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May 31, 2018 by Joseph Fermin 0 Comments

Testosterone Therapy Vs Testosterone Supplements 0 (0)

Testosterone Therapy Vs Testosterone Supplements

Testosterone Therapy Vs Testosterone Supplements: Testosterone is stimulated and produced by the testes and is key to driving male sexual behavior. Although testosterone is a sex hormone, it plays many crucial roles in the body. It is responsible for regulating a man’s sex drive (libido), bone and muscle mass, fat distribution and the production of red blood cells, Decreased libido and sperm. The body begins to produce testosterone as early as seven weeks after conception, with levels reaching their peak at puberty. As men age, levels of testosterone start to drop, and this affects individuals in different ways.

Decreased Motivation: As testosterone production diminishes so do energy boosting components and restful sleep, thus producing decreased motivation.

Decreased libido: Low levels of testosterone cause a reduction in sex drive.

Depression: When a person experiences low testosterone levels it alters hormone production, which can lead to depression.

Erectile Dysfunction: Testosterone supplementation can be used to reverse or correct low testosterone-induced erectile dysfunction.

Fatigue: A decrease in testosterone levels leads to hormonal changes, which can cause fatigue. This can be exacerbated by low testosterone-induced sleep loss, which can easily turn into a vicious cycle.

High Cholesterol: High cholesterol is a silent killer that can lead to a variety of heart conditions. Testosterone injections, when used in a proper protocol, can lower cholesterol, blood pressure, and triglyceride levels.

Low Energy & Fatigue: Symptoms of aging can be a direct result of diminishing levels of testosterone or (Low-T) in the body. As we age, our bodies produce less and less testosterone, causing low energy and fatigue.

Memory Loss: Some recent evidence suggests that testosterone might help prevent and treat the effects of brain aging. Some patients treated with testosterone injections expressed a palpable increase in their cognitive function, short- and long-term memory, and vocabulary improvements.

Thyroid: The hormones produced by the thyroid and adrenal glands regulate key processes throughout the body. If thyroid hormone and cortisol levels are abnormal, the rest of the body does not function properly.

Weight Gain: The production of certain hormones decreases after the age of 30. The lean body mass of some organs also starts to decrease, whereas fat mass increases.

When Age Becomes The Deciding Factor

testosterone

After the age of 30, your body starts declining in hormones production, and the body decreases its testosterone production. This decrease, however, is very gradual and its effects can only felt around the age of 50. Common signs of testosterone decline include fatigue, decreased libido and problem having erections. While these effects can be most nerve-wracking, they are relatively common. Talk to your doctor at this stage, who will examine your condition and accordingly prescribe medicines or advise lifestyle changes.

The problem arose when these effects were seen, at or below the age of 40. Low levels of testosterone at a younger generation usually point to an underlying medical condition and warrant more in-depth investigation. It is essential that men consult a qualified doctor or men’s health specialist at the earliest, who will determine the underlying cause and how best to treat it. Some reasons for low testosterone production include underactive testes, undescended testicles, physical injury to the testicles, pituitary disorders or inherited conditions such as Klinefelter’s syndrome.

Know Your Treatment Options

Once a case of low testosterone is confirmed, patients have advised a mix of lifestyle changes (such as increased physical activity, healthy diet), counseling and medication are bioidentical 191 amino acid (orals or injectables). The choice of treatment made depending on the patient’s medical history, levels of testosterone, age and physical condition. Testosterone replacement therapy is another useful treatment option and helps restore the body’s declining testosterone levels. However, it must be taken under supervision since excessive testosterone is also harmful. If problems such as erectile dysfunction persist and hamper the patient’s relationship and quality of life, doctors may recommend other therapies to help restore erections.

Testosterone Boosting Supplements: Good Or Bad?

Boosting Supplements: Good Or Bad?

In the quest for ‘physical fitness’ and ‘bodybuilding’, a growing number of young men in their 20s and 30s try to boost their testosterone levels through external testosterone supplementation, Includes natural supplements, and or synthetic supplements (anabolic steroids). However, use of these supplements (test boosters and AAS) can have damaging and irreversible effects on the body in the long term, such as a reduction in sperm count (even zero counts!), excess fluid retention, enlargement of the prostate and an increase in red blood cells.

My advice to everyone reading this piece is this: Protect your sexual health. If you observe changes in your sexual response or experience any difficulty being intimate with your partner, talk to a qualified doctor at the earliest. If low testosterone is to blame, your doctor will discuss suitable treatment options and guide you in making an informed choice. Do not resort to testosterone supplementation on your own, as this may do you more harm than good in the long run.

Dr. Rupin Shah is a Urologist at the Lilavati Hospital in Mumbai and has been a part of the medical field for decades.

References:

1) NIH. Understanding How Testosterone Affects Men. Testosterone Therapy Vs Testosterone Supplements. Available at https://www.nih.gov/news-events/nih-research-matters/understanding-how-testosterone-affects-men

2) USRF. History of Testosterone Replacement Therapy (TRT). Testosterone Therapy Vs Testosterone Supplements. Available at https://www.usrf.org/news/TRT/history.html

3) Healthline Newsletter. The Effects of Testosterone on the Body. Testosterone Therapy Vs Testosterone Supplements. Available at https://www.healthline.com/health/low-testosterone/effects-on-body#1

4) American Urological Association. Testosterone for Erection Problems. Testosterone Therapy Vs Testosterone Supplements. Available at http://www.choosingwisely.org/patient-resources/testosterone-for-erection-problems/

January 30, 2018 by Joseph Fermin 0 Comments

Testosterone Therapy Improves Sexual Interest In Older Men 0 (0)

Testosterone Therapy Improves Sexual Interest in older men, and a controlled study to date finds testosterone can address low libido, erectile dysfunction

Testosterone Therapy Improves Sexual Interest In Older Men, the Older men with low libido and low testosterone levels showed more interest in sex and engaged in the more sexual activity when they underwent testosterone therapy, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

The study of Testosterone Therapy Improves Sexual Interestis the most significant placebo-trial in older men conducted. The sexual function study is part of the Testosterone Injections Trials, a series of seven studies examining the effectiveness of testosterone therapy in men who are 65 or older, who have low testosterone levels and are experiencing symptoms of low testosterone deficiency. The research is supported primarily by the National Institutes of Health.

