  • The hypothalamus secretes gonadotropin hormone-releasing hormone (GnRH), which stimulates the pituitary gland to release follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
  • FSH stimulates follicles in the ovaries to prepare an egg for maturation and release, which includes the secretion of estrogen to prepare the uterus for implantation.
  • LH triggers ovulation, or the release of an egg from the ovaries, which results in the production and release of progesterone and additional estrogen to prepare the body for fertilization and pregnancy [1].

Menopause

Perimenopause

Perimenopause occurs when a woman’s hormonal cycle transitions toward menopause and infertility begin. It often starts in women in their late-40’s and can last for up to 11 years; the average duration is ~4 years. During the peri-menopause, menses become less common and the symptoms typically associated with menopause (discussed below) begin.

The changes that occur during menopause are caused by altered hormone levels. A woman remains fertile only as long as her ovaries produce and secrete eggs via a process known as ovulation. Since there are a finite number of eggs, female fertility essentially has an expiration date. The production of estrogen and progesterone relies upon ovulation, which means that hormone production is diminished significantly once eggs are no longer released.

Hormonally, the peri-menopause is defined by persistently increased LH and FSH levels and very low estrogen and progesterone levels. Testosterone secretion can also decline by approximately 50% during peri-menopause [2].

Menopause

Menopause officially starts one year after a woman’s last period. Menopausal women produce very high levels of FSH but low levels of estrogen and progesterone. They are no longer fertile and are at a higher risk of diseases such as osteoporosis and cardiovascular disease because of the reduced hormone concentrations [3].perimenopause

What are the Symptoms of Peri-Menopause?

The most common symptoms of peri-menopause (http://www.webmd.com/menopause/guide-perimenopause#2) are:

  • Hot flashes
  • Reduced sex drive
  • Discomfort and dryness during sex
  • Fatigue
  • Problems sleeping
  • Mood swings
  • Migraines
  • Severe premenstrual syndrome
  • Irregular periods
  • Breast tenderness
  • An urgent need to urinate
  • Urine leakage, particularly when sneezing or coughing

Because some of these symptoms can be caused by other hormone-related conditions, we always recommend getting your hormone levels checked to ensure that you receive an accurate diagnosis. If you visit AAI Rejuvenation Clinic with the above symptoms, we will measure the levels of your sex hormones as part of our work up. This will allow us to develop a specific program to make you feel like your old self.

Alleviate Your Symptoms with Hormone-Replacement Therapy (HRT)

Unfortunately, the transition from fertility to menopause is part of natural aging and it happens to all women. Although the symptoms of perimenopause can be severe, it is possible to reduce their severity and be able to function fully.

For many years, HRT was used to alleviate the symptoms of peri-menopause and reduce the risk of mortality, dementia, cardiovascular disease, and osteoporosis in aging women. Although a now-revised link to an increased risk of breast cancer led to a temporary decline in the use of HRT, it is again the number one treatment and disease-prevention strategy used in peri-menopausal and menopausal women [4].

As the name suggests, the aim of HRT is to replace the hormones no longer being produced naturally. The hormones are often delivered in tablet form, although transdermal Testosterone Patches, creams, Testosterone Gels, and implants can also be used. There are four major forms of HRT:

  • Estrogen alone
  • Estrogen and progesterone
  • Gonadomimetics, which contain estrogen, progesterone, and testosterone; an example is a tibolone
  • SERMs (selective estrogen receptor modulators)

Because HRT can restore your hormone levels to those you experienced when you were young, it can relieve your symptoms and also reduce the risk of diseases associated with low hormone levels such as osteoporosis and cardiovascular disease. Although some studies have suggested that HRT could protect against stroke, diabetes, cognitive aging, and mood, these effects are more controversial [5]. Nevertheless, the clinical evidence supporting the beneficial effects of HRT in cardiovascular disease and osteoporosis is convincing:

  • HRT reduces the risk of cardiovascular diseases. An evidence-based study investigated the evidence from randomized clinical trials and concluded that HRT could reduce the risk of mortality and cardiovascular disease in women within 10 years of the menopause aged <60 years [5]. However, there is evidence that HRT should be avoided in older women because it might increase the risk of coronary events [6].
  • HRT reduces the risk of osteoporosis. One of the best-known benefits of HRT is its ability to inhibit bone loss and reduce the incidence of fractures in perimenopausal women; estrogen therapy might be more effective than combined estrogen-progesterone treatment [7].

In addition to these clinical effects, HRT alleviates the symptoms of peri-menopause including skin and hair complaints and sexual symptoms [8], as well as hot flashes [9].

Measure your hormone levels today and find out if HRT could improve your day-to-day life.

