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January 9, 2018 by Joseph Fermin 0 Comments

26 Foods That Naturally That Boost Testosterone Levels 0 (0)

Top 26 Boost Testosterone Levels

Boost Testosterone Levels: To learn how to Boost Testosterone Levels and maintain testosterone level. We explain how to increase testosterone. This Hormone is the most potent ways to increase testosterone. Every man needs eating for higher Testosterone.

Testosterone is a male intercourse hormone that impacts how to increase testosterone -more than merely intercourse force, This is natural testosterone boosting food. The hormone is likewise chargeable for bone and muscle fitness, sperm production, and hair increase.Men need best foods for testosterone. You could lose testosterone as you age, in addition to from continual ailments.

 

Girls naturally have lower tiers of testosterone for the duration of their lives; their our bodies are more touchy to the hormone, and their fitness relies upon on the stability of testosterone, estrogen, and progesterone.

Alongside your doctor’s recommendations, you may don’t forget capacity testosterone-boosting meals as a herbal complement to low-Testosterone remedies. Foods that increase testosterone. Two type of nutrients which might be mainly crucial to your weight loss program is nutrition d and zinc.

You are capable of using natural techniques to natural testosterone supplements and beautify your everyday health without triggering an imbalance in the sensitive hormonal device on your frame.

Testosterone is a male intercourse hormone that impacts greater than merely sex drive. The hormone is also liable for bone and muscle fitness, sperm production, with hair growth and many more. You may lose testosterone as you age, as well as from continual illnesses, Like:

01) Low Testosterone and Motivation
02) Low Testosterone and Sex Drive & Desire
03) Low Testosterone and Depression
04) Low Testosterone and Fatigue
05) Low Testosterone and Erectile Dysfunction
06) Low Testosterone and Cholesterol
07) Low Testosterone and Low Energy
08) Low Testosterone and Memory Loss
09) Low Testosterone and Osteoporosis
10) Low Testosterone and Wounds & Illness
11) Low Testosterone and Muscle Mass
12) Low Testosterone and Sleep Disturbances
13) Low Testosterone and Thyroid Dysfunction
14) Low Testosterone and Weight Gain

Here we are trying to understand what type supplements to increase testosterone boosting foods. Doctors recommended Testosterone boosting foods or testosterone supplements are:

01) Oyster
02) Garlic
03) Pomegranate
04) Eggs
05) Tuna
06) Spinach
07) Coconut
08) Cabbage
09) Brazil nuts
10) Honey
11) Cruciferous vegetables
12) Watermelon
13) Almond
14) Avocado
15) Grapes
16) Banana
17) Beef
18) Pumpkin seed
19) Asparagus
20) Citrus
21) Beans
22) Yolk
23) Onion
24) Broccoli
25) Ginger
26) Meat

 

testosterone-injections

 

Testosterone Injections is the most common treatment for men going through andropause. This therapy may provide help and relief from the symptoms and help improve the quality of life in many cases, also lifestyle changes such as increased exercise, stress reduction, and proper nutrition also help.

Testosterone therapy is available in different forms, ask your doctor he will help determine which treatment is best for you.

TESTOSTERONE INJECTIONS: This treatment involves doses of bioidentical (Testosterone Cypionate, Testosterone Enanthate, and Testosterone Propionate).

TESTOSTERONE PATCHES: People who wear a piece containing testosterone receive the hormone through the skin. The patches allow a slow, steady release of testosterone into the bloodstream.

TESTOSTERONE GEL: This treatment is also applied directly to the skin, usually on the arms. Because the gel may transfer to other individuals through skin contact, a person must take care to wash the gel from the hands after each application.

TESTOSTERONE CAPSULES: This is yet another option for testosterone replacement. Men with liver disease, poor liver function, severe heart or kidney disease, or too much calcium in their blood should avoid testosterone capsules.

Follow-up visits with your doctor will be necessary after the initial treatment begins. At follow-up visits, your doctor will check your response to the treatment and make adjustments, if necessary.

December 22, 2017 by Joseph Fermin 0 Comments

The Truth About Testosterone Decrease 0 (0)

Why Does Testosterone Decrease | The Truth About Testosterone

HPTA = Hypothalamic Pituitary Gonadal Axis

This axis produces circulating steroids necessary for male sexual function, fertility, and development.

Prostate and penis are steroid sensitive organs impacted by the regulation of the HPTA.

This reproductive axis consists of three parts:

  • Hypothalamus – produces GnRH (gonadotropin-releasing hormone)
  • Pituitary Gland – GnRH sent to the pituitary gland where it stimulates the synthesis and release of gonadotropic hormones LH and FSH.
  • Testis – Gonads carry LH to the testis where they encourage testosterone production through the testicular Leydig cells
  • Conversion of cholesterol produces testosterone
  • FSH is crucial for spermatogenesis

Dihydrotestosterone (DHT) is the activated 2% of testosterone is free or unbound, with the remainder bound to SHBG (sex hormone-binding globulin), albumin- and cortisol-binding globulin. Bioavailable testosterone is the testosterone that will not attach to SHBG. Testosterone and DHT act on organs.

  • Causes development of secondary sexual characteristics
  • Inhibit secretion of LH and FSH by the pituitary gland, thus stops further testosterone production = negative feedback loop.
  • There exist androgen receptors in the pituitary and the

hypothalamic neurons that bind to testosterone and signal to stop GnRH release

Homeostasis maintained through this loop – once testosterone stops production, this inhibited secretion stops and GnRH again causes LH and FSH release to produce further testosterone. As men age, they undergo hormonal level changes:

  • Testosterone decrease
  • LH and FSH increase
  • Other hormones that decrease: T3, insulin, growth hormone/insulin-like growth factor 1, stimulating thyroid hormone
  • Also an increase in SHBG
  • Dihydrotestosterone levels are unchanged
  • Estrogen levels unchanged

As men age, the decrease in testosterone paired with the increase in SHBG leads to a decline in free, or bioavailable, testosterone. These hormonal changes start in the 30s and are well established by the 50s.

