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HORMONAL OPTIMIZATION, THE ULTIMATE GUIDE

hormone replacement therapy

Taking control of your hormones gives you better control in life. With a vast knowledge of our hormones, we control growth, and almost every part of our development and body functionality is possible.

WHAT ARE HORMONES?

Hormones are tiny chemical substances that travel from the endocrine glands to the intended location through the bloodstream. Because there are many different types of hormones and their functions vary from type to type, their destinations will differ based on the position it is meant to perform. 

Hormones greatly influence the growth, development, and activity of an organism. It is important to note that hormones are produced in response to various stimuli (internal or external. They circulate through the bloodstream, and based on the answer, they will influence specific organs called target organs. They can either speed up (excites), slow down (inhibits), or alter the activities of their target organs.

This is why hormones play such an enormous role in aging. As mentioned above, certain hormones will speed up or slow growth functions and development. This is why kids’ and teenagers’ hormones are always said to be out of whack. They are speeding up and slowing down as kids age quickly in the beginning, and then as they get older, it tapers off. 

Our target organs have cells with unique receptor molecules on their surfaces. The appropriate hormones then fit into these receptor molecules to engage in their function. These functions are achieved by either affecting the permeability of the cell to certain substances, promoting protein synthesis, or increasing the activity of certain enzymes for that organ.

This is where certain hormones can be affected by things such as human growth hormone treatment and anti-aging techniques. When these processes are disrupted or changed, we can slow down hormones that cause us to age faster. 

Hormones also assist the nervous system in coordinating the various parts of the body to develop harmoniously. Therefore, many hormones work on maintaining a consistent internal environment. Some hormones directly impact growth and development, while others may be focused on agility. Some hormones also may affect several organs simultaneously, while others only target specific areas. 

Typically, the body responds to hormones slowly. Slow responses include growth in general, sexual maturity, and pregnancy. Each of these could take months to years rather than a few hours. The exception is that a few hormones produce a rapid response, i.e., adrenaline. 

Testosterone levels are a great example of hormones that may come about quickly but then drop off at a gradual rate in men after the age of 30 or 40. Testosterone is a younger boy will have a quick adrenaline response to sexual maturity, but as they age, that response will slow and become less prevalent. Of course, unless you engage in testosterone therapy. 

Because hormones have a powerful effect on the body’s systems, their production must be balanced, as an imbalance can produce severe outcomes. Serious illnesses can arise if an endocrine organ malfunctions and has too much or too little of its hormones.

PRODUCTION OF HORMONES

Humans have several glands that produce secretions. Some of these deliver their secretion to wherever they are needed through ducts. Exocrine glands are known; however, hormones are created and secreted from glands that do not have chimneys, called endocrine glands or ductless glands. As the name implies, a ductless gland does not have a vent or tube to carry its secretions into the body system.

While the exocrine gland pours its secretions out of the body, endocrine glands are glands of internal secretion Hormones produced by these glands pass directly into the bloodstream. The blood plasma then distributes these hormones to the target organ. 

The body requires only a small number of hormones to bring about their effects on an organ or system, and some feedback mechanism usually regulates these amounts in the blood. If it is overproduced, a signal is sent to the production center to stop production. A password is sent to begin production and secretion if it is lacking. Once the effects of the hormones are over, they are destroyed in the liver and excreted through urine, some within minutes and others lasting for days.

This relates to hormone therapy because these hormones can be blocked/altered from reaching the cell receptors mentioned before. If the function is not completed or able to work, then this can have anti-aging effects as the process is slowed down. 

ENDOCRINE SYSTEM

The Endocrine system comprises all the endocrine glands in the human body. The human body consists of different endocrine glands positioned at specific body areas. These glands could be discrete, like the thyroid and adrenals, or a group(s) of cells within an organ, such as those in the pancreas that produce insulin. 

Before considering the different types of glands, their function, effects of over-secretion, and deficiency, it is essential to consider a small body at the base of the forebrain. It sits just above the pituitary gland called the hypothalamus, and it regulates activities such as temperature control, sleep, and thirst. It also collects information from the brain and sense organs while monitoring the level of hormones in the blood. It acts as a link between the nervous system and the endocrine system.

ENDOCRINE GLANDS

There are seven endocrine glands in the human body. Each has a list of hormonal secretions.