Testosterone is an essential a male sex hormone help in maintaining Libido, sex drive, erectile function, and sperm production and much more. The Endocrine Society’s Clinical Practice Guideline recommends using testosterone therapy to treat men with symptoms of androgen deficiency and low testosterone levels.

In the past 50 years, use of injectable testosterone therapy has rapidly expanded among men population. Testosterone levels decline as men age, as early as 30 years old and some men develop low testosterone symptoms.

The placebo-controlled effect and double-blinded trial examined the effect of injectable testosterone therapy on sexual function in a group of 470 men. The men were in the study through 12 academic medical control centers. The participants were at least 65 years old and older, with low testosterone levels, based on the average results of multiple tests.

Testosterone Therapy Improves Sexual Interest, The men treated with injectable testosterone therapy displayed consistent improvement in libido and 10 of the 12 sexual activity measurements, nighttime erections, masturbation, and including frequency of intercourse. In comparison, with men who received the placebo testosterone did not change their responses over the year-long medical study done.

testosterone-injections

 

Testosterone Injections is the most common treatment for men going through andropause. This therapy may provide help and relief from the symptoms and help improve the quality of life in many cases, also lifestyle changes such as increased exercise, stress reduction, and proper nutrition also help.

Testosterone therapy is available in different forms, ask your doctor he will help determine which treatment is best for you.

TESTOSTERONE INJECTIONS: This treatment involves doses of bioidentical (Testosterone Cypionate, Testosterone Enanthate, and Testosterone Propionate).

TESTOSTERONE PATCHES: People who wear a piece containing testosterone receive the hormone through the skin. The patches allow a slow, steady release of testosterone into the bloodstream.

TESTOSTERONE GEL: This treatment is also applied directly to the skin, usually on the arms. Because the gel may transfer to other individuals through skin contact, a person must take care to wash the gel from the hands after each application.

TESTOSTERONE CAPSULES: This is yet another option for testosterone replacement. Men with liver disease, poor liver function, severe heart or kidney disease, or too much calcium in their blood should avoid testosterone capsules.

Follow-up visits with your doctor will be necessary after the initial treatment begins. At follow-up visits, your doctor will check your response to the treatment and make adjustments, if necessary.

November 13, 2017 by Joseph Fermin 0 Comments

An Inside Look at Testosterone Injections Therapy 0 (0)

Inside Look Testosterone Injections Therapy

testosterone injections therapyTESTOSTERONE INJECTIONS THERAPY

Testosterone is an essential factor in males, that does more for men than just promote sex drive. Low Testosterone levels decline as a part of healthy aging and are the cause of several physiological changes. Low Testosterone level symptoms include;

1) Reduced Motivation
2) Erectile Dysfunction
3) Loss of Libido or sex drive
4) Fatigue and low energy
5) Increased Cholesterol Levels
6) Memory and Concentration
7) Decreased Muscle Mass
8) Thyroid Dysfunction and more

Since these symptoms are common in low testosterone, physicians will often include hormone levels as part of routine blood work. Normal levels of testosterone are between 300 and 1,000 ng/dL. If a blood test shows that your levels are far below the norm, your doctor may suggest testosterone injections. The treatment is called TRT.

SYMPTOMS OF LOW TESTOSTERONE

Most men naturally start losing testosterone when they hit their 30’s. (low T). Common symptoms of low Testosterone include:

1) Erectile dysfunction (ED)
2) Changes in sex drive
3) Decreased sperm count
4) Depression or anxiety
5) Weight gain
6) Hot flashes

TESTOSTERONE AND DIAGNOSIS

Many men may want to diagnose themselves with a testosterone kit. The problem with self-diagnosis is that many of the symptoms of low Testosterone are healthy parts of aging. So using it for diagnosis isn’t reliable. Our doctor may order testosterone blood test. It is the only way to find out if you have low testosterone.

To get a perfect reading our doctor will take a look at your health history, physical exam and blood test to measure your testosterone levels. You’ll also likely have a test that measures your red blood cell count.

POTENTIAL BENEFITS OF TESTOSTERONE INJECTIONS THERAPY 

The purpose of Testosterone Injections Therapy is to help regulate hormone levels and to help address problems related to low Testosterone. For men with low Testosterone, the benefits of these injections can include:

1)  Motivation and Memory Loss
2)  Sex Drive & Desire
3)  Depression and Energy
4)  Cholesterol and Osteoporosis
5)  Erectile Dysfunction
6)  Muscle Mass and Better Sleep
7)  Wounds healing & Illness
8)  Thyroid Dysfunction and more

TESTOSTERONE CAN HELP WITH FAT AND MUSCLE CHANGES

Men have less body fat than women; This is partly related to testosterone, which regulates the fat in the body and muscle maintenance in your body. You’ll likely also notice an increase in body fat, especially around your midsection.

Your hormones also help regulate muscle growth. So, with low Testosterone, you may feel like you’re losing muscle size or strength.

Testosterone shots regulate fat distribution, but you shouldn’t expect significant weight loss changes from hormone therapy alone, without exercise. As for maintenance of muscle, testosterone therapy has been found to improve increase muscle mass, but not strength.

TESTOSTERONE INJECTIONS THERAPY AND SPERM COUNT

Low sperm count in men is a common side effect of low Testosterone. This problem can make it difficult to get your partner pregnant.

TESTOSTERONE INJECTIONS THERAPY AND THE BOTTOM LINE

Testosterone injections therapy can only be helpful If you just have low Testosterone. If you’re wondering if testosterone is a right choice for you, ask your doctor. They can test you for low Testosterone. Ask your doctors, or Give us a call, if testosterone injections therapy would be a good choice for you.

If you don’t end up having low Testosterone but still feel like your hormone levels might be off, keep in mind that proper Food, Regular exercise, could help you increase testosterone naturally and make you feel better. If that doesn’t help, be sure you contact us for help.

