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May 20, 2018 by Joseph Fermin 0 Comments

To Understand the Hormonal Imbalance in Women 5 (4)

To Understand the Hormonal Imbalance in Women

Hormonal Imbalance

Hormonal Imbalance and why can it be so difficult or impossible to clear up acne? As you probably know, you’re hormonal and acne has a vast array of potential causes.

For some people putting cream or simple dietary changes can clear up their skin (Yeah!), but for others, it can be a long and hard arduous journey to clear up.

However, it doesn’t have to be a long struggle for clear skin if you can pinpoint the underlying triggers. Hormonal Imbalance is a cause of acne, and I’m going to talk about the topic in detail so you can understand or have an idea why this can occur, and how you can treat it!

Hormones are abundant when we are young in the body, always involved in complex and far-reaching processes. No Hormonal Imbalance acts in isolation; they work together, so when one is out of balance, it can disrupt the whole endocrine system or worse. This article will discuss Hormonal Imbalance related to pre-menstrual and acne problems.

A brief overview of the menstrual cycle in women and its Hormonal Imbalance, to understand the Hormonal Imbalance in women, it’s essential first to know what hormonal balance is and what should occur ideally.

Your period is a monthly report on your health, and if everything is in balance, you should expect to have an average length cycle, with little-to-no PMS symptoms and a painless period without heavy bleeding. You might be thinking ‘As if that exists?!’ right now, but unfortunately, so many women experience Hormonal Imbalance, stress, nutritional deficiencies, and general ill-health, that things like PMS and period pain have become the norm. PMS is common, but it’s not normal. So, let’s get into it:

Menstrual cycle will starts on the first day of your period bleed, right until the first day of your next period. An average cycle length is anywhere between 23 and 35 days in length and varies from woman to woman. Although the menstrual cycle based on 28 days, Now this is not the case always. Anything outside this 23-35 day cycle length will be considered abnormal or will often indicate a Hormonal Imbalance dysfunction along the line in life.

Hormonal Imbalance

 

There are many hormones involved in the body that can regulate the menstrual cycle, but (so it doesn’t get too confusing!) the main ones are:

  1. Estrogen
  2. Progesterone
  3. Follicle Stimulating Hormone (FSH)
  4. Luteinizing hormone (LH)
  5. Testosterone

Testosterone and other androgens, If implantation of an egg occurs, the above hormones kick in to promote all the requirements for a healthy pregnancy. If fertilization does not happen, after ovulation the uterus lining will shed to make way for a new uterine lining for next ovulation (the body is always hoping!).

Ovulation is meant to occur smack-bang in the middle of your menstrual cycle- at text-book day 14 if you have a 28-day cycle. You will usually get your period 14 days later of ovulation, so if your menstrual cycle is 25 days, you may ovulate on day 11.

The Ovulation shares the menstrual period into two stages: the first phase is when estrogen is the star, and the second stage focuses on progesterone. Progesterone usually is secreted from the ovarian follicle after ovulation (a tiny bit released from your adrenal glands), which develops into a sac called the corpus luteum. Therefore, to have adequate levels of progesterone, you need to have ovulated.

Now, central to the discussion of hormonal balance because many women don’t ovulate every menstrual cycle due to stress, illness, and nutritional inadequacies. Estrogen and progesterone-like to work together in balance, and the ratio between the levels of these hormones is critical. Estrogen is ‘proliferative,’ meaning it promotes cells growth (things like breast and hip development in puberty) and promotes smooth, plump skin, healthy bones, and arteries. Progesterone is ‘secrete,’ meaning that it promotes vascular development and the maintenance of the uterine lining after ovulation.

Hormonal Imbalance

Hormonal Imbalance can occur in women when:

  1. Estrogen levels are high or low, and progesterone is normal
  2. Estrogen levels are high or low, and progesterone is low
  3. Estrogen levels are reasonable, and progesterone levels are low
  4. Pre-Menstrual, Acne, and Estrogen levels
  5. Pre-Menstrual, Acne, and Testosterone levels

Pre-menstrual and acne can occur anywhere in the 1-2 weeks before your period, now this acne is related to the hormonal of a woman’s menstrual period and includes the hormones testosterone, estrogen, progesterone also some androgens and others.

After the ovulation, in the second part of the menstrual cycle the amount of hormones increases, because we know we have testosterone, estrogen, and progesterone. Estrogen will naturally start to decline soon while progesterone begins to rise.

But how do estrogen levels drop?