These glands are:

  1. Pituitary Gland
  2. Thyroid Gland
  3. Adrenal Medulla
  4. Adrenal Cortex
  5. Pancreas
  6. Ovaries
  7. Testes

But the glands we mainly focus on when it comes to hormonal therapy are the pituitary, thyroid, ovaries, adrenal medulla, and testes. This is because the easiest hormones to control with anti-aging are melatonin, DHEA, testosterone, estrogen, endorphins, and so on. 

PITUITARY GLAND

The pituitary gland is also called the master gland because its hormones control the activities of the other glands. It is located at the base of the brain, just below the hypothalamus, and consists of two lobes – the anterior and posterior lobes. The anterior lobe secretes growth hormones, gonadotropins, thyroid-stimulating hormones, adrenocorticotropic hormones, and prolactin. The posterior lobe, however, releases oxytocin and antidiuretic hormone.

While the pituitary gland controls many different hormones, we can focus on the growth hormone and its effects on aging. 

GROWTH HORMONE (GH)

Growth hormones are produced mainly during childhood or adolescence; they are made from the pituitary gland and stimulated by the hypothalamus’s growth hormone-releasing factor. The age of an individual influences its release, sometimes stress and exercise.

Growth hormones are targeted at most tissues in the body to promote growth, increase cell production and muscle mass. It also helps regulate protein metabolisms, carbohydrates, and fats. This is done by enhancing protein synthesis, breaking down stored fats, and decreasing glucose uptake by cells while increasing the glucose level in the blood.

The growth hormone is one of the main hormones that can be impacted by hormone therapy to create an absence in the growth hormone itself. By blocking this hormone from its receptors, you can slow down age development for physical appearance. 

Because the idea is to mimic the hormone the pituitary gland produces, the injections are identical in the labs. They then set out to be administered injection therapy by a medical professional. These injections go into the fatty tissues of the body. You will likely go through a series of injections ever so often. 

THYROID-STIMULATING HORMONE

The essential duty of the thyroid-stimulating hormone, as the name implies, is to regulate the secretion of thyroid hormones from the thyroid gland. Therefore, like the thyroid gland, it plays a role in growth, metabolism, and skin function. 

While the specific hormones are the ones that would be altered under the thyroid gland, it is still essential to address TSH as means of anti-aging because it is the starting point for thyroid functions. 

ADRENOCORTICOTROPIC HORMONE (ACTH)

Adrenocorticotropic secretion is caused by stress stimuli such as pain, shock, infection, or extreme cold. It stimulates the growth of adrenal glands and the release of hormones such as cortisol from the adrenal cortex.

Stress plays a significant factor in our aging as more stress ages our bodies faster. That’s why regulating our cortisol levels can considerably affect hormone therapy treatment. 

For instance, this may be treated if you lack or have excessive levels of ACTH. 

Deficiency: The lack of ACTH would decrease the secretion of hormones from the adrenal glands. In severe cases, the person would h the inability of an individual to cope with stress, leading to the death of such a person.

Excess/Over secretion: On the other hand, it leads to the excessive release of hormones from the adrenal glands.

THYROID GLAND

The thyroid gland is butterfly-shaped at the neck region, just below the larynx. It produces and stores the triiodothyronine (T3) and thyroxine (T4) hormones; these hormones are similar in chemical structures and perform the same function in the body.

The thyroid gland, in particular, has been linked to aging. This is because increased aging has been directly correlated with lower TSH levels, as briefly mentioned.   

TRIIODOTHYRONINE (T3) AND THYROXINE (T4)

The secretion of the Thyroid-stimulating hormone from the pituitary gland stimulates the release of T3 and T4. These hormones accelerate the rate of metabolism by causing the breakdown of glucose and fats to release energy and increase cellular respiration and the production of heat; they also enhance an individual’s physical growth and mental development.

Deficiency: The lack of these hormones is known as hypothyroidism. In infants, it leads to cretinism which results in mental, physical, and sexual retardation. In adults, however, it decreases the rate of metabolism, goiter, a significant drop in body temperature, and weight gain since less food is respired.

Excess/Over secretion: Known as hyperthyroidism, this leads to an increase in metabolic rate, which would increase heart rate, oxygen consumption, and body temperature. It could also lead to over-anxiety and weight loss and, in some cases, the growth of tissues behind the eye, known as exophthalmos resulting in the protrusion of the eyeballs from the eye orbits.