The Purpose of Testosterone injections Therapy:

  • Improve Motivation and Memory Loss
  • Increase Sex Drive & Desire
  • Improve Depression and Energy
  • Improve Cholesterol and Osteoporosis
  • Decrease Erectile Dysfunction
  • Increase Muscle Mass and Better Sleep
  • Improve Wounds healing & Illness
  • Improve Thyroid Dysfunction

 

December 20, 2017 by Joseph Fermin 0 Comments

How Testosterone Affects Fat Loss: Real Science of Low-T 0 (0)

How Testosterone Affects Fat Loss: Real Science of Low-T

Testosterone Affects Fat Loss, As men age, their testosterone levels decline. This increase in SHBG (sex-hormone binding globulin), which binds to testosterone and thus reduces the amount of free testosterone in the body. Low testosterone levels, obesity, and many other health problems, including fatigue, memory problems and decreased muscle and bone mass. So what is the impact of testosterone on the body and how Testosterone Affects Fat Loss?

Testosterone and energy – low levels of testosterone can cause low energy levels. Regaining natural testosterone levels can increase strength and lead to weight loss. Studies have found that testosterone supplementation reduces total body fat percentages. Obesity is related to low testosterone levels in men. Just as testosterone therapy is associated with decreased obesity, losing weight is associated with increased testosterone levels.

An article in 2014 in the journal of Current Opinion in Endocrinology, Diabetes, and Obesity looked at the existing data regarding testosterone therapy in overweight and obese men with testosterone deficiency (hypogonadism).

  • Many weight loss supplements have dangerous side effects or are ineffective
  • Looked at weight loss, BMI, waist circumference and body composition
  • Evaluated long-term testosterone therapy
  • About 40% of obese nondiabetic men and 50% of overweight diabetic men over 45 have low levels of free testosterone
  • Many studies have found that testosterone therapy in overweight men helps increased lean body mass, weight loss, decreased BMI and reduced waist circumference.
  • Weight loss is significant and sustained with long-term testosterone therapy
  • Testosterone plays a part in protein, fat and carbohydrate metabolism.
  • Testosterone is involved in mitochondrial function and thus energy production and utilization
  • This interference with energy production is likely why those with low testosterone levels experience a lack of energy
  • Testosterone therapy has been found to increase lipid oxidation and normalize glucose use in the body. It was found to increase strength and motivation.

Weight gain associated with an 88% increase in body fat and a 12% increase in lean body mass (LBM) and weight loss with a 72% decrease in body fat and a 28% decrease in LBM.

  • With testosterone therapy, LBM has been shown to increase.
  • Increased LBM means increased energy expenditure at rest
  • Testosterone therapy with improved cardiometabolic function

Testosterone deficiency decrease in energy metabolism from fat and an increase in energy metabolism from glucose.

  • Testosterone therapy has been shown to increase lipid metabolism

Safety? Safety is the primary concern with testosterone replacement therapy. Possible risks discussed in the literature include:

  • Increased risk of prostate and breast cancer
  • Liver toxicity and tumors
  • Sleep apnea exacerbation
  • Testicular infertility and atrophy

Talking with your doctor before starting testosterone injections therapy is necessary.

Summary: If you are a male struggling to lose weight, testosterone therapy is a promising treatment to help with not only weight loss but for body composition, energy levels and overall health.

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November 14, 2017 by Joseph Fermin 0 Comments

The Danger of Low Testosterone in Women 0 (0)

LOW TESTOSTERONE IN WOMEN’S HEALTH

Low Testosterone in Women’s are full with Television ads, internet ads, magazine ads and radio ads they are all targeting men with products that addressing low testosterone that occurs as we age, but nothing is directing or teaching women about low testosterone, despite being classified as a male hormone, women also produce testosterone.

Testosterone therapy in women has become a hot-button problem issue as women begin to realize the risk of low testosterone levels drop with age for women as well as men. testosterone therapy is used to treat the symptoms of testosterone deficiency in perimenopause, premenopause and postmenopausal in women, as research continues to show that healthy testosterone levels are essential for the physical and mental health of both in women and men as well.

Low Testosterone in Women

Which Women’s Can Be at Risk for Low Testosterone

The ovaries are responsible for producing both testosterone and estrogen, as the ovaries age, they produce less estrogen and testosterone. As women enter peri-menopause and pre-menopause, testosterone will be diminished by the age of 30’s, and once a women reach full menopause, it’s common for them to produce 75% less testosterone than they did in the there 21’s. Every woman becomes at risk of low testosterone as she ages, and women who go through hysterectomy or oophorectomy have an even higher chance of dealing or having with low testosterone levels.

What are the Symptoms of Peri-Menopause?

Peri-menopause occurs when a woman’s hormonal cycle transitions toward pre-menopause and infertility begin. It often starts in women in their late-30’s and can last for up to 11 years; the average duration is ~4 years. During the peri-menopause, menses become less frequent, and the symptoms typically associated with menopause.

The most common symptoms of peri-menopause are:

  • Hot flashes and Reduced sex drive
  • Discomfort and dryness during sex
  • Fatigue and Problems sleeping
  • Mood swings and Migraines
  • Severe premenstrual syndrome
  • Irregular periods and Breast tenderness
  • An urgent need to urinate
  • Urine leakage, particularly when sneezing or coughing

Dangers of Testosterone Deficiencies in Women as we Age

Women who begin experiencing low testosterone may notice many of the same symptoms that men deal with.
With Low levels of testosterone in women often lead to an increased risk of :

  • Reduced fertility
  • Increased risk of Polycystic Ovarian Syndrome (PCOS)
  • Psoriasisosteoporosis, since low T levels can leach away strength from the skeleton.

Low levels can also lead to an increased risk of gaining weight since low testosterone has linked to control the fat mass in women.

A report published in the Journal for Women’s Health even showed that low testosterone in women’s could be a risk factor for heart disease. Since the number one killer is a cardiovascular disease in women and men, this is the importance of balanced your hormones, including testosterone, progesterone, and estrogen,

What’re The Benefits of Progesterone, Estrogen, and Testosterone Therapy?
Women With Low Progesterone May Experience Symptoms As:

  • Insomnia, trouble sleeping, waking up in the middle of the night
  • Fuzzy Thinking” ­ is misplacing keys, forgetting where the car is parked, feeling overwhelmed.
  • Worsening PMS with more substantial, more painful periods
  • Headaches are increasing in frequency, new onset migraines.

