Side Effects of Testosterone
As with any medication, there is a possibility of side effects from the administration of injectable testosterone therapy. Keep in mind that AAI Rejuvenation Clinic’s contracted, US-based pharmacies only use bioidentical testosterone. Bioidentical means that it is the same as your body produces. Most medications that your primary care physician would prescribe are synthetic, and are subject to an increased possibility of side effects.
Testosterone therapy can be life transforming for men experiencing symptoms of low testosterone; hypogonadism, delayed puberty, impotence, or other hormonal imbalances. Women may also be treated with testosterone injections therapy in cases where breast cancer has spread to other areas of their body. Although side effects are common with improperly supervised testosterone regimens, bear in mind that properly administered testosterone at dosages pertinent to the individual patient’s file characteristics accompanied by preventive, supplemental nutraceuticals can be an invaluable tool to optimize an individual’s health. Patients that participate in physician-supervised protocols mostly have successful, beneficial experiences, with little to no side effects.
The severity of any side effects experienced may depend on the dose used and the individual patient characteristics. The testosterone dose prescribed will vary depending on the sex, age, and diagnosis of the patient. The dose will also be adjusted according to the patient’s response. Injectable testosterone may also interact with blood thinners, insulin or oral diabetes medication, or steroids. Tell your doctor about all medications you use. Injectable testosterone must not be used during pregnancy because it may harm the fetus. Consult your doctor to discuss birth control. Breast-feeding while using this drug is not recommended.
If the testes do not receive the signals to stimulate endogenous testosterone production for several weeks because of consistently high circulating testosterone levels, it can eventually lead to testicular atrophy.
This is one of the reasons that AAI Rejuvenation Clinic prescribing physicians incorporate human chorionic gonadotropin (hCG) in all testosterone-replacement protocols. hCG functions similarly to GnRH to stimulate the production of LH and FSH, which in turn activate endogenous testosterone production in the testes. Some physicians believe that it is not necessary to include hCG in the treatment protocols for patients receiving testosterone therapy; they may instead suggest it only as part of a PCT to help reactivate the testosterone-production system and regress any testosterone atrophy that has occurred.
At AAI Rejuvenation Clinic, we believe that avoiding the side effects of testosterone therapy should be a top priority. We believe that preventative measures are the safest route for anyone interested in testosterone-, hGH– or, any hormone-based program. Our physicians include hCG as part of the main testosterone regimen because it maintains the functionality of the testes during therapy. Although the brain senses that testosterone levels are healthy and elevated (due to treatment) and does not stimulate GnRH (and subsequently LH) production, hCG stimulates LH production and hence testicular testosterone production regardless. Administering hCG throughout the course of therapy ensures that there is no atrophy to reverse.
Even though we administer hCG, our physicians still structure an effective PCT regimen to maximize therapeutic efficacy and ensure that testicular health and size are maintained. The PCT period usually consists of administering hCG for 5–20 consecutive days, depending on individual patient needs. The PCT period may be extended in patients who have suffered any form of testosterone-related side effects. Additional supplementations typically accompany hCG in the PCT, according to the individual patient’s blood work and file details.
Estrogen Accumulation via Aromatization
Another side effect of testosterone therapy is elevated estrogen levels. High levels of testosterone increase circulating estrogen levels in two ways. The first is by displacing estrogen from a serum carrier known as sex hormone-binding globulin (SHBG). The second is by converting free testosterone to estradiol (a type of estrogen) in tissues such as the testes, muscle, and bone via a process known as aromatization.
Although men require some estrogen for muscle production and hormone balance, the presence of too much estrogen leads to side effects including:
• Gynecomastia (breast development)
• Water retention
• Adiposity (the accumulation of fat)
• Mood swings
• Prostate problems
• Erectile dysfunction
• Low libido
If you receive your testosterone replacement therapy from AAI Rejuvenation Clinic, you do not need to worry about these potentially serious or embarrassing side effects. When your AAI Clinic physician designs your testosterone protocol, it will include an anti-estrogen agent or aromatase inhibitor, if necessary, to help ensure that you never experience these side effects. Each patient is different, and aromatizes testosterone at a different rate. This is where blood work is crucial. Once our prescribing physicians can map an individual patient’s reaction to therapy and their aromatization rate, they can structure the patient’s testosterone therapy accordingly. This means including the amount of anti-estrogen or aromatase inhibitor necessary to prevent estrogen accumulation. Following your protocol to the letter is the best way to minimize or prevent and side effects or adverse reactions.
Cardiac Side Effects
Testosterone is a potent antioxidant, and many heart conditions are associated with low testosterone levels. For example, men suffering from hypogonadism have acutely low testosterone levels and are at much greater risk of atherosclerosis. Nevertheless, the misuse or abuse of testosterone therapy, including following a therapeutic program that does not contain the necessary supporting nutraceuticals, can increase the risk of cardiac issues.
AAI Clinics incorporate vitamin B12 into our protocols specifically to combat this risk. Although many patients think that the inclusion of B12 is to improve energy levels, it is actually much more important than that. This is why educating yourself into the purpose of each supplement is critical, because a lack of understanding could lead to a patient making the mistake of skipping that portion of the therapy. Our team is specifically educated in these details and eager to help teach you so that you can get the most from your testosterone therapy.
Being on testosterone therapy for prolonged periods of time without proper breaks, with no supporting nutraceuticals, or when supratherapeutic doses are administered may result in atherosclerosis. This is a very dangerous possible side effect of testosterone therapy, and it must not be taken lightly. Therefore, it is imperative to take all your medications as directed by your prescribing physician. Skipping or removing medications from the structured protocol can cause serious future issues. Your AAI physician will supply you with the medications necessary to maximize the effects of your protocol, ensuring a safe, effective program with little to no side effects.