ADRENAL MEDULLA

The adrenal medulla occupies the center of the adrenal gland and produces the hormone adrenaline (epinephrine), secreted in times of fright, anger, stress, and anxiety. Adrenaline has several functions, including;

  1. The increase of body blood sugar by speeding up the breakdown of glycogen into glucose in the liver and muscles.
  2. It helps to increase the metabolic rate, and thereby more energy Is released into the tissues for respiration.
  3. It helps in the increase of muscle strength and acts as fatigue resistance.
  4. It helps increase heart rate and raise blood pressure to ensure a faster passage of oxygen and glucose to the muscles.
  5. It aids in the constriction of arteries in the skin, causing pallor, thereby channeling more blood to the forces.
  6. It increases blood coagulation, relaxes the bronchiole, and increases airflow in the lungs.
  7. It causes the dilation of the pupils to enhance vision.
  8. It contracts the hair muscles, causing “goose pimples.”

Deficiency: The lack of adrenaline causes a decrease in blood glucose levels and blood pressure.

Excess/Over secretion: causes the elevation of the blood sugar level, heart rate, and blood pressure.

Note: People with stressful lifestyles are constantly secreting adrenaline into the bloodstream. This regularly prepares their body for action, fight, or flight. But since the action is never taken, continued exposure to that lifestyle and an extended secretion of adrenaline may harm the body. This could result in muscle tension and headaches (migraine)—or even high blood pressure, which can lead to hypertension. Hypertension can turn into strokes and heart diseases, as well as fatigue, pain in the stomach, and even diarrhea.

All these are serious causes that lead to aging more quickly than someone with a more relaxed lifestyle. 

ADRENAL CORTEX

While the adrenal cortex plays a considerable role in hormones for the body, it doesn’t play a massive role in hormones that affect aging. The adrenal cortex is more known for blood pressure regulation. While the adrenal cortex regulates your metabolism and immune system, they don’t have the main hormones that are worked within hormone therapy. 

PANCREAS

The pancreas is another vital organ in our lives, but not one that has to do with hormones and anti-aging qualities. Its function relies heavily on how we respond to high and low blood sugar and insulin production. 

OVARIES

The Ovaries are located in the pelvis and produce estrogen and progesterone. This is where what is commonly referred to as the youth hormones can be worked to slow down the process of aging. 

ESTROGEN

Estrogen production is stimulated in the pituitary gland and during ovary development. It controls the formation and development of the female sex organs and secondary sex characteristics, e.g., breast development and hair growth. It also prevents the menstrual cycle and the development of mammary glands and promotes sexual urges. Estrogen naturally falls as women get older.

Deficiency: A lack of the secretion of estrogen would lead to the underdevelopment of the reproductive system and secondary sex characteristics.

Excess/Over secretion: This would lead to a strange urge for sex.

PROGESTERONE

Also known as the pregnancy hormone, progesterone is produced during ovulation and helps maintain the lining of the uterus after ovulation. It also helps implant a fertilized egg in the uterus wall and the development of breasts during the later month of pregnancy.

Deficiency: A lack of progesterone secretion may lead to the abortion of the fertilized egg from the uterus since it is not implanted in the walls of the uterus.

Excess/Over secretion: would lead to an irregular menstrual cycle, underdevelopment of the mammary gland, and abortion of fertilized egg.

TESTES

The testes are located at the scrotum and produce the hormones Testosterone and androsterone. These hormones are responsible for the development of male physical characteristics.

TESTOSTERONE

Testosterone is a tropic hormone stimulated by the pituitary gland during the development of the testes. It controls the development of the primary and secondary sex characteristics in adults, such as muscular body, deep and loud voice, and hair growth. It also increases sexual urges and promotes blood circulation and cell respiration.

Testosterone naturally decreases as men get older. Different therapies can help combat this.

They mostly come in the forms of:

  • Pills,
  • Gels
  • Patches
  • Injections
  • Creams

Deficiency: Lack of testosterone will result in poor reproductive system development and underdeveloped secondary sex characteristics.

Excess/Over secretion: would lead to an early onset of secondary sexual characteristics in adolescent males and a high sexual urge.

HORMONAL OPTIMIZATION THERAPY

They have discovered the different types of glands and the hormones they secrete. I am confident you found something common: they have an optimal level by which they function. If they fall short or go above this level, it can lead to severe consequences, sometimes death. Besides anti-aging, these reasons are also why hormonal therapy can be relevant.

Hormonal optimization is done after an assessment is carried out to determine the levels of hormones in the body; if it is below its threshold, plans are developed to improve hormonal functions. And if your body is not secreting hormones as it should, HRT could be your option.