References

  • [1] R.E. Jones, K.H. Lopez, Human reproductive biology, Academic Press2006.
  • [2] S.J. Richardson, The biological basis of the menopause, Bailliere’s clinical endocrinology and metabolism, 7 (1993) 1-16.
  • [3] L. Jia, H. Jin, J. Zhou, L. Chen, Y. Lu, Y. Ming, Y. Yu, A potential anti-tumor herbal medicine, Corilagin, inhibits ovarian cancer cell growth through blocking the TGF-beta signaling pathways, BMC complementary, and alternative medicine, 13 (2013) 33.
  • [4] R.A. Lobo, J.H. Pickar, J.C. Stevenson, W.J. Mack, H.N. Hodis, Back to the future: Hormone replacement therapy as part of a prevention strategy for women at the onset of menopause, Atherosclerosis, 254 (2016) 282-290.
  • [5] R. Sood, S.S. Faubion, C.L. Kuhle, J.M. Thielen, L.T. Shuster, Prescribing menopausal hormone therapy: an evidence-based approach, International Journal of Women’s Health, 6 (2014) 47-57.
  • [6] R.A. Lobo, Where are we 10 years after the Women’s Health Initiative?, The Journal of clinical endocrinology and metabolism, 98 (2013) 1771-1780.
  • [7] The 2012 hormone therapy position statement of The North American Menopause Society, Menopause (New York, N.Y.), 19 (2012) 257-271.
  • [8] D. Rouskova, K. Mittmann, U. Schumacher, H. Dietrich, T. Zimmermann, Effectiveness, tolerability and acceptance of an oral estradiol/levonorgestrel formulation for the treatment of menopausal complaints: a non-interventional observational study over six cycles of 28 days, Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 30 (2014) 712-716.
  • [9] N. Santoro, C.N. Epperson, S.B. Mathews, Menopausal Symptoms and Their Management, Endocrinology and metabolism clinics of North America, 44 (2015) 497-515.

November 2, 2016 by Joseph Fermin 2 Comments

The Importance of Exercise

 

Exercise is Important why? 

Exercise, As humans, we are not designed to be stationary. Our ancestors were hunter-gatherers who were forced to live active lives to find food and survive. Unfortunately, today’s lifestyle is increasingly sedentary, which can exacerbate several of the symptoms of healthy aging and aging-related diseases.

aai-logo

If you are reading this article, you might be concerned with the symptoms caused by the declining hormone levels that occur during aging. You might even be receiving or considering HGH & Testosterone Therapy with AAI Rejuvenation Clinic. However, did you know that building and maintaining a regular exercise regime can increase your energy levels, reduce pain and the symptoms of illness, and improve your mood and memory? Exercise is a critical part of healthy aging. Read on to learn more about how exercise can complement your hormone replacement therapy to help you feel young and full of life.

Physical Benefits of Exercise

Although the tangible benefits of exercise are clear, some people still avoid exercising because of their age, physical state, or lack of time. None of these are good excuses! Exercise is crucial for all of us, whether we need to lose weight, want to build muscle, or strengthen our joints. The physical benefits of exercise include:

  • Fat loss and muscle gain. One of the best-characterized effects of a well-designed exercise regimen is an altered body composition, which results in a reduced fat mass and an increased muscle mass. Although this may not manifest as “weight loss,” since muscle weighs more than fat, these changes in your physical composition are highly desirable!
  • Improved mobility, balance, flexibility, and coordination. Movement, balance, and coordination are critical for so many aspects of daily life but, unfortunately, these often decline as we age. Several low-impact exercises can improve your balance and coordination, and some exercise suggested by the Mayo Clinic can be found. Nevertheless, please bear in mind that only physician-supervised exercise programs should be followed to ensure that you receive the maximal benefit without risking your health.
  • Reduce the risk of chronic diseases. The long-term benefits of a healthy lifestyle that includes regular exercise seem to be never-ending. For example, active individuals have a significantly lower risk of diseases such as obesity, diabetes, heart disease, osteoporosis, Alzheimer’s disease, and even cancer [1-3]. Although the mechanisms behind these effects are involved, they include improved immune function, enhanced metabolism, lower blood pressure, improved digestion, and increased hormone secretion.

 

the importance of exercise

Emotional and Mental Benefits of Exercise

The benefits associated with a regular exercise program are not just physical! By helping to normalize your hormone levels, improving your immune and metabolic function, and enhancing your body composition, exercise also has the following mental and emotional benefits:

  • Reduced stress and improved mood. A key advantage of exercise is its ability to rapidly and efficiently reduce weight [4]. Exercise stimulates the release of endorphins, which result in a feeling of happiness and reduced anxiety and sadness [5]. Because being physically active reduces your fat mass and increases your muscle mass, active individuals often have more confidence, which further improves mood.
  • Improved sleep. Science has confirmed that regular exercise helps you fall asleep faster and stay asleep longer [6]. Indeed, people who do not do get regular exercise are more likely to feel tired during the day.

 

non-excercise

Boost Your Hormone Levels

In addition to all the fantastic benefits described above, exercise can also boost the body’s natural hormone production via a number of mechanisms. The ability of exercise to stimulate testosterone therapy, GH, and IGF-I output has been reported in several different populations. For example:

  • The Importance of Exercise free testosterone levels in women [7].
  • The Importance of Exercise such as resistance training reduces blood pressure and increases testosterone levels in overweight and obese men [8, 9].
  • Anaerobic exercise increases IGF-I levels in young men and GH levels in both men and women [10].

Testosterone Injections – Curious about testosterone injections Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698

Isn’t it wonderful to know that taking a little time out of your day can not only make you feel great but also improve the results of your hormone-replacement protocol?