Too high or too little estrogen can disrupt the menstrual cycle and can impact progesterone levels by impairing ovulation. So, we want estrogen to be at just the right amount- not too high and not too low. Estrogen is broken down (metabolized) through the liver and eliminated via the kidneys and intestines (in your pee and poop). If estrogen is not working or metabolized correctly, then the levels build and build which can result in estrogen excess. Too much estrogen and specific metabolites of estrogen can cause inflammation. Here is where high estrogen levels can trigger pre-menstrual acne.

The cause? Too much re-circulating estrogen and not enough proper liver detoxification going on and extra estrogen can turn in testosterone.

Pre-Menstrual and acne are a sign that your liver needs some love!

Higher amounts of hormones place a higher burden on the liver’s detoxification pathways in the body. Don’t forget! The liver has to metabolize every single thing or substance that enters into our bodies food, environmental toxins, metabolic waste products, red blood cells and much more. It also metabolizes our hormones, especially estrogen (and all the estrogen metabolites).

Some are signs that your liver needs some support or attention:

  1. Headaches and migraines
  2. Constipation
  3. Acne
  4. Eczema
  5. Irritability
  6. PMS
  7. Nausea and indigestion
  8. Sinus congestion (sinusitis, rhinitis)
  9. Allergies
  10. Metabolic syndrome
  11. Insulin resistance

How can you help your liver and make sure you’re eliminating excess hormones?

Make sure you’re pooping at least once per day. If your bowels are congested, this increases your overall toxic load, which has to get processed in the liver.

Eat enough fiber- we require at least 30 grams per day, and many of us reach about half of this. Thread connects into metabolized hormones, cholesterol and moves them out of the body via the intestines. Up your intake of veggies, seeds, beans, legumes, nuts and gluten-free grains.

Cruciferous vegetables contain glucosinolates, which are broken down to indole-3-carbinol. This compound supports the detoxification of estrogens. So eat more broccoli, cauliflower, cabbage, and kale every day.

Eat bitter foods- bitter greens like the rocket (arugula), endive and bitter lettuces stimulate the production of digestive secretions, such bile in the liver. Bile contains metabolized hormones and waste products, so we make sure it leaves the body, so the liver can continually process new fresh bile and help the organization.

Include rosemary and turmeric in your diet as much as possible. This help reduces inflammation in the body, liver and also support detoxification pathways or microbiota.

Make sure you don’t have any hidden food intolerances. These will cause the body inflammation in the GIT and place an extra burden on your liver.

Balance your gut bugs! Your microbiota (intestinal bacteria) also play a significant role in metabolizing of estrogens. Consume fermented foods with each meal: fermented veggies and kombucha, yogurts, kefir, sauerkraut, and feed your bugs with probiotic fibers: green bananas, cold potatoes, whole grains, legumes, fruits, and vegetables.

Acne, Pre-Menstrual, and Progesterone testosterone, and estrogen

Now If your progesterone levels are out of balance, this can also lead to hormonal acne, as other symptoms related to PMS and infertility. Balance progesterone levels have been shown to help block the activity of DHT, and the most potent of androgens, also this present in the skin and contributes to the formation of acne.

We have discussed this earlier in this blog, progesterone mainly produced once ovulation has occurred. The egg released from a structure called the follicle, and once ovulation has occurred, the follicle forms the ‘corpus luteum,’ which is a secretory endocrine structure that produces most of our progesterone.

Progesterone, testosterone, and estrogen work together in a balanced ratio, and when this occurs there will be no more PMS symptoms, fertility will be optimal, and you will feel young. This Issues will arise when a woman fails to ovulate her self, or her body does not have the requirements to maintain and therefore her progesterone, testosterone, and estrogen levels are insufficient.

The reasons why women fail to ovulate and why?

High estrogen levels block the hormonal cascade that triggers ovulation, Polycystic ovarian syndrome (PCOS), Nutritional insufficiency, Low body fat percentage, Stress and Ovarian failure and menopause.

The Insufficient nutrients required to maintain the corpus luteum and produce hormones, Stress, and Inflammation

How can these issues be addressed and ensure we make and maintain progesterone?

We have to ensure to balance our nutritional intake in our body. The corpus luteum requires sufficient levels of magnesium, zinc, iron, B vitamins, vitamin A, vitamin C and iron (for a start).

We also need fats to make our hormones, so it is vital to include healthy fats in your diet. Manage your stress! Stress responses burn through nutrients faster than anything else, so if you chronically stressed you would be depriving your reproductive system of the nutrients, it needs to perform. Stress also inhibits the HPOA axis (hypothalamic-pituitary-ovarian axis). The hypothalamus (a master control center in your brain) needs to convinced that you are safe and nourishing for you to reproduce (which is the ultimate function of your reproductive system).