As described above, increasing testosterone levels using testosterone therapy inhibits sperm production in the testes by blocking the production of FSH. Again, this happens because there is no need for production, as the testosterone therapy has done all the work for the body. The prolonged use of testosterone therapy may ultimately cause a drop in your sperm production, hindering the possibility of having children. This particular testosterone side effect is difficult to avoid and must be taken into careful consideration by men interested in growing their families.
Psychological Side Effects
Some of the most common side effects associated with testosterone are psychological and behavioral. The long-term use of testosterone without the appropriate supervision, blood work, supportive medications, and supplements can lead to mood and behavioral changes such as anxiety, aggressiveness, violence, irritability, and anger. These changes might be more prominent in adolescents. The long-term use of high doses of testosterone can also kill nerve cells in the brain and cause cognitive impairment, which could persist even after therapy.
Side Effects in Women
Women administering any form of testosterone must be aware of the potential of developing typically male characteristics such as facial hair, deepening of the voice, and changes in the skin. These side effects could be irreversible if testosterone treatment is continued.
Call your doctor right away if you notice any of these signs:
• Changes in your menstrual periods
• Male-pattern hair growth (such as on the chin or chest);
• Male pattern baldness
• Enlarged clitoris
• Increase or decrease in sex drive
Decreased Therapeutic Benefits
Improperly administered testosterone therapy is very common because it feels GREAT when you first start, and you cannot imagine needing anything else. Unfortunately, that bliss is very short-lived. When your LH and FSH levels drop too low, the benefits of the therapy are limited. There is no way to avoid this side effect, and so close monitoring of your hormone levels is essential. Men that have been on treatment and experience a decrease in benefits, or even a reversal, do so because they were not receiving proper guidance and nothing was done to prevent the negative biological responses to elevating testosterone levels. This is where AAI Rejuvenation Clinic can help you. Our expertise is in promoting real hormone replacement with little to no side effects, and helping patients who experience side effects correct their programs to get their lives and hormone levels back in order.
These Are Serious Side Effects. Should I Really Go on Therapy?
Quite simply, if you have low testosterone levels you cannot be, act, relate to, or have the potential of the man you once were. It WILL catch up with you. So, we understand that testosterone therapy is necessary, but at what cost? Do not worry, because you do not need to suffer from the negative side effects of testosterone.
Although there are some serious potential side effects with testosterone therapy if not managed correctly, most of the general, public consensus of testosterone therapy is based on the illegal use by groups of individuals such as:
• Sports and fitness enthusiasts
For the most part, these individuals administer the medications with guidance from representatives with ulterior motives, use supraphysiological doses of drugs and complex stacking treatment protocols combining multiple anabolic steroids, and obtain their medications from illegal, untrusted or unregulated sources. Combined, these choices can lead to a vast array or serious and potentially fatal side effects.
What Will AAI do About These Side Effects?
One of the unique aspects of AAI Rejuvenation Clinic is that we welcome patients that have been on improper protocols in the past. Many of our patients have experienced side effects because their testosterone replacement therapy was not properly organized and supervised by a professional. Patients that have self-diagnosed or been treated improperly and have suffered the adverse side effects associated with inappropriate testosterone therapy find relief at AAI Clinics. Our physicians specialize in helping patients with unbalanced hormone levels bring them back in line and, more importantly, help fix any damaged done as a result of the improper protocol. We can help combat your testosterone-related side effects.
AAI Rejuvenation Clinic’s physicians only prescribe protocols that include the medications necessary to ensure the best outcome with the least transitional issues. This is another reason recent why regularly updated blood work is the best thing to base a hormone-replacement program on. The more accurate the details available to the physician prescribing the patient’s testosterone therapy and supportive nutraceuticals, the more successful the protocol is likely to be.
All AAI Rejuvenation Clinic programs include all the additional supporting medications and nutraceuticals necessary to minimize or prevent all the above-mentioned side effects.
With AAI Clinics:
• You will have an established, assigned Wellness Advisor who is available 7 days a week until 10 pm
• You can access the details of your protocol and program information at any time using our mobile app
• You will have an annual phone or personal consultation with your prescribing physician
• If you are a VIP patient, you will receive one free blood test a year
• You will receive products from only Grade “A” pharmacies with the highest recorded purity levels (documentation available)
AAI Rejuvenation Clinic will help you reach your goals. Call us with no cost or obligation. We believe that just one conversation with our friendly staff will make you immediately aware that you called the right place; a clinic that will help you the right way. Please fill out our Contact Form and one of our helpful advisors will contact you within the next 24 business hours to discuss your concerns and potential options.
Summary of the Side Effects
Some of the manageable side effects associated with testosterone use are as follows:
• Myalgia or abnormal muscle growth (because testosterone can build muscle mass, but not strengthen the tendons and ligaments that connect the muscle to bones)
• Kidney damage
• Skin color changes
• Increased/Decreased sexual interest
• Oily skin
• Hair loss
• Breast swelling in men
• Numbness or tingly feeling
• Nausea and vomiting
• Pain, swelling, and redness at the injection site
• Increased thirst
• Increased urination
• Muscle twitching
• Gynecomastia (breast development in men)
However, more serious side effects have also been reported. Contact your doctor immediately if you experience any of the following:
• Increased or ongoing erection of the penis
• Bone pain
• Insulin resistance (which presents as increased thirst and urination)
• Memory problems
• Stomach pain
• Loss of appetite
• Liver damage (which presents as jaundice [yellowing of the skin or eyes])
• Coagulation abnormalities
• Kidney damage
Seek immediate emergency medical help if you experience some or any of the following signs of an allergic reaction, including:
• Difficulty breathing
• Swelling of your face, lips, tongue, or throat
Potential psychological side effects include:
• Increased aggression and hostility
• Mood swings