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Testosterone Enanthate Information

Testosterone Enanthate

Testosterone enanthate is a slow-acting, long chain ester. It is formulated as an oil-based injectable testosterone compound, and is commonly prescribed for the treatment of hypogonadism-related symptoms. It is very similar to testosterone therapy cypionate.

Testosterone enanthate first appeared in the U.S. prescription drug market during the early 1950s, as Delatestryl by Squibb. It was sold and purchased several times over the years, most notably to Mead Johnson, BTG, Savient and, in December 2005, Indevus. Testosterone enanthate is most prominently featured in a hybrid blend with testosterone propionate under the brand name Testoviron, which has been produced by Schering AG in Germany for more than 50 years.

Testosterone enanthate is testosterone injections that has been esterified with enanthic acid; it has a half-life of ~8–9 days, which is the longest half-life of all common ester-based testosterone analogs. An uncommon testosterone such as Nebido (testosterone undecanoate) has a very long half-life of 3-months. Because it has longer carbon chain and hence a longer half-life, it only has to be administered every 8 or 9 days to maintain efficacious concentrations. Even though AAI Rejuvenation Clinic does not use the standard intramuscular needle tips that most clinics use, as ours are significantly more comfortable to utilize, most patients would still rather administer their testosterone as infrequently as possible.

Testosterone Enanthate Injection, USP provides Testosterone Enanthate Description, USP, a derivative of the primary endogenous androgen testosterone, for intramuscular administration. In their active form, androgens have a 17-beta-hydroxy group. Esterification of the 17-beta-hydroxy group increases the duration of action of testosterone; hydrolysis to free testosterone occurs in vivo. Each mL of sterile, colorless to pale yellow, solution provides 200 mg Testosterone Enanthate, USP in sesame oil with 5 mg chlorobutanol (chloral derivative) as a preservative.

Testosterone Enanthate, USP is designated chemically as androst-4-en-3-one, 17-[(1-oxoheptyl)-oxy]-, (17β)-. 

Structural formula:
Testosterone Enanthate – Clinical Pharmacology

Endogenous androgens are responsible for the normal growth and development of the male sex organs and for maintenance of secondary sex characteristics. These effects include growth and maturation of prostate, seminal vesicles, penis, and scrotum; development of male hair distribution, such as beard, pubic, chest, and axillary hair; laryngeal enlargement; vocal chord thickening; alterations in body musculature; and fat distribution.

Androgens also cause retention of nitrogen, sodium, potassium, and phosphorus, and decreased urinary excretion of calcium. Androgens have been reported to increase protein anabolism and decrease protein catabolism. Nitrogen balance is improved only when there is sufficient intake of calories and protein.

**NOTE** The content in this page is subject to interpretation and is the opinion of the content writer. We do not claim it to be fact. We encourage you to consult a medical doctor before taking any prescribed medications or supplements.


Supporting Hormones health is essential for overall well-being and vitality. By incorporating regular exercise, proper nutrition, adequate sleep, stress management techniques, and IV therapy, you can help maintain optimal testosterone levels and lead a healthy, balanced life. Always consult a healthcare professional before making significant changes to your lifestyle or starting any new treatments to ensure they suit your needs.

At AAI Rejuvenation Clinic, we advise anyone to think seriously about beginning Hormone treatment if there is no medical need for it. However, we will take every precaution to ensure that you read your program’s positive benefits by providing the latest at-home hormonal mouth-swab testing to ensure we are continually monitoring your progress and aware of any adverse side effects. Fill out the Medical History Form, or if you need more information, call us at (866) 224-5698 or (866) AAI-Low-T. 

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