Hopefully, you now know about just some of the benefits associated with a healthy lifestyle that includes regular exercise and understands how this can work hand-in-hand with your hormone-replacement protocol to lead you toward a healthier tomorrow. Talk to your physician to get started today. 

Testosterone Therapy Information

References

  1. Hoffman, A.J., The Impact of Physical Activity for Cancer Prevention: Implications for Nurses. Semin Oncol Nurs, 2016. 32(3): p. 255-72.
  2. Ross, M.D., E. Malone, and G. Florida-James, Vascular Ageing and The Importance of working out: Focus on Cellular Reparative Processes. Oxid Med Cell Longev, 2016. 2016: p. 3583956.
  3. Aune, D., et al., Physical activity and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis. Eur J Epidemiol, 2015. 30(7): p. 529-42.
  4. Sciolino, N.R. and P.V. Holmes, The Importance of working out offer anxiolytic potential: a role for stress and brain noradrenergic-galaninergic mechanisms. Neurosci Biobehav Rev, 2012. 36(9): p. 1965-84.
  5. Thoren, P., et al., Endorphins and The Importance of working out: physiological mechanisms and clinical implications. Med Sci Sports Exerc, 1990. 22(4): p. 417-28.
  6. Chennaoui, M., et al., Sleep and The Importance of working out: a reciprocal issue? Sleep Med Rev, 2015. 20: p. 59-72.
  7. Lane, A.R., C.B. O’Leary, and A.C. Hackney, Menstrual cycle phase effects free testosterone responses to prolonged aerobic. Acta Physiol Hung, 2015. 102(3): p. 336-41.
  8. Kumagai, H., et al., Lifestyle modification increases serum testosterone level and decreases central blood pressure in overweight and obese men. Endocr J, 2015. 62(5): p. 423-30.
  9. O’Leary, C.B. and A.C. Hackney, Acute and chronic effects of resistance working out on the testosterone and cortisol responses in obese males: a systematic review. Physiol Res, 2014. 63(6): p. 693-704.
  10. Eliakim, A., et al., Effect of gender on the GH-IGF-I response to anaerobic working out in young adults. J Strength Cond Res, 2014. 28(12): p. 3411-5.

October 25, 2016 by Joseph Fermin 3 Comments

Turmeric Health Benefits

Turmeric and The Health Benefits

Turmeric, Several plants, and their extracts have been reported to have health benefits, and it can be difficult to know what is true. Are all these things as good as they seem? For turmeric, the answer is a resounding yes!

Turmeric is an herbal plant grown in Asia. The roots are used to make the yellow spice turmeric, which is most commonly used in Indian, Pakistani, Bangladeshi, and Iranian cooking. It is the main spice in curries and is also used to color cheese and butter.

Although the health benefits of turmeric have been known for thousands of years in traditional Chinese and Ayurvedic medicine, it has only recently been appreciated in Western medicine. Curcumin is a phenolic curcuminoid that is thought to be responsible for many of the health benefits of turmeric. It has potent and well-characterized antioxidative and anti-inflammatory effects. Read on to learn more about the other ways in which this amazing spice can boost your health.

turmeric

 

Anticancer effects

Cancer development is a highly complex process that involves DNA damage, inflammation, and the disruption of cellular signaling and death pathways. Although the data are preliminary, there is a certain amount of excitement in the oncology community because curcumin can affect several of these pathways to exert anticancer effects.

Specific clinical trials in patients with cancer are ongoing, but the available results suggest that curcumin could be an effective treatment for multiple cancers, including multiple myeloma, head, and neck squamous cell carcinoma, and pancreatic, prostate, breast, colorectal, lung, and oral cancers [1].

 

Cognitive function

An exciting recent discovery is that turmeric could improve cognitive function in elderly individuals. An Australian study published in April 2016 administered placebo control or a form of curcumin to 96 community-dwelling older adults for 1 year. Various cognitive functions were tested before treatment and at 6- and 12-months. Subjects that received placebo exhibited a cognitive decline at 6 months, whereas those that received curcumin did not [2].

Although the Australian study was not definitive, the available data suggest that curcumin could have several anti-Alzheimer’s disease effects such as preventing the production and aggregation of β-amyloid in the brain and also regenerating brain cells [3]. Taken together, these data suggest that the regular intake of turmeric might reduce the aging-associated decline in cognitive function.

 brain-and-boosts

 

Increase testosterone levels

As anyone reading this blog understands, declining testosterone levels during normal aging are associated with several negative effects on health. Recent research has suggested that turmeric might increase testosterone levels in different ways. First, it can help reverse a number of conditions that can contribute to reduced low testosterone production, such as high cholesterol and dysregulated blood sugar.

The anti-oxidative effects of turmeric can also prevent oxidative damage to Leydig cells in the testis, which could, in turn, normalize with testosterone injections. In mice, turmeric could improve fertility by protecting the testes from various stressors [4, 5].

Who knew that eating curry could improve your testosterone levels and fertility!

 

Metabolic diseases

Curcumin exhibits a seemingly endless number of beneficial metabolic effects. For example:

  • It can increase the levels of HDL or good cholesterol and lower the levels of LDL or bad cholesterol [6]. This is important because low HDL levels and high LDL levels are risk factors for metabolic syndrome and type 2 diabetes.
  • It reduces blood glucose levels and improves glucose metabolism in rodent models, suggesting that it could be an effective treatment for diabetes [7].

