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What Is Testosterone?


Legally, patients are not required to undergo blood work testing more than once every 12 months. However, your treatment protocol at AAI Rejuvenation Clinic is designed and implemented by an actual physician who regularly reviews your program based on the details in your medical file; therefore, you will be encouraged to undergo more frequent blood testing. Although this it is not a requirement, most patients who are interested using their treatment to better their health and future will follow the doctor’s advice regarding repeat blood work to ensure that they get as much out of their protocol as possible. The frequency of the recommended testing will depend on the individual’s response to therapy; some patients need more monitoring than others. If your physician asks you for more blood work, please bear in mind that it is for your overall well-being.

Some of our patients are more experienced, and have been on testosterone therapy for a long time. These individuals know their bodies and understand their reactions to treatment more than someone who is just starting therapy. This is one of the factors that makes AAI Clinics so special. We want to help our patients by allowing them to be a part of their protocol development. Your physician will work with you to ensure that you are getting the most efficient program based on your fitness and health goals and your individual characteristics.

Our focus is to make certain that our patients feel like they have some control in their treatment, while ensuring that the therapy is optimized and side effects are minimal. This is how AAI Rejuvenation Clinic approaches testosterone replacement therapy.

The Best Testosterone Enhancement Regimen Available

At AAI Rejuvenation Clinic, our specialized hormone replacement physicians structure individualized testosterone replacement protocols that are designed to work with each individual’s specific physiology under the instruction and direction of Dr. Gordon Crozier. No two bodies are the same, and so the same protocol will not work the same in each patient. If you do not obtain your testosterone therapy through AAI, there are many reasons why your selected testosterone enhancement regimen might not be providing the results that you expected and hoped for.

Supplemental Pharmaceuticals During Testosterone Therapy

Unfortunately, most men experiencing issues related to low testosterone levels are being treated by their general care practitioners or an endocrinologist. These individuals often find that their non-personalized, cookie-cutter protocol no longer works. This is usually because the treatment regimen does not consist of the necessary supplements that are required to ensure that the most benefits are obtained from the testosterone therapy and, more importantly, to keep unwanted side effects at bay. With AAI Rejuvenation Clinic, you will also be prescribed supporting medications and nutraceuticals to help you get the most out of your treatment.

You probably have several questions. Why isn’t testosterone therapy enough on its own? What happened with my previous treatment? Why did I stop feeling great after 6 months? Can anything be done to stop or regress the side effects of testosterone?

There are a number of different forms of testosterone that you could be receiving, including:

• Testosterone pellets (inserted into the subcutaneous region of your skin)
• Testosterone creams (usually applied daily and rubbed into specifically designated areas of the body to maximize its absorption rate)
• Testosterone patches (similar to a smoker’s patch; it is placed on a shoulder or inner thigh. Skin irritation may occur at the application area)
• Injectable testosterone therapy (usually injected intramuscularly once per week)

Understand that when you control the flux in your testosterone levels, it interferes with your body’s need to produce any of its own testosterone. The brain responds to signals to regulate your hormonal secretion throughout the day; when it detects high testosterone levels, endogenous testosterone production ceases. This physiological change in hormone production alters the functionality of important endocrine glands, including the testes. The extended periods without hormone production and production caused by artificially maintaining and regulating your own testosterone levels will eventually cause hormone-releasing glands to atrophy. The prolonged misuse of these organs can cause permanent damage, irreversible side effects, and unwanted health conditions. Therefore, having a testosterone expert on hand is of paramount importance for patients wanting to maximize their results.

A personalized and individualized testosterone enhancement protocol at AAI Rejuvenation Clinic comes with an array of supporting nutraceuticals. These nutraceuticals support of your testosterone-enhancing therapy and help keep unwanted fluxes in estrogen and other hormones at bay. They also help ensure that your body is absorbing and utilizing nutrients to help focus on increasing your free testosterone levels. This promotes the protein synthesis hoped for and expected from this life-transforming therapy, while regulating preventing the quality of life-deteriorating side effects.

Please contact us at your earliest convenience so we can begin to organize and structure a file for you. Fill out our Medical History form and one of our Wellness Advisors will contact you and go over quotes and specifications to ensure that you have all the information necessary to make the most important and life-optimizing decision of your life.

Endogenous Testosterone Production vs. Exogenous Testosterone Administration

Here, we review the facts associated with testosterone administration and how they relate to your own testosterone production:

After you administer your testosterone injection as directed by your physician on day 1, the following occurs:

• Your testosterone levels begin to rise almost immediately, and they reach a peak after around 2.5 days.
• They then slowly begin to decline until all of the testosterone has been removed your body in 3–14 days.

The length of the period of decline depends on the testosterone ester that the patient is prescribed, which is based on their blood work and health and fitness goals. A testosterone ester is testosterone with chemical ester groups attached at specific places on the molecule; the type of ester attached affects a number of parameters such as the stability and solubility of the testosterone. For example:

• Testosterone cypionate has a half-life* of 7 days
• Testosterone enanthate has a half-life of 8–9 days
• Testosterone propionate has a half-life of 1.5 days

* The half-life of a medication is the time taken for half of the drug to be eliminated from the body.

The Regulation of Endogenous Testosterone Production

The human body constantly senses hormone levels to regulate endogenous hormone production to ensure that all biological functions can be fulfilled. Low levels of circulating testosterone stimulate the production of gonadotropin-releasing hormone (GnRH) in the hypothalamus in the brain. GnRH then activates the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland, which stimulate testosterone synthesis in the testes. However, when testosterone levels are elevated, as occurs in patients receiving testosterone enhancing therapy, GnRH production ceases and so the testes are not stimulated to produce endogenous testosterone.

**NOTE** The content in this page is subject to interpretation and is the opinion of the content writer. We do not claim it to be fact. We encourage you to consult a medical doctor before taking any prescribed medications or supplements.


Supporting Hormones health is essential for overall well-being and vitality. By incorporating regular exercise, proper nutrition, adequate sleep, stress management techniques, and IV therapy, you can help maintain optimal testosterone levels and lead a healthy, balanced life. Always consult a healthcare professional before making significant changes to your lifestyle or starting any new treatments to ensure they suit your needs.

At AAI Rejuvenation Clinic, we advise anyone to think seriously about beginning Hormone treatment if there is no medical need for it. However, we will take every precaution to ensure that you read your program’s positive benefits by providing the latest at-home hormonal mouth-swab testing to ensure we are continually monitoring your progress and aware of any adverse side effects. Fill out the Medical History Form, or if you need more information, call us at (866) 224-5698 or (866) AAI-Low-T. 

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