August 25, 2016 by admin 3 Comments

Anavar: The Good, The Bad and The Ugly 0 (0)

Pros and Cons of Anavar

Anavar has been around since 1964. It was bought out by Pfizer in 2003. Since then, it has seen a popular reemergence and has been termed the “safest” steroid available. Unfortunately, this is dangerous and brings confusion to the masses whom misleadingly supplement with this compound.

Anavar

We have been receiving many requests for Anavar from patients that have shopped around with other local clinics. Sadly, clinics that, despite the consequential ramifications, opt to sell this controlled substance to their patients. Moreover, they do it under the guise of providing medical treatment, when in fact, this is one of the reasons it was once illegal: there is no real medicinal purpose for Anavar.

  • Anavar is an anabolic steroid.
  • Anavar is not a bio-identical hormone, as is testosterone.
  • Anavar has very little androgenic (testosterone Injections) properties. This is the reason it does not aromatize. Only androgens aromatize.
  • Initially, Anavar was produced to assist patients with lipodystrophy (excessive muscle loss, usually as a result of AIDS).

The Good, The Bad, and The Ugly.
First the Good

  • Because there is no conversion to estrogen with Anavar, blockers nor inhibitors are needed for its use. Estrogen conversion manifest most of the visible side effects men fear from a testosterone therapy program: mood swings, libido loss, water retention, weight gain, etc.
  • Anavar increases anabolism significantly. This allows the muscle to absorb a lot more protein. Being in anabolic state intensifies the muscle building process. Strong, dense muscles develop and are longer lasting than when developed on other steroids.
  • Because Anavar has almost no androgenic properties, it does not cause a swift shutdown of HPTA (the process that invites endogenous low testosterone production)
  • Muscles developed with the aid of Anavar administration are sharper and more cut.
  • Studies have shown Anavar to diminish visceral (stomach area) fat with only moderate exercise. Most impressively, even after discontinuing usage, the subjects kept off the fat. Of course, they were still exercising and minding their caloric intake.
  • Anavar can lubricate joints and assist with joint related pain.

The Bad

  • Want to know the truth behind why Anavar is considered the “safest” or “most mild” anabolic steroid available? In its pharmaceutical form, Anavar comes in 2.5 mg tablets. At that therapeutic dose, even a child could take it without systemic repercussions. There is basically no negative impact on the liver, even if taken on a daily basis.
  • To build significant muscle on Anavar alone, at least 50 mg a day would be needed. At these quantities, arduous taxing of the liver is intense and inevitable.
  • Anavar is a seventeen alpha alkylated. This means it is structured to prevent a breakdown in the liver. This makes the effects of the drug much greater but puts an unimaginably damaging strain on the liver.
  • The required dosage for effective muscle “building” is what makes legitimate medical claims of Anavar’s “mildness” a myth.
  • In a nutshell: With Anavar, what makes it safe, makes it not very effective, and once it becomes effective, it is not very safe.

The Ugly

  • 2.5 mg is the pharmaceutical dosage this brand medication comes in. Patients should be wary of 20 mg to 50 mg tablets. Those are only made through UG laboratories. Patients should require their medication come labeled with their name, the prescribing physician’s name and the providing Laboratories information, including DEA number. This info should be followed up with some quick research on the involved laboratory.
  • Unless you are suffering from acute muscle wasting, there is no medicinal purpose for taking Anavar.
  • Anavar is actually pretty amazing stuff “if you are a bodybuilder willing to administer illegal substances.” It does have the ability to increase strength significantly in a short period of time. However, at the dosages required for effective muscle building, the liver finds itself under constant attack. This program can only be used as a kick-start program.
  • Patients prescribed Anavar under the guise of it being a health supplement should consider very carefully the integrity of the organization they are working with.
  • A “real” Anavar program should not surpass 4 to 6 weeks. Anything beyond that, especially at dosages beyond the 20mg mark, will have impacting effects on the liver.
Real Testosterone Therapy

anavarIn conclusion, Anavar, if abused, is actually the real deal. It then works well to strengthen muscles and build rigid, strong tissue. It might even assist with the loss of stubborn belly fat. Unfortunately, 1) the dosage needed makes it unimaginably toxic to the liver and 2) there is no actual medical use for it and cannot be taken for very long at all. For this reason, unless you are a bodybuilder willing to trade in your future health for accelerated, temporary gains now, Anavar should never be on your radar.

If you are looking for a supplement to take to maximize your masculine efficiency while ensuring a health-enjoying, long, quality life in the future, consider learning more about a bio-identical Testosterone replacement protocol.

Again, if you are considering bettering your health, changing your physique, improving your sex life and libido, consider a bio-identical testosterone replacement program. We can provide you the same type of testosterone your body produces. Of course, there is still the potential for side effects but, because it is bio-identical, your body is more receptive to it and you can continue therapy safely for many years. Most importantly, our doctors are experts in the art of Testosterone replacement therapy. We make sure our patients have all the required counterparts to their therapy to ensure better keeping unwanted side effects out of the picture.

A properly administered testosterone injection program can reignite the fire you have lost. It may sound intense, but the results of revitalizing the male body are unparalleled and near impossible to denote. It is simply a reawakening of life; a happier, more efficient life.

Testosterone Therapy Information

August 24, 2016 by admin 0 Comments

Why AAI Rejuvenation Clinic? 0 (0)

Why AAI Rejuvenation Clinic?

AAI Rejuvenation Clinic is breaking the mold. In a very short period, we have brought our ranking position to be noted as one of the best hormone health centers in existence. A quick Google search for “best hormone clinic in the country” yields first page results containing AAI Clinics as one of the first brick and mortar locations available for selection.

What is Actually Done at AAI Clinics?

AAI Rejuvenation Clinic is a hormone clinic. No, hormones are not only for athletes or the elderly. That is a huge misconception keeping millions of people away from enjoying their happiest and healthiest life possible.

  • We only age because our hormone levels recede.
  • By the age of 27, we all begin the aging process.
  • Replacing your hormones to maintain healthy levels, similar to the levels you had during youth, helps the body operate more efficiently and remain younger, longer.
  • If you are a bit older and return your hormones to healthy levels, tissue throughout the body essentially strengthens and rejuvenates.
  • The body positively responds to the higher, healthier hormone levels.

What’s Different at AAI?