Testosterone is an essential as a woman’s testosterone level declines in peri­menopause.
Women may experience symptoms such as;

  • Decreased libido
  • Inability to orgasm
  • Reduced the sense of well­being, energy, and sex drive
  • Dysphoria and much more

The final hormone is perimenopause is estrogen. This will occurs late in perimenopause, signaling the transition into early premenopause or menopause.
Symptoms of low estrogen can include:

  • Hot Flashes
  • Night Sweats
  • Pain during intercourse
  • Thinning, drooping skin
  • Recurrent urinary tract infections

Testosterone has the potential to relieve these symptoms. Studies show that treating women with testosterone can significantly improve their sex drive.

For women going through perimenopause, and premenopause or menopause, testosterone therapy often provides symptom relief. Studies show that testosterone therapy in women can relieve the symptoms of menopause, including:

  • Urinary urgency
  • Incontinence
  • Vaginal dryness
  • and hot flashes

An increasing number of women are being diagnosed with low testosterone in women’s. Although men make and need a lot more testosterone than women, it is still very important for a normal androgen response in women.

Even though many of the risks of low testosterone in women’s are similar in men, there are several female-specific risks:

  • Reduced fertility
  • Increased risk of Polycystic Ovarian Syndrome (PCOS)
  • Psoriasis

Because low testosterone in women’s generally occurs around middle age, it is often accompanied by low estrogen at the pre-menopausal period. This combination of two low hormones leads to a high rate of heart disease, bone fractures, and vaginal atrophy.

November 2, 2017 by Joseph Fermin 0 Comments

What Causes Low Testosterone and The Role Of Testosterone 0 (0)

What Causes Low Testosterone

The Danger of Low Testosterone, Risks Associated with Low hGH in Men, HGH Side Effects, What Causes Low Testosterone

What is the role of testosterone?

Causes Low Testosterone is the most critical hormone in men. Low, testosterone (hypogonadism) can cause and is responsible for the male characteristics & helps maintain our sex drive, sperm production, body hair, bone, and muscle.

What’re other causes low testosterone?

(e.g., trauma, castration, radiation or chemotherapy), hormonal disorders like (pituitary tumors or diseases, high levels of prolactin), or other disorders like (chronic liver and kidney disease, HIV/AIDS, too much body fat, and type 2 diabetes and associated obesity).

How is low testosterone diagnosed and tested?

Your doctor will use blood tests to see if the total testosterone level is within the normal range. Will be 300 to 1,000 ng/dL, but this may differ depending on the laboratory and a physical exam, To diagnose low testosterone, you may need more than one early-morning (7 AM — 10 AM) blood test and, sometimes, other analyses of the pituitary gland.

How is low testosterone treated?

There are several methods of testosterone replacement; Testosterone Injections is the best meted to get the full benefits of the therapy:

• Injections
• Patches
• Gel
• Pellets

The best method will depend on the cause of the problem, the patient’s preference and tolerance, and cost.

What should you do with this information?

If you have symptoms talk with one of our specialist, an expert in hormones, can help you determine the causes. Be open with our doctor about your medical history, all prescription and nonprescription drugs, any sexual problems, and any significant changes in your life.

Many lifestyle choices and decisions can also negatively impact our natural testosterone production, including:

• Injury to the body. Any physical or psychological trauma can significantly hinder the natural production of testosterone in men.

• Getting married or having children. High testosterone in men prepares us to find a mate and have a family.

Once those goals have been met, our bodies are programmed to lower testosterone production:

• Depression
• Excessive drug use
• Excessive marijuana use
• Extreme opiate use
• Excessive alcohol consumption
• High-stress levels
• Lack of sleep or good quality sleep
• Low self-esteem
• Negative thoughts
• Unnatural glandular issues
• And much, much more…

Low Hormone Symptoms also will depend on the cause of the problem:

  • Weight Gain

Causes Low Testosterone Once we hit age 30 the levels of many of our hormones begin to decline. The lean body mass (LBM) of our organs starts to decrease, whereas the adipose (or fat) mass. Between the ages of 30 and 75, the liver, kidneys, brain, and pancreas atrophy by an average of 30%. The LBM declines by ~5% in men and 2.5% in women per decade. Meanwhile, the percent of body fat increases in both sexes during the same period.

  • Depression

Depression impacts all of us at one time or another. It simply isn’t possible to have everything go well all the time. Plenty of people may seem to be lucky and prosperous, with the world at their fingertips. Sadly, that surface appearance completely masks the symptoms of low motivation and/or depression. Depression can hit you like a ton of bricks. The stigma associated with being a man with symptoms of depression can be even more demoralizing and add insult to injury. Most men refuse to admit to feelings of depression, let alone confront or deal with the causative issues.

  • Muscle Mass and Strength

Once we hit 30, the lean body mass of our organs begins to decrease, whereas the fat mass increases. Between the ages of 40 and 80, the lean body mass declines by ~5% per decade in men and 2.5% per decade in women. Meanwhile, at the same time, the body fat in both sexes increases. These physiological changes are not just an affront to vanity but are a threat to health and longevity. First, aerobic power is directly connected to the amount of lean body mass. Second, this shrinkage of vital organs means that they cannot do their jobs as well, whether it be the heart pumping, the muscles lifting, or the kidneys clearing metabolic waste from the blood. Third, the risk of heart attack, hypertension, and diabetes with an increasing abdominal fat mass.

  • Fatigue

We all have busy lives and are constantly on the go. Although most people experience sleep problems at some point in their life, one can usually identify the cause of the temporary tiredness and remedy it quickly with good quality rest. Extreme, long-term fatigue is a different story. You do not know what is causing it, and it can gradually destroy your motivation, concentration, and energy levels. Often, the people in your life do not understand what how debilitating fatigue can be.

  • Sleep Disturbances

Sleep disturbance affects every facet of our existence. Many sleep-related problems can be overcome with testosterone therapy. Men with lower testosterone levels have reduced sleep efficiency, with increased nocturnal awakenings and less slow-wave (REM) sleep. Studies have even shown that sleep disturbance caused by sleep apnea, a chronic breathing problem, may be linked to low testosterone levels.

  • Erectile Dysfunction

One of the worst aspects of getting older is erectile dysfunction (ED), which causes a reduced ability to perform in the bedroom and lowers your sex drive. One of the main causes of age-related sexual dysfunction is the changes in your metabolism and hormone levels, including reduced testosterone production. Numerous studies have also linked low GH and IGF-I levels to ED.

  • Decreased Sex Drive and Desire

Low testosterone often leads to a decreased sex drive. Although it is the dominant hormone in men, testosterone also plays a significant role in women. Contrary to popular belief, low libido is not related to the frequency of sexual activity or the amount of satisfaction achieved. Instead, it is determined by the body’s signal indicating sexual desire. This signal declines with age due to the body’s decreased production of testosterone.