Common signs that you may need hormonal therapy are:

  • Mood changes such as irritability. 
  • Physical changes such as unexplained weight loss or weight gain.
  • Low libido
  • Changes in bowel/bladder habits
  • Increased risk of bone loss due to aging, fatigue, and failures of alternative treatments. 

This therapy could quickly restore quality of life with increased energy and less fatigue. Symptoms would also significantly be reduced.

HORMONAL REPLACEMENT AND ANTI-AGING

Aging is a natural phenomenon that happens to every individual over an extended period—the rate at which individual ages can be directly traced to reduced hormonal secretion. The levels of hormones decrease with age. However, some hormones will remain the same from the youth while others increase. But even when the levels of hormones do not decrease, endocrine functions generally reduce with age because hormone receptors become less sensitive.

But with advanced knowledge and technology, aging can be significantly slowed down by carefully manipulating the secretion of these hormones. Specific hormones could be optimized or replaced to increase life expectancy and physical changes resulting from aging.

Aging is not only a factor of how old that individual is but also a function of many factors such as lifestyle and stress. An individual consistently under pressure, for example, will age twice the speed as an individual that exercises moderately and eats healthily. The hormones we’ve listed above directly or indirectly control all these functions. 

Hormone optimization or replacement could also be a great way to combat age-related conditions such as:

  • low testosterone in men, 
  • perimenopause, menopause, or post-menopause syndrome for women
  • Treat deficiencies 

Deficiencies can only be treated after a test is done. The fundamental three reasons for hormone replacement and optimization are disease prevention, physical appearance, and feeling better.

Predominantly hormone growth therapy and testosterone therapy are the most commonly used therapies. There are more options available than just those two. 

COMMON HORMONAL THERAPY

Glands produce essential hormones that are related to aging processes, this includes estrogen, melatonin, endorphins, and testosterone. Below are some hormonal therapies that would help the fight to reduce aging while maintaining a younger-looking appearance. 

MELATONIN THERAPY

Melatonin plays an enormous responsibility in sleep cycle control. It also determines the adequate amount of sleep essential for emotional, mental, and physical well-being. Sleep-deprived people are generally more susceptible to illness or develop a decreased ability to fight off common colds and viruses than persons with an adequate amount of melatonin. Melatonin is widely called the “wonder drug” and is said to extend life expectancy by up to 25%.

It is also known to locate and destroy free radicals that increase the risks of cancer and heart disease. But by the time one ages 40, there is a lower melatonin production. However, melatonin therapy and supplements in minute doses trick the body into believing that we are much younger than we are. Although, it should be taken under caution and a strict recommendation. It should not be taken under certain conditions and age ranges.

ENDORPHINS THERAPY

Endorphins are hormones the brain releases when we exercise. When we exercise, its production and distribution are increased. It enhances an individual’s mood, making one feel good and happy. Research proves that high endorphins keep individuals active while maintaining a positive attitude. This helps reduce stress and the damage stress would often cause our bodies. During HRT, these chemicals can be induced by assisting an individual in reducing stress, thereby slowing aging.

ESTROGEN THERAPY

Estrogen is considered one of the most potent hormones in the body. Aside from helping to prevent breast cancer, heart disease, and bone loss, its level also affects various tissues and organ systems—these range from bones to the liver, brain, and excreta. During childbearing, it also helps women maintain the strength and flexibility of the skin, reproductive organs, blood vessels, and tissues.

This is why estrogen therapy, supplements, and cream would improve wrinkles. The dermatologic literature is full of studies demonstrating the benefits of estrogen on skin thickness, fun, hydration, and hydration. As a woman goes through menopause, she notices changes in her skin that were previously not there. Therefore, adequate estrogen levels for maintaining youthful skin are essential.

TESTOSTERONE THERAPY

Testosterone helps promote the ability of the body to use up the protein in the formation of bone, muscles, and skin. Men aged 40 to 70 often experience a decrease in the levels of testosterone secreted by the body. But like women, they also have the option to use hormone replacement therapies after appropriate consultations and when determined suitable by physicians.

A client will usually undergo testosterone therapy for life once he starts using any of the before-mentioned medications. Some of the most common gels taken are Androgel and Testim.

Androderm is one of the most common patches. While some men prefer injection, the most common one is Depo-Testosterone. 