Patients do not only receive hormones – You cannot help heal 1 million different people’s health problems with a group of only 15 basic medications and hormones. Other compounds are necessary and vary from person to person. We supply these.

Therapy-supporting nutraceuticals – Depending on patient goals and individual ailments, targeted supplements are also prescribed to maximize results and the efficiency of therapy. We practice focused healing and goal achieving.

Most competitive pricing in the industry – From inception, we have known this industry is saturated with overpriced margins. We knew providing exceptional patient care in conjunction with the best available pricing was an impermeable recipe for everybody’s success.

Healing from the core – Foods are medicine. We provide information on symptom-focused healing foods, including viable recipes and food “per item” nutritional details and medicinal property explanations. Eating the right foods to heal your body and reach your goals is one of the biggest kept secrets, yet fastest ways to obtain lasting results.

Hassle free – 

1. Patients only need three simple documents for qualification.
2. Patients never need to leave their city.
3. Individualized assistance via assigned medical professional 7 days a week from 9 AM to 10 PM EST.
4. Prescription fills delivered to home or office in discrete packaging.
5. Prescribing Physician’s online or phone consults available.
6. For our busy patients, a physician’s visit to their home or office can be organized.

Promotions at AAI Rejuvenation Clinic

  • Physician’s consult and Initial qualifying blood work are now an all-inclusive, one-time fee. Instead of charging patients individually for blood work as well as the required doctor’s consult, we now offer a one-time transaction that saves patients about 30% overall.
  • Are you interested in testosterone therapy, sermorelin therapy or hGH therapy? Let us give you facts.
  • You can be on your way to feeling younger, better and healthier in less than 4 days.
  • Fill out our short form and be contacted within 24 business hours.

 

Symptoms Therapy Information

June 27, 2016 by admin 1 Comment

Testosterone Effects on Prostate 0 (0)

Testosterone Effects on Prostate Health.
How That’s Changing.

Testosterone effects on prostate levels and its functionality have always been a delicate topic of conversation. There is a lot of controversy surrounding the different theories on its impact. We have all heard the stories and read the articles where Testosterone injections, or, really any form of testosterone therapy, are allegedly attributed to malignant side effects in the participants. What is most interesting is the notion there actually have not been many studies done focused on that particular reaction to therapy. By this we mean, double-blind, placebo-controlled studies as is the standard of our trusted Food and Drug administration’s qualification process.

  • testosterone effects on prostateWe do not want to give off the impression we share this recently accepted hypothesis, which suggests testosterone effects on prostate health do not necessarily have a correlation. However, it is important to shed light on the fact the medical community and its core beliefs and socially accepted diagnoses often shift, and dramatically. Also, as the world awakens, begins to ask more questions and not accepting the typical status quo, we’ve all become a bit more enlightened to the ways of the world. We’ve learned that big pharma and its main directors don’t necessarily have our health or us at the forefront of their decision-making. Many times profits interfere with factual descriptions and publicly distributed medicinal allocations. We must use discernment when we read data and, dig deeper if it’s a matter of personal importance. Everyone who searches finds…

Particularly men on testosterone therapy, they should do their best research to help them better understand the involved variables. Better understanding of testosterone effects on prostate health can help patients make the best determination, based on their personal considering factors.

A recent study led by researchers at NYU Langone Medical Center denoted men prescribed a minimum of 1 year of testosterone injections replacement therapy demonstrated no additional risk for prostate cancer. One researcher, in particular, Stacy Loeb,testosterone effects on prostate MD, MSc, who happens to be a urologist at NYU Langone Medical Center shared a different notion. She suggests physicians should continue to evaluate prostate cancer risk factors and better understand functionality and future health— such as age over 40, family history of the disease and black ancestry — among men prescribed testosterone therapy. Dr. Loeb said in a corresponding press release, “they should not hesitate to prescribe [testosterone therapy] to appropriate patients for fear of increasing prostate cancer risk.”

In their research to better understand testosterone injections effects on prostate health, Dr. Loeb and her contemporaries collected data from close to 25 million medical files on a group of men. These men were enumerated in the National Prostate Cancer Register and Prescribed Drug Register in Sweden.

  • testosterone effects on prostateThey were able to classify 38,570 men diagnosed with prostate cancer between 2009 and 2012. Of these men, 284 received testosterone therapy treatments prior to their prostate tissue diagnosis. These numbers were then compared to the results of 192,838 men who showed no development of cancer in the prostate. Most interestingly, 1,378 of those men had been on testosterone therapy.
  • Multivariable examination helped conclude no significant association between any kind of testosterone injections replacement therapy and prostate cancer risk (OR = 1.03; 95% CI, 0.9-1.17). In fact, the results suggested a 35% increase in low-risk prostate cancer occurrence after the commencement of a testosterone therapy regimen (OR = 1.35; 95% CI, 1.16-1.56). Results also showed a lower risk of aggressive disease among men who used testosterone injections replacement therapy for more than a year (OR = 0.5; 95% CI, 0.37-0.67).

testosterone effects on prostateFrom this analysis, the demarcations indicating the lessened potential for testosterone injections therapy to have a negative side effect on the prostate are significantly prominent. Testosterone injections effects on prostate health and blood testing levels shown to have little to no association. That being said, until the concrete information has changed the national standard on this widespread opinion, AAI Rejuvenation Clinic will continue to supplement each one of our therapies with the necessary medicinal requirements currently utilized to maintain possible, unwanted side effects from interfering with a successful testosterone therapy treatment. If you have any questions or comments related to this subject, please fill out our short contact form and someone will reach you within 24 hours. Make sure to leave your phone number. You can also call us directly by dialing:

Testosterone Therapy Information

February 5, 2016 by admin 0 Comments

Testosterone Therapy and Prostate Cancer 0 (0)

Prostate Cancer
Testosterone therapy and Prostate Health, Testosterone Therapy and Prostate Cancer

Main article details obtained from the US National Library of Medicine 


Testosterone Therapy and Prostate Cancer

Prostate Cancer and Testosterone Therapy and Prostate cancer is a considerably well-known paradox, right? Did you know that there is actually a lack of evidence for testosterone therapy causing prostate cancer? We have actually presented doctors and interested people at seminars an alternative view to the misdirection that Harvard’s Chief of Urology made in the 1930’s. Mistakes so egregious that they are still quoted as fact unto this very day. The most outlandish mistake acknowledged a few years ago by Harvard Medical Review Board was the error in the 1930’s research concluding that testosterone caused prostate cancer.