 

How to make the most of your turmeric intake

Now you know about just some of the health benefits of turmeric, it is important to understand how to make the most of it. As with all drugs or supplements, the actions of turmeric are limited by its bioavailability, which is defined as the amount that is biologically available to exert its physiological effects. The bioavailability of a drug declines as it is metabolized in the liver, which is a particular concern with any drug or supplement that is administered orally.

One of the best ways to increase the bioavailability of curcumin is to consume turmeric-rich foods with black pepper. Black pepper contains a substance named piperine, which is a potent inhibitor of UDP-glucuronosyltransferase (one of the liver enzymes responsible for drug metabolism) [8]. Indeed, eating even a small amount of piperine with turmeric could increase the bioavailability of turmeric by around 2000% [9].

Curcumin absorption can also be enhanced by consuming turmeric with fats because turmeric is fat-soluble. There are two ways to achieve this: ingest turmeric powder with a healthy fat such as olive oil, or consume natural turmeric root, which contains natural oils that promote its solubility.

Testosterone Injections – Curious about testosterone injections Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698

References

  1. Gupta, S.C., S. Patchva, and B.B. Aggarwal, Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials. The AAPS Journal, 2013. 15(1): p. 195-218.
  2. Rainey-Smith, S.R., et al., Curcumin and cognition: a randomised, placebo-controlled, double-blind study of community-dwelling older adults. British Journal of Nutrition, 2016. 115(12): p. 2106-2113.
  3. Goozee, K.G., et al., Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer’s disease. Br J Nutr, 2016. 115(3): p. 449-65.
  4. Lin, C., et al., Curcumin dose-dependently improves spermatogenic disorders induced by scrotal heat stress in mice. Food Funct, 2015. 6(12): p. 3770-7.
  5. Coskun, G., et al., Ameliorating effects of curcumin on nicotine-induced mice testes. Turk J Med Sci, 2016. 46(2): p. 549-60.
  6. Yang, Y.S., et al., Lipid-lowering effects of curcumin in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled trial. Phytother Res, 2014. 28(12): p. 1770-7.
  7. Nabavi, S.F., et al., Curcumin: a natural product for diabetes and its complications. Curr Top Med Chem, 2015. 15(23): p. 2445-55.
  8. Grill, A.E., B. Koniar, and J. Panyam, Co-delivery of natural metabolic inhibitors in a self-microemulsifying drug delivery system for improved oral bioavailability of curcumin. Drug Deliv Transl Res, 2014. 4(4): p. 344-52.
  9. Shoba, G., et al., Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med, 1998. 64(4): p. 353-6.

August 29, 2016 by admin 0 Comments

Natural Eggshell Membrane (NEM)

Natural Eggshell Membrane (NEM)

Natural eggshell membrane

Natural Eggshell Membrane: The membrane film on the inside of an eggshell is made of the exact ingredients that human joints are made of. It is a true, natural source of hyaluronic acid, glucosamine, and chondroitin. People with osteoarthritis (knee and joint stiffness) have seen amazing results from this new alternative to joint and tendon management. In fact, many have been able to get off pain medications completely once they started using NEM on a continual basis, after only a considerably short period. Customary treatments for osteoarthritis primarily attempt to focus on the symptoms (pain, discomfort, and inflammation) related to the disease. For the most part, this involves the use of anti-inflammatory drugs, analgesics, and COX-2 inhibitors. Most arthritis drugs have negative side effects. There are natural alternatives that are proving to be unexpectedly effective. Most importantly, they come with no negative side effects. Currently, the most prevalent are called “Natural Eggshell Membrane” (NEM).

Case Studies on NEM

  • There was a study in clinical intervention in aging that was done related to the eggshell membrane. It appears, NEM has the Natural eggshell membraneability to reduce symptoms of osteoarthritis significantly and was shown superior to glucosamine and chondroitin. Another clinical trial performed with humans, 37 of them having osteoarthritis, showed that taking 500 mg of NEM daily resulted in a considerable decrease in pain in 7 to 30 days. [1]
  • In a more extensive study, 39 patients received 500 mg of NEM, once daily, for 30 days. After only seven days, patients described an improvement in flexibility of 27.8%. After thirty days, a 43.7% improvement in flexibility was denoted. These percentages are based on Ontario and McMaster University’s osteoarthritis index. After a month, the average reduction in general pain was 72.5%. [2] This is magnificent news for suffering patients.

Find 100% Natural Eggshell Membrane

Screen Shot 2016-08-29 at 10.52.02 AMThere is a special brand that contains only real NEM. The maker is Membrell. The product is called “Joint Health®”, and the reviews on it are spectacular. Again, it contains only 100% natural eggshell membrane. Ginger and Cherries contain high amounts of anti-inflammatory phytochemicals. These can eliminate pain for gout and arthritis sufferers. However, and most impressively, no food actually rebuilds cartilage, except natural eggshell membrane (NEM). Consider that the most popular joint/arthritis supplements are glucosamine and chondroitin, with sales nearing $1 billion annually.