  • Motivation

Motivation is important for getting the most out of life; without motivation, even the most routine task can be daunting. Many people to assume if they get a good night sleep they will feel rejuvenated in the morning. When you wake your head is immediately flooded with thoughts of what you need to accomplish during the day, even if you sleep well. You might then organize your day, plan your activities, and create a map of the tasks you need to accomplish in order to have a productive day. However, if you do not have motivation then all the preparation in the world will not help you execute your plan for a productive day.

  • High Cholesterol

Undetected and untreated high cholesterol is a silent killer! High Cholesterol can lead to an assortment of different health problems, including heart attack, stroke, and death. Although high cholesterol is associated with overweight individuals, you can be thin and still have high cholesterol. GH is an important regulator of LDL and total cholesterol, as well as triglycerides. It lowers diastolic blood pressure by reducing the resistance of arteries and capillaries that carry blood throughout the body. Multiple studies have shown that GH can reduce levels of LDL, or bad, cholesterol.

  • Low Energy

Many symptoms of aging are a direct or indirect result of diminishing GH and testosterone levels, including low energy and fatigue. By the age of 30, most people are GH-deficient, which can result in somatotropin deficiency syndrome (SDS). Somatotropin is another name for GH. Without GH therapy, GH levels continue to decline, which is sometimes referred to as the somatopause.

  • Memory Loss

Hopefully, you have been skimming through the many pages of our website to try and educate yourself about how to take charge of your life, maximize your potential, and experience life to the fullest. The only way you will ever be able to do this is if you are feeling your best, are able to produce your best, and give your best!

  • Osteoporosis and Bone Mass

Osteoporosis is the gradual thinning that makes bones brittle and porous which in turn makes them more prone to fracture. If affects approximately 10 million adults in the United States, and is more common in women than men. Of people older than 50 years of age, one in two women and one in eight men are predicted to have an osteoporosis-related fracture in their lifetime. Individuals of Caucasian and Asian ethnicity are also at a high risk.

  • Wound Healing

Think about your children or yourself when you were a child. Do you remember how many times you fell down and scraped your knee? Your arms and legs always seemed to be wearing red badges of courage. Then, a scab would form and then soon disappear, leaving absolutely no trace of the injury. However, when you are young your cells regenerate and repair at a much faster pace, and so your wounds heal more quickly and your bones knit more rapidly. All these processes are under the control of GH and other growth factors. Although GH supplementation won’t restore your healing capacity to that you experienced as a child, it will dramatically accelerate the healing process.

  • Thyroid

The thyroid and adrenal glands regulate multiple functions throughout the body. If thyroid hormone and cortisol levels are not right, the rest of the body will not function correctly; these critical hormones are just as important as estrogen, progesterone, testosterone, and growth hormone.

(more…)

July 17, 2017 by Joseph Fermin 1 Comment

All You Need to Know About Testosterone Benefits 0 (0)

What You Need to Know About Testosterone Benefits

Right around the age of 30, most men experience a significant “shift” in their lives. They can’t tell what it is. They can’t quite put their finger on it. All they know is, something has “changed”. Usually, men attribute it to being “tired” from working so hard, keeping up with the kids and maintaining their household. The supposition is, “if I can only get one good nights rest, I’ll be all better the next day,” but that day never comes. (*) Individual Results May Vary & Are Not Guaranteed

(more…)

June 7, 2017 by Joseph Fermin 4 Comments

Improve Symptoms of Depression and Anxiety 0 (0)

Exercise can ease symptoms of depression and anxiety

Depression and Anxiety. Exercise can improve symptoms of depression and anxiety. Even small amounts of exercise help. These realistic tips and goals can help you get started and stick with it.

If you have depression or anxiety, you might find your doctor prescribing a regular dose of exercise in addition to medication or psychotherapy. Exercise isn’t a cure for depression or anxiety. But its psychological and physical benefits can improve your symptoms.

“It’s not a magic bullet, but increasing physical activity is a positive and active strategy to help manage depression and anxiety, ” says Kristin Vickers-Douglas, Ph.D., a psychologist at Mayo Clinic, Rochester, Minn.

When you have depression or anxiety, exercising may be the last thing you think you can do. But you can overcome the inertia. Here’s a look at how exercise can ease symptoms of depression and anxiety. Plus, get realistic tips to get started and stick with exercising.

How exercise helps depression and anxiety

Exercise has long been touted as a way to maintain physical fitness and help prevent high blood pressure, diabetes, obesity and other diseases. A growing volume of research shows that exercise also can help improve symptoms of certain mental conditions, such as depression and anxiety. Exercise also may help prevent a relapse after treatment for depression or anxiety.

Research suggests that it may take at least 30 minutes of exercise a day for at least three to five days a week to significantly improve symptoms of depression. However, smaller amounts of activity — as little as 10 to 15 minutes at a time — have been shown to improve mood in the short term. “So, small bouts of exercise may be a great way to get started if it’s initially too difficult to do more, ” Dr. Vickers-Douglas says.

Just how exercise reduces symptoms of depression and anxiety isn’t fully understood. Researchers believe that exercise prompts changes in both mind and body.

Some evidence suggests that exercise positively affects the levels of certain mood-enhancing neurotransmitters in the brain. Exercise may also boost feel-good endorphins, release tension in muscles, help you sleep better and reduce levels of the stress hormone cortisol. It also increases body temperature, which may have calming effects. All of these changes in your mind and body can improve such symptoms as sadness, anxiety, irritability, stress, fatigue, anger, self-doubt and hopelessness.

If you exercise regularly but depression or anxiety still impairs your daily functioning, seek professional help. Exercise isn’t meant to replace medical treatment of depression or anxiety.

The benefits of exercise for depression and anxiety

Exercise has numerous psychological and emotional benefits when you have depression or anxiety. These include: 

•Confidence. Engaging in physical activity offers a sense of accomplishment. Meeting goals or challenges, no matter how small, can boost self-confidence at times when you need it most. Exercise also can make you feel better about your appearance and your self-worth.

•Distraction. When you have depression or anxiety, it’s easy to dwell on how badly you feel. But dwelling interferes with your ability to problem solve and cope in a healthy way. The dwelling also can make depression more severe and longer lasting. Exercise can provide a good distraction. It shifts the focus away from unpleasant thoughts to something more pleasant, such as your surroundings or the music you enjoy listening to while you exercise.