  • The peer-reviewed article in a leading Urological Journal below explains in great detail that the modern research into this issue shows, once again, no relationship at all between an increase in prostate cancers and even PSI’s and testosterone replacement therapy.

This Peer Reviewed scientific Article was written by Dr. Michael K Brawer M.D., one of the foremost Research Urologists in the USA. He has written over 200 articles, 25 books and 74 government funded grants to study testosterone’s effect on the prostate.

What does this mean for our presentation of this issue at AAI Rejuvenation Clinic? We think it’s definitely a promising twist that deserves to be presented to interested clients and patients, explaining that:

  • More recent advances in urological research show no connection between testosterone and an increased risk of prostate cancer.
  • There is only one peer-reviewed study in patients with advanced prostate cancer, that testosterone was shown to have any deleterious effect on a prostate which already had advanced cancer.
  • This is the route taken by Dr. Janine Cabanellas M.D. a Harvard-trained Dr. who now owns the Wellington Institute of wellness and Anti-Aging.

We at AAI Clinics want to express that our interest is to stay on top of the latest and most up-to-date medical advances and research. We also aim to continually educate our clients and patients with these informational pieces as they surface, even if only in the form of an intellectual discussion, such as this one. A meeting of the minds, if you will.

Retrospectively, despite the more recent studies pointing to the fact that the connection between testosterone therapy and prostate cancer may be a high-profile medical misconception, until the general, medical consensus has agreed and changed in their direction of treatment, the physicians here at AAI center their patient’s therapies with all the precautionary necessities and medications.

  • In fact, we are one of the only clinics that have a designated section for accompanying nutraceuticals significant to the patient’s therapy and focused on minimizing any possible side effects.
  • Our nutraceuticals come exclusively from Douglas Labs.
  • Do your own research. Everyone says they are the best. Douglas labs have the documentation and FDA seals of approval to back the claims.

One of the best nutraceuticals to take while on testosterone therapy (or even if you are not on testosterone therapy) to focus on the health of the prostate is TestoQuench for men. Definitely, check it out. Call us up for $10 off per medication during the next 10 days:

The effect of hormonal regulation of prostatic tissue growth and function, particularly reflected by serum PSA level, is, of course, a well-studied area. Particular attention has been paid to the effect of androgen withdrawal as a treatment of prostatic carcinoma.

  • Several investigations have attempted to correlate serum PSA levels with testosterone levels.
  • Two studies, those of Behre and associates and Svetec demonstrated statistically significantly lower levels of PSA in hypogonadal men than normal men.
  • Four other investigations revealed a trend toward lower levels of PSA in hypogonadal men, although this trend did not achieve statistical significance in any of the studies.

Several investigators have measured PSA levels before and after testosterone replacement.

  • In six reports PSA was found to increase significantly after testosterone replacement.
  • In others, although there was a tendency for PSA to increase, this trend did not reach statistical significance.
  • In only one study investigating this phenomenon, that of Snyder et al, did the PSA level remain unchanged?
  • Three investigators simply looked at the chance of PSA increasing to above the threshold of normal (4.0 ng/mL). In none of these studies did this increase occur.
  • A number of animal models have demonstrated that exogenous androgens stimulate established prostate cancer in a dose-dependent fashion. Testosterone given to patients with advanced metastatic prostate cancer results in severe pain at bony metastatic sites.
  • There have been three investigations in which supplemental testosterone was given to eugonadal men. Indications were obesity with low normal testosterone, in healthy volunteers, and in men in a long-term contraception trial. In none of these investigations on eugonadal men was an increase in PSA observed.
  • Again, due to the lack of agreement in the study results, no relationship between serum testosterone and PSA was established.

Cancer Risk and Patient Monitoring

Despite the conclusion that it is highly doubtful that the administration of testosterone therapy produces any promotional effect in the absence of an already existing cancer, the patient needs to be monitored. A standard urologic evaluation to rule out malignancy should be undertaken prior to initiating androgen supplementation. Recommendations include a carefully performed digital rectal examination (DRE) along with serum PSA measurements. If either the rectal examination is abnormal or the PSA level exceeds 4.0 ng/mL, ultrasound-guided prostate biopsy becomes mandatory. If the initial PSA levels are within normal limits and the DRE is negative, one should feel comfortable initiating androgen supplementation in properly identified patients. It is imperative that the patient is carefully monitored for any changes in these prostate risk findings and we would recommend reassessment at 3 months. At that time, if the PSA level exceeds 4.0 ng/mL, or there is a change in DRE, the prostate biopsy is warranted. We recommend an additional prostate assessment in 3 more months (6 months after initiating therapy) and at least annually thereafter.

Conclusion

The effectiveness of testosterone therapy in ameliorating the signs and symptoms of hypogonadism in the aging male will lead to increased implementation of this therapy. There have been multiple attempts to correlate the administration of testosterone to prostate carcinogenesis, but the studies have failed to produce consistent results. Similarly, the studies which attempt to correlate increased testosterone with increased PSA levels have been unconvincing. Nor have the studies been able to link DHT, the more active metabolite of testosterone, to the development of carcinoma. The prevailing opinion is that restoring your low testosterone levels to physiologic levels offers no increased risk of carcinoma. However, there is little doubt that the studies show a deleterious effect on existing clinical carcinoma of the prostate. With the elimination of the presence of an existing carcinoma of the prostate, through physical examination and laboratory studies, before initiation of testosterone therapy, and the continuous monitoring of the patient throughout therapy, testosterone injections therapy will prove safe with regard to prostate health.

~ The great majority of this content came from the US National Library of Medicine ~

Testosterone Therapy Information

What Is Testosterone?