What Makes NEM Unique?

For starters, Glucosamine is extracted from the shell of shrimp, crab, and lobster. Moreover, chondroitin sulfate is derived from animal cartilage. An example would be sharks. Eggshell membrane is made by separating the actual membrane from the eggshell. The eggshell membrane, once isolated, is partially hydrolyzed and dry-blended. Patients with an egg allergy should avoid taking this supplement.

Natural eggshell membraneNatural eggshell membrane

Animal Age Too, You Know?

There have been marvelous studies yielding positive results on retired racing horses. Most impressively, Membrell also produces a medication that is particularly useful for dogs suffering from arthritis. We get asked about arthritis for pets all the time so, it is great to hear they have made dosages especially geared towards dogs. Maybe, we will get into anti-aging for pets some day. That would be awesome!

AAI Rejuvenation Clinic

If you have any questions or comments or are interested in beginning a testosterone therapy or hGH therapy contact us. We even have Sermorelin therapy for our more committed patients. You can fill out our short form or call us directly:

 

Case Studies

[1] Ruff KJ, DeVore DP, Leu MD, Robinson MA “Eggshell membrane: a possible new natural therapeutic for joint and connective tissue disorders. Results from two open-label human clinical studies.” Clin Interv Aging. 2009; 4: 235 -40

[2] Ruff KJ, Winkler A, Jackon RW, DeVore DP, Ritz BW “Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled clinical study.” Clin Rheumatol. 2009 Aug; 28(8):907-14.

August 25, 2016 by admin 3 Comments

Anavar: The Good, The Bad and The Ugly

Pros and Cons of Anavar

Anavar has been around since 1964. It was bought out by Pfizer in 2003. Since then, it has seen a popular reemergence and has been termed the “safest” steroid available. Unfortunately, this is dangerous and brings confusion to the masses whom misleadingly supplement with this compound.

Anavar

We have been receiving many requests for Anavar from patients that have shopped around with other local clinics. Sadly, clinics that, despite the consequential ramifications, opt to sell this controlled substance to their patients. Moreover, they do it under the guise of providing medical treatment, when in fact, this is one of the reasons it was once illegal: there is no real medicinal purpose for Anavar.

  • Anavar is an anabolic steroid.
  • Anavar is not a bio-identical hormone, as is testosterone.
  • Anavar has very little androgenic (testosterone Injections) properties. This is the reason it does not aromatize. Only androgens aromatize.
  • Initially, Anavar was produced to assist patients with lipodystrophy (excessive muscle loss, usually as a result of AIDS).

The Good, The Bad, and The Ugly.
First the Good

  • Because there is no conversion to estrogen with Anavar, blockers nor inhibitors are needed for its use. Estrogen conversion manifest most of the visible side effects men fear from a testosterone therapy program: mood swings, libido loss, water retention, weight gain, etc.
  • Anavar increases anabolism significantly. This allows the muscle to absorb a lot more protein. Being in anabolic state intensifies the muscle building process. Strong, dense muscles develop and are longer lasting than when developed on other steroids.
  • Because Anavar has almost no androgenic properties, it does not cause a swift shutdown of HPTA (the process that invites endogenous low testosterone production)
  • Muscles developed with the aid of Anavar administration are sharper and more cut.
  • Studies have shown Anavar to diminish visceral (stomach area) fat with only moderate exercise. Most impressively, even after discontinuing usage, the subjects kept off the fat. Of course, they were still exercising and minding their caloric intake.
  • Anavar can lubricate joints and assist with joint related pain.

The Bad

  • Want to know the truth behind why Anavar is considered the “safest” or “most mild” anabolic steroid available? In its pharmaceutical form, Anavar comes in 2.5 mg tablets. At that therapeutic dose, even a child could take it without systemic repercussions. There is basically no negative impact on the liver, even if taken on a daily basis.
  • To build significant muscle on Anavar alone, at least 50 mg a day would be needed. At these quantities, arduous taxing of the liver is intense and inevitable.
  • Anavar is a seventeen alpha alkylated. This means it is structured to prevent a breakdown in the liver. This makes the effects of the drug much greater but puts an unimaginably damaging strain on the liver.
  • The required dosage for effective muscle “building” is what makes legitimate medical claims of Anavar’s “mildness” a myth.
  • In a nutshell: With Anavar, what makes it safe, makes it not very effective, and once it becomes effective, it is not very safe.

The Ugly

  • 2.5 mg is the pharmaceutical dosage this brand medication comes in. Patients should be wary of 20 mg to 50 mg tablets. Those are only made through UG laboratories. Patients should require their medication come labeled with their name, the prescribing physician’s name and the providing Laboratories information, including DEA number. This info should be followed up with some quick research on the involved laboratory.
  • Unless you are suffering from acute muscle wasting, there is no medicinal purpose for taking Anavar.
  • Anavar is actually pretty amazing stuff “if you are a bodybuilder willing to administer illegal substances.” It does have the ability to increase strength significantly in a short period of time. However, at the dosages required for effective muscle building, the liver finds itself under constant attack. This program can only be used as a kick-start program.
  • Patients prescribed Anavar under the guise of it being a health supplement should consider very carefully the integrity of the organization they are working with.
  • A “real” Anavar program should not surpass 4 to 6 weeks. Anything beyond that, especially at dosages beyond the 20mg mark, will have impacting effects on the liver.
Real Testosterone Therapy

anavarIn conclusion, Anavar, if abused, is actually the real deal. It then works well to strengthen muscles and build rigid, strong tissue. It might even assist with the loss of stubborn belly fat. Unfortunately, 1) the dosage needed makes it unimaginably toxic to the liver and 2) there is no actual medical use for it and cannot be taken for very long at all. For this reason, unless you are a bodybuilder willing to trade in your future health for accelerated, temporary gains now, Anavar should never be on your radar.

