Prostate Cancer: Main article details obtained from the U.S. National Library of Medicine
Testosterone Therapy and Prostate Cancer
Prostate Cancer and Testosterone Therapy and Prostate cancer is a considerably well-known paradox. Did you know there is no evidence that testosterone therapy causes prostate cancer? We have presented doctors and interested people at seminars with an alternative view to the misdirection that Harvard’s Chief of Urology made in the 1930s. Mistakes are so egregious that they are still quoted as fact. The most outlandish mistake acknowledged a few years ago by Harvard Medical Review Board was the error in the 1930s research concluding that testosterone caused prostate cancer.
The peer-reviewed article in a leading Urological Journal below explains in great detail that the modern research into this issue shows, once again, no relationship at all between an increase in prostate cancers and even PSIs and testosterone replacement therapy.
This Peer Reviewed scientific Article was written by Dr. Michael K Brawer, M.D., one of the foremost research Urologists in the USA. He has written over 200 articles, 25 books, and 74 government-funded grants to study testosterone’s effect on the prostate. What does this mean for our presentation of this issue at AAI Rejuvenation Clinic?
We think it’s a promising twist that deserves to be presented to interested clients and patients, explaining that:
- Recent advances in urological research show no connection between testosterone and an increased risk of prostate cancer.
- There is only one peer-reviewed study in patients with advanced prostate cancer that testosterone was shown to have any harmful effect on a prostate that already had advanced cancer.
- This is the route taken by Dr. Janine Cabanellas, M.D., a Harvard-trained Dr. who now owns the Wellington Institute of Wellness and Anti-Aging.
We at AAI Clinics want to express our interest in staying on top of the latest and most up-to-date medical advances and research.
We also aim to continually educate our clients and patients with these informational pieces as they surface, even if only in the form of an intellectual discussion such as this one. A meeting of the minds, if you will. Retrospectively, despite the more recent studies pointing to the fact that the connection between testosterone therapy and prostate cancer may be a high-profile medical misconception until the general medical consensus has agreed and changed in their direction of treatment, the physicians here at AAI Center their patient’s therapies with all the precautionary necessities and medications.
- We are one of the only clinics with a designated section for accompanying nutraceuticals significant to the patient’s therapy and focused on minimizing any possible side effects.
- Our nutraceuticals come exclusively from Douglas Labs.
- Do your research.
Everyone says they are the best. Douglas Labs has the documentation and FDA seals of approval to back the claims.
One of the best nutraceuticals to take while on testosterone therapy (or even if you are not on testosterone therapy) to focus on the health of the prostate is TestoQuench for men.
Check it out. Call us up for $10 off per medication during the next ten days: The effect of hormonal regulation of prostatic tissue growth and function, particularly reflected by serum PSA level, is, of course, a well-studied area. Particular attention has been paid to the effect of androgen withdrawal as a treatment of prostatic carcinoma.
- Several investigations have attempted to correlate serum PSA levels with testosterone levels.
- Two studies, those of Behre and associates and Svetec, demonstrated statistically significantly lower levels of PSA in hypogonadal men than normal men.
- Four other investigations revealed a trend toward lower levels of PSA in hypogonadal men, although this trend did not achieve statistical significance in any of the studies.
Several investigators have measured PSA levels before and after testosterone replacement.
- In six reports, PSA was found to increase significantly after testosterone replacement.
- In others, although there was a tendency for PSA to increase, this trend did not reach statistical significance.
- In only one study investigating this phenomenon, that of Snyder et al., did the PSA level remain unchanged?
- Three investigators examined the chance of PSA increasing above the normal threshold (4.0 ng/mL). In none of these studies did this increase occur?
- Several animal models have demonstrated that exogenous androgens stimulate established prostate cancer in a dose-dependent fashion. Testosterone given to advanced metastatic prostate cancer patients results in severe pain at bony metastatic sites.