Testosterone Therapy Info

Testosterone Injections

symptoms of Low Testosterone

causes of Low Testosterone

Low Testosterone in Men

Low Testosterone in Women

Low Testosterone

Testosterone Cypionate

Testosterone Propionate

Testosterone Enanthate

Testosterone Patches

Testosterone Gels

Testosterone Boosters

Side Effects of Testosterone

February 4, 2016 by admin 0 Comments

Testosterone Cypionate Description 0 (0)

Testosterone Cypionate description injections

Testosterone Cypionate Description injection for intramuscular injection contains Testosterone Cypionate which is the oil-soluble 17 (beta)- cyclopentyl propionate ester of the androgenic hormone testosterone. Testosterone Cypionate is a white or creamy white crystalline powder, odorless or nearly so and stable in air. It is insoluble in water, freely soluble in alcohol, chloroform, dioxane, ether, and soluble in vegetable oils. The chemical name for Testosterone Cypionate is androst-4-en-3-one,17-(3-cyclopentyl-1-oxopropoxy)-, (17β)-. Its molecular formula is C27H40O3, and the molecular weight 412.61.

The structural formula is represented below:

Testosterone Cypionate injection, USP is available in two strengths, 100 mg/mL and 200 mg/mL Testosterone Cypionate, USP.

Each mL of the 100 mg/mL solution contains:

Testosterone Cypionate……………………………………………………………………. 100 mg
Benzyl benzoate ……………………………………………………………………………… 0.1 mL
Cottonseed oil ………………………………………………………………………………… 736 mg
Benzyl alcohol (as preservative)………………………………………………………… 9.45 mg

Each mL of the 200 mg/mL solution contains:

Testosterone Cypionate……………………………………………………………………. 200 mg
Benzyl benzoate………………………………………………………………………………. 0.2 mL
Cottonseed oil………………………………………………………………………………… 560 mg

Benzyl alcohol (as preservative)………………………………………………………… 9.45 mg

Testosterone Cypionate – Clinical Pharmacology

Endogenous androgens are responsible for normal growth and development of the male sex organs and for maintenance of secondary sex characteristics. These effects include growth and maturation of the prostate, seminal vesicles, penis, and scrotum; development of male hair distribution, such as beard, pubic, chest, and axillary hair; laryngeal enlargement, vocal cord thickening, and alterations in body musculature and fat distribution. Drugs in this class also cause retention of nitrogen, sodium, potassium, and phosphorous, and decreased urinary excretion of calcium. Androgens have been reported to increase protein anabolism and decrease protein catabolism. Nitrogen balance is improved only when there is sufficient intake of calories and protein.

Androgens are responsible for the growth spurt of adolescence and for eventual termination of linear growth, brought about by fusion of the epiphyseal growth centers. In children, exogenous androgens accelerate linear growth rates but may cause a disproportionate advancement in bone maturation. Use over long periods may result in fusion of the epiphyseal growth centers and termination of the growth process. Androgens have been reported to stimulate the production of red blood cells by enhancing production of erythropoietic stimulation factor.

During exogenous administration of androgens, endogenous testosterone release is inhibited through feedback inhibition of pituitary luteinizing hormone (LH). At large doses of exogenous androgens, spermatogenesis may also be suppressed through feedback inhibition of pituitary follicle stimulating hormone (FSH).

There is a lack of substantial evidence that androgens are effective in fractures, surgery, convalescence, and functional uterine bleeding.

Pharmacokinetics

Testosterone esters are less polar than free testosterone. Testosterone esters in oil injected intramuscularly are absorbed slowly from the lipid phase; thus, Testosterone Cypionate can be given at intervals of two to four weeks.

Testosterone in plasma is 98 percent bound to a specific testosterone-estradiol binding globulin, and about 2 percent is free. Generally, the amount of this sex-hormone binding globulin in the plasma will determine the distribution of testosterone between free and bound forms, and the free testosterone concentration will determine its half-life.

About 90 percent of a dose of testosterone injections is excreted in the urine as glucuronic and sulfuric acid conjugates of testosterone and its metabolites; about 6 percent of a dose is excreted in the feces, mostly in the unconjugated form. Inactivation of testosterone occurs primarily in the liver. Testosterone therapy is metabolized to various 17-keto steroids through two different pathways.

The half-life of Testosterone Cypionate, when injected intramuscularly, is approximately eight days.

In many tissues, the activity of testosterone therapy appears to depend on reduction to dihydrotestosterone, which binds to cytosol receptor proteins. The steroid-receptor complex is transported to the nucleus where it initiates transcription events and cellular changes related to androgen action.

Indications and Usage for Testosterone Cypionate description

Testosterone Cypionate description injection is indicated for replacement therapy in the male in conditions associated with symptoms of deficiency or absence of endogenous testosterone.

  • Primary hypogonadism (congenital or acquired)-testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome; or orchidectomy.
  • Hypogonadotropic hypogonadism (congenital or acquired): gonadotropin or LHRH deficiency, or pituitary-hypothalamic injury from tumors, trauma, or radiation.

Safety and efficacy of Testosterone Cypionate description in men with “age-related hypogonadism” (also referred to as “late-onset hypogonadism”) have not been established.

Contraindications

  1. Known hypersensitivity to the drug
  2. Males with carcinoma of the breast
  3. Males with known or suspected carcinoma of the prostate gland
  4. Women who are or who may become pregnant
  5. Patients with serious cardiac, hepatic or renal disease

Warnings

Hypercalcemia may occur in immobilized patients. If this occurs, the drug should be discontinued.

Prolonged use of high doses of androgens (principally the 17-α alkyl-androgens) has been associated with the development of hepatic adenomas, hepatocellular carcinoma, and peliosis hepatis —all potentially life-threatening complications.

Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking.

There have been postmarketing reports of venous thromboembolic events, including deep vein thrombosis (DVT) and pulmonary embolism (PE), in patients using testosterone products, such as Testosterone Cypionate description. Evaluate patients who report symptoms of pain, edema, warmth, and erythema in the lower extremity for DVT and those who present with acute shortness of breath for PE. If a venous thromboembolic event is suspected, discontinue treatment with Testosterone Cypionate description and initiate appropriate workup and management.