If you are looking for a supplement to take to maximize your masculine efficiency while ensuring a health-enjoying, long, quality life in the future, consider learning more about a bio-identical Testosterone replacement protocol.

Again, if you are considering bettering your health, changing your physique, improving your sex life and libido, consider a bio-identical testosterone replacement program. We can provide you the same type of testosterone your body produces. Of course, there is still the potential for side effects but, because it is bio-identical, your body is more receptive to it and you can continue therapy safely for many years. Most importantly, our doctors are experts in the art of Testosterone replacement therapy. We make sure our patients have all the required counterparts to their therapy to ensure better keeping unwanted side effects out of the picture.

A properly administered testosterone injection program can reignite the fire you have lost. It may sound intense, but the results of revitalizing the male body are unparalleled and near impossible to denote. It is simply a reawakening of life; a happier, more efficient life.

Testosterone Therapy Information

August 24, 2016 by admin 0 Comments

Why AAI Rejuvenation Clinic?

Why AAI Rejuvenation Clinic?

AAI Rejuvenation Clinic is breaking the mold. In a very short period, we have brought our ranking position to be noted as one of the best hormone health centers in existence. A quick Google search for “best hormone clinic in the country” yields first page results containing AAI Clinics as one of the first brick and mortar locations available for selection.

What is Actually Done at AAI Clinics?

AAI Rejuvenation Clinic is a hormone clinic. No, hormones are not only for athletes or the elderly. That is a huge misconception keeping millions of people away from enjoying their happiest and healthiest life possible.

  • We only age because our hormone levels recede.
  • By the age of 27, we all begin the aging process.
  • Replacing your hormones to maintain healthy levels, similar to the levels you had during youth, helps the body operate more efficiently and remain younger, longer.
  • If you are a bit older and return your hormones to healthy levels, tissue throughout the body essentially strengthens and rejuvenates.
  • The body positively responds to the higher, healthier hormone levels.

What’s Different at AAI?

Patients do not only receive hormones – You cannot help heal 1 million different people’s health problems with a group of only 15 basic medications and hormones. Other compounds are necessary and vary from person to person. We supply these.

Therapy-supporting nutraceuticals – Depending on patient goals and individual ailments, targeted supplements are also prescribed to maximize results and the efficiency of therapy. We practice focused healing and goal achieving.

Most competitive pricing in the industry – From inception, we have known this industry is saturated with overpriced margins. We knew providing exceptional patient care in conjunction with the best available pricing was an impermeable recipe for everybody’s success.

Healing from the core – Foods are medicine. We provide information on symptom-focused healing foods, including viable recipes and food “per item” nutritional details and medicinal property explanations. Eating the right foods to heal your body and reach your goals is one of the biggest kept secrets, yet fastest ways to obtain lasting results.

Hassle free – 

1. Patients only need three simple documents for qualification.
2. Patients never need to leave their city.
3. Individualized assistance via assigned medical professional 7 days a week from 9 AM to 10 PM EST.
4. Prescription fills delivered to home or office in discrete packaging.
5. Prescribing Physician’s online or phone consults available.
6. For our busy patients, a physician’s visit to their home or office can be organized.

Promotions at AAI Rejuvenation Clinic

  • Physician’s consult and Initial qualifying blood work are now an all-inclusive, one-time fee. Instead of charging patients individually for blood work as well as the required doctor’s consult, we now offer a one-time transaction that saves patients about 30% overall.
  • Are you interested in testosterone therapy, sermorelin therapy or hGH therapy? Let us give you facts.
  • You can be on your way to feeling younger, better and healthier in less than 4 days.
  • Fill out our short form and be contacted within 24 business hours.

 

Symptoms Therapy Information

August 5, 2016 by admin 0 Comments

Tongkat Ali (Tonic Herb)

What are the Health Benefits of Tongkat Ali Regarding

Testosterone Levels, Sex Drive, and Muscle Growth?

tongkat-ali

Tongkat Ali may sound a little funny to say but, do not let the name fool you. This little herb packs quite the punch when regarding its positive effects on a male’s libido and hormone secretion. After the age of 27, the male body begins to change. There is a shift in the production of testosterone. Testosterone is the main sex hormone found in men. It is the most prominent of all their hormones and its decline manifests in an array of afflictions that chisel away at a happy life. To name a few, and most common:

  • Reduction in the desire for sex.tangkat ali
  • The decline in sexual performance.
  • Lack of energy.
  • An increase in body fat.
  • The decrease in muscle mass.
  • Mental lethargy.