•Interactions. Depression and anxiety can lead to isolation. That, in turn, can worsen your condition. Exercising can create opportunities to interact with others, even if it’s just exchanging a friendly smile or greeting as you walk around your neighborhood.

•Healthy Coping. Doing something beneficial to manage depression or anxiety is a positive coping strategy. Trying to feel better by drinking alcohol excessively, dwelling on how badly you feel, or hoping depression and anxiety will go away on their own aren’t helpful coping strategies.

Tips to start exercising when you have depression or anxiety

Of course, knowing that something’s good for you doesn’t make it easier to actually do it. With depression or anxiety, you may have a hard enough time just doing the dishes, showering or going to work. How can you possibly consider getting some exercise?

Here are some steps that can help you exercise when you have depression or anxiety: 

•Get your doctor’s support. Some, but not all, mental health professionals have adopted exercise as a part of their treatment suggestions. Talk to your doctor or therapist for guidance and support. Discuss concerns about an exercise program and how it fits into your overall treatment plan.

•Identify what you enjoy doing. Figure out what type of exercise or activities you’re most likely to do. And think about when and how you’d be most likely to follow through. For instance, would you be more likely to do some gardening in the evening or go for a jog in the pre-dawn hours? Go for a walk in the woods or play basketball with your children after school?

•Set reasonable goals. Your mission doesn’t have to be walking for an hour five days a week. Think about what you may be able to do in reality. Twenty minutes? Ten minutes? Start there and build up. Custom-tailor your plan to your own needs and abilities rather than trying to meet idealistic guidelines that could just add to your pressure.

•Don’t think of exercise as a burden. If exercise is just another “should” in your life that you don’t think you’re living up to, you’ll associate it with failure. Rather, look at your exercise schedule the same way you look at your therapy sessions or antidepressant medication — as one of the tools to help you get better.

•Address your barriers. Identify your individual barriers to exercising. If you feel intimidated by others or are self-conscious, for instance, you may want to exercise in the privacy of your own home. If you stick to goals better with a partner, find a friend to work out with. If you don’t have extra money to spend on exercise gear, do something that is virtually cost-free — walk. If you think about what’s stopping you from exercising, you can probably find an alternative solution.

•Prepare for setbacks and obstacles. Exercise isn’t always easy or fun. And it’s tempting to blame yourself for that. People with depression are especially likely to feel shame over perceived failures. Don’t fall into that trap. Give yourself credit for every step in the right direction, no matter how small. If you skip exercise one day, that doesn’t mean you’re a failure and may as well quit entirely. Just try again the next day.

Sticking with exercise when you have depression or anxiety

Launching an exercise program is hard. Sticking with it can be even harder. One key is problem-solving your way through when it seems like you can’t or don’t want to exercise.

“What would happen if you went out to your car and it wouldn’t start? ” Dr. Vickers-Douglas asks. “You’d probably be able to very quickly list several strategies for dealing with that barrier, such as calling an auto service, taking the bus, or calling your spouse or friend for help. You instantly start problem-solving. ”

But most people don’t approach exercise that way. What happens if you want to go for a walk but it’s raining? Most people decide against the walk and don’t even try to explore alternatives. “With exercise, we often hit a barrier and say, ‘That’s it. I can’t do it, forget it,’ ” Dr. Vickers-Douglas says.

Instead, problem solve your way through the exercise barrier, just as you would other obstacles in your life. Figure out your options — walking in the rain, going to a gym, exercising indoors, for instance.

“Some people have the idea that being physically active is supposed to be easy and natural, ” Dr. Vickers-Douglas says. “Some think of it as just having enough willpower. But that really oversimplifies it and can make us feel like failures. You can’t just rely on willpower. Identify your strengths and skills and apply those to exercise. ”

Article original printed (November 5, 2005)

Testosterone Injections – Curious about testosterone injections Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698

Testosterone Therapy Information

November 30, 2016 by Joseph Fermin 1 Comment

The Relationship Between Hormones and Stress 0 (0)

Hormones and Stress

Hormones and Stress in the holiday season are upon us! Although this can a wonderful time filled with love and laughter, it can also significantly increase the day-to-day stresses experienced by many people; this can easily turn into chronic stress. Did you know that chronic stress can have a significant impact on your normal hormonal responses? Read on to learn more about the effects stress can have on your body and what you can do about it.

Hormones and Stress

The Hormones and Stress feeling that we all know so well is part of the body’s normal response to a real or perceived threat. However, your body does not differentiate between serious physical threats and “normal” pressures, and so a heavy workload or demands from your family can build up over time and have a detrimental effect on your health.

The stress response is commonly known as the “fight or flight” response, and it begins in the brain. When a stress is perceived, the amygdala sends a signal to the hypothalamus, which activates the sympathetic nervous system and triggers the release of adrenaline from the adrenal glands into the bloodstream. Adrenaline then accelerates the heartbeat to pump more blood to the muscles in preparation for “flight.” In addition, the pulse, blood pressure, and breathing rate all increase to enhance the amount of oxygen inhaled. Other senses, such as sight and hearing, become sharper.

The Normal Stress Response

 

During the second phase of the stress response, the hypothalamus releases corticotropin-releasing hormone (CRH), which stimulates the release of adrenocorticotropic hormone (ACTH). ACTH then stimulates the release of cortisol from the adrenal glands, which ensures that the body remains on “high alert.” Cortisol levels remain elevated until the threat passes; the stress response is then shut down once the brain perceives that the threat is no longer there (http://www.health.harvard.edu/staying-healthy/understanding-the-stress-response).

Hormones and Stress

The Effects of Stress

Prolonged periods of stress prevent the shut-down of the normal stress response because the body remains on high-alert and producing cortisol. The long-term exposure to cortisol and other Hormones and Stress has a number of negative effects throughout the body, including:

  1. In the respiratory system, the accelerated breathing rate could lead to asthma or panic attacks (http://www.apa.org/helpcenter/stress-body.aspx).
  2. In the cardiovascular system, prolonged periods of an elevated heart rate and increased blood pressure can increase the risk of cardiovascular disease, heart attack, and stroke.
  3. In the liver, the increased levels of cortisol stimulate the production of glucose in anticipation of increased energy demands. Such prolonged exposure to elevated blood glucose levels might increase the risk of metabolic syndrome and type 2 diabetes.
  4. Some animal studies have suggested that chronic stress can reduce testosterone levels and sperm production and maturation in men; it can even lead to erectile dysfunction and impotence.
  5. In women, chronic stress can lead to an irregular menstrual cycle, worsened premenstrual syndrome symptoms, and reduced libido.
  6. Stress can also dampen the immune system.
  7. Emotionally, stress can affect your sleep, increase irritability, anxiety, and depression, and reduce concentration.