Long term clinical safety trials have not been conducted to assess the cardiovascular outcomes of testosterone replacement therapy in men. To date, epidemiologic studies and randomized controlled trials have been inconclusive for determining the risk of major adverse cardiovascular events (MACE), such as non-fatal myocardial infarction, non-fatal stroke, and cardiovascular death, with the use of testosterone compared to non-use. Some studies, but not all, have reported an increased risk of MACE in association with the use of testosterone replacement therapy in men. Patients should be informed of this possible risk when deciding whether to use or to continue to use Testosterone Cypionate description.

Edema, with or without congestive heart failure, may be a serious complication in patients with preexisting cardiac, renal or hepatic disease.

Gynecomastia may develop and occasionally persists in patients being treated for hypogonadism.

The preservative benzyl alcohol has been associated with serious adverse events, including the “gasping syndrome”, and death in pediatric patients. Although normal therapeutic doses of this product ordinarily deliver amounts of benzyl alcohol that are substantially lower than those reported in association with the “gasping syndrome”, the minimum amount of benzyl alcohol at which toxicity may occur is not known. The risk of benzyl alcohol toxicity depends on the quantity administered and the hepatic capacity to detoxify the chemical. Premature and low-birth weight infants may be more likely to develop toxicity.

Androgen therapy should be used cautiously in healthy males with delayed puberty. The effect on bone maturation should be monitored by assessing the bone age of the wrist and hand every 6 months. In children, androgen treatment may accelerate bone maturation without producing a compensatory gain in linear growth. This adverse effect may result in compromised adult stature. The younger the child the greater the risk of compromising final mature height.

This drug has not been shown to be safe and effective for the enhancement of athletic performance. Because of the potential risk of serious adverse health effects, this drug should not be used for such purpose.

Precautions

General

Patients with benign prostatic hypertrophy may develop acute urethral obstruction. Priapism or excessive sexual stimulation may develop. Oligospermia may occur after prolonged administration or excessive dosage. If any of these effects appear, the androgen should be stopped and if restarted, a lower dosage should be utilized.

Testosterone Cypionate description should not be used interchangeably with testosterone propionate description because of differences in duration of action.

Testosterone Cypionate description is not for intravenous use.

Information for Patients

Patients should be instructed to report any of the following: nausea, vomiting, changes in skin color, ankle swelling, too frequent or persistent erections of the penis.

Laboratory Tests

Hemoglobin and hematocrit levels (to detect polycythemia) should be checked periodically in patients receiving long-term androgen administration.

Serum cholesterol may increase during androgen therapy.

Drug Interactions

Androgens may increase sensitivity to oral anticoagulants. The dosage of the anticoagulant may require a reduction in order to maintain satisfactory therapeutic hypoprothrombinemia.

Concurrent administration of oxyphenbutazone and androgens may result in elevated serum levels of oxyphenbutazone.

In diabetic patients, the metabolic effects of androgens may decrease blood glucose and, therefore, insulin requirements.

Drug/Laboratory Test Interferences

Androgens may decrease levels of thyroxine-binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction.

Carcinogenesis

Animal data

Testosterone has been tested by subcutaneous injection and implantation in mice and rats. The implant induced cervical-uterine tumors in mice, which metastasized in some cases. There is suggestive evidence that injection of testosterone into some strains of female mice increases their susceptibility to hepatoma. Testosterone is also known to increase the number of tumors and decrease the degree of differentiation of chemically induced carcinomas of the liver in rats.

Human data

There are rare reports of hepatocellular carcinoma in patients receiving long-term therapy with androgens in high doses. Withdrawal of the drugs did not lead to regression of the tumors in all cases.

Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking.

Pregnancy

Teratogenic Effects

Pregnancy Category X. (See CONTRAINDICATIONS)

Benzyl alcohol can cross the placenta. See WARNINGS.

Nursing Mothers

Testosterone Cypionate description is not recommended for use in nursing mothers.

Pediatric Use

Safety and effectiveness in pediatric patients below the age of 12 years have not been established.

Adverse Reactions

The following adverse reactions in the male have occurred with some androgens:

Endocrine and urogenital: Gynecomastia and excessive frequency and duration of penile erections. Oligospermia may occur at high dosages.

Skin and Appendages: Hirsutism, male pattern of baldness, seborrhea, and acne.

Cardiovascular Disorders – myocardial infarction, stroke

Fluid and electrolyte disturbances: Retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates.

Gastrointestinal: Nausea, cholestatic jaundice, alterations in liver function tests, rarely hepatocellular neoplasms and peliosis hepatis (see WARNINGS).

Hematologic: Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy, and polycythemia.

Nervous system: Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia.

Allergic: Hypersensitivity, including skin manifestations and anaphylactoid reactions.

Vascular Disorders: venous thromboembolism

Miscellaneous: Inflammation and pain at the site of intramuscular testosterone injection.

Testosterone Therapy Information

January 6, 2016 by admin 0 Comments

What is Testosterone-Cypionate? 0 (0)

Testosterone-Cypionate the form of testosterone provided most often in testosterone therapy. It’s a specific form of testosterone, slightly different than what human bodies produce on their own, but for reasons essential to its administration to the body. To maximize the benefits of male hormone therapy, testosterone Cypionate is one of the types of testosterone a person can inject or get in a gel. There are very specific reasons why this form of testosterone is most popular for therapy.

Testosterone is the substance produced in human bodies that regulate the expression of male characteristics. It also promotes healing and mental well-being. It’s a relatively small organic molecule that isn’t a protein or peptide-like HGH, but instead is very similar to cholesterol or Vitamin E; it’s a hydrocarbon ring, an oil-soluble type of substance. It travels to all parts of the body through the blood. In males, it’s produced by specific cells in the testicles, triggered by signals from the brain, which also travel through the blood. The amount of testosterone in a man’s blood correlates directly with the masculine traits he exhibits, i.e., being hairy, being strong, and having physical and mental energy.

The human body produces a natural form of testosterone.

When humans produce testosterone in their body, the specific type of testosterone that’s produced is just plain testosterone. No additional fragment is stuck to it, as in the case of testosterone-Cypionate where what’s called a Cypionate moiety is stuck to one end of the testosterone molecule.  Technically, human bodies don’t produce the Cypionate form, but doses of testosterone injections are taken in the Cypionate form as opposed to just plain testosterone by itself.

what is testosterone cypionate used if the body doesn’t make that form?