DHEA THERAPY

The adrenal glands produce DHEA, also fondly called the “fountain of youth” hormone. It is directly connected to our immune capacity, memory, and energy levels, as it plays a vital role in our bone strength and density. It also plays a role in how each person can handle stress. DHEA is also available as a supplement, as are estrogen, testosterone, melatonin, and estrogen replacement therapy.

ACTH THERAPY

ACTH is also known as the body’s stress hormone. Frequently, chronic stress has a negative influence on our aging process. ACTH stimulates the adrenal gland to secrete and disperse cortisol through the body. Although cortisol is necessary for many-body operations, when it is released as a response to stress, it may lead to adverse effects such as poor skin condition, weight change, premature aging of immune cells, aches, fatigue, pains, and insomnia.

PROGESTERONE

Progesterone can help improve skin conditions, aid sleep and anxiety, and is equally important to women’s health. It is synergistic with estrogen.

OTHER HORMONES

Some other hormones, including melatonin, help with sleep. Vitamin D is also a hormone and can improve immunity and skin enhancement. Pregnenolone helps with cognition—metformin for weight reduction, and so forth.

Consumers, however, should bear in mind that any hormone supplements should be taken with great caution, as too much may create even more significant hormone imbalances within the body. Discussing hormone supplementation with a doctor is essential for those in their mid-40s or older. It is imperative to consult a proven clinician with a lot of expertise, as taking certain hormones without consultation and dosage without prescription could cause more harm than good.

Why Is AAI Clinic Your Best Bet Right Now?

  1. AAI Is Affiliated With FDA And HIPAA-Compliant Pharmacies: AAI Clinics places a high value on quality and sets the same standard for their patients’ pharmaceutical products. They purchase and receive supplies only from the best, government-approved pharmaceuticals in the world. In turn, these pharmaceutical Companies deliver their goods quickly. As a patient of AAI, the chances that you are getting the best healthcare worldwide are around 80 percent. 
  2. Continuous Support from Wellness Advisors: In most healthcare services, support and communication cease when payment is due, or you’ve gotten your share of the treatment. That is not to be said of AAI Clinic. You can always ask questions as it concerns your health and gets the feedback you tightly deserve.

Should an issue arise regarding the product you are using or you have a 

complaint, a customer service team is readily available to cater to your needs.

As a patient with AAI Clinic, treatment no less than family is guaranteed:

  1. Availability of Individual Protocols: AAI Clinic does not offer its service to its patients in groups or packs because each patient’s needs differ. The service is listed on a one-on-one basis. Therefore, adequate attention is given to patients. In some cases, more often than not, this method helps to administer the proper treatment to those who need it.
  2.  Effective Follow-Up: AAI Clinic experts keep up with your health progress. They give you extra-patient care. Not only will you be able to get feedback from them, but they will also be getting from you on how the therapy is going, the supplements you are using, or possibly the anti-aging serum that may have been prescribed to you.
  3. Powerful Reviews From Around The Nation: AAI Rejuvenation Clinic has gained fame for its fantastic result nationwide and is fast rising to become the Number 1 Rejuvenation Clinic worldwide. With its excellent quality services and offers, past patients have left positive reviews leaving AAI highly ranked on Google. 

Start With AAI Rejuvenation 

AAI Rejuvenation is a nationwide HRT clinic that can help you get started with a specific therapy customized for you. We have an in-depth due diligence process that helps us determine what your health looks like. With this, we can determine what therapies may be appropriate options to improve your quality of life. Contact us today!

**NOTE** The content in this blog is subject to interpretation and is the opinion of the content writer. We do not claim it to be fact. We encourage you to consult a medical doctor before taking any prescribed medications or supplements.

Conclusion

Supporting Hormones health is essential for overall well-being and vitality. By incorporating regular exercise, proper nutrition, adequate sleep, stress management techniques, and IV therapy, you can help maintain optimal testosterone levels and lead a healthy, balanced life. Always consult a healthcare professional before making significant changes to your lifestyle or starting any new treatments to ensure they suit your needs.

At AAI Rejuvenation Clinic, we advise anyone to think seriously about beginning Hormone treatment if there is no medical need for it. However, we will take every precaution to ensure that you read your program’s positive benefits by providing the latest at-home hormonal mouth-swab testing to ensure we are continually monitoring your progress and aware of any adverse side effects. Fill out the Medical History Form, or if you need more information, call us at (866) 224-5698 or (866) AAI-Low-T. 

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