Acne can associate with insulin resistance and PCOS will primary be due to impaired glucose metabolism, so this is the critical area to address. Insulin promotes androgen production, which is a driving factor in the production of acne. Necessary but effective strategies to combat this include eliminating all refined and added sugar from your diet and eating more protein, fats and complex carbohydrates. Supplementing with chromium, magnesium and B vitamins will also support proper glucose metabolism and insulin function.

July 12, 2017 by Joseph Fermin 3 Comments

What does the Bioidentical Hormone 5 (1)

What Does the Bioidentical Hormone Program Involve

Bioidentical Hormone GHRP-2 is a synthetic analog of the peptide hormone ghrelin. Ghrelin is a small 28 amino acid peptide that is produced by the stomach in response to hunger. It also activates the human growth hormone secretagogue receptor (also known as the ghrelin receptor) to stimulate GH production and metabolism. GHRP-2 functions similarly to stimulate the hypothalamus and increase the production of endogenous GH from the pituitary gland; synthesis then slowly drops back to baseline by the third hour after administration. This more closely replicates the pulsatile nature of endogenous GH production, which makes it advantageous and potentially safer compared with synthetic HGH use.

(more…)

November 8, 2016 by Joseph Fermin 6 Comments

What are the Symptoms of Peri-menopause 5 (1)

What is the Peri-menopause?

As women, our bodies go through dramatic changes as we age, and these changes are caused by our hormones. Perimenopause is the time of a woman’s life when her hormonal cycle slows, her fertility reduces, and periods become less common as she heads toward menopause. It can be a very stressful time because it affects her physical and emotional state.

To understand what causes the peri-menopause and how to best reduce the symptoms, it is important to appreciate the changes that occur in the female body during aging. There are four main stages in a woman’s hormonal life:

Puberty

Puberty is the process of sexual maturation; it normally begins around the age of 11 and lasts for several years. Generally, it begins with breast development, followed by the growth of pubic hair and finally menstruation.

The Reproductive Years

The reproductive years begin with the onset of menstruation and persist until peri-menopause. They are characterized by the menstrual cycle, which controls a woman’s fertility. The menstrual cycle is primarily governed by fluctuations in the levels of the hormones that control ovulation and regulate the thickness of the uterine lining to prepare for the implantation of a possible fertilized egg.

  • The hypothalamus secretes gonadotropin hormone-releasing hormone (GnRH), which stimulates the pituitary gland to release follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
  • FSH stimulates follicles in the ovaries to prepare an egg for maturation and release, which includes the secretion of estrogen to prepare the uterus for implantation.
  • LH triggers ovulation, or the release of an egg from the ovaries, which results in the production and release of progesterone and additional estrogen to prepare the body for fertilization and pregnancy [1].

Menopause

Perimenopause

Perimenopause occurs when a woman’s hormonal cycle transitions toward menopause and infertility begin. It often starts in women in their late-40’s and can last for up to 11 years; the average duration is ~4 years. During the peri-menopause, menses become less common and the symptoms typically associated with menopause (discussed below) begin.

The changes that occur during menopause are caused by altered hormone levels. A woman remains fertile only as long as her ovaries produce and secrete eggs via a process known as ovulation. Since there are a finite number of eggs, female fertility essentially has an expiration date. The production of estrogen and progesterone relies upon ovulation, which means that hormone production is diminished significantly once eggs are no longer released.

Hormonally, the peri-menopause is defined by persistently increased LH and FSH levels and very low estrogen and progesterone levels. Testosterone secretion can also decline by approximately 50% during peri-menopause [2].

Menopause

Menopause officially starts one year after a woman’s last period. Menopausal women produce very high levels of FSH but low levels of estrogen and progesterone. They are no longer fertile and are at a higher risk of diseases such as osteoporosis and cardiovascular disease because of the reduced hormone concentrations [3].perimenopause

What are the Symptoms of Peri-Menopause?

The most common symptoms of peri-menopause (http://www.webmd.com/menopause/guide-perimenopause#2) are:

  • Hot flashes
  • Reduced sex drive
  • Discomfort and dryness during sex
  • Fatigue
  • Problems sleeping
  • Mood swings
  • Migraines
  • Severe premenstrual syndrome
  • Irregular periods
  • Breast tenderness
  • An urgent need to urinate
  • Urine leakage, particularly when sneezing or coughing

Because some of these symptoms can be caused by other hormone-related conditions, we always recommend getting your hormone levels checked to ensure that you receive an accurate diagnosis. If you visit AAI Rejuvenation Clinic with the above symptoms, we will measure the levels of your sex hormones as part of our work up. This will allow us to develop a specific program to make you feel like your old self.