How to Reduce the Effects of Stress

There is no need to worry: there is a lot you can do to counteract the natural stress responses that occur at this time of year. It is important to understand what makes you stressed, as well as what makes you relax. For example, there are several lifestyle changes that can help reduce stress (http://www.webmd.com/balance/stress-management/stress-management-relieving-stress):

  1. Take time out to do something you enjoy
  2. Express your feelings
  3. Use relaxation techniques such as meditation
  4. Exercise regularly; exercise is one of the best ways of reducing stress

Because many of the symptoms of chronic stress are also associated with low hormones, such as sleep loss, fatigue, and low testosterone levels, we recommend getting your Hormones and Stress levels checked if you experience any prolonged, unusual or unexplained stress. At AAI Clinic, we can measure your Hormones, Testosterone Injections, and Stress and make recommendations regarding any hormone replacement therapy or supplements that could alleviate your stress-related symptoms.

Testosterone Injections – Curious about testosterone injections Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-LowT (5698)

References

  1. Golbidi, S., J.C. Frisbee, and I. Laher, Chronic stress impacts the cardiovascular system: animal models and clinical outcomes. Am J Physiol Heart Circ Physiol, 2015. 308(12): p. H1476-98.
  2. Bergmann, N., F. Gyntelberg, and J. Faber, The appraisal of chronic stress and the development of the metabolic syndrome: a systematic review of prospective cohort studies. Endocr Connect, 2014. 3(2): p. R55-80.
  3. Kalaitzidou, I., et al., Stress management and erectile dysfunction: a pilot comparative study. Andrologia, 2014. 46(6): p. 698-702.
  4. Gannon, L., et al., Perimenstrual symptoms: relationships with chronic stress and selected lifestyle variables. Behav Med, 1989. 15(4): p. 149-59.
  5. Golkar, A., et al., The Influence of Work-Related Chronic Stress on the Regulation of Emotion and on Functional Connectivity in the Brain. PLoS ONE, 2014. 9(9): p. e104550.

November 16, 2016 by Joseph Fermin 5 Comments

The Health Benefits Of Raw Cacao 0 (0)

The Benefits Of Raw Cacao

Today’s media is full of reports about so-called “superfoods.” While most of these reports are based on some level of fact, misrepresentation or poor interpretation of medical and scientific findings often leads to misinformation and sensational yet misleading headlines. A prime example of this is raw cacao. The health benefits of raw cacao are astounding; however, this, unfortunately, does not necessarily mean that eating a bar of milk chocolate each day will have the same effects. Read on to learn more about the ways in which raw cacao can improve your health and how to take full advantage.

What is Raw Cacao?

Cacao-based products are made from cacao beans and include cacao powder, nibs, paste, and butter. raw cacao

When purchasing raw cacao products such as powder, it is important to understand the differences between raw cacao powder and the more common cocoa powder. Raw cacao powder is very pure. It is made from raw, unroasted cocoa beans via a process known as cold pressing, which removes the fat in the form of cacao butter; much of the bean and nutrients remain intact.

Cacao is one of the best sources of flavonoids (which are potent antioxidants) available, which means that it has huge health benefits. It is also rich in protein, cholesterol-free and monounsaturated fats, fiber, natural carbohydrates, and minerals (including zinc, iron, potassium, magnesium, copper, manganese, and calcium).

Cocoa powder is produced in a similar way to cacao powder, except that it undergoes high-temperature processing during production. Although it retains significant health benefits, the high temperatures used to destroy some of the nutritional value. As cocoa undergoes further processing to make reduced-strength dark chocolate and milk chocolate, increasing amounts of the nutrients are removed. Therefore, raw cacao powder, cocoa powder, or very strong dark chocolate are recommended for optimal health benefits.

what-is-raw-cacao

Cardiovascular benefits

Many people are at an increased risk of cardiovascular events as they age. The good news is that the consumption of certain foods can help reduce this risk. Cocoa-based products can have significant beneficial effects on the cardiovascular system by reducing cardiovascular risk and atherosclerosis, improving circulation, lowering the levels of LDL (bad) and increasing the levels of HDL (good) cholesterol, and reducing blood pressure. Many of these effects are caused by the anti-inflammatory and antioxidant properties of the flavonoids.

  • Cacao- and cocoa-based products can reduce hypertension. For example, the Cocoa, Cognition, and Aging (CoCoA) Study was performed in 90 elderly individuals who received cocoa-based drinks with high, medium, or low flavonoid content. Blood pressure was reduced significantly in patients that received high- or medium-content cocoa compared with those that received low flavonoid cocoa [1]. The subjects also exhibited improved insulin resistance and reduced lipid peroxidation.
  • Cardiovascular function. A recent study assessed vascular stiffness in healthy younger (<35) and older (50–80) men who drank cocoa or a control drink twice a day for two weeks. The subjects who drank cocoa exhibited significantly improved cardiovascular function, as measured by improved endothelial function, blood pressure, and vascular stiffness [2]. A second similar study confirmed these effects and also indicated that the consumption of high-flavonoid chocolate improved platelet aggregation (an indicator of the ability of the blood to form clots) compared with low flavonoid chocolate [3].
  • Cholesterol. Several studies have investigated the ability of cocoa and cacao to improve cholesterol. For example, consuming 400 g cocoa powder with 500 ml skimmed milk per day increased HDL and lowered LDL cholesterol levels in elderly subjects at high risk of cardiovascular disease [4]. Similar observations were made in young healthy and hypercholesterolemic subjects [5] and in elderly healthy individuals [6].

cacao

Cognitive function

The available data suggest that cocoa and cacao could help protect against cognitive decline in aging individuals.

  • In the same CoCoA study described above, subjects that received cocoa with a high or medium flavonoid content had significant improvements in two different measures of cognitive function: a trail making test and a verbal fluency test. The improvements were greatest in the high flavonoid vs. the intermediate flavonoid group. However, there were no improvements in the mini-mental state evaluation among groups [1].
  • Cocoa and cacao might also protect against dementia and related diseases such as Alzheimer’s disease [7].