Testosterone replacement therapy is definitely an excellent choice for qualifying men suffering from a diagnosed hypogonadal issue. Men should, however, always try to naturally increase their own body’s production of testosterone before introducing the hormone exogenously.

Foods Are Medicine!

  • Knowing what foods and organic substances contain the medicinal properties we require to help us reach our wellness goals is essential to our future health.

tangkat aliThe world is changing, and the idea of illness regression through food therapy is becoming more widely accepted and better understood. Now clinical studies are being done on specific fruits, vegetables, herbs, plants, roots, and many other organic sources to evaluate and prove their medicinal properties and healing potential.

Tongkat Ali, also known as Eurycoma lungi folia jack or Malaysian Ginseng, is a tonic herb found mainly in the Malaysian rain forests. It has been appropriated for many years in traditional medicine to help promote a healthier libido in men and assist them with the balancing of their hormones. Tongkat Ali was most commonly used as an aphrodisiac.

Tongkat Ali Helps Testosterone Production

Tongkat Ali has specific properties that, in clinical trials, has shown to stimulate libido in the studied animals. It also showed to promote better semen quality and muscle growth. All of these reactions are associated and attributed to healthier, more elevated levels of testosterone. [1] [2] [3] [4]. tangkat ali

In 2012, a study was conducted in Malaysia where seventy-six men were supplied Tongkat Ali for a full month. Out of these men, 35% of them did not have testosterone level issues. After only a month, the same group of men, which now consisted of 90% of them having normal testosterone levels, expressed the palpable betterment that they had been experiencing overall since beginning supplementation. [5]

In addition to that test, a double-blind, placebo-controlled test noted that men that supplemented with Tongkat Ali every day experienced improvements in libido, semen volume, and erectile function. There were even some subjects that suggested fat loss occurred as a result of Tongkat Ali consumption. [6]

Male Fertility and Tongkat Ali

Because of how Tongkat Ali can naturally incite the production of testosterone, which stimulates the testicles, maximizing their efficiency, it also helps with promoting better sperm quality.
Sperm quality is measured by:tangkat ali

• Motility
• Concentration
• Volume

These components can impact male fertility. [7]

Another test conducted with seventy-five men whom every day supplemented with Tongkat Ali denoted the men had significant improvements in sperm quality. Moreover, these developments lasted months after the initial test was piloted. In one study, Tongkat Ali was given to seventy-five men every day for 45 days. These men saw a significant change for the better in regards to sperm quality; improvements that lasted for months after the initial study was conducted. Also, pregnancies were reported by almost 15% of the participants. [8]

Purchase Tongkat Ali

Despite the fact that there is an abundance of studies showing the effectiveness of Tongkat Ali to increase testosterone levels and improve libido, it is not that easy to obtain. The internet has been saturated with supposed sexual enhancement products and research has demonstrated that many of those supplements are not what they claim to be. What’s worse, many of the scam-meds contain harmful chemicals, including mercury. [9] [10]

tangkat aliMake sure that the Tongkat Ali you are considering purchasing is coming from a well known, established pharmaceutical organization. The biochemistry organization that supplements our patients do have a product that contains Tongkat Ali. The product is called TestoGain™. It is quite the remarkable product for men interested in naturally assisting to better their testosterone levels. When it is time for testosterone therapy, there is nothing that compares to injectable therapy to quickly and efficiently elevate testosterone levels. That being said, naturally aiding your body to function on its own should always be the first course of action for any man looking to improve their life by returning to healthy testosterone levels. Below is the label directly off the TestoGain™ bottle so you can research the incredibly beneficial ingredients joined together in this arguably life transforming capsule. If interested, click to purchase TestoGain™.

Tongkat Ali

Do a little research on our supplier, Douglas Labs. They are the only biotechnological, pharmaceutical organization with two ISO certifications. Typically, the legal requirement is one ISO certification, just to give a simple indication of the standards by which this organization operates.

Contact us about anything that has to do with Testosterone therapy, HGH therapy or any other hormone-related therapy you may be interested in. You can fill out our short form and be contacted within 24 business hours, or you can call us directly during normal business hours at:

(866) 224-5698

Case studies:

[1] Ang HH, Lee KL, Kiyoshi M. Eurycoma longifolia Jack enhances sexual motivation in middle-aged male mice. J Basic Clin Physiol Pharmacol. 2003;14(3):301-8.

[2] Ang HH, Sim MK. Eurycoma longifolia Jack enhances libido in sexually experienced male rats. Exp Anim. 1997 Oct;46(4):287-90.

[3] Ang HH, Ngai TH, Tan TH. Effects of Eurycoma longifolia Jack on sexual qualities in middle aged male rats. Phytomedicine. 2003;10(6-7):590-3.

[4] Zanoli P, Zavatti M, Montanari C, Baraldi M. Influence of Eurycoma longifolia on the copulatory activity of sexually sluggish and impotent male rats. J Ethnopharmacol. 2009 Nov 12;126(2):308-13. doi: 10.1016/j.jep.2009.08.021. Epub 2009 Aug 22.