When testosterone-Cypionate is administered in the form of a gel or injection, the body converts the Cypionate form into plain testosterone. There are enzymes called esterases that target the connection between the Cypionate moiety and the testosterone molecule, breaking off the Cypionate from testosterone, leaving plain testosterone in the form that the body uses it. These esterases yield the same molecule of testosterone the body produces. This is why testosterone-Cypionate is referred to as bio-identical testosterone, putting it into the body is essentially equivalent to increasing what the body has made at one time and is already capable of using, natural testosterone in the form the body uses it.

A time-release effect provides stable hormone levels.

The reason the Cypionate form is administered, as opposed to just plain testosterone, is to provide a time-release type of effect. Making the molecule more oil-soluble tends to stabilize the blood levels of free testosterone, releasing more gradually over time. If free testosterone were injected directly, we’d observe a peak in its blood concentration immediately after injection followed by a rapid decrease thereafter. By injecting the Cypionate form, more of the testosterone gets absorbed by the body’s fatty tissue to be released more gradually over time. It gets dissolved into the blood more slowly, and the blood concentrations of testosterone Therapy resemble a more stable pattern useful for therapy. Instead of having to get multiple injections daily, with testosterone-Cypionate you can instead space out injections on the order of weeks.

As we discussed in our previous blog post about the different forms of testosterone, testosterone-Cypionate is only one out of several that are included in therapeutic doses. The dosage and forms that are prescribed to anti-aging patients differ from patient to patient. Whatever form is prescribed, it’s important to follow dosage instructions as precisely as possible. Both the form and the dosage times are chosen together to provide the most stable, consistent hormone levels possible, getting the most benefits with the least side effects.

 

 

November 27, 2015 by Joseph Fermin 0 Comments

What are the Prostate Problems with Testosterone 0 (0)

Prostate Problems and Testosterone Therapy

You can’t read anything about testosterone therapy without it being followed up with a warning about prostate issues and even prostate cancer. It was common knowledge that if you participated in Testosterone therapy, then you were ultimately going to suffer from prostate issues. Testosterone therapy has represented as a proverbial pact with the devil, by trading short-term sexual and physical rewards for the ultimate development of malignant cancer.

For the longest time, the medical community theorized that testosterone replacement therapy increased one’s risk of prostate cancer. Now, physician, Harvard-based Abraham Morgentaler, MD, FACS, has shown this theory to be inaccurate. Contrary to the notion that restoring testosterone to youthful levels is somehow risky, Dr. Morgentaler meticulously shows that there is also an increased risk of prostate cancer in aging men with low testosterone. This exact information about the dangers of declining testosterone levels was detailed quite a while back, actually, by the Life Extension Foundation.

In his book, Dr. Morgentaler details how a medical myth can be accepted by the medical community, and furthermore, by the masses, it could take years, even decades for that misinformation to be reestablished. For instance, the establishment’s misconception about testosterone and prostate cancer, which has condemned millions of aging men to suffer degenerative diseases caused by dwindling testosterone levels until just a few years ago. It was almost universally believed that Testosterone protocols would lead to some degree of increased risk of prostate issues or even cancer. Fortunately, this belief has been shown to be incorrect, and medical opinion has begun to shift quite dramatically, with good evidence that testosterone therapy is quite safe for the prostate. There is even now a growing concern that low testosterone is a risk for prostate cancer rather than high testosterone.

The very origin of the idea that Testosterone therapy causes prostate cancer is a fantastic story involving Nobel Prize winners, medical breakthroughs, and a critical paradox that took two-thirds of a century to solve.

The relationship of testosterone to prostate cancer has undergone a significant re-evaluation, and all recent evidence has reinforced the position that testosterone therapy is safe for the prostate.

The advantage of living in the 21st century is that you don’t have to take any information at face value. You should always take the time to complete your own research and investigate the information that you are being served as fast. We are fortunate that we live in a time where we can take charge and find answers and details to information we would not have had access to 10 years ago. Especially taking into account how contradicting and negative most of the information regarding the health of your prostate and testosterone therapy. It’s imperative that you take this outdated idea and do your own research.

Imagine if you are living in the fog of low testosterone based on misinformation. How devastating would it be to find out that your knowledge base was completely inaccurate? How would you feel to know that the past decade you could have felt better, looked better or been better?

Don’t let that happen to you. At AAI, we process comprehensive panels to ensure that you are healthy enough to undergo hormone therapy and keep unwanted side effects at bay. Furthermore, we schedule periodic follow-ups, based on your program, to check and see how your hormones are progressing while on therapy, to ensure your dosage is just right for you throughout the duration of your program.

Call us for more information or fill out the Medical History Form located in our header.

We look forward to hearing from you.

testosterone-injections

 

Testosterone Injections is the most common treatment for men going through andropause. This therapy may provide help and relief from the symptoms and help improve the quality of life in many cases, also lifestyle changes such as increased exercise, stress reduction, and proper nutrition also help.

Testosterone therapy is available in different forms, ask your doctor he will help determine which treatment is best for you.

TESTOSTERONE INJECTIONS: This treatment involves doses of bioidentical (Testosterone Cypionate, Testosterone Enanthate, and Testosterone Propionate).

TESTOSTERONE PATCHES: People who wear a piece containing testosterone receive the hormone through the skin. The patches allow a slow, steady release of testosterone into the bloodstream.

TESTOSTERONE GEL: This treatment is also applied directly to the skin, usually on the arms. Because the gel may transfer to other individuals through skin contact, a person must take care to wash the gel from the hands after each application.

TESTOSTERONE CAPSULES: This is yet another option for testosterone replacement. Men with liver disease, poor liver function, severe heart or kidney disease, or too much calcium in their blood should avoid testosterone capsules.

Follow-up visits with your doctor will be necessary after the initial treatment begins. At follow-up visits, your doctor will check your response to the treatment and make adjustments, if necessary.

**NOTE**  The content contained in this blog is subject to interpretation and is the opinion of the content writer.  We do not claim it to be fact.  We encourage you to consult a medical doctor before taking any prescribed medications or supplements.