Metabolic Effects

The risk of metabolic diseases often increases as we age, and conditions such as diabetes and obesity are associated with reduced mortality. Luckily, cocoa could help reduce the risk of these conditions and their symptoms. Possibly the most important metabolic effect of cocoa is its ability to improve insulin sensitivity. In one study, subjects received dark or white chocolate (with high and zero flavonoid content, respectively), and insulin sensitivity was assessed using glucose tolerance tests and the quantitative insulin sensitivity check index. Dark, but not white, chocolate significantly improved both measures of insulin sensitivity and reduced blood pressure [8].

Hormonal Changes

The symptoms of many aging-related diseases have been linked to reduced hormone levels over time. Therefore, improving natural hormone production can reduce the symptoms of many aging-related diseases. Cocoa can have beneficial effects on the production of several hormones.

  • Testosterone Injections. Cocoa and cacao contain high concentrations of zinc, which has been shown to increase testosterone production [9].
  • Stress hormones. We all know that nice, relaxed feeling that occurs when we eat a delicious, rich piece of dark chocolate. It turns out that there is a physiological reason for this! Cocoa can potently inhibit the release of the stress hormone cortisol. Healthy men aged 20–50 who consumed a single piece of dark chocolate had a significantly reduced response to a psychosocial stressor. These effects were caused by inhibiting the release of the stress hormones cortisol and epinephrine from the adrenal gland [10].

So, there you have it! Cocoa really is a super-food. It is not only delicious but, when eaten in unprocessed forms, it has significant health benefits.

Testosterone Injections – Curious about testosterone injections Therapy? Read more about what you can expect from this treatment and contact us for more information (866) 224-5698

References

[1] D. Mastroiacovo, C. Kwik-Uribe, D. Grassi, S. Necozione, A. Raffaele, L. Pistacchio, R. Righetti, R. Locale, M.C. Lechiara, C. Marini, C. Ferri, G. Desideri, Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging (CoCoA) Study–a randomized controlled trial, The American journal of clinical nutrition, 101 (2015) 538-548.

[2] C. Heiss, R. Sansone, H. Karimi, M. Krabbe, D. Schuler, A. Rodriguez-Mateos, T. Kraemer, M.M. Cortese-Krott, G.G. Kuhnle, J.P. Spencer, H. Schroeter, M.W. Marx, M. Kelm, Impact of cocoa flavanol intake on age-dependent vascular stiffness in healthy men: a randomized, controlled, double-masked trial, Age (Dordrecht, Netherlands), 37 (2015) 9794.

[3] G. Rull, Z.N. Mohd-Zain, J. Shiel, M.H. Lundberg, D.J. Collier, A. Johnston, T.D. Warner, R. Corder, Effects of high flavanol dark chocolate on cardiovascular function and platelet aggregation, Vascular Pharmacology, 71 (2015) 70-78.

[4] N. Khan, M. Monagas, C. Andres-Lacueva, R. Casas, M. Urpi-Sarda, R.M. Lamuela-Raventos, R. Estruch, Regular consumption of cocoa powder with milk increases HDL cholesterol and reduces oxidized LDL levels in subjects at high-risk of cardiovascular disease, Nutrition, metabolism, and cardiovascular diseases : NMCD, 22 (2012) 1046-1053.

[5] S. Martinez-Lopez, B. Sarria, J.L. Sierra-Cinos, L. Goya, R. Mateos, L. Bravo, Realistic intake of a flavanol-rich soluble cocoa product increases HDL-cholesterol without inducing anthropometric changes in healthy and moderately hypercholesterolemic subjects, Food & function, 5 (2014) 364-374.

[6] N. Neufingerl, Y.E. Zebregs, E.A. Schuring, E.A. Trautwein, Effect of cocoa and theobromine consumption on serum HDL-cholesterol concentrations: a randomized controlled trial, The American journal of clinical nutrition, 97 (2013) 1201-1209.

[7] L. Dubner, J. Wang, L. Ho, L. Ward, G.M. Pasinetti, Recommendations for Development of New Standardized Forms of Cocoa Breeds and Cocoa Extract Processing for the Prevention of Alzheimer’s Disease: Role of Cocoa in Promotion of Cognitive Resilience and Healthy Brain Aging, Journal of Alzheimer’s disease : JAD, 48 (2015) 879-889.

[8] D. Grassi, C. Lippi, S. Necozione, G. Desideri, C. Ferri, Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons, The American journal of clinical nutrition, 81 (2005) 611-614.

[9] C.D. Hunt, P.E. Johnson, J. Herbel, L.K. Mullen, Effects of dietary zinc depletion on seminal volume and zinc loss, serum testosterone concentrations, and sperm morphology in young men, The American journal of clinical nutrition, 56 (1992) 148-157.

[10] P.H. Wirtz, R. von Kanel, R.E. Meister, A. Arpagaus, S. Treichler, U. Kuebler, S. Huber, U. Ehlert, Dark chocolate intake buffers stress reactivity in humans, Journal of the American College of Cardiology, 63 (2014) 2297-2299.

November 8, 2016 by Joseph Fermin 6 Comments

What are the Symptoms of Peri-menopause 0 (0)

What is the Peri-menopause?

As women, our bodies go through dramatic changes as we age, and these changes are caused by our hormones. Perimenopause is the time of a woman’s life when her hormonal cycle slows, her fertility reduces, and periods become less common as she heads toward menopause. It can be a very stressful time because it affects her physical and emotional state.

To understand what causes the peri-menopause and how to best reduce the symptoms, it is important to appreciate the changes that occur in the female body during aging. There are four main stages in a woman’s hormonal life:

Puberty

Puberty is the process of sexual maturation; it normally begins around the age of 11 and lasts for several years. Generally, it begins with breast development, followed by the growth of pubic hair and finally menstruation.

The Reproductive Years

The reproductive years begin with the onset of menstruation and persist until peri-menopause. They are characterized by the menstrual cycle, which controls a woman’s fertility. The menstrual cycle is primarily governed by fluctuations in the levels of the hormones that control ovulation and regulate the thickness of the uterine lining to prepare for the implantation of a possible fertilized egg.

