DIM - Diindolylmethane
As we get older, the balance between testosterone and estrogen can often change, which is important for health and well-being (hormonal balance). We help our patients with their hormonal metabolism by offering them medical-grade diindolylmethane (DIM) supplements, which allow them to regain much of their quality of life.
What is DIM?
DIM or diindolylmethane naturally occurs when cruciferous vegetables (like broccoli and Brussels sprouts) are digested. Although these foods promote health, a person would have to consume at least a pound of raw vegetables per day to reach the concentrated therapeutic dose of 100 mg- 300 mg provided by our proprietary products.
Key Benefits for Our Patients
In our clinic, we utilize DIM as part of customized health programs to help relieve symptoms related to age and hormonal imbalances:
- Weight Loss or Weight Maintenance: Many people store excess body fat (especially around the abdomen, hips, and thighs) due to an imbalance in their hormonal levels. Use of DIM can help restore hormone balance and allow the body to break down and eliminate excess body fat effectively.
- Menopausal & PMS Symptoms: Most of our clients experience a decrease in menopausal symptoms such as hot flashes, night sweats, mood swings, and breast tenderness while using DIM.
- Clear Skin: Hormones (specifically androgens) and inflammation are the two main causes of hormonal acne; therefore, DIM is extremely useful for controlling this condition.
- Male Prostate Health: For men, DIM may help keep the prostate from getting too big or reproducing its cells inappropriately by eliminating estrogens from the prostate tissue.
- HRT (Hormone Replacement Therapy) Enhancement: For those taking BHRT (Bio-identical Hormone Replacement Therapy), DIM aids in utilizing the hormone replacement therapies safely and appropriately.
How Long Does it Take for DIM to Work?
As with anything new, we recommend trying a supplement/product/service for at least 3 months before warding it off. Everyone’s body is different, just as your concerns are, and DIM can take different amounts of time to work for weight loss vs hormonal acne, and so on. Some concerns may take 6 months to notice a difference.
The Mechanism: Optimizing Estrogen Pathways
Hormonal health is determined less by quantity (i.e., how much) of a hormone and more by how it is metabolized—broken down. For example, DIM acts as a “metabolic traffic cop” for estrogen metabolism and can influence our health through 3 pathways:
- The Good Pathway—DIM has been shown to promote the formation of 2-hydroxyestrone, which is a protective form of estrogen that has been linked to increased cellular health.
- The Bad Pathway—DIM inhibits the formation of 16-alpha-hydroxyestrone, which is a powerful metabolite of estrogen that is connected with increased risk for weight gain and for hormone-sensitive health problems.
- Supports testosterone in men—DIM inhibits the activity of the aromatase enzyme, which prevents the undesirable conversion of testosterone into estrogen.
Safety & Side Effects
- Common Effects: headaches, nausea, gas, as well as changing the color of your urine (these are harmless).
- Precautions: People taking high doses of DIM (greater than 600mg) may experience lower levels of sodium in their bodies. Additionally, this product does not have the approval of the FDA for any specific ailments/conditions.
- Consultation: Consult your physician before using DIM, especially if you receive HRT or if you have a history of cancer that is affected by hormones.
Why Choose AAI Rejuvenation Clinic?
At AAI, we acknowledge that your supplement needs are not going to fit everyone else’s, similar to the way your needs will not fit anyone else’s experiences. We begin by evaluating you with a detailed lab test and providing you with a telemedicine consultation with one of our doctors to see if DIM is applicable for your specific condition.
Our formulations, including DIM SGS+, are premium, formulated using science and formulated with other ingredients such as sulforaphane and pomegranate juice extract to provide antioxidants and to allow maximum assimilation of the supplements.
Get Started Today
The first step to enhancing your health is filling out our Online Medical History Form. After filling out this form, you will be assigned your own personal wellness advisor who will help guide you through your lab work and create a specific plan for you.
FAQs
While your body will start to metabolize DIM within a few hours of taking it, you should start noticing a clinical improvement (improved mood, reduction in bloating, clearer skin) within 4 to 12 weeks of taking it consistently every day.
Yes. In men, DIM inhibits the aromatase enzyme, which prevents excess testosterone from being converted to estrogen. This contributes to prostate health, the development of lean muscle mass, and proper testosterone to estrogen ratios.
A common, non-serious result of consuming DIM is urine discoloration (often referred to as ‘amber’ or ‘orange’) resulting from the presence of DIM metabolites in the body. Individuals may also experience mild nausea or headaches, which can be avoided by taking DIM with food.
For optimal absorption, it is recommended to consume DIM with food containing healthy fat. While consistency is key to succeeding with DIM, there is no specific “best time” of day to consume.