Alleviate Your Symptoms with Hormone-Replacement Therapy (HRT)

Unfortunately, the transition from fertility to menopause is part of natural aging and it happens to all women. Although the symptoms of perimenopause can be severe, it is possible to reduce their severity and be able to function fully.

For many years, HRT was used to alleviate the symptoms of peri-menopause and reduce the risk of mortality, dementia, cardiovascular disease, and osteoporosis in aging women. Although a now-revised link to an increased risk of breast cancer led to a temporary decline in the use of HRT, it is again the number one treatment and disease-prevention strategy used in peri-menopausal and menopausal women [4].

As the name suggests, the aim of HRT is to replace the hormones no longer being produced naturally. The hormones are often delivered in tablet form, although transdermal Testosterone Patches, creams, Testosterone Gels, and implants can also be used. There are four major forms of HRT:

  • Estrogen alone
  • Estrogen and progesterone
  • Gonadomimetics, which contain estrogen, progesterone, and testosterone; an example is a tibolone
  • SERMs (selective estrogen receptor modulators)

Because HRT can restore your hormone levels to those you experienced when you were young, it can relieve your symptoms and also reduce the risk of diseases associated with low hormone levels such as osteoporosis and cardiovascular disease. Although some studies have suggested that HRT could protect against stroke, diabetes, cognitive aging, and mood, these effects are more controversial [5]. Nevertheless, the clinical evidence supporting the beneficial effects of HRT in cardiovascular disease and osteoporosis is convincing:

  • HRT reduces the risk of cardiovascular diseases. An evidence-based study investigated the evidence from randomized clinical trials and concluded that HRT could reduce the risk of mortality and cardiovascular disease in women within 10 years of the menopause aged <60 years [5]. However, there is evidence that HRT should be avoided in older women because it might increase the risk of coronary events [6].
  • HRT reduces the risk of osteoporosis. One of the best-known benefits of HRT is its ability to inhibit bone loss and reduce the incidence of fractures in perimenopausal women; estrogen therapy might be more effective than combined estrogen-progesterone treatment [7].

In addition to these clinical effects, HRT alleviates the symptoms of peri-menopause including skin and hair complaints and sexual symptoms [8], as well as hot flashes [9].

Measure your hormone levels today and find out if HRT could improve your day-to-day life.

References

  • [1] R.E. Jones, K.H. Lopez, Human reproductive biology, Academic Press2006.
  • [2] S.J. Richardson, The biological basis of the menopause, Bailliere’s clinical endocrinology and metabolism, 7 (1993) 1-16.
  • [3] L. Jia, H. Jin, J. Zhou, L. Chen, Y. Lu, Y. Ming, Y. Yu, A potential anti-tumor herbal medicine, Corilagin, inhibits ovarian cancer cell growth through blocking the TGF-beta signaling pathways, BMC complementary, and alternative medicine, 13 (2013) 33.
  • [4] R.A. Lobo, J.H. Pickar, J.C. Stevenson, W.J. Mack, H.N. Hodis, Back to the future: Hormone replacement therapy as part of a prevention strategy for women at the onset of menopause, Atherosclerosis, 254 (2016) 282-290.
  • [5] R. Sood, S.S. Faubion, C.L. Kuhle, J.M. Thielen, L.T. Shuster, Prescribing menopausal hormone therapy: an evidence-based approach, International Journal of Women’s Health, 6 (2014) 47-57.
  • [6] R.A. Lobo, Where are we 10 years after the Women’s Health Initiative?, The Journal of clinical endocrinology and metabolism, 98 (2013) 1771-1780.
  • [7] The 2012 hormone therapy position statement of The North American Menopause Society, Menopause (New York, N.Y.), 19 (2012) 257-271.
  • [8] D. Rouskova, K. Mittmann, U. Schumacher, H. Dietrich, T. Zimmermann, Effectiveness, tolerability and acceptance of an oral estradiol/levonorgestrel formulation for the treatment of menopausal complaints: a non-interventional observational study over six cycles of 28 days, Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 30 (2014) 712-716.
  • [9] N. Santoro, C.N. Epperson, S.B. Mathews, Menopausal Symptoms and Their Management, Endocrinology and metabolism clinics of North America, 44 (2015) 497-515.

October 5, 2015 by admin 0 Comments

Why Do We Age? The Reasons for Aging Explained 5 (2)

Why Do We Age? The Reasons for Aging Explained

Why do we age? This is the one question everyone wonders about but never gets an answer to. The whole Anti-Aging industry talks about everything else under the sun but avoids the question. “why do we age?” Why do they avoid it? They avoid it because they don’t know the answers. The problem is if one does not know the answer to that thorny question, a proposed treatment protocol for aging, while effective, leaves a lingering doubt in the minds of patients that something is not wholly right.