  • The hypothalamus secretes gonadotropin hormone-releasing hormone (GnRH), which stimulates the pituitary gland to release follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
  • FSH stimulates follicles in the ovaries to prepare an egg for maturation and release, which includes the secretion of estrogen to prepare the uterus for implantation.
  • LH triggers ovulation, or the release of an egg from the ovaries, which results in the production and release of progesterone and additional estrogen to prepare the body for fertilization and pregnancy [1].

Menopause

Perimenopause

Perimenopause occurs when a woman’s hormonal cycle transitions toward menopause and infertility begin. It often starts in women in their late-40’s and can last for up to 11 years; the average duration is ~4 years. During the peri-menopause, menses become less common and the symptoms typically associated with menopause (discussed below) begin.

The changes that occur during menopause are caused by altered hormone levels. A woman remains fertile only as long as her ovaries produce and secrete eggs via a process known as ovulation. Since there are a finite number of eggs, female fertility essentially has an expiration date. The production of estrogen and progesterone relies upon ovulation, which means that hormone production is diminished significantly once eggs are no longer released.

Hormonally, the peri-menopause is defined by persistently increased LH and FSH levels and very low estrogen and progesterone levels. Testosterone secretion can also decline by approximately 50% during peri-menopause [2].

Menopause

Menopause officially starts one year after a woman’s last period. Menopausal women produce very high levels of FSH but low levels of estrogen and progesterone. They are no longer fertile and are at a higher risk of diseases such as osteoporosis and cardiovascular disease because of the reduced hormone concentrations [3].perimenopause

What are the Symptoms of Peri-Menopause?

The most common symptoms of peri-menopause (http://www.webmd.com/menopause/guide-perimenopause#2) are:

  • Hot flashes
  • Reduced sex drive
  • Discomfort and dryness during sex
  • Fatigue
  • Problems sleeping
  • Mood swings
  • Migraines
  • Severe premenstrual syndrome
  • Irregular periods
  • Breast tenderness
  • An urgent need to urinate
  • Urine leakage, particularly when sneezing or coughing

Because some of these symptoms can be caused by other hormone-related conditions, we always recommend getting your hormone levels checked to ensure that you receive an accurate diagnosis. If you visit AAI Rejuvenation Clinic with the above symptoms, we will measure the levels of your sex hormones as part of our work up. This will allow us to develop a specific program to make you feel like your old self.

Alleviate Your Symptoms with Hormone-Replacement Therapy (HRT)

Unfortunately, the transition from fertility to menopause is part of natural aging and it happens to all women. Although the symptoms of perimenopause can be severe, it is possible to reduce their severity and be able to function fully.

For many years, HRT was used to alleviate the symptoms of peri-menopause and reduce the risk of mortality, dementia, cardiovascular disease, and osteoporosis in aging women. Although a now-revised link to an increased risk of breast cancer led to a temporary decline in the use of HRT, it is again the number one treatment and disease-prevention strategy used in peri-menopausal and menopausal women [4].

As the name suggests, the aim of HRT is to replace the hormones no longer being produced naturally. The hormones are often delivered in tablet form, although transdermal Testosterone Patches, creams, Testosterone Gels, and implants can also be used. There are four major forms of HRT:

  • Estrogen alone
  • Estrogen and progesterone
  • Gonadomimetics, which contain estrogen, progesterone, and testosterone; an example is a tibolone
  • SERMs (selective estrogen receptor modulators)

Because HRT can restore your hormone levels to those you experienced when you were young, it can relieve your symptoms and also reduce the risk of diseases associated with low hormone levels such as osteoporosis and cardiovascular disease. Although some studies have suggested that HRT could protect against stroke, diabetes, cognitive aging, and mood, these effects are more controversial [5]. Nevertheless, the clinical evidence supporting the beneficial effects of HRT in cardiovascular disease and osteoporosis is convincing:

  • HRT reduces the risk of cardiovascular diseases. An evidence-based study investigated the evidence from randomized clinical trials and concluded that HRT could reduce the risk of mortality and cardiovascular disease in women within 10 years of the menopause aged <60 years [5]. However, there is evidence that HRT should be avoided in older women because it might increase the risk of coronary events [6].
  • HRT reduces the risk of osteoporosis. One of the best-known benefits of HRT is its ability to inhibit bone loss and reduce the incidence of fractures in perimenopausal women; estrogen therapy might be more effective than combined estrogen-progesterone treatment [7].

In addition to these clinical effects, HRT alleviates the symptoms of peri-menopause including skin and hair complaints and sexual symptoms [8], as well as hot flashes [9].

Measure your hormone levels today and find out if HRT could improve your day-to-day life.

References

  • [1] R.E. Jones, K.H. Lopez, Human reproductive biology, Academic Press2006.
  • [2] S.J. Richardson, The biological basis of the menopause, Bailliere’s clinical endocrinology and metabolism, 7 (1993) 1-16.
  • [3] L. Jia, H. Jin, J. Zhou, L. Chen, Y. Lu, Y. Ming, Y. Yu, A potential anti-tumor herbal medicine, Corilagin, inhibits ovarian cancer cell growth through blocking the TGF-beta signaling pathways, BMC complementary, and alternative medicine, 13 (2013) 33.
  • [4] R.A. Lobo, J.H. Pickar, J.C. Stevenson, W.J. Mack, H.N. Hodis, Back to the future: Hormone replacement therapy as part of a prevention strategy for women at the onset of menopause, Atherosclerosis, 254 (2016) 282-290.
  • [5] R. Sood, S.S. Faubion, C.L. Kuhle, J.M. Thielen, L.T. Shuster, Prescribing menopausal hormone therapy: an evidence-based approach, International Journal of Women’s Health, 6 (2014) 47-57.
  • [6] R.A. Lobo, Where are we 10 years after the Women’s Health Initiative?, The Journal of clinical endocrinology and metabolism, 98 (2013) 1771-1780.
  • [7] The 2012 hormone therapy position statement of The North American Menopause Society, Menopause (New York, N.Y.), 19 (2012) 257-271.
  • [8] D. Rouskova, K. Mittmann, U. Schumacher, H. Dietrich, T. Zimmermann, Effectiveness, tolerability and acceptance of an oral estradiol/levonorgestrel formulation for the treatment of menopausal complaints: a non-interventional observational study over six cycles of 28 days, Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 30 (2014) 712-716.
  • [9] N. Santoro, C.N. Epperson, S.B. Mathews, Menopausal Symptoms and Their Management, Endocrinology and metabolism clinics of North America, 44 (2015) 497-515.