- There have been three investigations where supplemental testosterone was given to eugonadal men. Indications were obesity with low normal testosterone in healthy volunteers and men in a long-term contraception trial. None of these investigations on eugonadal men showed an increase in PSA.
Again, the lack of agreement in the study results established no relationship between serum testosterone and PSA.
Cancer Risk and Patient Monitoring
Despite the conclusion that it is highly doubtful that the administration of testosterone therapy produces any promotional effect in the absence of an already existing cancer, the patient needs to be monitored. A standard urologic evaluation to rule out malignancy should be undertaken before initiating androgen supplementation. Recommendations include a carefully performed digital rectal examination (DRE) and serum PSA measurements.
An ultrasound-guided prostate biopsy becomes mandatory if the rectal examination is abnormal or the PSA level exceeds 4.0 ng/mL. If the initial PSA levels are within normal limits and the DRE is negative, one should feel comfortable initiating androgen supplementation in properly identified patients.
The patient must be carefully monitored for any changes in these prostate risk findings, and we recommend reassessment at three months. At that time, if the PSA level exceeds 4.0 ng/mL or there is a change in DRE, the prostate biopsy is warranted. We recommend an additional prostate assessment in 3 more months (6 months after initiating therapy) and at least annually after that.
Conclusion
The effectiveness of testosterone therapy in alleviating the signs and symptoms of hypogonadism in the aging male will lead to increased implementation of this therapy.
Multiple attempts have been made to correlate testosterone administration to prostate carcinogenesis, but the studies have failed to produce consistent results. Similarly, the studies which attempt to connect increased testosterone with increased PSA levels have been unconvincing. Nor have the studies been able to link DHT, the more active metabolite of testosterone, to the development of carcinoma.
The prevailing opinion is that restoring your low testosterone levels to physiologic levels offers no increased risk of carcinoma. However, there is little doubt that the studies show a deleterious effect on existing clinical carcinoma of the prostate.
By eliminating the presence of an existing prostate carcinoma, through physical examination and laboratory studies, before testosterone therapy and continuous patient monitoring throughout treatment, testosterone injection therapy will prove safe concerning prostate health.
~ The great majority of this content came from the U.S. National Library of Medicine ~
Testosterone Therapy Information
- What Is Testosterone?
- Testosterone Therapy Info
- Testosterone Injections
- symptoms of Low Testosterone
- causes of Low Testosterone
- Low Testosterone in Men
- Low Testosterone in Women
- Low Testosterone
- Testosterone Cypionate
- Testosterone Propionate
- Testosterone Enanthate
- Testosterone Patches
- Testosterone Gels
- Testosterone Boosters
- Side Effects of Testosterone
**NOTE** The content in this blog is subject to interpretation and is the opinion of the content writer. We do not claim it to be fact. We encourage you to consult a medical doctor before taking any prescribed medications or supplements.
Conclusion
Supporting Hormones health is essential for overall well-being and vitality. By incorporating regular exercise, proper nutrition, adequate sleep, stress management techniques, and IV therapy, you can help maintain optimal testosterone levels and lead a healthy, balanced life. Always consult a healthcare professional before making significant changes to your lifestyle or starting any new treatments to ensure they suit your needs.
At AAI Rejuvenation Clinic, we advise anyone to think seriously about beginning Hormone treatment if there is no medical need for it. However, we will take every precaution to ensure that you read your program’s positive benefits by providing the latest at-home hormonal mouth-swab testing to ensure we are continually monitoring your progress and aware of any adverse side effects. Fill out the Medical History Form, or if you need more information, call us at (866) 224-5698 or (866) AAI-Low-T.
Low Hormone Symptoms
- Motivation
- Sex Drive and Desire
- Depression
- Fatigue
- Erectile Dysfunction
- Cholesterol
- Low Energy
- Memory Loss
- Osteoporosis
- Wounds & Illness
- Muscle Mass
- Sleep Disturbances
- Thyroid Dysfunction
- Weight Gain
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