Patients may still buy a protocol, but we do not want any lingering doubts concerning anything having to do with the Anti-Aging subject. In fact the question “why do we age at all?” is so fundamentally basic that almost no patient even asks the question verbally. But, in their deeper mind, that question lingers unanswered for as long as the patient is involved in Anti-Aging and Rejuvenation.

How do I know? In 2003 I gave a questionnaire to some 400 clients with 20 questions. They were asked out of these 20 questions which one would they like answered the most? 78% checked.

Why Do We Age?, Why Do We Age? The Reasons for Aging Explained

Let us now look at some of the reasons we age.

  • Wear and tear theory. In this theory, medical scientists agree that constant use of the human body wears out its vital parts and components. Did you know that 2.5 million red blood cells die every second and are instantly replaced by another 2.5 million new red blood cells every second? The human heart must pump 2000 gallons of blood a day. In a lifetime we will pump 2 million gallons of blood, enough to fill 2 supertankers. The heart must beat 100,000 times per day…that is 35 million beats per year and over 2.5 Billion beats in the average lifetime. So the extreme repetitive use of the body simply wears out all of its parts over time. This is, without the doubt, one of the reasons the body ages, but not the only one….and not a reason that can not be overcome by the correct Anti-Aging Protocol.
  • Genes vs. Lifestyles. According to this theory of aging, your biological clock is ticking away at a predetermined rate. This theory says that your genetic DNA holds the key to your planned rate of demise from day one. Basically, this theory of aging says your genes determine everything about you including the exact age you will live to be. While there is a genetic component to aging, scientists have found that what you do with your environmental factors has a greater determination on how you will age and how long you will live.
  • Use it or lose it the theory of aging. This is a very simple theory which says the body is in need of constant daily tune-ups. So if you do not use your muscles they will atrophy and this is true. The less you use your muscles the less they will be in their peak prime condition. The less sexual activity you have the less well your sex organs will function and so on. In a way, this theory is the opposite of the wear and tear theory of aging. Without question, there is some merit to this theory. Scientists who believe in this theory even say we should allow ourselves to be exposed to germs so our immune system will get a workout and be in better shape for the long run. True enough but this theory alone does not fully explain aging even though it is a part of how we do age.
  • Short Telomere Theory of Aging. This is one of the most important discoveries ever made to the way our bodies age and why. Inside the nucleus of our cells, genes are arranged along twisted double-stranded molecules of DNA called chromosomes. At the ends of the chromosomes are stretches of DNA called telomeres, which protect our genetic data, make it possible for cells to regenerate and divide, and hold some great secrets to how we age. Telomeres have been compared with the plastic tips on shoelaces because they keep chromosome ends from fraying and sticking to each other, which would destroy our genetic information. Here is the massive problem: Each time a cell divides the telomeres get shorter… when they get too short the cell cannot regenerate anymore and dies. The telomeres in cancer cells never shorten and thus make cancer immortal cells which divide forever unless we kill them with radiation and chemo. So what we are looking for as in the starfish which is immortal and has telomeres that never shorten is the same for humans…we want to figure out how to make it so that human cells telomeres do not shorten with each cell division. One substance we have found that makes telomeres longer is HGH (Human Growth Hormone.) We have also discovered that a key component in the Ashwagandha herb, makes telomeres longer. Without question, this is a way to increase lifespan and foster better health. Both HGH and Ashwagandha work to make telomeres longer by creating the enzyme telomerase. Youthful blood levels of both Estrogen and Testosterone increase the length of telomeres by creating more telomerase. So much of what Anti-Aging protocols are doing actually eventuate in making more telomerase and thus longer telomeres. Here at AAI, we find this extremely important and exciting as we are always researching daily how to find new methods of creating longer telomeres and thus longer, healthier life.

We are just scratching the surface in the expose of what makes humans age and how to reverse that process. Here at AAI. we will continue to make new information like this available to the public as well as keeping some important discoveries private and proprietary to AAI and their clients only.

We are greatly encouraged that our longevity educational doctor; Our Dr. has discovered several additional herbs from Russia which makes the telomeres longer. Our Dr. is committed to finding enough telomere increasing substances from nature to keep all of our telomeres long enough to make a very serious contribution to increased lifespan and vigorous, perfected states of good health.

If you want to know more about how anti-aging therapies can work for you, don’t wait.

Contact AAI Rejuvenation Clinics today

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Why do we age

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