[5] Tambi MI, Imran MK, Henkel RR. Standardized water-soluble extract of Eurycoma longifolia, Tongkat Ali, as the testosterone booster for managing men with late-onset hypogonadism? Andrologia. 2012 May;44 Suppl 1:226-30. doi: 10.1111/j.1439-0272.2011.01168.x. Epub 2011 Jun 15.

[6] Ismail SB, Wan Mohammad WM, George A, Nik Hussain NH, Musthapa Kamal ZM, Liske E. Randomized Clinical Trial on the Use of PHYSTA Freeze-Dried Water Extract of Eurycoma longifolia for the Improvement of Quality of Life and Sexual Well-Being in Men. Evid Based Complement Alternat Med. 2012;2012:429268. doi: 10.1155/2012/429268. Epub 2012 Nov 1.

[7] Chan KL, Low BS, Teh CH, Das PK. The effect of Eurycoma longifolia on sperm quality of male rats. Nat Prod Commun. 2009 Oct;4(10):1331-6.

[8] Tambi MI, Imran MK. Eurycoma longifolia Jack in managing idiopathic male infertility. Asian J Androl. 2010 May;12(3):376-80. doi: 10.1038/aja.2010.7. Epub 2010 Mar 29.

[9] G Jackson, S Arver, I Banks, and V J Stecher. Counterfeit phosphodiesterase type 5 inhibitors pose significant safety risks. Int J Clin Pract. 2010 March; 64(4): 497–504.

[10] Ang HH, Lee KL. Contamination of mercury in tongkat Ali hitam herbal preparations. Food Chem Toxicol. 2006 Aug;44(8):1245-50. Epub 2006 Mar 29.
blog_the_benefits_of_tongkat_ali_for_male_enhancement_3

July 28, 2016 by admin 1 Comment

Clomiphene

Clomiphene, Men, the UFC

Clomiphene is not only used to help with fertility in women. It can serve a very necessary role in men too. Not too long ago, UFC and WWE Star Brock Lesnar was given a drug test by United States Anti-Doping Agency and failed it. This was done for his UFC 200 fight. The discrepancy is in the fact that Lesnar’s results did not come back before he competed. They had not been able to officially identify the exact substance that was in his system. A source did tell ESPN that clomiphene is what Brock Lesnar tested positive for. The purpose of clomiphene is to block estrogen in the body. It happens to be the most sought-after drug of choice for men on testosterone therapy. It is also the same medication that eliminated Jon Jones from competing at UFC 200.

How Does Clomiphene Work? Why Is It The Most Popular Drug for Men on TRT?

Remember, the same way that women produce testosterone, men also produce estrogen. Estrogen is actually important in our clomiphene body. Men think it is only about testosterone but, if you have no estrogen, you cannot build muscle. Conversely, if you have too much estrogen, as a male, an array of unwanted side effects can surface and negatively impact any gains from being on TRT. This is where the use of clomiphene comes in.

Men on TRT are doing so to purposefully increase their testosterone levels due to naturally declining levels. This usually begins to occur at the age of 27. When testosterone levels are increased via external sources, the body passes its own production of testosterone. This also causes shrinkage in the testes from not having to work to produce testosterone. At the same time, elevated levels of testosterone therapy result in elevated levels of estrogen in the blood, as a percentage of testosterone injections, therapy aromatizes, which converts it to estrogen.

For these reasons, men cannot stay on TRT forever. Their programs need to be cycled. When men are done with a cycle, clomiphene is introduced to their protocol to help reverse the endocrine impact of introducing testosterone from an exogenous source. Clomiphene works as an estrogen blocker in men. When men are not introducing more testosterone to the body, the balance between testosterone and estrogen goes off, in favor of estrogen. If no action were taken, it would take a considerable amount of time for the body to begin to produce testosterone on its own. Clomiphene invites and accelerates a man’s natural production of testosterone. The natural reaction of the body from having estrogen blocked is to produce testosterone. This helps reactivate the LH and FSH, the signal from the brain to the testes to produce testosterone and sperm. This also assists with any testicular shrinkage that may have occurred during treatment.

clomiphene

It is important to note that this situation is time sensitive. Because this TRT user is not introducing testosterone to the body, his testosterone levels quickly decline. When this happens, he begins to lose all the gains made while on TRT. The culprit for this unfortunate turn of events is cortisol. Cortisol is a hormone that dominates the body while there is no production and little testosterone. In this stage, you can regard cortisol as simply eating away at the muscle that was gained while on testosterone therapy.

At AAI Rejuvenation Clinic, we ensure that a patient’s program is well encompassed and includes everything necessary to enjoy the benefits of testosterone while best-avoiding everything we have learned in this passage.

Clomiphene is considered a safe medication to use for TRT users. It is considered to have manageable side effects. Side effects include headaches, hot flashes, dizziness, temporarily blurred vision and nausea. What is interesting is these side effects seldom are observed in male users.

Now that it is been determined that Brock Lesnar was using clomiphene, does it confirm he was on testosterone therapy?

This coming SummerSlam is supposed to have Randy Orton and Brock Lesnar facing off, in the WWE. This is PPV second biggest event of the year. It will be interesting to see how this all plays out.

If you have any questions about this article or are interested in knowing how to qualify and participate in testosterone therapy, please fill our short form or call us directly: