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March 5, 2019 by Joseph Fermin 0 Comments

What is Follicle Stimulating Hormone (FSH)? 5 (1)

What is Follicle Stimulating Hormone

What is Follicle Stimulating Hormone (FSH), is one of the gonadotrophic hormones, and the other being a Luteinizing Hormone (LH). The pituitary gland releases both into the bloodstream and body, and Follicle Stimulating Hormone (FSH) is one of the hormones essential for the development function of women’s ovaries and men’s testes. In women, Follicle Stimulating Hormone (FSH) stimulates the growth in the ovary before the release of an egg from one follicle to the ovulation. It also increases estradiol production. In men, Stimulating Follicle Hormone (FSH) acts on the Sertoli cells of the testes to stimulate sperm production (spermatogenesis).

How is Follicle Stimulating Hormone (FSH) control?

The release of Follicle Stimulating Hormone (FSH) is regulated by the levels of some circulating hormones released by the ovaries and testes. This system is called the hypothalamic–pituitary–gonadal axis. The gonadotropin-releasing hormone is published in the hypothalamus and the receptors in the anterior pituitary gland to stimulate both the synthesis release of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The released Follicle Stimulating Hormone (FSH) is carried in the bloodstream, where it binds to receptors in the testes and the ovaries. Using this mechanism Follicle Stimulating Hormone (FSH), along with Luteinizing Hormone (LH), can control the functions of the ovaries and testes.

follicle stimulating hormone

In women, when hormone levels are deficient, and it has complication the menstrual cycle, this is sensed by nerve cells in the hypothalamus. These cells produce the more gonadotrophin-releasing hormone, which in turn stimulates the pituitary gland to produce more Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH), and release these into the bloodstream. The rise in Follicle Stimulating Hormone (FSH) and stimulates the growth of the follicle in the ovary, and the cells of the follicles produce increasing amounts of estradiol. In turn, this production of these hormones is sensed by the hypothalamus, and pituitary gland and less gonadotrophin-releasing hormone and Follicle Stimulating Hormone (FSH) will be released, However, as the follicle grows, and more and more estrogen is produced from the follicles, it simulates a surge in luteinizing hormone (LH) and Follicle Stimulating Hormone (FSH), which stimulates the released egg from a mature follicle – ovary.

During women menstrual cycle, there is a rise the Follicle Stimulating Hormone (FSH) secretion in the first half of the period and stimulates follicular growth in the ovary, after ovulation, each month the ruptured follicle forms and Corpus luteum that produces high levels of progesterone. This inhibits the release of stimulating Follicle Stimulating Hormone (FSH), and towards the end of the cycle the Corpus luteum breaks down, and progesterone production decreases. The next menstrual period begins when Follicle Stimulating Hormone (FSH) starts the production again, and get back to normal…

follicle stimulating hormone

Now In men, the production of Follicle Stimulating Hormone (FSH) is regulated by levels of testosterone and inhibin, both produced by the testes. Follicle Stimulating Hormone (FSH) regulates testosterone levels and when this rise they are sensed by nerve cells in the hypothalamus so that gonadotropin-releasing hormone secretion and consequently Follicle Stimulating Hormone (FSH) is decreased. The opposite occurs when testosterone levels drop. This is known as a ‘Negative Feedback in the body’ control so that the production of testosterone remains steady. But the sensed by cells in the anterior pituitary gland rather than the hypothalamus.

What happens if you have too much Follicle Stimulating Hormone (FSH)?

Most often, and raised levels of Follicle Stimulating Hormone (FSH) are a sign of malfunction in the ovary or testis. If the gonads fail to create enough estrogen, testosterone and inhibit, the right feedback control of Follicle Stimulating Hormone (FSH) production from the pituitary gland is lost, and the levels of both Follicle Stimulating Hormone (FSH) will rise. This condition is called hypogonadotropic-hypogonadism and is associated with primary ovarian failure or testicular failure. This is seen in states such as Klinefelter’s syndrome in men and Turner syndrome in women.

In women, Follicle Stimulating Hormone (FSH) levels also start to rise naturally in women around the menopausal period, reflecting a reduction in the function of the ovaries and decline of estrogen and progesterone production.

There are rare pituitary conditions that can raise the levels of Follicle Stimulating Hormone (FSH) in the bloodstream. This overwhelms the regular negative feedback and can cause ovarian hyperstimulation syndrome in women ovaries.

Symptoms: This includes enlarging of the ovaries and potentially dangerous accumulation of fluid in the abdomen, and triggered the rise in ovarian steroid output. Which leads to pain and other problems in the pelvic area of the body.

What happens if don’t produce enough Follicle Stimulating Hormone (FSH)?

In women, lack of Follicle-Stimulating-Hormone (FSH) leads to incomplete development in puberty o poor ovarian function (ovarian failure), and In this situation ovarian follicles do not grow properly and do not release in the egg, thus leading to infertility. Since levels of Follicle-Stimulating-Hormone (FSH) in the bloodstream are low, this condition is called hypogonadotropic-hypogonadism. This condition is called Kallman’s syndrome, which is associated with a reduced sense of smell.

Sufficient Follicle-Stimulating-Hormone (FSH), this action is also needed for proper sperm production in men, in case of complete absence of Follicle Stimulating in men, and the lack of puberty and infertility due no production of sperm is called (azoospermia). Partial Follicle-Stimulating-Hormone (FSH) deficiency in young men, can also cause delayed puberty and low sperm production, called (oligozoospermia), but fathering a child may still be possible. Follicle-Stimulating-Hormone (FSH) occurs after puberty; there will be a similar loss of fertility…

October 25, 2018 by Joseph Fermin 0 Comments

Male Menopause or Low-T is No longer Just for Older Men 0 (0)

Male Menopause or Low Testosterone, In our practice of low hormones, I’ve noticed that there is an increasing number of younger guys, as much as older men are complaining of sexual concerns and problems, like diminished libido and erectile difficulties.

Does some clinician believe that factors like obesity, stress and inadequate sleep probably play a role in such issues in the production of your hormones, and isn’t purely a lifestyle problem or question? These factors are also common or possible causes of low levels of testosterone, which can influence the role of sexual function problems.

book-free

Low Testosterone” is still most common in men over 30, also known male menopause or andropause, as you gradual testosterone decrease in testosterone typically occurs steadily over time. In fact, “after age 30, men experience a 3% reduction in testosterone every year,” the naturopathic doctor said. “According to Michael A. Werner, MD, a specialist in male infertility, erectile dysfunction and sexual dysfunction, male menopause or andropause occurs in 2% to 5% of men ages 40 to 49, rises to 6% to 30% in men ages 50 to 59, reaches 20% to 45% in men 60 to 69, and is found in up to 70% of men of ages 70 to 79 experience andropause with low testosterone.”

So that being said, low testosterone isn’t necessarily just a consequence of aging. Some factors can have an impact on a man’s testosterone levels. Low Testosterone has many factors influence sexual health, including mood, energy level, nutrition, genetics, age, health conditions, and medications, and more commonly seen in older men or such as:

Motivation: As testosterone production declines so do energy-boosting components and restful sleep, thus producing decreased motivation.

libido: Low levels of testosterone cause a reduction in sex drive.

Depression: When a person experiences low testosterone levels it alters hormone production, which can lead to depression.

Erectile Dysfunction: Testosterone supplementation can be used to reverse or correct low testosterone-induced erectile dysfunction.

Fatigue: A decrease in testosterone levels leads to hormonal changes, which can cause fatigue, also can be exacerbated by low testosterone-induced sleep loss, which can quickly turn into a vicious cycle.

High Cholesterol: High cholesterol is a silent killer that can lead to a variety of heart conditions. Testosterone injections, when used in a proper protocol, can lower cholesterol, blood pressure, and triglyceride levels.

Low Energy & Fatigue: Symptoms of aging can be a direct result of diminishing levels of testosterone or (Low-T) in the body. As we age, our bodies produce less and less testosterone, causing low energy and fatigue.

Memory Loss: Some recent evidence suggests that testosterone might help prevent and treat the effects of brain aging. Some patients treated with testosterone injections expressed a palpable increase in their cognitive function, short- and long-term memory, and vocabulary improvements.

Thyroid: The hormones produced by the thyroid and adrenal glands regulate vital processes throughout the body. If thyroid hormone and cortisol levels are abnormal, the rest of the body does not function properly. Some studies have suggested a link between low thyroid function and low testosterone levels.

Weight Gain: The production of certain hormones decreases after the age of 30. The lean body mass of some organs also starts to decline, whereas fat mass increases. Testosterone administration can affect your body composition.

One option for low testosterone is prescription is testosterone replacement therapy (TRT), “Testosterone, like all hormones, has multiple actions on many body functions and the mind,” that being said.

“In my opinion, it should be taken — and prescribed — only to correct a deficiency documented by appropriate blood tests.” Otherwise, We recommend “an integrative approach to sexual health” that assesses all the many factors that affect testosterone.

November 13, 2017 by Joseph Fermin 0 Comments

An Inside Look at Testosterone Injections Therapy 0 (0)

Inside Look Testosterone Injections Therapy

testosterone injections therapyTESTOSTERONE INJECTIONS THERAPY

Testosterone is an essential factor in males, that does more for men than just promote sex drive. Low Testosterone levels decline as a part of healthy aging and are the cause of several physiological changes. Low Testosterone level symptoms include;

1) Reduced Motivation
2) Erectile Dysfunction
3) Loss of Libido or sex drive
4) Fatigue and low energy
5) Increased Cholesterol Levels
6) Memory and Concentration
7) Decreased Muscle Mass
8) Thyroid Dysfunction and more

Since these symptoms are common in low testosterone, physicians will often include hormone levels as part of routine blood work. Normal levels of testosterone are between 300 and 1,000 ng/dL. If a blood test shows that your levels are far below the norm, your doctor may suggest testosterone injections. The treatment is called TRT.

SYMPTOMS OF LOW TESTOSTERONE

Most men naturally start losing testosterone when they hit their 30’s. (low T). Common symptoms of low Testosterone include:

1) Erectile dysfunction (ED)
2) Changes in sex drive
3) Decreased sperm count
4) Depression or anxiety
5) Weight gain
6) Hot flashes

TESTOSTERONE AND DIAGNOSIS

Many men may want to diagnose themselves with a testosterone kit. The problem with self-diagnosis is that many of the symptoms of low Testosterone are healthy parts of aging. So using it for diagnosis isn’t reliable. Our doctor may order testosterone blood test. It is the only way to find out if you have low testosterone.

To get a perfect reading our doctor will take a look at your health history, physical exam and blood test to measure your testosterone levels. You’ll also likely have a test that measures your red blood cell count.

POTENTIAL BENEFITS OF TESTOSTERONE INJECTIONS THERAPY 

The purpose of Testosterone Injections Therapy is to help regulate hormone levels and to help address problems related to low Testosterone. For men with low Testosterone, the benefits of these injections can include:

1)  Motivation and Memory Loss
2)  Sex Drive & Desire
3)  Depression and Energy
4)  Cholesterol and Osteoporosis
5)  Erectile Dysfunction
6)  Muscle Mass and Better Sleep
7)  Wounds healing & Illness
8)  Thyroid Dysfunction and more

TESTOSTERONE CAN HELP WITH FAT AND MUSCLE CHANGES

Men have less body fat than women; This is partly related to testosterone, which regulates the fat in the body and muscle maintenance in your body. You’ll likely also notice an increase in body fat, especially around your midsection.

Your hormones also help regulate muscle growth. So, with low Testosterone, you may feel like you’re losing muscle size or strength.

Testosterone shots regulate fat distribution, but you shouldn’t expect significant weight loss changes from hormone therapy alone, without exercise. As for maintenance of muscle, testosterone therapy has been found to improve increase muscle mass, but not strength.

TESTOSTERONE INJECTIONS THERAPY AND SPERM COUNT

Low sperm count in men is a common side effect of low Testosterone. This problem can make it difficult to get your partner pregnant.

TESTOSTERONE INJECTIONS THERAPY AND THE BOTTOM LINE

Testosterone injections therapy can only be helpful If you just have low Testosterone. If you’re wondering if testosterone is a right choice for you, ask your doctor. They can test you for low Testosterone. Ask your doctors, or Give us a call, if testosterone injections therapy would be a good choice for you.

If you don’t end up having low Testosterone but still feel like your hormone levels might be off, keep in mind that proper Food, Regular exercise, could help you increase testosterone naturally and make you feel better. If that doesn’t help, be sure you contact us for help.

November 2, 2017 by Joseph Fermin 0 Comments

What Causes Low Testosterone and The Role Of Testosterone 0 (0)

What Causes Low Testosterone

The Danger of Low Testosterone, Risks Associated with Low hGH in Men, HGH Side Effects, What Causes Low Testosterone

What is the role of testosterone?

Causes Low Testosterone is the most critical hormone in men. Low, testosterone (hypogonadism) can cause and is responsible for the male characteristics & helps maintain our sex drive, sperm production, body hair, bone, and muscle.

What’re other causes low testosterone?

(e.g., trauma, castration, radiation or chemotherapy), hormonal disorders like (pituitary tumors or diseases, high levels of prolactin), or other disorders like (chronic liver and kidney disease, HIV/AIDS, too much body fat, and type 2 diabetes and associated obesity).

How is low testosterone diagnosed and tested?

Your doctor will use blood tests to see if the total testosterone level is within the normal range. Will be 300 to 1,000 ng/dL, but this may differ depending on the laboratory and a physical exam, To diagnose low testosterone, you may need more than one early-morning (7 AM — 10 AM) blood test and, sometimes, other analyses of the pituitary gland.

How is low testosterone treated?

There are several methods of testosterone replacement; Testosterone Injections is the best meted to get the full benefits of the therapy:

• Injections
• Patches
• Gel
• Pellets

The best method will depend on the cause of the problem, the patient’s preference and tolerance, and cost.

What should you do with this information?

If you have symptoms talk with one of our specialist, an expert in hormones, can help you determine the causes. Be open with our doctor about your medical history, all prescription and nonprescription drugs, any sexual problems, and any significant changes in your life.

Many lifestyle choices and decisions can also negatively impact our natural testosterone production, including:

• Injury to the body. Any physical or psychological trauma can significantly hinder the natural production of testosterone in men.

• Getting married or having children. High testosterone in men prepares us to find a mate and have a family.

Once those goals have been met, our bodies are programmed to lower testosterone production:

• Depression
• Excessive drug use
• Excessive marijuana use
• Extreme opiate use
• Excessive alcohol consumption
• High-stress levels
• Lack of sleep or good quality sleep
• Low self-esteem
• Negative thoughts
• Unnatural glandular issues
• And much, much more…

Low Hormone Symptoms also will depend on the cause of the problem:

  • Weight Gain

Causes Low Testosterone Once we hit age 30 the levels of many of our hormones begin to decline. The lean body mass (LBM) of our organs starts to decrease, whereas the adipose (or fat) mass. Between the ages of 30 and 75, the liver, kidneys, brain, and pancreas atrophy by an average of 30%. The LBM declines by ~5% in men and 2.5% in women per decade. Meanwhile, the percent of body fat increases in both sexes during the same period.

  • Depression

Depression impacts all of us at one time or another. It simply isn’t possible to have everything go well all the time. Plenty of people may seem to be lucky and prosperous, with the world at their fingertips. Sadly, that surface appearance completely masks the symptoms of low motivation and/or depression. Depression can hit you like a ton of bricks. The stigma associated with being a man with symptoms of depression can be even more demoralizing and add insult to injury. Most men refuse to admit to feelings of depression, let alone confront or deal with the causative issues.

  • Muscle Mass and Strength

Once we hit 30, the lean body mass of our organs begins to decrease, whereas the fat mass increases. Between the ages of 40 and 80, the lean body mass declines by ~5% per decade in men and 2.5% per decade in women. Meanwhile, at the same time, the body fat in both sexes increases. These physiological changes are not just an affront to vanity but are a threat to health and longevity. First, aerobic power is directly connected to the amount of lean body mass. Second, this shrinkage of vital organs means that they cannot do their jobs as well, whether it be the heart pumping, the muscles lifting, or the kidneys clearing metabolic waste from the blood. Third, the risk of heart attack, hypertension, and diabetes with an increasing abdominal fat mass.

  • Fatigue

We all have busy lives and are constantly on the go. Although most people experience sleep problems at some point in their life, one can usually identify the cause of the temporary tiredness and remedy it quickly with good quality rest. Extreme, long-term fatigue is a different story. You do not know what is causing it, and it can gradually destroy your motivation, concentration, and energy levels. Often, the people in your life do not understand what how debilitating fatigue can be.

  • Sleep Disturbances

Sleep disturbance affects every facet of our existence. Many sleep-related problems can be overcome with testosterone therapy. Men with lower testosterone levels have reduced sleep efficiency, with increased nocturnal awakenings and less slow-wave (REM) sleep. Studies have even shown that sleep disturbance caused by sleep apnea, a chronic breathing problem, may be linked to low testosterone levels.

  • Erectile Dysfunction

One of the worst aspects of getting older is erectile dysfunction (ED), which causes a reduced ability to perform in the bedroom and lowers your sex drive. One of the main causes of age-related sexual dysfunction is the changes in your metabolism and hormone levels, including reduced testosterone production. Numerous studies have also linked low GH and IGF-I levels to ED.

  • Decreased Sex Drive and Desire

Low testosterone often leads to a decreased sex drive. Although it is the dominant hormone in men, testosterone also plays a significant role in women. Contrary to popular belief, low libido is not related to the frequency of sexual activity or the amount of satisfaction achieved. Instead, it is determined by the body’s signal indicating sexual desire. This signal declines with age due to the body’s decreased production of testosterone.

  • Motivation

Motivation is important for getting the most out of life; without motivation, even the most routine task can be daunting. Many people to assume if they get a good night sleep they will feel rejuvenated in the morning. When you wake your head is immediately flooded with thoughts of what you need to accomplish during the day, even if you sleep well. You might then organize your day, plan your activities, and create a map of the tasks you need to accomplish in order to have a productive day. However, if you do not have motivation then all the preparation in the world will not help you execute your plan for a productive day.

  • High Cholesterol

Undetected and untreated high cholesterol is a silent killer! High Cholesterol can lead to an assortment of different health problems, including heart attack, stroke, and death. Although high cholesterol is associated with overweight individuals, you can be thin and still have high cholesterol. GH is an important regulator of LDL and total cholesterol, as well as triglycerides. It lowers diastolic blood pressure by reducing the resistance of arteries and capillaries that carry blood throughout the body. Multiple studies have shown that GH can reduce levels of LDL, or bad, cholesterol.

  • Low Energy

Many symptoms of aging are a direct or indirect result of diminishing GH and testosterone levels, including low energy and fatigue. By the age of 30, most people are GH-deficient, which can result in somatotropin deficiency syndrome (SDS). Somatotropin is another name for GH. Without GH therapy, GH levels continue to decline, which is sometimes referred to as the somatopause.

  • Memory Loss

Hopefully, you have been skimming through the many pages of our website to try and educate yourself about how to take charge of your life, maximize your potential, and experience life to the fullest. The only way you will ever be able to do this is if you are feeling your best, are able to produce your best, and give your best!

  • Osteoporosis and Bone Mass

Osteoporosis is the gradual thinning that makes bones brittle and porous which in turn makes them more prone to fracture. If affects approximately 10 million adults in the United States, and is more common in women than men. Of people older than 50 years of age, one in two women and one in eight men are predicted to have an osteoporosis-related fracture in their lifetime. Individuals of Caucasian and Asian ethnicity are also at a high risk.

  • Wound Healing

Think about your children or yourself when you were a child. Do you remember how many times you fell down and scraped your knee? Your arms and legs always seemed to be wearing red badges of courage. Then, a scab would form and then soon disappear, leaving absolutely no trace of the injury. However, when you are young your cells regenerate and repair at a much faster pace, and so your wounds heal more quickly and your bones knit more rapidly. All these processes are under the control of GH and other growth factors. Although GH supplementation won’t restore your healing capacity to that you experienced as a child, it will dramatically accelerate the healing process.

  • Thyroid

The thyroid and adrenal glands regulate multiple functions throughout the body. If thyroid hormone and cortisol levels are not right, the rest of the body will not function correctly; these critical hormones are just as important as estrogen, progesterone, testosterone, and growth hormone.

(more…)

August 1, 2016 by admin 0 Comments

Durian Fruit 4 (1)

Durian Fruit: Ever Heard of It?

Durian is a species of fruit that is native to Southeast Asia. Every species of Durian is made up of 5% fat. The glycemic index of this fruit is 44, which happens to be lower than a papaya’s. This is mainly due to the oil slowing down its sugar-burn time.

  • • Durian tastes like custard ice-cream. Durian
  • • Maximum serving should be no more than 100g a day.
  • • Only has about 25g of fat.
  • • Sugar propels yellow phytochemicals and rich sulfur into the cell walls to be absorbed.
  • • One of the very few fruits with high in B vitamins.
  • • 4g of fiber.
  • • A special power to heal and cleanse stomach if eaten before any other food.
  • • Two types of Durian: Canary yellow and cream.
  • • Species known as D 22 has a better flavor and 25% more saturated fats (Palmitic acid) than other types.
  • • Durian’s fat content level is 50% Omega– 9 Oleic acid, classified as an “Organoleptic Oil”. It is also found an avocado, olive oil and virtually all tree nuts.
  • • Durian has less saturated fat than 1-tablespoon of butter.

Healthy Stomach, Calm Mind

DurianDurian contains high levels of Tryptophan. When consumed on an empty stomach it has a significant boosting effect on serotonin. Tryptophan is an amino acid (bioavailable fruit protein) that helps make a brain neurotransmitter of higher consciousness.

  • Tryptophan incites the body’s production of Serotonin, which promotes a calm, content state of mind. The more serotonin a person has in their body, the happier they feel.
  • Durian also helps with the production of the hormone Melatonin.
  • Serotonin and melatonin are both hormones that manage emotions.

This combination can help relieve:
~ Anxiousness
~ Sleeplessness
~ Depressive disorders

  • Tyrosine, an amino acid that, on its own, assists with relieving stress and sleeping disorders, is also found in Durian.
  • Durian is a nitric oxide (NO) enhancer. It has a phytochemical called Harmaline, a well-documented MAO inhibitor.

An elevated body warmth may be experienced after consuming Durian resulting from its rare spectrum of amino acids thatDurian

combine with some intense, Naturals sugars. This helps fats and minerals to be delivered to your brain instantly. Some reference it comparable to a euphoric rush. Bear in mind, this happens only when eaten on an empty stomach.

  • Urine may smell like durian as one detoxifies, similar to asparagus.

Durian contains sulfur, which produces a very strong smell. However, for the same reason, it has impressive detoxifying superpowers. Sulfur is the third most abundant mineral in our body and liver glutathione needs sulfur to become active and detoxify.

Durian Has:

  • • Yellow lutein for the eyes
  • • Smooth fatty substances
  • • Divine sweet taste to explore.
  • • Properties for better digestion (Thiamin – 61%)
  • • Properties to normalize blood sugar levels (Manganese – 39%)
  • • Properties to help fight emotional instability (Vitamin B6 – 38%)
  • • Properties to help evade and relieve constipation (Fiber – 37%)
  • • Protection for future healthy bones (Potassium – 30%)
  • • Properties for migraine alleviation (Riboflavin – 29%)
  • • Thyroid protecting properties (Copper – 25%)
  • • Properties to help promote a healthy pregnancy (Folate – 22%)
  • • Properties to help relax muscles and nerves (Magnesium -18%)Durian
  • • Properties to help fight the development of anemia (Folate)
  • • Properties that Promote healthy gums and teeth (Phosphorous)
  • • Vitamins essential to the body. (mainly iron, dietary fiber, potassium, vitamin C, and vitamin B complex.

Durian Also Has:

  • • Properties that lower cholesterol (Omega’s and fatty acids)
  • • Blood Detoxification properties (Sulfur)
  • • Properties to help build muscles.
  • • Properties to help Improve sexual function.
  • • Anti-inflammatory properties.
  • • Antioxidant Activity.
  • • Mosquito repellent potential (Husk)
  • • Properties to encourage stronger immune system (antioxidant, vitamin-rich)
  • • Better energy promoting properties
  • • Properties to Promote healthy skin (Vitamin C – 80%)
  • • Properties to help prevent premature aging (antioxidant and vitamin-rich, and detoxifies blood)
  • • Natural sleeping pills affect (Promotes release of Serotonin and Melatonin)
  • • Properties to help with preventing cancer, diabetes, heart disease and inhibit tumor growth (specific phytosterol ingredients)
  • • Cognitive function aiding properties
  • • Properties for avoiding Morning Sickness.
  • • Properties to help alleviate stress (Serotonin, Melatonin)
  • • Properties for a Strong protection from harmful effects of free radicals. (Intense combination of amino acids)

Testosterone Injections – Curious about testosterone injections Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698

If you are interested in more information or would like to know about the requirement for qualifying for hGH, testosterone therapy or any other hormone-related program, please fill out our short form or call us at:

February 4, 2016 by admin 0 Comments

Testosterone Cypionate Description 0 (0)

Testosterone Cypionate description injections

Testosterone Cypionate Description injection for intramuscular injection contains Testosterone Cypionate which is the oil-soluble 17 (beta)- cyclopentyl propionate ester of the androgenic hormone testosterone. Testosterone Cypionate is a white or creamy white crystalline powder, odorless or nearly so and stable in air. It is insoluble in water, freely soluble in alcohol, chloroform, dioxane, ether, and soluble in vegetable oils. The chemical name for Testosterone Cypionate is androst-4-en-3-one,17-(3-cyclopentyl-1-oxopropoxy)-, (17β)-. Its molecular formula is C27H40O3, and the molecular weight 412.61.

The structural formula is represented below:

Testosterone Cypionate injection, USP is available in two strengths, 100 mg/mL and 200 mg/mL Testosterone Cypionate, USP.

Each mL of the 100 mg/mL solution contains:

Testosterone Cypionate……………………………………………………………………. 100 mg
Benzyl benzoate ……………………………………………………………………………… 0.1 mL
Cottonseed oil ………………………………………………………………………………… 736 mg
Benzyl alcohol (as preservative)………………………………………………………… 9.45 mg

Each mL of the 200 mg/mL solution contains:

Testosterone Cypionate……………………………………………………………………. 200 mg
Benzyl benzoate………………………………………………………………………………. 0.2 mL
Cottonseed oil………………………………………………………………………………… 560 mg

Benzyl alcohol (as preservative)………………………………………………………… 9.45 mg

Testosterone Cypionate – Clinical Pharmacology

Endogenous androgens are responsible for normal growth and development of the male sex organs and for maintenance of secondary sex characteristics. These effects include growth and maturation of the prostate, seminal vesicles, penis, and scrotum; development of male hair distribution, such as beard, pubic, chest, and axillary hair; laryngeal enlargement, vocal cord thickening, and alterations in body musculature and fat distribution. Drugs in this class also cause retention of nitrogen, sodium, potassium, and phosphorous, and decreased urinary excretion of calcium. Androgens have been reported to increase protein anabolism and decrease protein catabolism. Nitrogen balance is improved only when there is sufficient intake of calories and protein.

Androgens are responsible for the growth spurt of adolescence and for eventual termination of linear growth, brought about by fusion of the epiphyseal growth centers. In children, exogenous androgens accelerate linear growth rates but may cause a disproportionate advancement in bone maturation. Use over long periods may result in fusion of the epiphyseal growth centers and termination of the growth process. Androgens have been reported to stimulate the production of red blood cells by enhancing production of erythropoietic stimulation factor.

During exogenous administration of androgens, endogenous testosterone release is inhibited through feedback inhibition of pituitary luteinizing hormone (LH). At large doses of exogenous androgens, spermatogenesis may also be suppressed through feedback inhibition of pituitary follicle stimulating hormone (FSH).

There is a lack of substantial evidence that androgens are effective in fractures, surgery, convalescence, and functional uterine bleeding.

Pharmacokinetics

Testosterone esters are less polar than free testosterone. Testosterone esters in oil injected intramuscularly are absorbed slowly from the lipid phase; thus, Testosterone Cypionate can be given at intervals of two to four weeks.

Testosterone in plasma is 98 percent bound to a specific testosterone-estradiol binding globulin, and about 2 percent is free. Generally, the amount of this sex-hormone binding globulin in the plasma will determine the distribution of testosterone between free and bound forms, and the free testosterone concentration will determine its half-life.

About 90 percent of a dose of testosterone injections is excreted in the urine as glucuronic and sulfuric acid conjugates of testosterone and its metabolites; about 6 percent of a dose is excreted in the feces, mostly in the unconjugated form. Inactivation of testosterone occurs primarily in the liver. Testosterone therapy is metabolized to various 17-keto steroids through two different pathways.

The half-life of Testosterone Cypionate, when injected intramuscularly, is approximately eight days.

In many tissues, the activity of testosterone therapy appears to depend on reduction to dihydrotestosterone, which binds to cytosol receptor proteins. The steroid-receptor complex is transported to the nucleus where it initiates transcription events and cellular changes related to androgen action.

Indications and Usage for Testosterone Cypionate description

Testosterone Cypionate description injection is indicated for replacement therapy in the male in conditions associated with symptoms of deficiency or absence of endogenous testosterone.

  • Primary hypogonadism (congenital or acquired)-testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome; or orchidectomy.
  • Hypogonadotropic hypogonadism (congenital or acquired): gonadotropin or LHRH deficiency, or pituitary-hypothalamic injury from tumors, trauma, or radiation.

Safety and efficacy of Testosterone Cypionate description in men with “age-related hypogonadism” (also referred to as “late-onset hypogonadism”) have not been established.

Contraindications

  1. Known hypersensitivity to the drug
  2. Males with carcinoma of the breast
  3. Males with known or suspected carcinoma of the prostate gland
  4. Women who are or who may become pregnant
  5. Patients with serious cardiac, hepatic or renal disease

Warnings

Hypercalcemia may occur in immobilized patients. If this occurs, the drug should be discontinued.

Prolonged use of high doses of androgens (principally the 17-α alkyl-androgens) has been associated with the development of hepatic adenomas, hepatocellular carcinoma, and peliosis hepatis —all potentially life-threatening complications.

Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking.

There have been postmarketing reports of venous thromboembolic events, including deep vein thrombosis (DVT) and pulmonary embolism (PE), in patients using testosterone products, such as Testosterone Cypionate description. Evaluate patients who report symptoms of pain, edema, warmth, and erythema in the lower extremity for DVT and those who present with acute shortness of breath for PE. If a venous thromboembolic event is suspected, discontinue treatment with Testosterone Cypionate description and initiate appropriate workup and management.

Long term clinical safety trials have not been conducted to assess the cardiovascular outcomes of testosterone replacement therapy in men. To date, epidemiologic studies and randomized controlled trials have been inconclusive for determining the risk of major adverse cardiovascular events (MACE), such as non-fatal myocardial infarction, non-fatal stroke, and cardiovascular death, with the use of testosterone compared to non-use. Some studies, but not all, have reported an increased risk of MACE in association with the use of testosterone replacement therapy in men. Patients should be informed of this possible risk when deciding whether to use or to continue to use Testosterone Cypionate description.

Edema, with or without congestive heart failure, may be a serious complication in patients with preexisting cardiac, renal or hepatic disease.

Gynecomastia may develop and occasionally persists in patients being treated for hypogonadism.

The preservative benzyl alcohol has been associated with serious adverse events, including the “gasping syndrome”, and death in pediatric patients. Although normal therapeutic doses of this product ordinarily deliver amounts of benzyl alcohol that are substantially lower than those reported in association with the “gasping syndrome”, the minimum amount of benzyl alcohol at which toxicity may occur is not known. The risk of benzyl alcohol toxicity depends on the quantity administered and the hepatic capacity to detoxify the chemical. Premature and low-birth weight infants may be more likely to develop toxicity.

Androgen therapy should be used cautiously in healthy males with delayed puberty. The effect on bone maturation should be monitored by assessing the bone age of the wrist and hand every 6 months. In children, androgen treatment may accelerate bone maturation without producing a compensatory gain in linear growth. This adverse effect may result in compromised adult stature. The younger the child the greater the risk of compromising final mature height.

This drug has not been shown to be safe and effective for the enhancement of athletic performance. Because of the potential risk of serious adverse health effects, this drug should not be used for such purpose.

Precautions

General

Patients with benign prostatic hypertrophy may develop acute urethral obstruction. Priapism or excessive sexual stimulation may develop. Oligospermia may occur after prolonged administration or excessive dosage. If any of these effects appear, the androgen should be stopped and if restarted, a lower dosage should be utilized.

Testosterone Cypionate description should not be used interchangeably with testosterone propionate description because of differences in duration of action.

Testosterone Cypionate description is not for intravenous use.

Information for Patients

Patients should be instructed to report any of the following: nausea, vomiting, changes in skin color, ankle swelling, too frequent or persistent erections of the penis.

Laboratory Tests

Hemoglobin and hematocrit levels (to detect polycythemia) should be checked periodically in patients receiving long-term androgen administration.

Serum cholesterol may increase during androgen therapy.

Drug Interactions

Androgens may increase sensitivity to oral anticoagulants. The dosage of the anticoagulant may require a reduction in order to maintain satisfactory therapeutic hypoprothrombinemia.

Concurrent administration of oxyphenbutazone and androgens may result in elevated serum levels of oxyphenbutazone.

In diabetic patients, the metabolic effects of androgens may decrease blood glucose and, therefore, insulin requirements.

Drug/Laboratory Test Interferences

Androgens may decrease levels of thyroxine-binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction.

Carcinogenesis

Animal data

Testosterone has been tested by subcutaneous injection and implantation in mice and rats. The implant induced cervical-uterine tumors in mice, which metastasized in some cases. There is suggestive evidence that injection of testosterone into some strains of female mice increases their susceptibility to hepatoma. Testosterone is also known to increase the number of tumors and decrease the degree of differentiation of chemically induced carcinomas of the liver in rats.

Human data

There are rare reports of hepatocellular carcinoma in patients receiving long-term therapy with androgens in high doses. Withdrawal of the drugs did not lead to regression of the tumors in all cases.

Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking.

Pregnancy

Teratogenic Effects

Pregnancy Category X. (See CONTRAINDICATIONS)

Benzyl alcohol can cross the placenta. See WARNINGS.

Nursing Mothers

Testosterone Cypionate description is not recommended for use in nursing mothers.

Pediatric Use

Safety and effectiveness in pediatric patients below the age of 12 years have not been established.

Adverse Reactions

The following adverse reactions in the male have occurred with some androgens:

Endocrine and urogenital: Gynecomastia and excessive frequency and duration of penile erections. Oligospermia may occur at high dosages.

Skin and Appendages: Hirsutism, male pattern of baldness, seborrhea, and acne.

Cardiovascular Disorders – myocardial infarction, stroke

Fluid and electrolyte disturbances: Retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates.

Gastrointestinal: Nausea, cholestatic jaundice, alterations in liver function tests, rarely hepatocellular neoplasms and peliosis hepatis (see WARNINGS).

Hematologic: Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy, and polycythemia.

Nervous system: Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia.

Allergic: Hypersensitivity, including skin manifestations and anaphylactoid reactions.

Vascular Disorders: venous thromboembolism

Miscellaneous: Inflammation and pain at the site of intramuscular testosterone injection.

Testosterone Therapy Information

September 21, 2015 by Joseph Fermin 1 Comment

L-Carnitine Health Benefits 3 (1)

L-Carnitine Health Benefits

  • Fat Burner: L-Carnitine is to the human body what a turbo mechanism is a high-performance automobile. It’s an essential amino acid with vitamin-like qualities for optimum fat burning.
  • Muscle builder: Supplementing with l-Carnitine can help increase strength and heavier weights eventually mean a better-defined physique.
  • Bone Mass: Slows down the bone loss process and improves bone microstructural properties by decreasing bone turnover.
  • Improves Cardio system: L-Carnitine is vital for maintaining a healthy cardiovascular system and can be used along with conventional treatment for angina to reduce the needs for medicine and improve the ability of those with angina to exercise without chest pain or discomfort.
  • Male infertility: Helps improve both sperm count and quality of sperm.
  • Type II Diabetes: Helps diabetics by increasing glucose oxidation, glucose storage, as well as glucose uptake.
  • Immune System: Serves as an antioxidant that can help prevent damage done to your healthy cells by free radicals. This can help you out when you have a cold or are dealing with various seasonal allergies and/or training.
  • Brain Function: Helps protect the brain from both age-related and stress-related damage, which helps it function longer and better.

L-Carnitine Health Benefits

This medication is usually compounded with other amino acids in an effort to maximize the benefits and end results. However, when it’s administered on its own, it’s usually in an effort to use the medication to stimulate weight loss. The patient’s prescribing physician will determine the exact dosage and protocol.

Typically, on its own, L-Carnitine Health Benefits is administered on a daily basis or, at least every other day. If it’s compounded with other amino acids or formulations, then the protocol can vastly vary.

Our L-Carnitine Health Benefits comes in 10ml vials and does not need to be stored in a refrigerated unit. As long as it is kept in a cool, dry spot there should be no issues with its efficacy.

**NOTE**  The content contained in this blog is subject to interpretation and is the opinion of the content writer.  We do not claim it to be fact.  We encourage you to consult a medical doctor before taking any prescribed medications or supplements.

July 27, 2015 by Joseph Fermin 2 Comments

Can a Change in Hormones Cause Chronic Fatigue? 5 (1)

Could The Hormone explain
Your Chronic Fatigue?

Men experience a slow, yet steady decline in testosterone as they age. The continued loss of this male sex hormone is sometimes referred to as male menopause or andropause. Similar to female menopause, hormonal changes come with a number of undeniable symptoms, including Chronic Fatigue. These changes are not easy to accept or notice, however, they can have a gradual, crippling feeling.

Testosterone injections play a vital role in the body’s immune response. As testosterone levels decline, the body compensates by redistributing energy and resources to the immune system. This takes a considerable toll on energy levels resulting in testosterone-related Chronic Fatigue.

Additionally, another potential relationship between free testosterone and Chronic Fatigue is sleep disruption. It isn’t uncommon for a drop in testosterone levels to cause sleep disruptions in men and women. Testosterone is naturally released into the body in different periods throughout the day. However, it is mainly produced at night when you sleep. Usually, most production occurs approximately 3 hours into your sleep cycle. You probably get little to no quality sleep if you are suffering from low testosterone. Sleep deprivation causes your natural along with all the vigorous attributions associated with it.

The loss of energy, lack of sleep, Chronic Fatigue and other symptoms linked with diminishing testosterone levels is not something you have to incorporate into your lifestyle. Fortunately, this can be improved. Here at AAI, we delve deeper into each of our patient’s history, goals, and lifestyle. We recognize that everyone is a unique individual and our bodies work differently. AAI takes this into account when we develop and organize your profile and pharmaceutical protocol. There is no one size fits all remedy. A thorough evaluation of your blood work will reveal areas of focus, signs of potential health concerns, as well as ailments you may be experiencing. Testosterone replacement therapy in conjunction with supplemental pharmaceuticals can drastically increase energy levels and reduce Chronic Fatigue. Testosterone Therapy has also been proven to improve mood, bone density, strengthen the immune system, reduce body fat, improve muscle mass, and reduce feelings of depression.

Like any use of medication, testosterone replacement therapy does not come without risks. Before injectable Testosterone replacement therapy is started, you must complete our Medical History Form, Blood Work, and Physical Examination in order to rule out any possible contradictions to Testosterone therapy. Blood Work is essential in determining your free testosterone levels. This process can be facilitated close to your home. At AAI, we feel it is imperative to continue to monitor hormone levels throughout the duration of your treatment. We have implemented various programs to help facilitate those follow up’s. You do not have to schedule an appointment to go to a lab to have blood drawn for these follow-ups. We provide you with a 7-day mouth swab kit. This provides our physician with data over a consecutive 7- day period of time for remarkable accuracy. It assures you are getting the most out of your therapy and that any required adjustments are made accordingly. This is essential to ensure that you are enjoying all the benefits that you wanted and deserve your testosterone therapy while avoiding any potential health risks.

**NOTE**  The content contained in this blog is subject to interpretation and is the opinion of the content writer.  We do not claim it to be fact.  We encourage you to consult a medical doctor before taking any prescribed medications or supplements.

At AAI Rejuvenation Clinic, we advise anyone to think seriously about beginning Hormone treatment if there is no medical need for it. However, we will take every precaution to ensure that you read all the positive benefits from your program by providing the latest at-home hormonal mouth-swab testing. This will ensure we are continually monitoring your progress and aware of any negative side effects. Fill out the Medical History Form or call us at (866) 224-5698

June 27, 2015 by Joseph Fermin 1 Comment

Hormone Can Improve Muscle Mass and Strength 5 (1)

The Right Hormone Can Improve Muscle Mass and Strength

Testosterone is essential in the production of strong and healthy muscles. Reduced muscle mass in men is often a result of declining levels of testosterone. Testosterone therapy, in combination with other hormones, is directly associated with the stimulation of protein synthesis in the body and the production of muscle tissue. The hormone binds to receptors in the muscle cells, telling muscles to contract and grow. If there is a deficiency of testosterone, the body suffers from muscle loss.

Testosterone Therapy Vs Testosterone Supplements

After the age of thirty, there is a slow but steady decline in testosterone levels. After forty, somewhere between 0.5- 1.0% of muscle mass is lost per year. These results are significantly worse in men suffering from low testosterone levels.

The increase in lean body mass, or muscle mass, through testosterone therapy, can be highly beneficial. Greater lean body mass helps raise metabolic rate. The higher the resting metabolic rate, the more calories burned while resting. Therefore, testosterone therapy can also assist in avoiding unwanted weight gain.

Testosterone injections and testosterone supplements produce a reasonable increase in lean body mass in men that are suffering from low testosterone levels. Patients undergoing testosterone replacement therapy can expect to gain between three to six pounds of lean muscle mass during the first six months of their program.

How to Gain Muscle/Lose Fat

Once we hit 30, it’s all downhill for the body. The lean body mass of our organs starts to shrivel, while the adipose mass, or fat mass, increases. Between the ages of 30 and 75, liver, kidneys, brain, and pancreas atrophy by 30% on average. In men between the ages of 40 and 80, The LBM declines about 5% per decade and in women by 2.5% per decade. Meanwhile, at the same time, the body fat in both sexes is expanding. By the late 30s, men are starting to gain fat in the gut. The upshot is that men between the ages of 30 and 70 don’t gain weight, but women’s mass shrinks by 30% and the fact expands by 50%. Women as they age mainly accumulate fat on their hips. But when women start to go through menopause, the belly rolls begin for them also.

These bodily changes are not just an affront to vanity, but a threat to health and longevity, according to gerontologist. First, the amount of aerobic power is directly connected to the amount of LBM. Second, this shrinkage of the vital organs means that they cannot do their jobs as well, whether it is the heart pumping, the muscles lifting, or the kidneys clearing metabolic wastes from the blood. Third, as the abdominal fat rises, so does the risk for heart attack, hypertension, and diabetes.

Here at AAI Rejuvenation Clinic, we’re ready to help. Our services are discrete and confidential. Contact us today at (866) 224-5698 or fill out our medical history form. Our trained wellness team is eager to get you started.

Testosterone Injections – Curious about testosterone injections Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698

**NOTE**  The content contained in this blog is subject to interpretation and is the opinion of the content writer.  We do not claim it to be fact.  We encourage you to consult a medical doctor before taking any prescribed medications or supplements.

At AAI Rejuvenation Clinic, we advise anyone to think seriously about beginning Hormone treatment if there is no medical need for it. However, we will take every precaution to ensure that you read all the positive benefits from your program by providing the latest at-home hormonal mouth-swab testing. This will ensure we are continually monitoring your progress and aware of any negative side effects. Fill out the Medical History Form or call us at (866) 224-5698